All Relations between 5-ht receptor 1a and ventral tegmental area of tsai

Publication Sentence Publish Date Extraction Date Species
Noelia Cantero-García, Antonio Flores-Burgess, Juan Pedro Pineda-Gómez, Laura Orio, Antonia Serrano, Zaida Díaz-Cabiale, Carmelo Milló. Galanin N-terminal fragment (1-15) reduces alcohol seeking and alcohol relapse in rats: Involvement of mesocorticolimbic system. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 153. 2022-09-09. PMID:36076594. notably, the mechanism of gal(1-15)-mediated actions involved changes in c-fos, dopamine receptors and 5ht1a expression in the ventral tegmental area, accumbens nucleus and prefrontal cortex. 2022-09-09 2023-08-14 rat
Shawn Zheng Kai Tan, Yasin Temel, Ariel Yovela Chan, Andrea Tsz Ching Mok, Jose Angelo Udal Perucho, Arjan Blokland, Luca Aquili, Wei Ling Lim, Lee Wei Li. Serotonergic treatment normalizes midbrain dopaminergic neuron increase after periaqueductal gray stimulation. Brain structure & function. vol 225. issue 7. 2021-07-06. PMID:32594260. overall, we showed that chronic treatment with an ssri and a 5-ht1a agonist reduced anticipatory freezing behaviour which seems to be associated, through correlative studies, with a reversal of dlpag stimulation induced increase in number of dopaminergic neurons in the vta and/or snpc. 2021-07-06 2023-08-13 rat
Chris A Oosterhof, Mostafa El Mansari, Pierre Blie. Acute effects of brexpiprazole on serotonin, dopamine, and norepinephrine systems: an in vivo electrophysiologic characterization. The Journal of pharmacology and experimental therapeutics. vol 351. issue 3. 2015-02-17. PMID:25225185. in addition, the effects on 5-ht1a autoreceptors in the dorsal raphe nucleus (drn) and d2 autoreceptors in the ventral tegmental area (vta) were compared with those of aripiprazole, an agent in wide clinical use. 2015-02-17 2023-08-13 Not clear
B Gronie. Involvement of glutamate neurotransmission and N-methyl-d-aspartate receptor in the activation of midbrain dopamine neurons by 5-HT1A receptor agonists: an electrophysiological study in the rat. Neuroscience. vol 156. issue 4. 2009-04-14. PMID:18801415. these results show that activation of midbrain dopamine neurons by the systemic administration of 5-ht1a agonists does involve the inactivation of a tonic gabaergic tone, involving mainly the gabab receptors, probably leading to the stimulation of a glutamatergic excitatory drive from the pfc to the vta and an increase in glutamate release. 2009-04-14 2023-08-12 rat
B Gronie. Involvement of glutamate neurotransmission and N-methyl-d-aspartate receptor in the activation of midbrain dopamine neurons by 5-HT1A receptor agonists: an electrophysiological study in the rat. Neuroscience. vol 156. issue 4. 2009-04-14. PMID:18801415. we have examined if this activation is dependent on glutamatergic, serotonergic and gabaergic neurotransmission and if 5-ht1a receptors located within the vta or within the prefrontal cortex (pfc) could contribute. 2009-04-14 2023-08-12 rat
B Gronie. Involvement of glutamate neurotransmission and N-methyl-d-aspartate receptor in the activation of midbrain dopamine neurons by 5-HT1A receptor agonists: an electrophysiological study in the rat. Neuroscience. vol 156. issue 4. 2009-04-14. PMID:18801415. systemic administration of selective 5-ht1a agonists, such as 8-hydroxy-2-(di-n-propylamino)-tetralin (8-ohdpat), stimulates the electrical activity of ventral tegmental area (vta) dopamine neurons by a mechanism which remains unknown. 2009-04-14 2023-08-12 rat
B Gronie. Involvement of glutamate neurotransmission and N-methyl-d-aspartate receptor in the activation of midbrain dopamine neurons by 5-HT1A receptor agonists: an electrophysiological study in the rat. Neuroscience. vol 156. issue 4. 2009-04-14. PMID:18801415. furthermore, our results suggest that some 5-ht1a receptors located within the vta may also participate in this activation. 2009-04-14 2023-08-12 rat
B Gronie. Involvement of glutamate neurotransmission and N-methyl-d-aspartate receptor in the activation of midbrain dopamine neurons by 5-HT1A receptor agonists: an electrophysiological study in the rat. Neuroscience. vol 156. issue 4. 2009-04-14. PMID:18801415. inactivation of the local 5-ht1a receptors by the microinfusion within the vta of the selective 5-ht1a antagonist n-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-n-2-pyridinylcyclohexanecarboxamide maleate (way 100,635), or of pertussis toxin, reduced the ability of 8-ohdpat to stimulate the firing of dopamine neurons but not their burst activity. 2009-04-14 2023-08-12 rat
K Wedzony, A Chocyk, W Kolasiewicz, M Maćkowia. Glutamatergic neurons of rat medial prefrontal cortex innervating the ventral tegmental area are positive for serotonin 5-HT1A receptor protein. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 58. issue 4. 2008-04-24. PMID:18195476. the present study was designed to investigate whether serotonin 5-ht1a receptor protein (5-ht1a receptor-immunoreactivity), is present on cortical pyramidal neurons of the rat medial prefrontal cortex (mpc) innervating the ventral tegmental area (vta). 2008-04-24 2023-08-12 rat
K Wedzony, A Chocyk, W Kolasiewicz, M Maćkowia. Glutamatergic neurons of rat medial prefrontal cortex innervating the ventral tegmental area are positive for serotonin 5-HT1A receptor protein. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 58. issue 4. 2008-04-24. PMID:18195476. these anatomical data indicate that serotonin 5-ht1a receptors might potentially control the excitability and propagation of information transmitted by the pyramidal cells to the vta. 2008-04-24 2023-08-12 rat
K Wedzony, A Chocyk, W Kolasiewicz, M Maćkowia. Glutamatergic neurons of rat medial prefrontal cortex innervating the ventral tegmental area are positive for serotonin 5-HT1A receptor protein. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 58. issue 4. 2008-04-24. PMID:18195476. moreover, our results indicate that the drugs operating via serotonin 5-ht1a receptors in the mpc, might control from this level the release of glutamate in the vta and restore function of glutamate neurotransmission, whose dysfunction is observed for example in schizophrenia. 2008-04-24 2023-08-12 rat
K Wedzony, A Chocyk, W Kolasiewicz, M Maćkowia. Glutamatergic neurons of rat medial prefrontal cortex innervating the ventral tegmental area are positive for serotonin 5-HT1A receptor protein. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 58. issue 4. 2008-04-24. PMID:18195476. it was found that approximately 52% of cells in layers ii/iii of the mpc whose axons initial segments were immunoreactive for serotonin 5ht1a receptor were also labeled with fluoro-gold (fg), a retrograde tracer injected into the vta, indicating that certain portion of neurons forming glutamatergic innervations of the vta may be controlled by serotonin 5-ht1a receptors. 2008-04-24 2023-08-12 rat
K Wedzony, A Chocyk, W Kolasiewicz, M Maćkowia. Glutamatergic neurons of rat medial prefrontal cortex innervating the ventral tegmental area are positive for serotonin 5-HT1A receptor protein. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 58. issue 4. 2008-04-24. PMID:18195476. glutamatergic neurons of rat medial prefrontal cortex innervating the ventral tegmental area are positive for serotonin 5-ht1a receptor protein. 2008-04-24 2023-08-12 rat
Llorenç Díaz-Mataix, Francesc Artigas, Pau Celad. Activation of pyramidal cells in rat medial prefrontal cortex projecting to ventral tegmental area by a 5-HT1A receptor agonist. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 16. issue 4. 2006-08-04. PMID:16290106. activation of pyramidal cells in rat medial prefrontal cortex projecting to ventral tegmental area by a 5-ht1a receptor agonist. 2006-08-04 2023-08-12 rat
Llorenç Díaz-Mataix, M Cecilia Scorza, Analía Bortolozzi, Miklos Toth, Pau Celada, Francesc Artiga. Involvement of 5-HT1A receptors in prefrontal cortex in the modulation of dopaminergic activity: role in atypical antipsychotic action. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 47. 2006-03-07. PMID:16306396. the selective 5-ht1a antagonist way-100635 reversed the effects of bay in both areas, and the changes in the vta were prevented by frontocortical transection. 2006-03-07 2023-08-12 mouse
Llorenç Díaz-Mataix, M Cecilia Scorza, Analía Bortolozzi, Miklos Toth, Pau Celada, Francesc Artiga. Involvement of 5-HT1A receptors in prefrontal cortex in the modulation of dopaminergic activity: role in atypical antipsychotic action. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 47. 2006-03-07. PMID:16306396. these results suggest that the activation of mpfc 5-ht1a receptors enhances the activity of vta da neurons and mesocortical da release. 2006-03-07 2023-08-12 mouse
Qing-Shan Yan, Shi-Zhong Zheng, Mei-Jiang Feng, Shu-E Ya. Involvement of 5-HT1B receptors within the ventral tegmental area in ethanol-induced increases in mesolimbic dopaminergic transmission. Brain research. vol 1060. issue 1-2. 2005-12-20. PMID:16212943. these ethanol-induced increases of the da release in the vta and the nacc were significantly attenuated by intra-tegmental infusion of sb 216641 (a 5-ht(1b) receptor antagonist), but not brl 15572 (a 5-ht(1d/1a) receptor antagonist) or way 100635 (a 5-ht1a receptor antagonist). 2005-12-20 2023-08-12 rat
William J McBride, Richard L Bell, Zachary A Rodd, Wendy N Strother, James M Murph. Adolescent alcohol drinking and its long-range consequences. Studies with animal models. Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism. vol 17. 2005-05-03. PMID:15789863. the early age-of-onset of alcohol drinking in the p compared to the np line is associated with (a) higher densities of serotonin-1a (5-ht1a) receptors in cerebral cortical and hippocampal regions; (b) lower densities of dopamine (da) d2 receptors in the ventral tegmental area (vta); (c) higher functional activity in several limbic, cortical and hippocampal regions; and (d) sensitivity to the low-dose stimulating effect of ethanol. 2005-05-03 2023-08-12 rat
Qing-Shan Yan, Shi-Zhong Zheng, Shu-E Ya. Involvement of 5-HT1B receptors within the ventral tegmental area in regulation of mesolimbic dopaminergic neuronal activity via GABA mechanisms: a study with dual-probe microdialysis. Brain research. vol 1021. issue 1. 2004-11-08. PMID:15328035. co-infusion of the 5-ht1b receptor antagonist sb 216641 (10 microm), but not the 5-ht1a receptor antagonist way 100635 (10 microm) or the 5-ht1d/1a receptor antagonist brl 15572 (10 microm), antagonized not only the effects of intra-tegmental cp 93129 (80 microm) on vta da and nac da but also on vta gaba. 2004-11-08 2023-08-12 rat
M D Doherty, V M Picke. Targeting of serotonin 1A receptors to dopaminergic neurons within the parabrachial subdivision of the ventral tegmental area in rat brain. The Journal of comparative neurology. vol 433. issue 3. 2001-07-12. PMID:11298363. we therefore examined the ultrastructural immunocytochemical localization of the 5-ht1a receptor in the parabrachial (vtapb) and paranigral (vtapn) subdivisions of rat vta, to determine 1) the functional sites for receptor activation, and 2) the cellular associations between this receptor and dopaminergic neurons identified by their tyrosine hydroxylase (th) content. 2001-07-12 2023-08-12 rat