All Relations between 5-ht receptor 1a and serotonin

Reference Sentence Publish Date Extraction Date Species
Jiajia Dai, Hyangin Kim, Zerong You, Michael F McCabe, Shuzhuo Zhang, Shiyu Wang, Grewo Lim, Lucy Chen, Jianren Ma. Role of 5-HT1A-mediated upregulation of brain indoleamine 2,3 dioxygenase 1 in the reduced antidepressant and antihyperalgesic effects of fluoxetine during maintenance treatment. Frontiers in pharmacology vol 13 issue 2023 36588734 fluoxetine exposure induced upregulation of the 5-hydroxytryptamine 1a (5-ht1a) auto-receptor and indoleamine 2,3 dioxygenase 1 (ido1, a rate-limiting enzyme of tryptophan metabolism) in the brainstem dorsal raphe nucleus (drn), which shifted the tryptophan metabolism away from the 5-ht biosynthesis. 2023-01-02 2023-01-05 Not clear
Jo\\xc3\\xa3o P F Kurita, Anderson H F F Le\\xc3\\xa3o, Vinicius S Bioni, Raphael Wuo-Silva, Alvaro C Lima, Murilo A Paiva-Santos, Gabriela F Marinho, D\\xc3\\xa9bora M G Cunha, Marcela Becegato, Leonardo B Lopes-Silva, Alessandra M Ribeiro, Regina H Silv. Memory and anxiety-like behavior of rats in the plus-maze discriminative avoidance task: Role of serotonergic transmission in the basolateral amygdala. Behavioral neuroscience vol issue 2022 36548050 the results showed that an increase in serotonin (5-ht) availability or the blockade of 5ht1a and 5ht2a bla receptors impaired aversive memory formation. 2022-12-22 2022-12-28 Not clear
Martin Kubitschke, Monika M\\xc3\\xbcller, Lutz Wallhorn, Mauro Pulin, Manuel Mittag, Stefan Pollok, Tim Ziebarth, Svenja Bremshey, Jill Gerdey, Kristin Carolin Claussen, Kim Renken, Juliana Gro\\xc3\\x9f, Pascal Gnei\\xc3\\x9fe, Niklas Meyer, J Simon Wiegert, Andreas Reiner, Martin Fuhrmann, Olivia Andrea Massec. Next generation genetically encoded fluorescent sensors for serotonin. Nature communications vol 13 issue 1 2022 36473867 we developed a family of genetically encoded serotonin (5-ht) sensors (sdarken) on the basis of the native 5-ht1a receptor and circularly permuted gfp. 2022-12-06 2022-12-15 Not clear
Carla V Arga\\xc3\\xb1araz, Tamara S Adjimann, Paula P Perissinotti, Mariano Soiza-Reill. Selective refinement of glutamate and GABA synapses on dorsal raphe 5-HT neurons during postnatal life. Development (Cambridge, England) vol issue 2022 36458556 this refinement of drn inputs is not accompanied by changes in 5-ht1a receptor-mediated inhibition over 5-ht neurons. 2022-12-02 2022-12-08 Not clear
Ho-Geun Kang, Hee-Yun Kim, Hyunwoo Jee, Hwanseok Jun, Hosong Cho, Dongjun Park, Hyun-Jong Ahn, Hyung-Min Kim, Hyun-Ja Jeon. Compound of Cynanchum wilfordii and Humulus lupulus L. Ameliorates Menopausal Symptoms in Ovariectomized Mice. Reproductive sciences (Thousand Oaks, Calif.) vol issue 2022 36333646 values for hypothalamic serotonin (5-ht), dopamine, norepinephrine, estrogen receptor (er)-\xce\xb2, 5-ht1a, and 5-ht2a were significantly enhanced, while value for hypothalamic monoamine oxidase a was reduced in cwhl and caudatin groups compared with the ovx group. 2022-11-05 2022-11-08 Not clear
Arnauld Belmer, Ronan Depoortere, Kate Beecher, Adrian Newman-Tancredi, Selena E Bartlet. Neural serotonergic circuits for controlling long-term voluntary alcohol consumption in mice. Molecular psychiatry vol issue 2022 36195637 we have previously shown using the "drinking-in-the-dark" model in mice that the stimulation of the serotonin receptor 1a (5-ht 2022-10-04 2022-10-10 Not clear
Cheng-Jie Li, Li-Ge Zhang, Lu-Bing Liu, Meng-Qi An, Li-Guo Dong, Han-Ying Gu, Yong-Ping Dai, Fen Wang, Cheng-Jie Mao, Chun-Feng Li. Inhibition of Spinal 5-HT3 Receptor and Spinal Dorsal Horn Neuronal Excitability Alleviates Hyperalgesia in a Rat Model of Parkinson's Disease. Molecular neurobiology vol issue 2022 36168076 several 5-ht receptor subtypes have been confirmed to be associated with nociception in the spinal cord, such as 5-ht1a receptor, 5-ht1b receptor, 5-ht2 receptor, 5-ht3 receptor, and 5-ht7 receptor. 2022-09-28 2022-09-29 Not clear
Bernardo Lopez-Torres, Irma Ares, Marta Mart\\xc3\\xadnez, Jorge-Enrique Maximiliano, Mar\\xc3\\xada-Rosa Mart\\xc3\\xadnez-Larra\\xc3\\xb1aga, Arturo Anad\\xc3\\xb3n, Mar\\xc3\\xada-Ar\\xc3\\xa1nzazu Mart\\xc3\\xadne. Neurotoxicity induced by the pyrethroid lambda-cyhalothrin: Alterations in monoaminergic systems and dopaminergic and serotoninergic pathways in the rat brain. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association vol 169 issue 2022 36126889 this research study also showed in hippocampus and prefrontal cortex, that lambda-cyhalothrin modified the mrna levels of da transporter gene (dat1 up-regulation), 5-ht transporter gene (sert down-regulation), da receptor genes (drd1and drd2 down-regulation), 5-ht receptor genes (5-ht1a and 5-ht2a down-regulation/up-regulation), da synthesis gene (th down-regulation), 5-ht synthesis gene (tph2 down-regulation), da and 5-ht degradation genes (maoa and maob up-regulation). 2022-09-27 2022-09-29 Not clear
I E Sorokin, V S Evsyukova, A V Kuliko. Effect of Short Photoperiod on the Behavior and Brain Serotonin System in Zebrafish Danio rerio. Bulletin of experimental biology and medicine vol issue 2022 35844021 we studied changes in the behavior, content of 5-ht and its major metabolite 5-hydroxyindoleacetic acid (5-hiaa), and the expression of genes encoding the key enzymes of 5-ht metabolism, tryptophan hydroxylases tph1a, tph1b, tph2, monoamine oxidase (mao), 5-ht transporter, and 5-ht1a and 5-ht2a receptors in the brain of zebrafish reared for 60 days under short (04:20 h) compared to those reared at normal (12:12 h) photoperiod. 2022-07-17 2022-07-19 Not clear
Raheel Saeed, Khalid Mahmood, Sadia Basharat Ali, Darakhshan Jabeen Halee. Behavioral, Hormonal, and Serotonergic Responses to Different Restricted Feeding Schedules in Rats. International journal of tryptophan research : IJTR vol 15 issue 2022 35757086 to determine the effect of long-term restricted feeding schedules on behavior, serotonergic responses, and neuro-endocrine functions, metabolism of serotonin (5-ht) in the striatum, expression of serotonin-1a (5-ht1a) auto-receptor in the raphe nuclei and circulating levels of leptin and corticosterone were determined in female wistar rats kept on excessive food restriction schedule. 2022-06-27 2022-07-04 Not clear
Raheel Saeed, Khalid Mahmood, Sadia Basharat Ali, Darakhshan Jabeen Halee. Behavioral, Hormonal, and Serotonergic Responses to Different Restricted Feeding Schedules in Rats. International journal of tryptophan research : IJTR vol 15 issue 2022 35757086 these changes in 5-ht metabolism and 5-ht1a auto-receptor expression were more profound in dr animals as compare to trf animals. 2022-06-27 2022-07-04 Not clear
Yusuf Oloruntoyin Ayipo, Waleed A Alananzeh, Sani Najib Yahayaa, Mohd Nizam Mord. Molecular Modelling and Virtual Screening to Identify New Piperazine Derivatives as Potent Human 5-HT1A Antagonists and Reuptake Inhibitors. Combinatorial chemistry & high throughput screening vol issue 2022 35611784 serotonin/5-ht antagonist and reuptake inhibitors (saris) ameliorate depression by increasing the terminal 5-ht through the activation of somatodendritic 5-ht1a autoreceptors. 2022-05-25 2022-06-13 Not clear
Brandon L Oliver, McKenna Burdette, Alma E Pahua, Cassandra Cavazos, Cheyenne A Morales, Bryan D Alvarez, Dionisio A Amode. Acute serotonin 1B/1A receptor activation impairs behavioral flexibility in C57BL/6J mice. Behavioural brain research vol issue 2022 35367298 pharmacological activation of the serotonin (5-ht) 1b and 5-ht1a receptors has been shown to induce ocd-like perseverative circling and locomotor stereotypy in rodents. 2022-04-03 2022-04-14 Not clear
Anurag Chaudhary, Kalpana Singh, Nishant Verma, Sachin Kumar, Deepak Kumar, Prince Prashant Sharm. Chromenes - A Novel Class of Heterocyclic Compounds: Recent Advancements and Future Directions. Mini reviews in medicinal chemistry vol issue 2022 35362382 structural modifications at the chromene ring, middle aliphatic portion, and terminal aromatic ring yielded more potential 5-ht1a (5-hydroxytryptamine 1a) receptor affinity and antidiabetic activity. 2022-04-01 2022-04-14 Not clear
Robert W Garvey, Enza Lacivita, Mauro Niso, Beata Duszy\\xc5\\x84ska, Paul E Harris, Marcello Leopold. Design, synthesis, and characterization of a novel fluoroprobe for live human islet cell imaging of serotonin 5-HT1A receptor. ChemMedChem vol issue 2022 35286016 among the 5-ht receptor subtype found in pancreatic islets, serotonin receptor 1a (5-ht 1a ) demonstrates a unique ability to inhibit beta-cell insulin secretion. 2022-03-14 2022-04-14 Not clear
Den\\xc3\\xa9 A Voisin, Alison Wakeford, Jonathon Nye, Jiyoung Mun, Sara R Jones, Jason Locke, Kim L Huhman, Mark E Wilson, H Elliott Albers, Vasiliki Michopoulo. Sex and social status modify the effects of fluoxetine on socioemotional behaviors in Syrian hamsters and rhesus macaques. Pharmacology, biochemistry, and behavior vol issue 2022 35219757 fluoxetine, a selective serotonin (5ht) reuptake inhibitor whose actions are mediated in part by the 5ht1a receptor (5ht1ar), has sex- and social status-specific effects on socioemotional behavior and aggressive behavior. 2022-03-06 2022-03-02 Not clear
Den\\xc3\\xa9 A Voisin, Alison Wakeford, Jonathon Nye, Jiyoung Mun, Sara R Jones, Jason Locke, Kim L Huhman, Mark E Wilson, H Elliott Albers, Vasiliki Michopoulo. Sex and social status modify the effects of fluoxetine on socioemotional behaviors in Syrian hamsters and rhesus macaques. Pharmacology, biochemistry, and behavior vol issue 2022 35219757 fluoxetine, a selective serotonin (5ht) reuptake inhibitor whose actions are mediated in part by the 5ht1a receptor (5ht1ar), has sex- and social status-specific effects on socioemotional behavior and aggressive behavior. 2022-02-27 2022-03-02 Not clear
Rie Tohge, Satoshi Kaneko, Satoshi Morise, Mitsuaki Oki, Norihiro Takenouchi, Aya Murakami, Masataka Nakamura, Hirofumi Kusaka, Yusuke Yakushij. Zonisamide attenuates the severity of levodopa-induced dyskinesia via modulation of the striatal serotonergic system in a rat model of Parkinson's disease. Neuropharmacology vol 198 issue 2021 34474045 continuously levodopa-infused rats or intermittently zns-injected rats did not develop aims, and no differences in the expression of brain-derived neurotrophic factor, 5-ht transporter, 5ht1a, and 5ht1b mrna between the lesioned striatum and normal side were observed. 2022-02-04 2022-01-14 Not clear
Lila Wollman, Andrew Hill, Brady Hasse, Christina Young, Giovanni Hernandez-De La Pena, Richard B Levine, Ralph F Fregos. Influence of developmental nicotine exposure on serotonergic control of breathing-related motor output. Developmental neurobiology vol issue 2022 35016263 we applied 5ht alone, or together with antagonists of 5ht1a, 5ht2a or 5ht7 receptor subtypes. 2022-02-01 2022-01-13 Not clear
Colleen Synan, Carrie Bowen, David J Heal, Christelle Froger-Coll\\xc3\\xa9aux, Patrick M Beardsley, Nina Dedic, Seth C Hopkins, Una Campbell, Kenneth S Kobla. Ulotaront, a novel TAAR1 agonist with 5-HT1A agonist activity, lacks abuse liability and attenuates cocaine cue-induced relapse in rats. Drug and alcohol dependence vol 231 issue 2022 35033729 ulotaront (sep-363856) is a trace amine-associated receptor 1 (taar1) agonist with 5-hydroxytryptamine type 1a (5-ht1a) agonist activity that is currently in phase 3 clinical development for the treatment of schizophrenia. 2022-01-31 2022-01-27 Not clear
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