All Relations between 5-ht receptor 1a and serotonin

Publication Sentence Publish Date Extraction Date Species
Paul R Albert, Faranak Vahid-Ansar. The 5-HT1A receptor: Signaling to behavior. Biochimie. vol 161. 2019-07-08. PMID:31079617. thus, the 5-ht1a receptor appears to modify its signaling repertoire depending on the cell type (5-ht vs. post-synaptic neurons) and the developmental state of the neuron. 2019-07-08 2023-08-13 Not clear
Paul R Albert, Faranak Vahid-Ansar. The 5-HT1A receptor: Signaling to behavior. Biochimie. vol 161. 2019-07-08. PMID:31079617. in addition, in response to prolonged 5-ht elevation upon chronic antidepressant treatment, the 5-ht1a autoreceptor appears to desensitize more extensively than the heteroreceptor. 2019-07-08 2023-08-13 Not clear
Yong Kee Choi, Nika Adham, Béla Kiss, István Gyertyán, Frank I Taraz. Long-term effects of aripiprazole exposure on monoaminergic and glutamatergic receptor subtypes: comparison with cariprazine. CNS spectrums. vol 22. issue 6. 2019-06-28. PMID:28059046. this study examined the chronic effects of aripiprazole and cariprazine on serotonin (5-ht1a and 5-ht2a) and glutamate (nmda and ampa) receptor subtypes. 2019-06-28 2023-08-13 Not clear
Haixia Zheng, Keiichi Onoda, Yasuko Wada, Shingo Mitaki, Toru Nabika, Shuhei Yamaguch. Serotonin-1A receptor C-1019G polymorphism affects brain functional networks. Scientific reports. vol 7. issue 1. 2019-06-28. PMID:28970569. the serotonin-1a (5-ht1a) receptor is strongly implicated in major depression and other affective disorders due to its negative regulation of serotonin neurone firing rates. 2019-06-28 2023-08-13 human
Danilo De Gregorio, Ryan J McLaughlin, Luca Posa, Rafael Ochoa-Sanchez, Justine Enns, Martha Lopez-Canul, Matthew Aboud, Sabatino Maione, Stefano Comai, Gabriella Gobb. Cannabidiol modulates serotonergic transmission and reverses both allodynia and anxiety-like behavior in a model of neuropathic pain. Pain. vol 160. issue 1. 2019-06-26. PMID:30157131. increasing doses of cbd (0.1-1.0 mg/kg) decreased the firing rate of 5-ht neurons in the dorsal raphe nucleus, which was prevented by administration of the 5-ht1a antagonist way 100635 (0.3 mg/kg, i.v.) 2019-06-26 2023-08-13 rat
Danilo De Gregorio, Ryan J McLaughlin, Luca Posa, Rafael Ochoa-Sanchez, Justine Enns, Martha Lopez-Canul, Matthew Aboud, Sabatino Maione, Stefano Comai, Gabriella Gobb. Cannabidiol modulates serotonergic transmission and reverses both allodynia and anxiety-like behavior in a model of neuropathic pain. Pain. vol 160. issue 1. 2019-06-26. PMID:30157131. repeated treatment with cbd (5 mg/kg/day, subcutaneously [s.c.], for 7 days) increased 5-ht firing through desensitization of 5-ht1a receptors. 2019-06-26 2023-08-13 rat
Danilo De Gregorio, Ryan J McLaughlin, Luca Posa, Rafael Ochoa-Sanchez, Justine Enns, Martha Lopez-Canul, Matthew Aboud, Sabatino Maione, Stefano Comai, Gabriella Gobb. Cannabidiol modulates serotonergic transmission and reverses both allodynia and anxiety-like behavior in a model of neuropathic pain. Pain. vol 160. issue 1. 2019-06-26. PMID:30157131. overall, repeated treatment with low-dose cbd induces analgesia predominantly through trpv1 activation, reduces anxiety through 5-ht1a receptor activation, and rescues impaired 5-ht neurotransmission under neuropathic pain conditions. 2019-06-26 2023-08-13 rat
Faheem Hyder Pottoo, Md Noushad Javed, Md Abul Barkat, Md Sabir Alam, Javaid Ashraf Nowshehri, Dhafer Mahdi Alshayban, Mohammad Azam Ansar. Estrogen and Serotonin: Complexity of Interactions and Implications for Epileptic Seizures and Epileptogenesis. Current neuropharmacology. vol 17. issue 3. 2019-06-03. PMID:29956631. serotonin modulates epileptiform activity in either direction i.e administration of 5-ht agonists or reuptake inhibitors leads to the activation of 5-ht3 and 5-ht1a receptors tending to impede focal and generalized seizures, while depletion of brain 5-ht along with the destruction of serotonergic terminals leads to expanded neuronal excitability hence abatement of seizure threshold in experimental animal models. 2019-06-03 2023-08-13 Not clear
E M Kondaurova, D V Bazovkina, V S Naumenk. [5-HT1A/5-HT7 receptor interplay: Chronic activation of 5-HT7 receptors decreases the functional activity of 5-HT1A receptor and its сontent in the mouse brain]. Molekuliarnaia biologiia. vol 51. issue 1. 2019-04-30. PMID:28251979. serotonin receptors 5-ht1a and 5-ht7 are involved in the development of various psychopathologies. 2019-04-30 2023-08-13 mouse
Eugenia Saiz-Bianco, Jessika Urbanavicius, Giselle Prunell, Patricia Lago. Melanin-concentrating hormone does not modulate serotonin release in primary cultures of fetal raphe nucleus neurons. Neuropeptides. vol 74. 2019-04-15. PMID:30642579. 5-ht extracellular levels were significantly increased by incubation with serotonin reuptake inhibitors (citalopram and nortriptyline) and a monoamine-oxidase inhibitor (clorgyline), and were not significantly modified by a 5-ht1a autoreceptor agonist (8-ohdpat). 2019-04-15 2023-08-13 rat
Li Liu, Mengsi Fu, Siran Pei, Liangliang Zhou, Jing Shan. R-Fluoxetine Increases Melanin Synthesis Through a 5-HT1A/2A Receptor and p38 MAPK Signaling Pathways. International journal of molecular sciences. vol 20. issue 1. 2019-04-03. PMID:30585252. in addition, we found that r-fluoxetine induced melanin synthesis through the serotonin1a receptor (5-ht1a) and serotonin 2a receptor (5-ht2a). 2019-04-03 2023-08-13 human
Mingjun Xiang, Yuting Jiang, Zhiying Hu, Yang Yang, Benson O A Botchway, Marong Fan. Stimulation of Anxiety-Like Behavior via ERK Pathway by Competitive Serotonin Receptors 2A and 1A in Post-Traumatic Stress Disordered Mice. Neuro-Signals. vol 25. issue 1. 2019-03-05. PMID:28977803. serotonin 5ht2a and 5ht1a receptors (5ht2ar, 5ht1ar) have the closest connection to anxiety-like behavior in post-traumatic stress disorder (ptsd). 2019-03-05 2023-08-13 mouse
Daniel G Ehlinger, Kathryn G Common. Cav1.2 L-type calcium channels regulate stress coping behavior via serotonin neurons. Neuropharmacology. vol 144. 2019-03-04. PMID:30176250. we find that 5-ht neuron cacna1c knockout disrupts active-coping behavior in the forced swim test and that this behavioral effect is rescued by blocking 5-ht1a receptors. 2019-03-04 2023-08-13 mouse
Daniel G Ehlinger, Kathryn G Common. Cav1.2 L-type calcium channels regulate stress coping behavior via serotonin neurons. Neuropharmacology. vol 144. 2019-03-04. PMID:30176250. moreover, cacna1c knockout mice display enhanced fos expression in caudal dr 5-ht neurons and an enhanced response to a 5-ht1a receptor antagonist in rostral dr 5-ht neurons, indicating that loss of cacna1c disrupts both 5-ht neuron activation and 5-ht1a dependent feedback inhibition across the caudal to rostral dr. 2019-03-04 2023-08-13 mouse
Daniel G Ehlinger, Kathryn G Common. Cav1.2 L-type calcium channels regulate stress coping behavior via serotonin neurons. Neuropharmacology. vol 144. 2019-03-04. PMID:30176250. collectively, these results reveal an important role for 5-ht neuron cav1.2 ltccs in stress-coping behavior and 5-ht1a receptor function. 2019-03-04 2023-08-13 mouse
Silvia Vincentiis, Juliana Alcantara, Patricia Rzezak, Daniel S Kerr, Wagner F Gattaz, Helio van der Linden, Bernardo Dos Santos, Sebastiao E Melo-Souza, Francisco Arruda, Paulo Ragazzo, Tiffany Chaim-Avancini, Mauricio H Serpa, Fernando Fernandes, Ricardo A Moreno, Geraldo Busatto, Ruda Alessi, Renata Demarque, Kette D Valent. Genetic polymorphisms of the 5HT receptors are not related with depression in temporal lobe epilepsy caused by hippocampal sclerosis. Epilepsy & behavior : E&B. vol 83. 2019-02-25. PMID:29709878. the primary goal of this study was to determine the possible association between polymorphisms of genes encoding the serotonin receptors 5ht1a (rs6295), 5ht1b (rs6296), and 5ht2c (rs6318) and the presence of mood disorders in patients with tle-hs. 2019-02-25 2023-08-13 Not clear
Anna Rita Zuena, Daniela Maftei, Giovanni Sebastiano Alemà, Francesca Dal Moro, Roberta Lattanzi, Paola Casolini, Ferdinando Nicolett. Multimodal antidepressant vortioxetine causes analgesia in a mouse model of chronic neuropathic pain. Molecular pain. vol 14. 2019-02-20. PMID:30289053. vortioxetine is a multimodal antidepressant that potently antagonizes 5-ht3 serotonin receptors, inhibits the high-affinity serotonin transporter, activates 5-ht1a and 5-ht1b receptors, and antagonizes 5-ht1d and 5-ht7 receptors. 2019-02-20 2023-08-13 mouse
Liangliang Zhou, Minxuan Cai, Yingying Ren, Huali Wu, Meng Liu, Haijuan Chen, Jing Shan. The different roles of 5-HT1A/2A receptors in fluoxetine ameliorated pigmentation of C57BL/6 mouse skin in response to stress. Journal of dermatological science. vol 92. issue 3. 2019-02-19. PMID:30527375. 5-ht1a receptor was participated in fluoxetine induced melanogenesis in melanocytes and in normal c57bl/6 mice, but we know little about whether other 5-ht receptors are involved in regulation of fluoxetine promotes pigmentation. 2019-02-19 2023-08-13 mouse
Elske N de Haas, Jerine A J van der Eij. Where in the serotonergic system does it go wrong? Unravelling the route by which the serotonergic system affects feather pecking in chickens. Neuroscience and biobehavioral reviews. vol 95. 2019-02-11. PMID:30055196. genetic associations exist between fp, 5-ht1a and 5-ht1b receptor functioning and metabolism of 5-ht and da. 2019-02-11 2023-08-13 Not clear
Elske N de Haas, Jerine A J van der Eij. Where in the serotonergic system does it go wrong? Unravelling the route by which the serotonergic system affects feather pecking in chickens. Neuroscience and biobehavioral reviews. vol 95. 2019-02-11. PMID:30055196. birds with deficient functioning of the somatodendritic 5-ht1a autoreceptor and 5-ht metabolism appear predisposed to develop fp. 2019-02-11 2023-08-13 Not clear