All Relations between 5-ht receptor 1a and serotonin

Publication Sentence Publish Date Extraction Date Species
J M Casanovas, M Lésourd, F Artiga. The effect of the selective 5-HT1A agonists alnespirone (S-20499) and 8-OH-DPAT on extracellular 5-hydroxytryptamine in different regions of rat brain. British journal of pharmacology. vol 122. issue 4. 1998-01-02. PMID:9375971. the selective 5-ht1a antagonist way-100635 (0.5 mg kg(-1), s.c.) prevented the decrease in 5-ht induced by alnespirone (0.3 mg kg(-1), s.c.) in frontal cortex. 1998-01-02 2023-08-12 rat
J M Casanovas, M Lésourd, F Artiga. The effect of the selective 5-HT1A agonists alnespirone (S-20499) and 8-OH-DPAT on extracellular 5-hydroxytryptamine in different regions of rat brain. British journal of pharmacology. vol 122. issue 4. 1998-01-02. PMID:9375971. this regional selectivity seems unlikely to be accounted for by differences in the sensitivity of 5-ht1a autoreceptors controlling 5-ht release, given the dissimilar effects of these two 5-ht1a agonists in regions rich in cell bodies and nerve terminals. 1998-01-02 2023-08-12 rat
J M Casanovas, M Lésourd, F Artiga. The effect of the selective 5-HT1A agonists alnespirone (S-20499) and 8-OH-DPAT on extracellular 5-hydroxytryptamine in different regions of rat brain. British journal of pharmacology. vol 122. issue 4. 1998-01-02. PMID:9375971. this suggests the presence of complex mechanisms of control of 5-ht release by 5-ht1a receptors. 1998-01-02 2023-08-12 rat
C Fernandes, C R McKittrick, S E File, B S McEwe. Decreased 5-HT1A and increased 5-HT2A receptor binding after chronic corticosterone associated with a behavioural indication of depression but not anxiety. Psychoneuroendocrinology. vol 22. issue 7. 1997-12-30. PMID:9373882. the effects of chronic corticosterone treatment (100 mg pellet implanted for 1 week) were assessed in animal tests of anxiety, exploration and motor activity, and changes in binding to 5-ht1a and 5-ht2a receptors, and the 5-ht transporter, were measured. 1997-12-30 2023-08-12 Not clear
J A Kim, R A Gillespie, M J Drus. Effects of maternal ethanol consumption and buspirone treatment on 5-HT1A and 5-HT2A receptors in offspring. Alcoholism, clinical and experimental research. vol 21. issue 7. 1997-12-16. PMID:9347075. because fetal 5-ht functions as an essential neurotrophic factor, these studies also determined whether treatment of pregnant rats with buspirone, a 5-ht1a agonist, could overcome the effects of the fetal 5-ht deficit and prevent ethanol-associated receptor abnormalities. 1997-12-16 2023-08-12 rat
R A Stone, P J Barnes, K F Chun. Effect of 5-HT1A receptor agonist, 8-OH-DPAT, on cough responses in the conscious guinea pig. European journal of pharmacology. vol 332. issue 2. 1997-12-15. PMID:9286622. we have studied the role for 5-hydroxytryptamine (5-ht) in the modulation of the cough reflex by examining the effect of a selective 5-ht1a receptor agonist, 8-hydroxy-2-(di-n-propylamino) tetralin (8-oh-dpat) on cough and respiratory rate in conscious guinea pigs. 1997-12-15 2023-08-12 Not clear
B J Keck, J M Lakosk. N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ) administration for studies of 5-HT1A receptor binding site inactivation and turnover. Brain research. Brain research protocols. vol 1. issue 4. 1997-12-10. PMID:9384817. while age-related declines in the number of 5-ht1b and 5-ht2 receptors have been reported, little information is available describing the region-specific effects of aging on the functional dynamics of equilibrium binding at 5-ht receptors, including the 5-ht1a receptor subtype. 1997-12-10 2023-08-12 human
B J Keck, J M Lakosk. N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ) administration for studies of 5-HT1A receptor binding site inactivation and turnover. Brain research. Brain research protocols. vol 1. issue 4. 1997-12-10. PMID:9384817. this compound is appropriate for examining the binding profile of several 5-ht receptors, including the 5-ht1a receptor. 1997-12-10 2023-08-12 human
J P Redrobe, M Bouri. Effects of pretreatment with clonidine, lithium and quinine on the activities of antidepressant drugs in the mouse tail suspension test. Fundamental & clinical pharmacology. vol 11. issue 5. 1997-12-08. PMID:9342590. drugs used in the present study included: the tricyclic antidepressants imipramine and dothiepin, the heterocyclic antidepressant trazodone, the 5-ht reuptake inhibitor (ssri) fluoxetine, the atypical antidepressants mianserin and iprindole, the 5-ht1a receptor agonist ipsapirone, the 5-ht2a/2c receptor antagonist ritanserin, and the 5-ht3 receptor antagonist ondansetron. 1997-12-08 2023-08-12 mouse
J Cerdà, T R Petrino, M J Greenberg, R A Wallac. Pharmacology of the serotonergic inhibition of steroid-induced reinitiation of oocyte meiosis in the teleost Fundulus heteroclitus. Molecular reproduction and development. vol 48. issue 2. 1997-12-02. PMID:9291479. the pharmacological profile of these 5-ht receptors is different from those of any known mammalian 5-ht receptor, although they showed some similarities to the 5-ht1a, 5-ht2, and 5-ht3 receptors, as well as to 5-ht receptors on oocytes of some bivalve molluscs. 1997-12-02 2023-08-12 Not clear
M A Joppa, R K Rowe, R L Meise. Effects of serotonin 1A or 1B receptor agonists on social aggression in male and female Syrian hamsters. Pharmacology, biochemistry, and behavior. vol 58. issue 2. 1997-12-01. PMID:9300591. numerous studies have demonstrated that activation of serotonin 5-ht1a or 5-ht1b receptor decreases aggression in male mammals. 1997-12-01 2023-08-12 Not clear
S Hashimoto, T Inoue, T Koyam. Effects of the co-administration of 5-HT1A receptor antagonists with an SSRI in conditioned fear stress-induced freezing behavior. Pharmacology, biochemistry, and behavior. vol 58. issue 2. 1997-12-01. PMID:9300607. these findings suggest that 5-ht1a receptor antagonist, particularly at low doses, enhances the antifreezing effect of citalopram by blocking the autoreceptor-mediated negative feedback mechanisms of the 5-ht neuron. 1997-12-01 2023-08-12 Not clear
S Hashimoto, T Inoue, T Koyam. Effects of the co-administration of 5-HT1A receptor antagonists with an SSRI in conditioned fear stress-induced freezing behavior. Pharmacology, biochemistry, and behavior. vol 58. issue 2. 1997-12-01. PMID:9300607. these experimental results concur with clinical findings that 5-ht1a receptor antagonist pindolol potentiates the effect of 5-ht reuptake inhibitors. 1997-12-01 2023-08-12 Not clear
B J Cao, R J Rodger. Influence of 5-HT1A receptor antagonism on plus-maze behaviour in mice. I. Pindolol enantiomers and pindobind 5-HT1A. Pharmacology, biochemistry, and behavior. vol 58. issue 2. 1997-12-01. PMID:9300623. studies on the behavioural effects of 5-hydroxytryptamine receptor subtype 1a (5-ht1a) antagonists may provide important clues to the precise role of 5-ht1a receptor mechanisms in anxiety. 1997-12-01 2023-08-12 mouse
B J Cao, R J Rodger. Influence of 5-HT1A receptor antagonism on plus-maze behaviour in mice. II. WAY 100635, SDZ 216-525 and NAN-190. Pharmacology, biochemistry, and behavior. vol 58. issue 2. 1997-12-01. PMID:9300624. to understand further the role of 5-hydroxytryptamine receptor subtype 1a (5-ht1a) mechanisms in anxiety, the behavioural effects of 5-ht1a receptor antagonists with different selectivity and intrinsic activity were examined using an ethological version of the murine elevated plus-maze test. 1997-12-01 2023-08-12 mouse
H M Clawges, K M Depree, E M Parker, S G Grabe. Human 5-HT1 receptor subtypes exhibit distinct G protein coupling behaviors in membranes from Sf9 cells. Biochemistry. vol 36. issue 42. 1997-11-20. PMID:9335552. the g protein coupling behavior of four human 5-hydroxytryptamine receptor subtypes (5-ht1a, 5-ht1b, 5-ht1d, and 5-ht1e) has been studied in membranes from sf9 cells expressing the individual receptors. 1997-11-20 2023-08-12 human
K A Grant, G Colombo, G J Gatt. Characterization of the ethanol-like discriminative stimulus effects of 5-HT receptor agonists as a function of ethanol training dose. Psychopharmacology. vol 133. issue 2. 1997-11-20. PMID:9342779. the present studies extend this initial finding to four additional 5-ht agonists with different selectivity for 5-ht1a, 5-ht1b, or 5-ht2c receptors: cgs 12066b (7-trifluoromethyl-4(4-methyl-1-piperazinyl)-pyrrolo[1,2a]quinoxaline maleate), mcpp [1-(3-chlorophenyl)piperazine dihcl], ru 24969 [5-methoxy-3(1,2,3,4-tetrahydro-4-pyridinyl]-1h-indole succinate and 8-oh dpat [(+/-)-8-hydroxy-2-(di-n-propylamino)tetralin hbr]. 1997-11-20 2023-08-12 rat
M B Shaikh, N C De Lanerolle, A Siege. Serotonin 5-HT1A and 5-HT2/1C receptors in the midbrain periaqueductal gray differentially modulate defensive rage behavior elicited from the medial hypothalamus of the cat. Brain research. vol 765. issue 2. 1997-11-13. PMID:9313892. serotonin 5-ht1a and 5-ht2/1c receptors in the midbrain periaqueductal gray differentially modulate defensive rage behavior elicited from the medial hypothalamus of the cat. 1997-11-13 2023-08-12 cat
R Gaggi, R Dall' Olio, M Santangelo, P Roncad. Actions of nimodipine on the serotonergic systems of rat brain. General pharmacology. vol 29. issue 3. 1997-11-10. PMID:9378249. the effects of the serotonin (5-ht) precursor, l-5-hydroxytryptophan (l-5-htp), or the selective 5-ht1a receptor agonist, 8-ohdpat, on behavior or brain 5-ht metabolism or both were evaluated in rats ip pretreated with nimodipine at doses ranging from 0.31 to 40 mg/kg. 1997-11-10 2023-08-12 rat
R Gaggi, R Dall' Olio, M Santangelo, P Roncad. Actions of nimodipine on the serotonergic systems of rat brain. General pharmacology. vol 29. issue 3. 1997-11-10. PMID:9378249. nimodipine antagonized the effects on 5-ht metabolism induced by 8-hydroxy-2-(di-n-propyl-amino)-tetralin through stimulation of 5-ht1a autoreceptors. 1997-11-10 2023-08-12 rat