| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hiroto Nakayama, Sumiyo Umeda, Masashi Nibuya, Takeshi Terao, Koichi Nisijima, Soichiro Nomur. Two cases of mild serotonin toxicity via 5-hydroxytryptamine 1A receptor stimulation. Neuropsychiatric disease and treatment. vol 10. 2014-03-14. PMID:24627634. |
therefore, it could be hypothesized that mild serotonin excess induces side effects through 5-ht1a, and severe serotonin excess induces lethal side effects with hyperthermia through 5-ht2a. |
2014-03-14 |
2023-08-12 |
Not clear |
| Hiroto Nakayama, Sumiyo Umeda, Masashi Nibuya, Takeshi Terao, Koichi Nisijima, Soichiro Nomur. Two cases of mild serotonin toxicity via 5-hydroxytryptamine 1A receptor stimulation. Neuropsychiatric disease and treatment. vol 10. 2014-03-14. PMID:24627634. |
serotonin toxicity via a low dose of paroxetine that is coadministered with perospirone, which acts agonistically on the 5-ht1a receptor and antagonistically on the 5-ht2a receptor, clearly indicated 5-ht1a receptor involvement in mild serotonin toxicity. |
2014-03-14 |
2023-08-12 |
Not clear |
| Hiroto Nakayama, Sumiyo Umeda, Masashi Nibuya, Takeshi Terao, Koichi Nisijima, Soichiro Nomur. Two cases of mild serotonin toxicity via 5-hydroxytryptamine 1A receptor stimulation. Neuropsychiatric disease and treatment. vol 10. 2014-03-14. PMID:24627634. |
careful measures should be adopted to avoid serotonin toxicity following the combined use of ssris and 5-ht1a agonists. |
2014-03-14 |
2023-08-12 |
Not clear |
| María Eugenia Cornide-Petronio, Ramón Anadón, Antón Barreiro-Iglesias, María Celina Rodici. Serotonin 1A receptor (5-HT1A) of the sea lamprey: cDNA cloning and expression in the central nervous system. Brain structure & function. vol 218. issue 5. 2014-03-10. PMID:23052550. |
serotonin 1a receptor (5-ht1a) of the sea lamprey: cdna cloning and expression in the central nervous system. |
2014-03-10 |
2023-08-12 |
Not clear |
| María Eugenia Cornide-Petronio, Ramón Anadón, Antón Barreiro-Iglesias, María Celina Rodici. Serotonin 1A receptor (5-HT1A) of the sea lamprey: cDNA cloning and expression in the central nervous system. Brain structure & function. vol 218. issue 5. 2014-03-10. PMID:23052550. |
one of the major targets of the activity of serotonergic cells is the serotonin 1a receptor (5-ht1a), an ancestral archetypical serotonin receptor. |
2014-03-10 |
2023-08-12 |
Not clear |
| Margarita Valhondo, Isabel Marco, Mar Martín-Fontecha, Henar Vázquez-Villa, José A Ramos, Reinhard Berkels, Thomas Lauterbach, Bellinda Benhamú, María L López-Rodrígue. New serotonin 5-HT1A receptor agonists endowed with antinociceptive activity in vivo. Journal of medicinal chemistry. vol 56. issue 20. 2014-03-10. PMID:24050112. |
new serotonin 5-ht1a receptor agonists endowed with antinociceptive activity in vivo. |
2014-03-10 |
2023-08-12 |
mouse |
| A Dhi. Vortioxetine for the treatment of major depression. Drugs of today (Barcelona, Spain : 1998). vol 49. issue 12. 2014-03-10. PMID:24524096. |
it inhibits the activity of serotonin transporters and is an agonist of serotonin 5-ht1a receptor, partial agonist of 5-ht1b and antagonist of 5-ht3a, 5-ht7 and 5-ht1d receptors. |
2014-03-10 |
2023-08-12 |
Not clear |
| Stal Saurav Shrestha, Jeih-San Liow, Shuiyu Lu, Kimberly Jenko, Robert L Gladding, Per Svenningsson, Cheryl L Morse, Sami S Zoghbi, Victor W Pike, Robert B Inni. (11)C-CUMI-101, a PET radioligand, behaves as a serotonin 1A receptor antagonist and also binds to α(1) adrenoceptors in brain. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. vol 55. issue 1. 2014-03-03. PMID:24385311. |
the pet radioligand (11)c-cumi-101 was previously suggested as a putative agonist radioligand for the serotonin 1a (5-hydroxytryptamine 1a [5-ht1a]) receptor in recombinant cells expressing human 5-ht1a receptor. |
2014-03-03 |
2023-08-12 |
human |
| Silvina L Diaz, Nicolas Narboux-Nême, Sara Trowbridge, Sophie Scotto-Lomassese, Felix B Kleine Borgmann, Sebastian Jessberger, Bruno Giros, Luc Maroteaux, Evan Deneris, Patricia Gaspa. Paradoxical increase in survival of newborn neurons in the dentate gyrus of mice with constitutive depletion of serotonin. The European journal of neuroscience. vol 38. issue 5. 2014-02-26. PMID:23841816. |
overall, our results indicate that constitutive 5-ht depletion does not alter the proliferation of neural precursors in the dg but promotes the survival of newborn cells, an effect which involves activation of postsynaptic 5-ht1a receptors. |
2014-02-26 |
2023-08-12 |
mouse |
| Andrea E Corcoran, Kathryn G Commons, Yuanming Wu, Jeffrey C Smith, Michael B Harris, George B Richerso. Dual effects of 5-HT(1a) receptor activation on breathing in neonatal mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 1. 2014-02-24. PMID:24381267. |
we conclude that 5-ht1a receptor agonists have two competing effects: rapid stimulation of breathing due to excitation of the respiratory network, and delayed inhibition of breathing due to autoreceptor inhibition of 5-ht neurons. |
2014-02-24 |
2023-08-12 |
mouse |
| N P Shugalev, A V Stavrovskaia, N G Iamshchikova, A S Ol'shanskiĭ, E A Kashirin. [Neurotensin influence on painful stress afteractions in rats with neurotoxic damages of serotoninergic structures of brain substantia nigra]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 63. issue 3. 2014-02-21. PMID:24450170. |
administration of serotonin 5-ht1a receptors antagonist p-mppf insert similar influence on aftereffects of painful stimulation. |
2014-02-21 |
2023-08-12 |
rat |
| Yukio Ago, Ryota Araki, Tatsunori Tanaka, Asuka Sasaga, Saki Nishiyama, Kazuhiro Takuma, Toshio Matsud. Role of social encounter-induced activation of prefrontal serotonergic systems in the abnormal behaviors of isolation-reared mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 8. 2014-02-13. PMID:23426384. |
a 5-ht1a receptor agonist, a metabotropic glutamate 2/3 receptor agonist, and a gamma-aminobutyric acid a receptor agonist attenuated isolation-induced aggressive behaviors and encounter-induced hyperactivity, c-fos expression in the prefrontal cortex and dorsal raphe nucleus, and increases in prefrontal 5-ht levels. |
2014-02-13 |
2023-08-12 |
mouse |
| Mauricio P Cunha, Francis L Pazini, Ágatha Oliveira, Daniele G Machado, Ana Lúcia S Rodrigue. Evidence for the involvement of 5-HT1A receptor in the acute antidepressant-like effect of creatine in mice. Brain research bulletin. vol 95. 2014-02-10. PMID:23352985. |
creatine (0.01 mg/kg, sub-effective dose) in combination with sub-effective doses of way100635 (0.1mg/kg, s.c., a 5-ht1a receptor antagonist), 8-oh-dpat (0.1mg/kg, i.p., a 5-ht1a receptor agonist) or selective serotonin reuptake inhibitors fluoxetine (5mg/kg, p.o. |
2014-02-10 |
2023-08-12 |
mouse |
| Naohisa Tsujino, Takahiro Nemoto, Keiko Morita, Naoyuki Katagiri, Shinya Ito, Masafumi Mizun. Long-term Efficacy and Tolerability of Perospirone for Young Help-seeking People at Clinical High Risk: a Preliminary Open Trial. Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology. vol 11. issue 3. 2014-01-27. PMID:24465249. |
we investigated whether administration of perospirone, a combined serotonin (5-ht)/dopamine antagonist and 5-ht1a receptor agonist, could alleviate prodromal symptoms and be well tolerated by clinical high risk patients. |
2014-01-27 |
2023-08-12 |
Not clear |
| Morteza Zendehdel, Kasra Mokhtarpouriani, Vahab Babapour, Ali Baghbanzadeh, Maryam Pourrahimi, Shahin Hassanpou. The effect of serotonergic system on nociceptin/orphanin FQ induced food intake in chicken. The journal of physiological sciences : JPS. vol 63. issue 4. 2014-01-23. PMID:23615894. |
the present study was designed to examine the effects of intracerebroventricular injection of para-chlorophenylalanine (pcpa) (cerebral serotonin depletive), fluoxetine (selective serotonin reuptake inhibitor), 8-oh-dpat (5-ht1a autoreceptor agonist) and sb 242084 (5-ht2c receptor antagonist) on nociceptin/orphanin fq (n/ofq) induced feeding response in chickens. |
2014-01-23 |
2023-08-12 |
chicken |
| S Body, T H C Cheung, L Valencia-Torres, C M Olarte-Sánchez, K C F Fone, C M Bradshaw, E Szabad. Pharmacological studies of performance on the free-operant psychophysical procedure. Behavioural processes. vol 95. 2014-01-21. PMID:23428704. |
t50 is reduced by acute treatment with 5-hydroxytryptamine (5-ht1a, 5-ht2a) and dopamine (d1-like, d2-like) receptor agonists. |
2014-01-21 |
2023-08-12 |
Not clear |
| Dasiel O Borroto-Escuela, Fidel Corrales, Manuel Narvaez, Julia Oflijan, Luigi F Agnati, Miklós Palkovits, Kjell Fux. Dynamic modulation of FGFR1-5-HT1A heteroreceptor complexes. Agonist treatment enhances participation of FGFR1 and 5-HT1A homodimers and recruitment of β-arrestin2. Biochemical and biophysical research communications. vol 441. issue 2. 2014-01-17. PMID:24157794. |
new findings show that neurotrophic and antidepressant effects of 5-ht in brain can, in part, be mediated by activation of the 5-ht1a receptor protomer in the hippocampal and raphe fgfr1-5-ht1a heteroreceptor complexes enhancing the fgfr1 signaling. |
2014-01-17 |
2023-08-12 |
Not clear |
| Neil A Gray, Matthew S Milak, Christine DeLorenzo, R Todd Ogden, Yung-Yu Huang, J John Mann, Ramin V Parse. Antidepressant treatment reduces serotonin-1A autoreceptor binding in major depressive disorder. Biological psychiatry. vol 74. issue 1. 2014-01-15. PMID:23374637. |
chronic selective serotonin reuptake inhibitor (ssri) administration to rodents desensitizes or downregulates raphe 5-hydroxytryptamine 1a (5-ht1a) autoreceptors. |
2014-01-15 |
2023-08-12 |
Not clear |
| Tomiki Sumiyosh. Possible dose-side effect relationship of antipsychotic drugs: relevance to cognitive function in schizophrenia. Expert review of clinical pharmacology. vol 1. issue 6. 2014-01-14. PMID:24410608. |
serotonin (5-hydroxytryptamine [5-ht]) receptor subtypes, such as the 5-ht1a receptor, are considered to mediate the ability of antipsychotic drugs to enhance cognition. |
2014-01-14 |
2023-08-12 |
Not clear |
| Lea R Medeiros, M Danielle McDonal. Cortisol-mediated downregulation of the serotonin 1A receptor subtype in the Gulf toadfish, Opsanus beta. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. vol 164. issue 4. 2014-01-13. PMID:23360731. |
in both mammals and teleost fish, serotonin stimulates cortisol secretion via the 5-ht1a receptor. |
2014-01-13 |
2023-08-12 |
Not clear |