All Relations between 5-ht receptor 1a and serotonin

Publication Sentence Publish Date Extraction Date Species
Dongjuan Liu, Bing Xiao, Fang Han, Feifei Luo, Enhua Wang, Yuxiu Sh. Changes in 5-HT1A receptor expression in the oculomotor nucleus in a rat model of post-traumatic stress disorder. Journal of molecular neuroscience : MN. vol 49. issue 2. 2013-06-27. PMID:22930314. it has been reported that dysfunction of the neurotransmitter 5-hydroxytryptamine (5-ht) can lead to the instability of the internal environment in response to stress and plays an important role in the pathology of ptsd and that the 5-ht1a receptor (5-ht1ar) is critically involved in regulating mood and anxiety levels. 2013-06-27 2023-08-12 rat
Chao Yu, Jin Liu, Yanfang Chen, Yuedi Tan. 5-HT1A receptor-mediated activation of outward potassium current by serotonin in mouse cultured spiral ganglion neurons. General physiology and biophysics. vol 32. issue 1. 2013-06-20. PMID:23531840. 5-ht1a receptor-mediated activation of outward potassium current by serotonin in mouse cultured spiral ganglion neurons. 2013-06-20 2023-08-12 mouse
Chao Yu, Jin Liu, Yanfang Chen, Yuedi Tan. 5-HT1A receptor-mediated activation of outward potassium current by serotonin in mouse cultured spiral ganglion neurons. General physiology and biophysics. vol 32. issue 1. 2013-06-20. PMID:23531840. application of serotonin caused an increase of outward potassium currents within seconds, whereas treatment with way100635, a selective 5-ht1a receptor antagonist, counteracted the increase effect of serotonin. 2013-06-20 2023-08-12 mouse
Chao Yu, Jin Liu, Yanfang Chen, Yuedi Tan. 5-HT1A receptor-mediated activation of outward potassium current by serotonin in mouse cultured spiral ganglion neurons. General physiology and biophysics. vol 32. issue 1. 2013-06-20. PMID:23531840. these results suggest that serotonin increases outward potassium currents in cultured spiral ganglion neurons through the activation of 5-ht1a receptor. 2013-06-20 2023-08-12 mouse
Jocelien D A Olivier, Christiaan H Vinkers, Berend Olivie. The role of the serotonergic and GABA system in translational approaches in drug discovery for anxiety disorders. Frontiers in pharmacology. vol 4. 2013-06-20. PMID:23781201. in this review, we illustrate the complex interplay between genes and environment in anxiety processes by reviewing preclinical and clinical studies on the serotonin transporter (5-htt), 5-ht1a receptor, 5-ht2 receptor, and gabaa receptor. 2013-06-20 2023-08-12 human
Ashley Martinez, Andrey Finegersh, Dara M Cannon, Irene Dustin, Alison Nugent, Peter Herscovitch, William H Theodor. The 5-HT1A receptor and 5-HT transporter in temporal lobe epilepsy. Neurology. vol 80. issue 16. 2013-06-11. PMID:23516322. the 5-ht1a receptor and 5-ht transporter in temporal lobe epilepsy. 2013-06-11 2023-08-12 Not clear
Ashley Martinez, Andrey Finegersh, Dara M Cannon, Irene Dustin, Alison Nugent, Peter Herscovitch, William H Theodor. The 5-HT1A receptor and 5-HT transporter in temporal lobe epilepsy. Neurology. vol 80. issue 16. 2013-06-11. PMID:23516322. to study 5-ht transport and 5-ht1a receptors in temporal lobe epilepsy (tle) and depression. 2013-06-11 2023-08-12 Not clear
Ahmad H Alkhatib, Anna Dvorkin-Gheva, Henry Szechtma. Quinpirole and 8-OH-DPAT induce compulsive checking behavior in male rats by acting on different functional parts of an OCD neurocircuit. Behavioural pharmacology. vol 24. issue 1. 2013-06-10. PMID:23249525. this study investigated whether the serotonin 5-ht1a receptor agonist 8-hydroxy-2-(di-n-propylamino) tetralin (8-oh-dpat) can induce compulsive checking in a large open field, as does the dopamine d2/d3 receptor agonist quinpirole. 2013-06-10 2023-08-12 rat
Victoria S Dalton, Mathieu Verdurand, Adam Walker, Deborah M Hodgson, Katerina Zavitsano. Synergistic Effect between Maternal Infection and Adolescent Cannabinoid Exposure on Serotonin 5HT1A Receptor Binding in the Hippocampus: Testing the "Two Hit" Hypothesis for the Development of Schizophrenia. ISRN psychiatry. vol 2012. 2013-06-06. PMID:23738203. synergistic effect between maternal infection and adolescent cannabinoid exposure on serotonin 5ht1a receptor binding in the hippocampus: testing the "two hit" hypothesis for the development of schizophrenia. 2013-06-06 2023-08-12 rat
Victoria S Dalton, Mathieu Verdurand, Adam Walker, Deborah M Hodgson, Katerina Zavitsano. Synergistic Effect between Maternal Infection and Adolescent Cannabinoid Exposure on Serotonin 5HT1A Receptor Binding in the Hippocampus: Testing the "Two Hit" Hypothesis for the Development of Schizophrenia. ISRN psychiatry. vol 2012. 2013-06-06. PMID:23738203. we combined these factors in an animal model and looked at their effects, alone and in combination, on serotonin 5ht1a receptor binding (5ht1ar) binding longitudinally from late adolescence to adulthood. 2013-06-06 2023-08-12 rat
Florence Cotel, Richard Exley, Stephanie J Cragg, Jean-François Perrie. Serotonin spillover onto the axon initial segment of motoneurons induces central fatigue by inhibiting action potential initiation. Proceedings of the National Academy of Sciences of the United States of America. vol 110. issue 12. 2013-05-23. PMID:23487756. we tested it by measuring the level of extracellular 5-ht with cyclic voltammetry and found that prolonged stimulations of the raphe-spinal pathway increased the level of 5-ht to a concentration sufficient to activate 5-ht1a receptors. 2013-05-23 2023-08-12 Not clear
Kathleen Scullion, Jeffery A Boychuk, Glenn R Yamakawa, Justin T G Rodych, Stan T Nakanishi, Angela Seto, Victoria M Smith, Ryan W McCarthy, Patrick J Whelan, Michael C Antle, Quentin J Pittman, G Campbell Teske. Serotonin 1A receptors alter expression of movement representations. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 11. 2013-05-06. PMID:23486969. in rats, electrical stimulation of the dorsal raphe lowered movement thresholds and this effect could be blocked by direct cortical application of the 5-ht1a antagonist way-100135, indicating that serotonin is primarily acting through the 5-ht1a receptor. 2013-05-06 2023-08-12 mouse
Kathleen Scullion, Jeffery A Boychuk, Glenn R Yamakawa, Justin T G Rodych, Stan T Nakanishi, Angela Seto, Victoria M Smith, Ryan W McCarthy, Patrick J Whelan, Michael C Antle, Quentin J Pittman, G Campbell Teske. Serotonin 1A receptors alter expression of movement representations. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 11. 2013-05-06. PMID:23486969. together our results demonstrate that serotonin, acting through 5-ht1a receptors, plays an excitatory role in forelimb motor map expression. 2013-05-06 2023-08-12 mouse
Wenjun Zhou, Ligong Chen, Jodi Paul, Sufen Yang, Fuzeng Li, Karen Sampson, Jim R Woodgett, Jean Martin Beaulieu, Karen L Gamble, Xiaohua L. The effects of glycogen synthase kinase-3beta in serotonin neurons. PloS one. vol 7. issue 8. 2013-05-01. PMID:22912839. compared to littermate wild type mice, sngsk3β-ko mice had a reduced response to the 5-ht1b receptor agonist anpirtoline in the regulation of serotonergic neuron firing, camp production, and serotonin release, whereas these animals displayed a normal response to the 5-ht1a receptor agonist 8-oh-dpat. 2013-05-01 2023-08-12 mouse
Pau Celada, M Victoria Puig, Francesc Artiga. Serotonin modulation of cortical neurons and networks. Frontiers in integrative neuroscience. vol 7. 2013-04-30. PMID:23626526. 5-ht and selective receptor agonists modulate the excitability of cortical neurons and their discharge rate through the activation of several receptor subtypes, of which the 5-ht1a, 5-ht1b, 5-ht2a, and 5-ht3 subtypes play a major role. 2013-04-30 2023-08-12 Not clear
Pau Celada, M Victoria Puig, Francesc Artiga. Serotonin modulation of cortical neurons and networks. Frontiers in integrative neuroscience. vol 7. 2013-04-30. PMID:23626526. 5-ht can also stimulate excitatory (5-ht2a and 5-ht3) and inhibitory (5-ht1a) receptors in gaba interneurons to modulate synaptic gaba inputs onto pyramidal neurons. 2013-04-30 2023-08-12 Not clear
Eduardo A Pineda, Julie G Hensler, Raman Sankar, Don Shin, Teresa F Burke, Andréy M Mazarat. Interleukin-1β causes fluoxetine resistance in an animal model of epilepsy-associated depression. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. vol 9. issue 2. 2013-04-29. PMID:22427156. in post-se rats, depression-like impairments included behavioral deficits indicative of hopelessness and anhedonia; the hyperactivity of the hypothalamo-pituitary-adrenocortical axis; the diminished serotonin output from raphe nucleus; and the upregulation of presynaptic serotonin 1-a (5-ht1a) receptors. 2013-04-29 2023-08-12 rat
Lara Costa, Michela Spatuzza, Simona D'Antoni, Carmela M Bonaccorso, Chiara Trovato, Sebastiano A Musumeci, Marcello Leopoldo, Enza Lacivita, Maria V Catania, Lucia Cirann. Activation of 5-HT7 serotonin receptors reverses metabotropic glutamate receptor-mediated synaptic plasticity in wild-type and Fmr1 knockout mice, a model of Fragile X syndrome. Biological psychiatry. vol 72. issue 11. 2013-04-23. PMID:22817866. the neurotransmitter serotonin (5-ht) modulates hippocampal-dependent learning through serotonin 1a (5-ht1a) and serotonin 7 (5-ht7) receptors; the underlying mechanisms are unknown. 2013-04-23 2023-08-12 mouse
Gyorgy Bagdy, Gabriella Juhasz, Xenia Gond. A new clinical evidence-based gene-environment interaction model of depression. Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology. vol 14. issue 4. 2013-04-12. PMID:23269207. in the newmood cohort polymorphisms of the genes of the serotonin transporter, 5-ht1a, 5-ht1b and 5-ht2a and endocannabinoid cb1 receptors, tryptophan hydroxylase, creb1, bdnf and girk provide evidence for the involvement of these genes in the development of depression. 2013-04-12 2023-08-12 human
Peter Pregel. Single nucleotide polymorphisms and suicidal behaviour. Psychiatria Danubina. vol 24 Suppl 1. 2013-04-10. PMID:22945190. beside 5-ht1a and other serotonin receptors most studied are the serotonin transporter 5' functional promoter variant, and monoamine oxidase a and the tryptophan-hydroxylase 1 and 2 (tph) polymorphisms. 2013-04-10 2023-08-12 human