| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Joanna Dabrowska, Przemyslaw Nowak, Ryszard Bru. Reactivity of 5-HT1A receptor in adult rats after neonatal noradrenergic neurons' lesion--implications for antidepressant-like action. Brain research. vol 1239. 2010-01-12. PMID:18789911. |
during a microdialysis study of anaesthetized rats, the 5-ht1a receptor agonist, r-(+)-8-oh-dpat (0.1 mg/kg), decreased 5-ht release in the medial prefrontal cortex of control rats but this effect was significantly attenuated in dsp-4-treated animals (10-12 weeks old). |
2010-01-12 |
2023-08-12 |
rat |
| Theodore A Slotkin, Nicola Wrench, Ian T Ryde, T Leon Lassiter, Edward D Levin, Frederic J Seidle. Neonatal parathion exposure disrupts serotonin and dopamine synaptic function in rat brain regions: modulation by a high-fat diet in adulthood. Neurotoxicology and teratology. vol 31. issue 6. 2010-01-07. PMID:19616088. |
in addition, we monitored 5ht1a and 5ht2 receptor binding and the concentration of 5ht presynaptic transporters. |
2010-01-07 |
2023-08-12 |
rat |
| Nina K Popova, Vladimir S Naumenko, Marina A Tibeikina, Alexander V Kuliko. Serotonin transporter, 5-HT1A receptor, and behavior in DBA/2J mice in comparison with four inbred mouse strains. Journal of neuroscience research. vol 87. issue 16. 2010-01-05. PMID:19533737. |
serotonin transporter, 5-ht1a receptor, and behavior in dba/2j mice in comparison with four inbred mouse strains. |
2010-01-05 |
2023-08-12 |
mouse |
| Benoit Labonte, Francis Rodriguez Bambico, Gabriella Gobb. Potentiation of excitatory serotonergic responses by MK-801 in the medial prefrontal cortex. Naunyn-Schmiedeberg's archives of pharmacology. vol 380. issue 5. 2009-12-29. PMID:19727675. |
the 5-ht2a/2c antagonist ritanserin and the 5-ht1a antagonist way100635 were used to block 5-ht responses. |
2009-12-29 |
2023-08-12 |
rat |
| Susan A Brunelli, Jessica A Aviles, Kimberly S Gannon, Aron Branscomb, Sharon Shacha. PRX-00023, a selective serotonin 1A receptor agonist, reduces ultrasonic vocalizations in infant rats bred for high infantile anxiety. Pharmacology, biochemistry, and behavior. vol 94. issue 1. 2009-12-17. PMID:19576924. |
in this study, rates of usv in high line infants (pups: postnatal day 11+/-1) were compared to those of randomly-bred controls in response to epix compound prx-00023, a unique serotonin (5-ht) agonist, acting exclusively at the 5-ht1a receptor, or buspirone, a nonspecific 5ht1a agonist. |
2009-12-17 |
2023-08-12 |
rat |
| Paul T Franci. Biochemical and pathological correlates of cognitive and behavioural change in DLB/PDD. Journal of neurology. vol 256 Suppl 3. 2009-12-11. PMID:19711117. |
in contrast to previous studies of ad, our results indicate that there is no association between depression and the 5-ht transporter, while there was a significant increase in the number of 5-ht1a receptors in those dlb/pdd patients with depression. |
2009-12-11 |
2023-08-12 |
Not clear |
| Joshua Greene, Mounira Banasr, Boyoung Lee, Jennifer Warner-Schmidt, Ronald S Duma. Vascular endothelial growth factor signaling is required for the behavioral actions of antidepressant treatment: pharmacological and cellular characterization. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 34. issue 11. 2009-12-07. PMID:19553916. |
first, by determining the requirement for vegf in the actions of a 5-ht selective reuptake inhibitor (ssri), fluoxetine in behavioral models of depression/antidepressant response; and second, by examining the role of the 5-ht1a receptor subtype in the regulation of vegf, and the cellular localization of antidepressant regulation of vegf expression. |
2009-12-07 |
2023-08-12 |
rat |
| Takashi Iwai, Yohei Hayashi, Saori Narita, Yuko Kasuya, Kazushi Jin, Mamiko Tsugane, Jun-Ichiro Ok. Antidepressant-like effects of glucagon-like peptide-2 in mice occur via monoamine pathways. Behavioural brain research. vol 204. issue 1. 2009-12-01. PMID:19539656. |
these effects were inhibited by pretreatment with metergoline (an antagonist of non-specific 5-ht receptors), parachlorophenylalanine (an inhibitor of 5-ht synthase), nan-190 (an antagonist of 5-ht1a receptors), yohimbine hydrochloride (an antagonist of alpha2 adrenoceptors), atenolol (an antagonist of beta1 receptors), and raclopride (an antagonist of d2 receptors), but not prazosin (an antagonist of alpha1 adrenoceptors), ici118551 (an antagonist of beta2 adrenoceptors), and sch23394 (an antagonist of d1 receptors). |
2009-12-01 |
2023-08-12 |
mouse |
| Hiroto Miwa, A Nagahara, K Tominaga, T Yokoyama, Y Sawada, K Inoue, Kiyoshi Ashida, T Fukuchi, M Hojo, H Yamashita, T Tomita, K Hori, T Oshim. Efficacy of the 5-HT1A agonist tandospirone citrate in improving symptoms of patients with functional dyspepsia: a randomized controlled trial. The American journal of gastroenterology. vol 104. issue 11. 2009-12-01. PMID:19638966. |
the aim of this study was to examine the efficacy of tandospirone citrate, a new partial agonist of the 5-hydroxytryptamine 1a (5-ht1a) receptor, in improving the symptoms of patients with fd. |
2009-12-01 |
2023-08-12 |
Not clear |
| F Fiorino, B Severino, F De Angelis, E Perissutti, E Magli, F Frecentese, A Esposito, P Massarelli, C Nencini, B Viti, V Santagada, G Caliend. Synthesis and in vitro pharmacological evaluation of a new series of 5-HT1A 5-HT2A and 5-HT2C receptor ligands containing a norbornene nucleus. Die Pharmazie. vol 64. issue 9. 2009-11-25. PMID:19827295. |
a series of 4-substituted piperazine derivatives bearing a norbornene nucleus have been prepared and their affinity for serotonin 5-ht1a, 5-ht2a and 5-ht2c receptors has been evaluated. |
2009-11-25 |
2023-08-12 |
Not clear |
| Eugene Lin, Po See Chen, Hui Hua Chang, Po-Wu Gean, Hsin Chun Tsai, Yen Kuang Yang, Ru-Band L. Interaction of serotonin-related genes affects short-term antidepressant response in major depressive disorder. Progress in neuro-psychopharmacology & biological psychiatry. vol 33. issue 7. 2009-11-17. PMID:19560507. |
four serotonin-related genes including guanine nucleotide binding protein beta polypeptide 3 (gnb3), 5-hydroxytryptamine receptor 1a (htr1a; serotonin receptor 1a), 5-hydroxytryptamine receptor 2a (htr2a; serotonin receptor 2a), and solute carrier family 6 member 4 (slc6a4; serotonin neurotransmitter transporter) have been suggested to be candidate genes for influencing antidepressant treatment outcome. |
2009-11-17 |
2023-08-12 |
Not clear |
| C Gorini, H S Jameson, D Mendelowit. Serotonergic modulation of the trigeminocardiac reflex neurotransmission to cardiac vagal neurons in the nucleus ambiguus. Journal of neurophysiology. vol 102. issue 3. 2009-10-23. PMID:19553488. |
consistent with the hypothesis this pathway is endogenously modulated by 5-ht receptors the 5-ht1a receptor antagonist, way 100635 inhibited, whereas the 5-ht2a/c receptor antagonist, ketanserin facilitated the excitatory neurotransmission to cvns. |
2009-10-23 |
2023-08-12 |
Not clear |
| Elvan Ozal. [The genetics of suicidal behavior]. Turk psikiyatri dergisi = Turkish journal of psychiatry. vol 20. issue 1. 2009-10-06. PMID:19306130. |
the most important candidate genes include the serotonin transporters (serts), tryptophan hydroxylase (tph), some serotonin receptors (5ht1a, 5ht1b, and 5ht2a), catechol-o-methyltransferase (comt), monoamine oxidase-a (mao-a), and tyrosine hydroxylase (th). |
2009-10-06 |
2023-08-12 |
Not clear |
| Santiago Vilar González, Francesc Montañá Puig, Sebastiá Sabater Martí, Ma Victoria Villas Sánchez, Ma del Mar Sevillano Capellán, Manuel Aguayo Marto. [Trazodone: a new selective approach to the treatment of hot flashes induced by androgen deprivation in prostate carcinoma?]. Actas urologicas espanolas. vol 33. issue 6. 2009-10-02. PMID:19711746. |
the use of trazodone, increasing the serotonin concentrations and blocking the 5-ht2a and 5-ht1a receptors, could be viewed as a novel management approach more in line with the physiopathology of hot flashes. |
2009-10-02 |
2023-08-12 |
Not clear |
| Ana Muñoz, Thomas Carlsson, Elisabetta Tronci, Deniz Kirik, Anders Björklund, Manolo Cart. Serotonin neuron-dependent and -independent reduction of dyskinesia by 5-HT1A and 5-HT1B receptor agonists in the rat Parkinson model. Experimental neurology. vol 219. issue 1. 2009-09-25. PMID:19500572. |
serotonin neuron-dependent and -independent reduction of dyskinesia by 5-ht1a and 5-ht1b receptor agonists in the rat parkinson model. |
2009-09-25 |
2023-08-12 |
rat |
| G Kastengren Fröberg, R Lindberg, M Ritter, K Nordlin. Expression of serotonin and its 5-HT1A receptor in canine cutaneous mast cell tumours. Journal of comparative pathology. vol 141. issue 2-3. 2009-09-22. PMID:19446835. |
expression of serotonin and its 5-ht1a receptor in canine cutaneous mast cell tumours. |
2009-09-22 |
2023-08-12 |
Not clear |
| G Kastengren Fröberg, R Lindberg, M Ritter, K Nordlin. Expression of serotonin and its 5-HT1A receptor in canine cutaneous mast cell tumours. Journal of comparative pathology. vol 141. issue 2-3. 2009-09-22. PMID:19446835. |
in the present study, canine cutaneous mast cell tumours (mcts) of patnaik histological grades i-iii were investigated immunohistochemically for expression of 5-ht and its receptor (r) 5-ht1a. |
2009-09-22 |
2023-08-12 |
Not clear |
| G Kastengren Fröberg, R Lindberg, M Ritter, K Nordlin. Expression of serotonin and its 5-HT1A receptor in canine cutaneous mast cell tumours. Journal of comparative pathology. vol 141. issue 2-3. 2009-09-22. PMID:19446835. |
both 5-ht and the 5-ht1a receptor were expressed by non-neoplastic dermal mast cells and neoplastic mast cells. |
2009-09-22 |
2023-08-12 |
Not clear |
| G Kastengren Fröberg, R Lindberg, M Ritter, K Nordlin. Expression of serotonin and its 5-HT1A receptor in canine cutaneous mast cell tumours. Journal of comparative pathology. vol 141. issue 2-3. 2009-09-22. PMID:19446835. |
5-ht and the 5-ht1a receptor may be involved in the differentiation of canine mcts and in the microvascular complications associated with these neoplasms. |
2009-09-22 |
2023-08-12 |
Not clear |
| Dahui Zhou, Gary P Stack, Jennifer Lo, Amedeo A Failli, Deborah A Evrard, Boyd L Harrison, Nicole T Hatzenbuhler, Megan Tran, Susan Croce, Soo Yi, Jeannette Golembieski, Geoffrey A Hornby, Margaret Lai, Qian Lin, Lee E Schechter, Deborah L Smith, Adam D Shilling, Christine Huselton, Paul Mitchell, Chad E Beyer, Terrance H Andre. Synthesis, potency, and in vivo evaluation of 2-piperazin-1-ylquinoline analogues as dual serotonin reuptake inhibitors and serotonin 5-HT1A receptor antagonists. Journal of medicinal chemistry. vol 52. issue 15. 2009-09-21. PMID:19719241. |
synthesis, potency, and in vivo evaluation of 2-piperazin-1-ylquinoline analogues as dual serotonin reuptake inhibitors and serotonin 5-ht1a receptor antagonists. |
2009-09-21 |
2023-08-12 |
Not clear |