| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jussi Hirvonen, Jaana Kajander, Topias Allonen, Vesa Oikonen, Kjell Någren, Jarmo Hietal. Measurement of serotonin 5-HT1A receptor binding using positron emission tomography and [carbonyl-(11)C]WAY-100635-considerations on the validity of cerebellum as a reference region. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 27. issue 1. 2007-09-17. PMID:16685258. |
[carbonyl-(11)c]way-100635 has been used extensively in positron emission tomography (pet) imaging of serotonin 1a receptors (5-ht1a) in vivo in the human brain. |
2007-09-17 |
2023-08-12 |
human |
| Agnès L Auclair, Alexandra Galinier, Joël Besnard, Adrian Newman-Tancredi, Ronan Depoortèr. Putative antipsychotics with pronounced agonism at serotonin 5-HT1A and partial agonist activity at dopamine D2 receptors disrupt basal PPI of the startle reflex in rats. Psychopharmacology. vol 193. issue 1. 2007-09-06. PMID:17393144. |
putative antipsychotics with pronounced agonism at serotonin 5-ht1a and partial agonist activity at dopamine d2 receptors disrupt basal ppi of the startle reflex in rats. |
2007-09-06 |
2023-08-12 |
rat |
| Esther Berrocoso, M Dolores De Benito, Juan A Mic. Role of serotonin 5-HT1A and opioid receptors in the antiallodynic effect of tramadol in the chronic constriction injury model of neuropathic pain in rats. Psychopharmacology. vol 193. issue 1. 2007-09-06. PMID:17393145. |
role of serotonin 5-ht1a and opioid receptors in the antiallodynic effect of tramadol in the chronic constriction injury model of neuropathic pain in rats. |
2007-09-06 |
2023-08-12 |
rat |
| Yong Hoon Ryu, Jeih-San Liow, Sami Zoghbi, Masahiro Fujita, Jerry Collins, Dnyanesh Tipre, Janet Sangare, Jinsoo Hong, Victor W Pike, Robert B Inni. Disulfiram inhibits defluorination of (18)F-FCWAY, reduces bone radioactivity, and enhances visualization of radioligand binding to serotonin 5-HT1A receptors in human brain. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. vol 48. issue 7. 2007-08-27. PMID:17574977. |
disulfiram inhibits defluorination of (18)f-fcway, reduces bone radioactivity, and enhances visualization of radioligand binding to serotonin 5-ht1a receptors in human brain. |
2007-08-27 |
2023-08-12 |
human |
| Yuji Odagaki, Ryoichi Toyoshim. 5-HT1A receptor agonist properties of antipsychotics determined by [35S]GTPgammaS binding in rat hippocampal membranes. Clinical and experimental pharmacology & physiology. vol 34. issue 5-6. 2007-08-15. PMID:17439416. |
5-hydroxytryptamine 1a (5-ht1a) receptors have attracted increasing attention as a promising target for antipsychotic therapy. |
2007-08-15 |
2023-08-12 |
rat |
| Ethan D Clotfelter, Erin P O'Hare, Meredith M McNitt, Russ E Carpenter, Cliff H Summer. Serotonin decreases aggression via 5-HT1A receptors in the fighting fish Betta splendens. Pharmacology, biochemistry, and behavior. vol 87. issue 2. 2007-08-15. PMID:17553555. |
serotonin decreases aggression via 5-ht1a receptors in the fighting fish betta splendens. |
2007-08-15 |
2023-08-12 |
Not clear |
| Ethan D Clotfelter, Erin P O'Hare, Meredith M McNitt, Russ E Carpenter, Cliff H Summer. Serotonin decreases aggression via 5-HT1A receptors in the fighting fish Betta splendens. Pharmacology, biochemistry, and behavior. vol 87. issue 2. 2007-08-15. PMID:17553555. |
acute treatment with 5-ht and with the 5-ht1a receptor agonist 8-oh-dpat both decreased aggressive behavior; however, treatment with the 5-ht1a receptor antagonist way-100635 did not increase aggression. |
2007-08-15 |
2023-08-12 |
Not clear |
| Valérie Kayser, Iskander Elfihri Elfassi, Bertrand Aubel, Maxette Melfort, David Julius, Jay A Gingrich, Michel Hamon, Sylvie Bourgoi. Mechanical, thermal and formalin-induced nociception is differentially altered in 5-HT1A-/-, 5-HT1B-/-, 5-HT2A-/-, 5-HT3A-/- and 5-HTT-/- knock-out male mice. Pain. vol 130. issue 3. 2007-08-09. PMID:17250964. |
pain behaviors of mutants which do not express 5-ht1a, 5-ht1b, 5-ht2a or 5-ht3a receptors, or lacking the 5-ht transporter, compared to paired wild-type mice of the same genetic background, were examined using validated tests based on different sensory modalities. |
2007-08-09 |
2023-08-12 |
mouse |
| Reshma Farooq, Darakhshan J Haleem, M A Halee. Dose related effects of buspirone on serum electrolyte balance, plasma osmolality and systolic blood pressure (SBP) in rats. Pakistan journal of pharmaceutical sciences. vol 20. issue 4. 2007-08-09. PMID:17604252. |
the results are discussed in the context of serotonin receptors (5-ht1a) to be involved in buspirone-induced changes of electrolytes, sbp and plasma osmolality. |
2007-08-09 |
2023-08-12 |
human |
| Dahui Zhou, Nicole T Hatzenbuhler, Jonathan L Gross, Boyd L Harrison, Deborah A Evrard, Michael Chlenov, Jeannette Golembieski, Geoffrey Hornby, Lee E Schechter, Deborah L Smith, Terrance H Andree, Gary P Stac. Novel pyridyl-fused 3-amino chroman derivatives with dual action at serotonin transporter and 5-HT1A receptor. Bioorganic & medicinal chemistry letters. vol 17. issue 11. 2007-08-07. PMID:17407811. |
novel pyridyl-fused 3-amino chroman derivatives with dual action at serotonin transporter and 5-ht1a receptor. |
2007-08-07 |
2023-08-12 |
Not clear |
| Michel Weiss, Pierre Blier, Claude de Montign. Effect of long-term administration of the antidepressant drug milnacipran on serotonergic and noradrenergic neurotransmission in the rat hippocampus. Life sciences. vol 81. issue 2. 2007-08-06. PMID:17568622. |
the sensitivity of neither the extrasynaptic nor that of the postsynaptic 5-ht1a receptors of the pyramidal neurons was altered, as indicated by their unchanged responsiveness to the microiontophoretic application of 5-ht, and by the unchanged effect of the electrical stimulation at low frequency of the ascending 5-ht bundle, respectively. |
2007-08-06 |
2023-08-12 |
rat |
| Manolo Carta, Thomas Carlsson, Deniz Kirik, Anders Björklun. Dopamine released from 5-HT terminals is the cause of L-DOPA-induced dyskinesia in parkinsonian rats. Brain : a journal of neurology. vol 130. issue Pt 7. 2007-07-24. PMID:17452372. |
removal of the serotonin afferents, or dampening of serotonin neuron activity by 5-ht1a and 5-ht1b agonist drugs, resulted in a near-complete block of the l-dopa-induced dyskinesias, suggesting that dysregulated dopamine release from serotonin terminals is the prime trigger of dyskinesia in the rat parkinson's disease model. |
2007-07-24 |
2023-08-12 |
rat |
| Amani Eltayb, Marie-Louise G Wadenberg, Björn Schilström, Torgny H Svensso. Antipsychotic-like effect by combined treatment with citalopram and WAY 100635: involvement of the 5-HT2C receptor. The international journal of neuropsychopharmacology. vol 10. issue 3. 2007-07-20. PMID:16879758. |
we showed that a combination of a high dose of citalopram, a selective serotonin reuptake inhibitor (ssri) and the selective 5-ht1a receptor antagonist way 100635 produces significant catalepsy in rats, similar to apds. |
2007-07-20 |
2023-08-12 |
rat |
| Xiang-Yang Zhang, Fumihiko Yasuno, Sami S Zoghbi, Jeih-San Liow, Jinsoo Hong, Julie A McCarron, Victor W Pike, Robert B Inni. Quantification of serotonin 5-HT1A receptors in humans with [11C](R)-(-)-RWAY: radiometabolite(s) likely confound brain measurements. Synapse (New York, N.Y.). vol 61. issue 7. 2007-07-10. PMID:17415792. |
quantification of serotonin 5-ht1a receptors in humans with [11c](r)-(-)-rway: radiometabolite(s) likely confound brain measurements. |
2007-07-10 |
2023-08-12 |
human |
| Syed Y Abbas, Maria I Nogueira, Efrain C Azmiti. Antagonist-induced increase in 5-HT1A-receptor expression in adult rat hippocampus and cortex. Synapse (New York, N.Y.). vol 61. issue 7. 2007-07-10. PMID:17447257. |
serotonin 1a (5-ht1a) receptor expression in 5-ht and serum-free fetal hippocampal cultures is increased in the presence of a specific 5-ht1a-receptor antagonist n-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-n-(2-pyridinyl) cyclohexane carboxamide (way 100635). |
2007-07-10 |
2023-08-12 |
rat |
| b' Ricard Navin\\xc3\\xa9s, Roc\\xc3\\xado Mart\\xc3\\xadn-Santos, Esther G\\xc3\\xb3mez-Gil, Mar\\xc3\\xada J Mart\\xc3\\xadnez de Osaba, M Luisa Imaz, Crist\\xc3\\xb3bal Gast\\xc3\\xb. Effects of citalopram treatment on hypothermic and hormonal responses to the 5-HT1A receptor agonist buspirone in patients with major depression and therapeutic response. Psychoneuroendocrinology. vol 32. issue 4. 2007-07-03. PMID:17337123.' |
serotonin (5-ht) 5-ht1a receptor seems to play an important role in the pathophysiology of major depression and in the mechanism of action of antidepressants. |
2007-07-03 |
2023-08-12 |
Not clear |
| Arlene D Stark, Shaun Jordan, Kelly A Allers, Robert L Bertekap, Ruoyan Chen, Tanaz Mistry Kannan, Thaddeus F Molski, Frank D Yocca, Trevor Sharp, Tetsuro Kikuchi, Kevin D Burri. Interaction of the novel antipsychotic aripiprazole with 5-HT1A and 5-HT 2A receptors: functional receptor-binding and in vivo electrophysiological studies. Psychopharmacology. vol 190. issue 3. 2007-06-18. PMID:17242925. |
interaction of the novel antipsychotic aripiprazole with 5-ht1a and 5-ht 2a receptors: functional receptor-binding and in vivo electrophysiological studies. |
2007-06-18 |
2023-08-12 |
Not clear |
| Ursula F Bailer, Guido K Frank, Shannan E Henry, Julie C Price, Carolyn C Meltzer, Chester A Mathis, Angela Wagner, Laura Thornton, Jessica Hoge, Scott K Ziolko, Carl R Becker, Claire W McConaha, Walter H Kay. Exaggerated 5-HT1A but normal 5-HT2A receptor activity in individuals ill with anorexia nervosa. Biological psychiatry. vol 61. issue 9. 2007-06-06. PMID:17241616. |
because little is known about 5-ht receptor function in an, positron emission tomography (pet) imaging with 5-ht receptor-specific radioligands was used to characterize 5-ht1a and 5-ht2a receptors. |
2007-06-06 |
2023-08-12 |
Not clear |
| Janaina Menezes Zanoveli, Regina Lúcia Nogueira, Hélio Zangross. Enhanced reactivity of 5-HT1A receptors in the rat dorsal periaqueductal gray matter after chronic treatment with fluoxetine and sertraline: evidence from the elevated T-maze. Neuropharmacology. vol 52. issue 4. 2007-06-01. PMID:17313964. |
behavioral evidence indicates that sensitization of 5-ht1a and 5-ht2a receptors in the dorsal periaqueductal gray (dpag) may underlie the therapeutic effect of serotonin reuptake inhibitors (sris) in panic disorder. |
2007-06-01 |
2023-08-12 |
rat |
| Takayoshi Mamiya, Mitsuo Kise, Keiko Morikawa, Hiromichi Aoto, Makoto Ukai, Yukihiro Nod. Effects of pre-germinated brown rice on depression-like behavior in mice. Pharmacology, biochemistry, and behavior. vol 86. issue 1. 2007-05-22. PMID:17258802. |
additionally, we could not detect any differences in the expression of the 5-ht1a receptor and the 5-ht transporter in the frontal cortex of the three groups. |
2007-05-22 |
2023-08-12 |
mouse |