All Relations between 5-ht receptor 1a and serotonin

Publication Sentence Publish Date Extraction Date Species
Morten Grunnet, Thomas Jespersen, Jean-François Perrie. 5-HT1A receptors modulate small-conductance Ca2+-activated K+ channels. Journal of neuroscience research. vol 78. issue 6. 2005-03-07. PMID:15521063. here we tested the ability of serotonin (5-ht) to modulate the activity of sk channels by coexpressing 5-ht1a receptors with different subtypes of sk channels (sk1, sk2, and sk3) in xenopus laevis oocytes. 2005-03-07 2023-08-12 xenopus_laevis
B Aouizerate, C Martin-Guehl, J Tigno. [Neurobiology and pharmacotherapy of social phobia]. L'Encephale. vol 30. issue 4. 2005-03-01. PMID:15538306. although no abnormality in platelet serotonin transporter density has been found, patients with social phobia appear to show an enhanced sensitivity of both post-synaptic 5ht1a and 5ht2 serotonin receptor subtypes, as reflected by increased anxiety and hormonal responses to serotoninergic probes. 2005-03-01 2023-08-12 human
E M Jagoda, J J Vaquero, J Seidel, M V Green, W C Eckelma. Experiment assessment of mass effects in the rat: implications for small animal PET imaging. Nuclear medicine and biology. vol 31. issue 6. 2005-02-25. PMID:15246368. because of the importance of the mass injected for small animal pet imaging, we experimentally compared high and low mass preparations using ex vivo biodistribution and phosphorimaging of three compounds: 2-fluoro-2-deoxyglucose (fdg), 6-fluoro-l-metatyrosine (fmt) and one receptor-directed compound, the serotonin 5ht1a receptor ligand, trans-4-fluoro-n-[2-[4-(2-methoxylphenyl) piperazino]ethyl]-n-(2-pyridyl) cyclohexane- carboxamide (fcway). 2005-02-25 2023-08-12 mouse
Nasser Haddjeri, Céline Faure, Guillaume Lucas, Ouissame Mnie-Filali, Guy Chouvet, Bernadette Astier, Bernard Renaud, Pierre Blier, Guy Debonne. In-vivo modulation of central 5-hydroxytryptamine (5-HT1A) receptor-mediated responses by the cholinergic system. The international journal of neuropsychopharmacology. vol 7. issue 4. 2005-02-24. PMID:15140278. in-vivo modulation of central 5-hydroxytryptamine (5-ht1a) receptor-mediated responses by the cholinergic system. 2005-02-24 2023-08-12 rat
Nasser Haddjeri, Céline Faure, Guillaume Lucas, Ouissame Mnie-Filali, Guy Chouvet, Bernadette Astier, Bernard Renaud, Pierre Blier, Guy Debonne. In-vivo modulation of central 5-hydroxytryptamine (5-HT1A) receptor-mediated responses by the cholinergic system. The international journal of neuropsychopharmacology. vol 7. issue 4. 2005-02-24. PMID:15140278. on the spontaneous firing activity of 5-ht neurons, suggesting that atropine could induce an attenuation of somatodendritic 5-ht1a autoreceptors responsiveness. 2005-02-24 2023-08-12 rat
Yung-Yu Huang, Cristina Battistuzzi, Maria A Oquendo, Jill Harkavy-Friedman, Laurence Greenhill, Gil Zalsman, Beth Brodsky, Victoria Arango, David A Brent, J John Man. Human 5-HT1A receptor C(-1019)G polymorphism and psychopathology. The international journal of neuropsychopharmacology. vol 7. issue 4. 2005-02-24. PMID:15469667. dysfunction of the serotonin (5-ht1a) receptor (5-htr1a) has been implicated in mood disorders, anxiety disorders, psychosis and the action of antidepressants. 2005-02-24 2023-08-12 human
Yung-Yu Huang, Cristina Battistuzzi, Maria A Oquendo, Jill Harkavy-Friedman, Laurence Greenhill, Gil Zalsman, Beth Brodsky, Victoria Arango, David A Brent, J John Man. Human 5-HT1A receptor C(-1019)G polymorphism and psychopathology. The international journal of neuropsychopharmacology. vol 7. issue 4. 2005-02-24. PMID:15469667. 5-ht1a receptor binding was assayed in post-mortem prefrontal cortex using [3h]8-oh-dpat, and specific binding determined by 1 microm 5-ht. 2005-02-24 2023-08-12 human
Klaus Peter Lesch, Lise Gutknech. Focus on The 5-HT1A receptor: emerging role of a gene regulatory variant in psychopathology and pharmacogenetics. The international journal of neuropsychopharmacology. vol 7. issue 4. 2005-02-24. PMID:15683551. (2004) make a strong argument for contribution of a functional 5-ht1a receptor gene variant in the pharmacogenetics of antidepressant treatment with prototypic tricyclics and selective serotonin reuptake inhibitors (ssris). 2005-02-24 2023-08-12 Not clear
Geoffrey Andrew Lambert, Cathy Donaldson, Karen Lisa Hoskin, Peter Michael Boers, Alessandro Stefano Zagam. Dilatation induced by 5-HT in the middle meningeal artery of the anaesthetised cat. Naunyn-Schmiedeberg's archives of pharmacology. vol 369. issue 6. 2005-02-22. PMID:15197536. dose-response curves of vascular resistance changes to intravenous injection of 5-ht were not significantly affected by way100635 (5-ht1a antagonist), gr127935 (5-ht(1b/1d) antagonist), methiothepin (5-ht2c and 5-ht7 antagonist), ketanserin (5-ht2a antagonist), sb203186 (5-ht4 antagonist) or cervical sympathectomy, but were blocked by the 5-ht(3/4) antagonist tropisetron, the 5-ht3 antagonist ondansetron, the ganglion-blocking drug hexamethonium and by vagotomy. 2005-02-22 2023-08-12 cat
Mitsuko Okada, David Goldman, Markku Linnoila, Nakao Iwata, Norio Ozaki, John K Northu. Comparison of G-protein selectivity of human 5-HT2C and 5-HT1A receptors. Annals of the New York Academy of Sciences. vol 1025. 2005-02-18. PMID:15542764. when the two 5-ht receptors were expressed in cells also expressing g proteins, both 5-ht2c and 5-ht1a receptors appear to activate galphai2 in preference to galphaq. 2005-02-18 2023-08-12 human
Hao-Jun You, Francis C Colpaert, Lars Arendt-Nielse. The novel analgesic and high-efficacy 5-HT1A receptor agonist F 13640 inhibits nociceptive responses, wind-up, and after-discharges in spinal neurons and withdrawal reflexes. Experimental neurology. vol 191. issue 1. 2005-02-18. PMID:15589524. for the first time, 5-ht1a receptors are clearly proved to be involved in the progressive wind-up to 3-hz frequency of electrical stimulation as well as after-discharges of sensory input of dh wdr neurons, and simultaneously recorded motor output of spinal reflexes to 20-hz frequency of electrical stimulation; this suggests that serotonin, through 5-ht1a receptors, exerts an inhibitory role in the control of obstinate pathological pain. 2005-02-18 2023-08-12 rat
Kenneth M Boy, Michael Dee, Joseph Yevich, John Torrente, Qi Gao, Lawrence Iben, Arlene Stark, Ronald J Mattso. Ligand conformation has a definitive effect on 5-HT1A and serotonin reuptake affinity. Bioorganic & medicinal chemistry letters. vol 14. issue 17. 2005-02-09. PMID:15357973. ligand conformation has a definitive effect on 5-ht1a and serotonin reuptake affinity. 2005-02-09 2023-08-12 Not clear
J P Voigt, B Nwaiser, A Rex, C Mayer, H Fin. Effect of 5-HT1A receptor activation on hypothalamic glucose. Pharmacological research. vol 50. issue 3. 2005-02-08. PMID:15225681. the data demonstrate furthermore 8-oh-dpat-induced changes of hypothalamic glucose level, implicating 5-ht1a receptors being involved not only in the control of hypothalamic 5-ht as shown before, but also in the control of hypothalamic glucose. 2005-02-08 2023-08-12 rat
Tai-Jui Chen, Younger W-Y Yu, Chen-Jee Hong, Ming-Chao Chen, Shih-Jen Tsa. Association analysis for the C-1019G promoter variant of the 5-HT1A receptor gene with auditory evoked potentials in major depression. Neuropsychobiology. vol 50. issue 4. 2005-01-31. PMID:15539859. the serotonin 1a (5-ht1a) receptor gene is a strong candidate for n1 and p2 components of the aeps because 5-ht1a receptor regulates the firing of serotonergic neurons. 2005-01-31 2023-08-12 Not clear
Kevin G Shields, Peter J Goadsb. Propranolol modulates trigeminovascular responses in thalamic ventroposteromedial nucleus: a role in migraine? Brain : a journal of neurology. vol 128. issue Pt 1. 2005-01-28. PMID:15574468. serotonin (5-ht) receptor antagonism did not contribute to propranolol's action since the 5-ht1a receptor antagonist, (s)-way 100135 (p = 0.2), and the 5-ht1b/1d receptor antagonist, gr127935 (p = 0.6), did not affect l-glutamate-evoked neuronal firing. 2005-01-28 2023-08-12 rat
I Ceglia, S Acconcia, C Fracasso, M Colovic, S Caccia, R W Invernizz. Effects of chronic treatment with escitalopram or citalopram on extracellular 5-HT in the prefrontal cortex of rats: role of 5-HT1A receptors. British journal of pharmacology. vol 142. issue 3. 2005-01-25. PMID:15148253. effects of chronic treatment with escitalopram or citalopram on extracellular 5-ht in the prefrontal cortex of rats: role of 5-ht1a receptors. 2005-01-25 2023-08-12 rat
I Ceglia, S Acconcia, C Fracasso, M Colovic, S Caccia, R W Invernizz. Effects of chronic treatment with escitalopram or citalopram on extracellular 5-HT in the prefrontal cortex of rats: role of 5-HT1A receptors. British journal of pharmacology. vol 142. issue 3. 2005-01-25. PMID:15148253. 1 microdialysis was used to study the acute and chronic effects of escitalopram (s-citalopram; escit) and chronic citalopram (cit), together with the 5-ht1a receptor antagonist way100,635 (n-[2-[methoxyphenyl)-1-piperazinyl]ethyl]-n-(2-pyridinyl) cyclohexane carboxamide trihydrochloride) and the 5-ht1a receptor agonist 8-hydroxy-2-(di-n-propylamino)tetralin (8-oh-dpat), on extracellular 5-hydroxytryptamine (5-ht) levels in the rat prefrontal cortex. 2005-01-25 2023-08-12 rat
I Ceglia, S Acconcia, C Fracasso, M Colovic, S Caccia, R W Invernizz. Effects of chronic treatment with escitalopram or citalopram on extracellular 5-HT in the prefrontal cortex of rats: role of 5-HT1A receptors. British journal of pharmacology. vol 142. issue 3. 2005-01-25. PMID:15148253. 6 this series of experiments led to the conclusion that chronic treatment with escit desensitizes the 5-ht1a receptors, regulating the release of 5-ht in the prefrontal cortex and enhances the effect of the drug on extracellular 5-ht. 2005-01-25 2023-08-12 rat
M Victoria Puig, Noemí Santana, Pau Celada, Guadalupe Mengod, Francesc Artiga. In vivo excitation of GABA interneurons in the medial prefrontal cortex through 5-HT3 receptors. Cerebral cortex (New York, N.Y. : 1991). vol 14. issue 12. 2005-01-25. PMID:15166106. serotonin (5-hydroxytryptamine, 5-ht) controls pyramidal cell activity in prefrontal cortex (pfc) through various receptors, in particular, 5-ht1a and 5-ht2a receptors. 2005-01-25 2023-08-12 rat
Yo Muraki, Akihiro Yamanaka, Natsuko Tsujino, Thomas S Kilduff, Katsutoshi Goto, Takeshi Sakura. Serotonergic regulation of the orexin/hypocretin neurons through the 5-HT1A receptor. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 32. 2005-01-25. PMID:15306649. a 5-ht1a receptor agonist, 8-hydroxy-2-(dl-n-propyl-amino)tetralin, also evoked hyperpolarization on orexin neurons with potency comparable with 5-ht. 2005-01-25 2023-08-12 mouse