All Relations between 5-ht receptor 1a and serotonin

Publication Sentence Publish Date Extraction Date Species
Yukio Ago, Yutaka Koyama, Akemichi Baba, Toshio Matsud. Regulation by 5-HT1A receptors of the in vivo release of 5-HT and DA in mouse frontal cortex. Neuropharmacology. vol 45. issue 8. 2004-02-11. PMID:14614948. regulation by 5-ht1a receptors of the in vivo release of 5-ht and da in mouse frontal cortex. 2004-02-11 2023-08-12 mouse
Yukio Ago, Yutaka Koyama, Akemichi Baba, Toshio Matsud. Regulation by 5-HT1A receptors of the in vivo release of 5-HT and DA in mouse frontal cortex. Neuropharmacology. vol 45. issue 8. 2004-02-11. PMID:14614948. oral mkc-242 and 8-oh-dpat, selective 5-ht1a receptor agonists, decreased cortical 5-ht release at low and high doses, while the receptor agonists increased cortical da release only at a high dose. 2004-02-11 2023-08-12 mouse
Yukio Ago, Yutaka Koyama, Akemichi Baba, Toshio Matsud. Regulation by 5-HT1A receptors of the in vivo release of 5-HT and DA in mouse frontal cortex. Neuropharmacology. vol 45. issue 8. 2004-02-11. PMID:14614948. local application of the selective 5-ht1a receptor antagonist, way100635, via a dialysis probe, antagonized oral mkc-242-induced increase in cortical da release, but did not affect the decrease in cortical 5-ht release. 2004-02-11 2023-08-12 mouse
Yukio Ago, Yutaka Koyama, Akemichi Baba, Toshio Matsud. Regulation by 5-HT1A receptors of the in vivo release of 5-HT and DA in mouse frontal cortex. Neuropharmacology. vol 45. issue 8. 2004-02-11. PMID:14614948. these results suggest that 5-ht release and da release in the frontal cortex of mice are regulated by pre- and postsynaptic 5-ht1a receptors, respectively, and that the presynaptic 5-ht1a receptor-mediated response is more sensitive to inhibition by way100635 than the postsynaptic 5-ht1a receptor-mediated response in mice. 2004-02-11 2023-08-12 mouse
E Lorenc-Koci, J Wardas, G D Bartoszyk, S Wolfart. Contribution of the serotonin 5-HT1A receptor agonism of 8-OH-DPAT and EMD 128130 to the regulation of haloperidol-induced muscle rigidity in rats. Neuropharmacology. vol 45. issue 8. 2004-02-11. PMID:14614949. contribution of the serotonin 5-ht1a receptor agonism of 8-oh-dpat and emd 128130 to the regulation of haloperidol-induced muscle rigidity in rats. 2004-02-11 2023-08-12 rat
E Lorenc-Koci, J Wardas, G D Bartoszyk, S Wolfart. Contribution of the serotonin 5-HT1A receptor agonism of 8-OH-DPAT and EMD 128130 to the regulation of haloperidol-induced muscle rigidity in rats. Neuropharmacology. vol 45. issue 8. 2004-02-11. PMID:14614949. the aim of the present study was to find out whether (+/-)-8-hydroxy-2(di-n-propylamino)tetralin (8-oh-dpat), a prototypical 5-ht1a agonist, and (r)-(-)-2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]-chromane hcl (emd 128130), a compound with serotonin 5-ht1a-agonist and dopamine d2-like antagonist properties, are able to attenuate the haloperidol-induced (1 mg/kg) muscle rigidity in rats. 2004-02-11 2023-08-12 rat
Russell H Hill, Erik Svensson, Yannick Dewael, Sten Grillne. 5-HT inhibits N-type but not L-type Ca(2+) channels via 5-HT1A receptors in lamprey spinal neurons. The European journal of neuroscience. vol 18. issue 11. 2004-01-29. PMID:14656287. 5-ht inhibits n-type but not l-type ca(2+) channels via 5-ht1a receptors in lamprey spinal neurons. 2004-01-29 2023-08-12 Not clear
Russell H Hill, Erik Svensson, Yannick Dewael, Sten Grillne. 5-HT inhibits N-type but not L-type Ca(2+) channels via 5-HT1A receptors in lamprey spinal neurons. The European journal of neuroscience. vol 18. issue 11. 2004-01-29. PMID:14656287. after incubation in pertussis toxin, to block gi/o proteins, 5-ht did not reduce ca(2+) currents, further indicating that the effect is caused by an activation of 5-ht1a receptors. 2004-01-29 2023-08-12 Not clear
William A Wol. SLV-308. Solvay. Current opinion in investigational drugs (London, England : 2000). vol 4. issue 7. 2004-01-22. PMID:14619412. solvay is developing slv-308 (sme-308), a partial dopamine d2 agonist and noradrenergic agonist with serotonin 5-ht1a agonist properties, for the potential oral treatment of parkinson's disease (pd), panic and depression. 2004-01-22 2023-08-12 Not clear
S Tucci, R F Genn, E Marco, S E Fil. Do different mechanisms underlie two anxiogenic effects of systemic nicotine? Behavioural pharmacology. vol 14. issue 4. 2004-01-21. PMID:12838038. alpha7 nicotinic acetylcholine receptors (alpha7 nachrs) and 5-hydroxytryptamine 1a (5-ht1a) receptors have been implicated in the anxiogenic effects of centrally administered nicotine, but the receptors that mediate the anxiogenic effects of systemic nicotine are not known. 2004-01-21 2023-08-12 Not clear
Fuxin Shi, Willy H Visser, Natasja M J de Jong, Robert S B Liem, Eric Ronken, Dick Hoekstr. Antisense oligonucleotides reach mRNA targets via the RNA matrix: downregulation of the 5-HT1A receptor. Experimental cell research. vol 291. issue 2. 2004-01-16. PMID:14644154. to address these issues, we employed phosphorothioate odns directed against specific regions of the mrna of the serotonin 5ht1a receptor, governed by sequence and structure. 2004-01-16 2023-08-12 Not clear
Janna E Slessareva, Hongzheng Ma, Karyn M Depree, Lori A Flood, Hyunsu Bae, Theresa M Cabrera-Vera, Heidi E Hamm, Stephen G Grabe. Closely related G-protein-coupled receptors use multiple and distinct domains on G-protein alpha-subunits for selective coupling. The Journal of biological chemistry. vol 278. issue 50. 2004-01-15. PMID:14525988. while the a1 adenosine receptor does not distinguish between gi1alpha and gtalpha sequences, the 5-ht1a and 5-ht1b serotonin and m2 muscarinic receptors can couple with gi1 but not gt. 2004-01-15 2023-08-12 Not clear
G Brousse, A Schmitt, I Chereau, A Eschalier, C Dubray, P-M Llorc. [Interest of the use of pindolol in the treatment of depression: review]. L'Encephale. vol 29. issue 4 Pt 1. 2004-01-14. PMID:14615704. the onset of antidepressant action of serotonin (5ht) selective reuptake inhibitors (ssris) was attributed in part to the decrease in firing activity of serotonin neurons produced by the activation of raphe 5ht1a autoreceptors at the time of treatment initiation. 2004-01-14 2023-08-12 Not clear
Mercè Amargós-Bosch, Albert Adell, Analía Bortolozzi, Francesc Artiga. Stimulation of alpha1-adrenoceptors in the rat medial prefrontal cortex increases the local in vivo 5-hydroxytryptamine release: reversal by antipsychotic drugs. Journal of neurochemistry. vol 87. issue 4. 2004-01-14. PMID:14622114. the application of the alpha1-adrenoceptor agonist cirazoline by reverse dialysis increased the prefrontal 5-ht release in a concentration-dependent manner, an effect antagonized by coperfusion of ttx, prazosin (alpha1-adrenoceptor antagonist), bay x 3702 (5-ht1a agonist), nbqx (ampa/ka antagonist) and 1s,3s-acpd (mglur ii/iii agonist), but not by mk-801 (nmda antagonist). 2004-01-14 2023-08-12 rat
Miki Kishitake, Korehito Yamanouch. Effects of highly or relatively selective 5-HT1A receptor agonists on lordosis in female rats. Zoological science. vol 20. issue 9. 2004-01-05. PMID:14578574. these results indicate that 5-ht1a is strongly involved in the lordosis-inhibiting circuit of the serotonin neurons. 2004-01-05 2023-08-12 rat
Saoussen Bouali, Alexis Evrard, Michel Chastanet, Klaus-Peter Lesch, Michel Hamon, Joëlle Adrie. Sex hormone-dependent desensitization of 5-HT1A autoreceptors in knockout mice deficient in the 5-HT transporter. The European journal of neuroscience. vol 18. issue 8. 2003-12-23. PMID:14622181. sex hormone-dependent desensitization of 5-ht1a autoreceptors in knockout mice deficient in the 5-ht transporter. 2003-12-23 2023-08-12 mouse
Murat Oz, Li Zhang, Alessandro Rotondo, Hui Sun, Marisela Morale. Direct activation by dopamine of recombinant human 5-HT1A receptors: comparison with human 5-HT2C and 5-HT3 receptors. Synapse (New York, N.Y.). vol 50. issue 4. 2003-12-19. PMID:14556235. in addition, the effect of da on the activation of three different types of human 5-ht receptors (5-ht1a, 5-ht2c, and 5-ht3) were studied comparatively in xenopus oocyte expression system. 2003-12-19 2023-08-12 human
Murat Oz, Li Zhang, Alessandro Rotondo, Hui Sun, Marisela Morale. Direct activation by dopamine of recombinant human 5-HT1A receptors: comparison with human 5-HT2C and 5-HT3 receptors. Synapse (New York, N.Y.). vol 50. issue 4. 2003-12-19. PMID:14556235. application of 5-ht or da in oocytes coexpressing 5-ht1a receptors and g-protein-activated inwardly rectifying potassium channels (girk1) induced inward currents with respective ec50 values of 4.2 nm and 11.2 microm. 2003-12-19 2023-08-12 human
Murat Oz, Li Zhang, Alessandro Rotondo, Hui Sun, Marisela Morale. Direct activation by dopamine of recombinant human 5-HT1A receptors: comparison with human 5-HT2C and 5-HT3 receptors. Synapse (New York, N.Y.). vol 50. issue 4. 2003-12-19. PMID:14556235. maximal responses induced by da were 85 +/- 4% of maximal 5-ht currents and da responses were blocked by the specific 5-ht1a antagonist, way-100635 (50 nm). 2003-12-19 2023-08-12 human
Murat Oz, Li Zhang, Alessandro Rotondo, Hui Sun, Marisela Morale. Direct activation by dopamine of recombinant human 5-HT1A receptors: comparison with human 5-HT2C and 5-HT3 receptors. Synapse (New York, N.Y.). vol 50. issue 4. 2003-12-19. PMID:14556235. in cho-k1 cells expressing 5-ht1a receptors, 5-ht and da inhibited the specific binding of selective antagonist [3h]-8-oh-dpat with ic50 values of 10.2 nm and 1.4 microm, and both 5-ht and da inhibited the forskolin-induced accumulation of camp. 2003-12-19 2023-08-12 human