| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hamed Alizadeh Pahlavan. Possible role of exercise therapy on depression: effector neurotransmitters as key players. Behavioural brain research. 2023-12-04. PMID:38048912. |
swimming exercise has antidepressant effects by increasing the sensitivity of serotonin 5-ht2 receptors and postsynaptic 5-ht1a receptors, increasing 5-ht and 5hiaa levels, increasing tph and serotonin, and decreasing inflammatory levels of ifn-γ and tnf-α. |
2023-12-04 |
2023-12-10 |
Not clear |
| Apeksha Parajulee, Kuglae Ki. Structural studies of serotonin receptor family. BMB reports. 2023-10-11. PMID:37817438. |
the functions of serotonin are mediated by a family of 5-ht receptors including 12 gpcrs belonging to six major families: 5-ht1, 5-ht2, 5-ht4, 5-ht5, 5-ht6 and 5-ht7. |
2023-10-11 |
2023-10-15 |
Not clear |
| Candice Muller, Jeanne Merignac, Christophe Moog, Benoit Schorr, Hervé Javelot, Frédéric Blan. [Pimavanserin and trazodone combination in behavioral disorders in severe dementia with Lewy bodies]. Geriatrie et psychologie neuropsychiatrie du vieillissement. vol 21. issue 1. 2023-04-28. PMID:37115687. |
trazodone is a serotonin reuptake inhibitor and a 5-ht2 receptor antagonist: it is effective in the treatment of the frontal syndrome and is commonly used in frontotemporal degeneration. |
2023-04-28 |
2023-08-14 |
Not clear |
| Eder Alejandro Rodríguez-Martínez, Cindy U Rivas, María E Ayala, Rodolfo Blanco-Rodríguez, Nancy Juarez, Esteban Hernández-Vargas, Andrés Aragó. A new computational approach, based on images trajectories, to identify the subjacent heterogeneity of sperm to the effects of ketanserin. Cytometry. Part A : the journal of the International Society for Analytical Cytology. 2023-03-28. PMID:36974731. |
semen samples of boar sperm were treated with distinct concentrations of ketanserin (an antagonist of the 5-ht2 receptor of serotonin) and untreated samples were used as a control. |
2023-03-28 |
2023-08-14 |
Not clear |
| Xiaolong Gao, Mo Zhang, Shihui Lin, Mingxin Lyu, Xuan Luo, Weiwei You, Caihuan K. Reproduction strategy of nocturnal marine molluscs: running for love. Integrative zoology. 2023-01-07. PMID:36609825. |
after 24 h uninterrupted sampling, the concentration of 5-ht and the expression levels of the 5-ht2 and 5-ht6 receptors in am were significantly higher than those in jm. |
2023-01-07 |
2023-08-14 |
Not clear |
| Xiaolong Gao, Mo Zhang, Shihui Lin, Mingxin Lyu, Xuan Luo, Weiwei You, Caihuan K. Reproduction strategy of nocturnal marine molluscs: running for love. Integrative zoology. 2023-01-07. PMID:36609825. |
after further injection of 5-ht2 and 5-ht6 receptor antagonists, the concentrations of camp and pka rose again, but the cumulative movement duration and distance of male abalones decreased significantly, showing that 5-ht was involved in the regulation of movement behavior of male abalones through the 5-ht2 and 5-ht6 receptor-activated camp-pka pathways. |
2023-01-07 |
2023-08-14 |
Not clear |
| P Campos-Bedolla, E G Torrejón-González, D Mendoza-Mejía, M H Vargas, P Segura-Medina, V Carbajal-Salinas, A Rodríguez-Márquez, A Valeria Martínez-Silv. Role of 5-HT2 receptors family in the allergy-induced increased aorta contractile responses to 5-HT. Physiological research. 2022-12-22. PMID:36545875. |
role of 5-ht2 receptors family in the allergy-induced increased aorta contractile responses to 5-ht. |
2022-12-22 |
2023-08-14 |
Not clear |
| Adam Wichniak, Aleksandra Ewa Wierzbicka, Marek Jarem. Treatment of insomnia - effect of trazodone and hypnotics on sleep. Psychiatria polska. vol 55. issue 4. 2022-01-07. PMID:34994734. |
the main mechanism through which trazodone promotes sleep is its antagonistic effect on 5-ht2 serotonin receptors, while hypnotics are agonists of gamma-aminobutyric acid gabaa receptors, and other sedative antidepressants block h1 histamine receptors. |
2022-01-07 |
2023-08-13 |
Not clear |
| Qian Qian Liu, Xiao Xiao Yao, Shuo Hui Gao, Rui Li, Bing Jin Li, Wei Yang, Ran Ji Cu. Role of 5-HT receptors in neuropathic pain: potential therapeutic implications. Pharmacological research. vol 159. 2021-07-05. PMID:32464329. |
therefore, we summarized the recent findings on multiple subtypes of 5-ht receptors in both central and peripheral nervous system in neuropathic pain, particularly, 5-ht1, 5-ht2, 5-ht3 and 5-ht7 receptors. |
2021-07-05 |
2023-08-13 |
Not clear |
| Miguel A Núñez-Ochoa, Gustavo A Chiprés-Tinajero, Laura Medina-Cej. Evaluation of the hippocampal immunoreactivity of the serotonin 5-HT1A, 5-HT2 and 5-HT7 receptors in a pilocarpine temporal lobe epilepsy rat model with fast ripples. Neuroreport. vol 32. issue 4. 2021-06-18. PMID:33470771. |
evaluation of the hippocampal immunoreactivity of the serotonin 5-ht1a, 5-ht2 and 5-ht7 receptors in a pilocarpine temporal lobe epilepsy rat model with fast ripples. |
2021-06-18 |
2023-08-13 |
rat |
| Miguel A Núñez-Ochoa, Gustavo A Chiprés-Tinajero, Laura Medina-Cej. Evaluation of the hippocampal immunoreactivity of the serotonin 5-HT1A, 5-HT2 and 5-HT7 receptors in a pilocarpine temporal lobe epilepsy rat model with fast ripples. Neuroreport. vol 32. issue 4. 2021-06-18. PMID:33470771. |
therefore, to gather more details about the state of the serotoninergic system in the hippocampus under an epileptogenic process, we studied the immunoreactivity of three 5-ht receptors (5-ht1a, 5-ht2 and 5-ht7) as well as the extracellular levels of 5-ht in the hippocampal tissue of epileptic rats with fr. |
2021-06-18 |
2023-08-13 |
rat |
| Shaul Schreiber, Chaim G Pic. The Opioid Interactions of the Antipsychotic Medications Risperidone and Amisulpride in Mice and Their Potential Use in the Treatment of Other Non-Psychotic Medical Conditions. Cellular and molecular neurobiology. vol 41. issue 5. 2021-05-28. PMID:33184770. |
risperidone is a neuroleptic with a potent dopamine d2 and serotonin 5-ht2 receptor-blocking activity as well as a high affinity for adrenergic and histamine h1 receptors. |
2021-05-28 |
2023-08-13 |
mouse |
| Hera Wu, DeVon Herr, Nancie J MacIver, Jeffrey C Rathmell, Valerie A Gerriet. CD4 T cells differentially express cellular machinery for serotonin signaling, synthesis, and metabolism. International immunopharmacology. vol 88. 2021-05-25. PMID:32866787. |
we therefore examined the serotonergic-related machinery in teff and treg and found differential expression of the serotonin transporter sert and 5-ht1a and 5-ht2 receptors. |
2021-05-25 |
2023-08-13 |
Not clear |
| Takuto Ishida, Hiroyuki Uchida, Satoru Kaneko, Kazuhiro Sugiyama, Yuichi Hamabe, Masaru Mimura, Takefumi Suzuk. Life-Threatening Serotonin Syndrome Precipitated by Discontinuation of Serotonin-Dopamine Antagonist in the Presence of Serotonergic Agents: A Case Report. Clinical neuropharmacology. vol 43. issue 3. 2021-04-12. PMID:32217863. |
although the discontinuation of antipsychotics with 5-ht2 receptor antagonistic characteristics could theoretically result in serotonin syndrome, there have been very few reports on the syndrome thus far. |
2021-04-12 |
2023-08-13 |
Not clear |
| Michael James Winkelma. The Evolved Psychology of Psychedelic Set and Setting: Inferences Regarding the Roles of Shamanism and Entheogenic Ecopsychology. Frontiers in pharmacology. vol 12. 2021-03-20. PMID:33732156. |
effects of 5ht2 psychedelics on serotonin, stress adaptation, visual systems and personality illustrate adaptive mechanisms through which psychedelics could have enhanced hominin evolution as an environmental factor influencing selection for features of our evolved psychology. |
2021-03-20 |
2023-08-13 |
chimpanzee |
| Mahmoud Gholyaf, Vida Sheikh, Fatemeh Yasrebifar, Younes Mohammadi, Mahtabalsadat Mirjalili, Maryam Mehrpooy. Effect of mirtazapine on pruritus in patients on hemodialysis: a cross-over pilot study. International urology and nephrology. vol 52. issue 6. 2021-02-26. PMID:32383050. |
the present study was designed to investigate the effectiveness of mirtazapine, an atypical antidepressant agent with potent antagonistic activity against serotonin (5ht2, 5ht3) and histamine (h1) receptors, in the treatment of pruritus in hemodialysis (hd) patients. |
2021-02-26 |
2023-08-13 |
Not clear |
| Xueliang Shang, Congying You, Xiang Li, Lu Yuan, Meng Jin, Xiujun Zhan. Involvement of 5-HT2 serotonin receptors in cognitive defects induced by aristolochic acid I in mice. Toxicology. vol 447. 2021-01-14. PMID:33186629. |
involvement of 5-ht2 serotonin receptors in cognitive defects induced by aristolochic acid i in mice. |
2021-01-14 |
2023-08-13 |
mouse |
| Christian M Gallardo, Camille S Martin, Andrew D Steel. Food Anticipatory Activity on Circadian Time Scales Is Not Dependent on Central Serotonin: Evidence From Tryptophan Hydroxylase-2 and Serotonin Transporter Knockout Mice. Frontiers in molecular neuroscience. vol 13. 2020-12-15. PMID:33041772. |
several studies have implicated serotonin as a negative regulator of faa: (1) aged rats treated with serotonin 5-ht2 and 3 receptor antagonists showed enhanced faa, (2) mice lacking for the 2c serotonin receptor demonstrate enhanced faa, and (3) pharmacologically increased serotonin levels suppressed faa while decreased serotonin levels enhanced faa in mice. |
2020-12-15 |
2023-08-13 |
mouse |
| Jeong Soo Lee, Seong Yong Park, Na Young Kim, Dong Wook Kim, Ju Eun Oh, Eunjin Heo, Jong Seok Lee, Young Chul Yo. Anti-Tumor Potential of a 5-HT3 Receptor Antagonist as a Novel Autophagy Inducer in Lung Cancer: A Retrospective Clinical Study with In Vitro Confirmation. Journal of clinical medicine. vol 8. issue 9. 2020-10-01. PMID:31484445. |
unlike 5-hydroxytryptamine (5-ht, serotonin) 1 and 5-ht2, the effect of 5-ht3 receptors on tumor cells is poorly understood. |
2020-10-01 |
2023-08-13 |
human |
| Taichi Ochi, Natalya M Vyalova, Innokentiy S Losenkov, Diana Z Paderina, Ivan V Pozhidaev, Anton J M Loonen, German G Simutkin, Nikolay A Bokhan, Svetlana A Ivanova, Bob Wilffer. Limited Associations Between 5-HT Receptor Gene Polymorphisms and Treatment Response in Antidepressant Treatment-Free Patients With Depression. Frontiers in pharmacology. vol 10. 2020-09-30. PMID:31956308. |
serotonin regulation of amygdala activity is attained through activation of three 5-ht2 family receptor subtypes, 5-ht2a, 5-ht2b, and 5-ht2c. |
2020-09-30 |
2023-08-13 |
Not clear |