All Relations between 5-ht receptor 2 and serotonin

Publication Sentence Publish Date Extraction Date Species
J Costenti. [A new approach to antischizophrenic therapeutics: D2 dopamine receptor partial agonists]. Annales pharmaceutiques francaises. vol 67. issue 5. 2009-11-17. PMID:19695367. the latter drugs display such properties on account of several associated pharmacological activities (d3 receptors antagonism more efficient than d2 antagonism; antagonism at cholinergic muscarinic receptors; antagonism at 5ht2 serotonin receptors). 2009-11-17 2023-08-12 Not clear
Mitsuko Kanamaru, Ikuo Homm. Dorsomedial medullary 5-HT2 receptors mediate immediate onset of initial hyperventilation, airway dilation, and ventilatory decline during hypoxia in mice. American journal of physiology. Regulatory, integrative and comparative physiology. vol 297. issue 1. 2009-08-25. PMID:19386986. effects of 5-ht in the dmm on ventilatory augmentation and airway dilation are mediated via 5-ht2 receptors, which interact with the co(2) drive. 2009-08-25 2023-08-12 mouse
Mitsuko Kanamaru, Ikuo Homm. Dorsomedial medullary 5-HT2 receptors mediate immediate onset of initial hyperventilation, airway dilation, and ventilatory decline during hypoxia in mice. American journal of physiology. Regulatory, integrative and comparative physiology. vol 297. issue 1. 2009-08-25. PMID:19386986. in the present study, effects of 5-ht2 receptors in the dmm on hypoxic ventilatory and airway responses were investigated, while 5-ht release in the dmm was monitored. 2009-08-25 2023-08-12 mouse
Mitsuko Kanamaru, Ikuo Homm. Dorsomedial medullary 5-HT2 receptors mediate immediate onset of initial hyperventilation, airway dilation, and ventilatory decline during hypoxia in mice. American journal of physiology. Regulatory, integrative and comparative physiology. vol 297. issue 1. 2009-08-25. PMID:19386986. these results suggest that 5-ht release increased by hypoxia acts on 5-ht2 receptors in the dmm, which contributes to the immediate onset of initial hypoxic hyperventilation, airway dilation, and subsequent ventilatory decline. 2009-08-25 2023-08-12 mouse
Johan Fernø, Audun O Vik-Mo, Goran Jassim, Bjarte Håvik, Kjetil Berge, Silje Skrede, Oddrun A Gudbrandsen, Jo Waage, Niclas Lunder, Sverre Mørk, Rolf K Berge, Hugo A Jørgensen, Vidar M Stee. Acute clozapine exposure in vivo induces lipid accumulation and marked sequential changes in the expression of SREBP, PPAR, and LXR target genes in rat liver. Psychopharmacology. vol 203. issue 1. 2009-06-02. PMID:18989661. these lipid-related effects have been attributed to drug-mediated blockade or antagonism of histamine h1 and serotonin 5-ht2 receptors as well as activation of hypothalamic amp-activated protein kinase. 2009-06-02 2023-08-12 rat
Takao Hirai, Kohji Tokumo, Daijyu Tsuchiya, Hiroaki Nishi. Expression of mRNA for 5-HT2 receptors and proteins related to inactivation of 5-HT in mouse osteoblasts. Journal of pharmacological sciences. vol 109. issue 2. 2009-05-08. PMID:19212095. expression of mrna for 5-ht2 receptors and proteins related to inactivation of 5-ht in mouse osteoblasts. 2009-05-08 2023-08-12 mouse
Jesse A May, Najam A Sharif, Hwang-Hsing Chen, John C Liao, Curtis R Kelly, Richard A Glennon, Richard Young, Jun-Xu Li, Kenner C Rice, Charles P Franc. Pharmacological properties and discriminative stimulus effects of a novel and selective 5-HT2 receptor agonist AL-38022A [(S)-2-(8,9-dihydro-7H-pyrano[2,3-g]indazol-1-yl)-1-methylethylamine]. Pharmacology, biochemistry, and behavior. vol 91. issue 3. 2009-04-02. PMID:18718483. al-38022a is a novel synthetic serotonergic (5-ht) ligand that exhibited high affinity for each of the 5-ht2 receptor subtypes (ki100-fold less) affinity for other 5-ht receptors. 2009-04-02 2023-08-12 human
Jesse A May, Najam A Sharif, Hwang-Hsing Chen, John C Liao, Curtis R Kelly, Richard A Glennon, Richard Young, Jun-Xu Li, Kenner C Rice, Charles P Franc. Pharmacological properties and discriminative stimulus effects of a novel and selective 5-HT2 receptor agonist AL-38022A [(S)-2-(8,9-dihydro-7H-pyrano[2,3-g]indazol-1-yl)-1-methylethylamine]. Pharmacology, biochemistry, and behavior. vol 91. issue 3. 2009-04-02. PMID:18718483. the pharmacological profile of al-38022a suggests that it could be a useful tool in defining 5-ht2 receptor signaling and receptor characterization where 5-ht may function as a neurotransmitter. 2009-04-02 2023-08-12 human
William M Connelly, Matthew J Baggot. Role of endocannabinoids in 5-HT2 receptor-mediated effects. Journal of neurophysiology. vol 101. issue 1. 2009-03-13. PMID:19004992. we review a recent report that activation of metabotropic 5-ht2 receptors by endogenous serotonin induces the release of endocannabinoids in the olivary nucleus and suppresses glutamatergic input through a presynaptic action. 2009-03-13 2023-08-12 Not clear
A E Lychkov. Serotoninergic system in the development of pyloric stenosis and pancreatitis. Bulletin of experimental biology and medicine. vol 146. issue 2. 2009-03-06. PMID:19145332. pyloric stenosis and pancreatitis were simulated before and after administration of serotonin and spiperone (5-ht2 receptor blocker). 2009-03-06 2023-08-12 Not clear
Jeremy Goldberg, George M Anderson, Lonnie Zwaigenbaum, Geoffrey B C Hall, Claude Nahmias, Ann Thompson, Peter Szatmar. Cortical serotonin type-2 receptor density in parents of children with autism spectrum disorders. Journal of autism and developmental disorders. vol 39. issue 1. 2009-03-05. PMID:18592367. parents (n = 19) of children with autism spectrum disorders (asd) and adult controls (n = 17) underwent positron emission tomography (pet) using [(18)f]setoperone to image cortical serotonin type-2 (5-ht2) receptors. 2009-03-05 2023-08-12 Not clear
Jeremy Goldberg, George M Anderson, Lonnie Zwaigenbaum, Geoffrey B C Hall, Claude Nahmias, Ann Thompson, Peter Szatmar. Cortical serotonin type-2 receptor density in parents of children with autism spectrum disorders. Journal of autism and developmental disorders. vol 39. issue 1. 2009-03-05. PMID:18592367. cortical 5-ht2 bps were significantly lower in parents compared to controls and platelet 5-ht levels were significantly negatively correlated with cortical 5-ht2 bp in parents. 2009-03-05 2023-08-12 Not clear
S V Yurtaeva, A A Obynochny, Kh L Gainutdinov, G G Jafarova, L N Muranova, V V Kirilova, R R Nigmatullin. Electron paramagnetic resonance study of nitric oxide production during 5-HT2 receptor blockade in the blood, heart, and liver of rats with myocardial infarction. Bulletin of experimental biology and medicine. vol 145. issue 6. 2009-03-03. PMID:19110557. the effect of serotonin 5-ht2 receptor blockade on nitric oxide production in rats with myocardial infarction was evaluated by the method of electron paramagnetic resonance. 2009-03-03 2023-08-12 rat
Lihua Liang, Kelvin MacDonald, Erik M Schwiebert, Pamela L Zeitlin, William B Guggin. Spiperone, identified through compound screening, activates calcium-dependent chloride secretion in the airway. American journal of physiology. Cell physiology. vol 296. issue 1. 2009-02-26. PMID:18987251. we found that spiperone, a known antipsychotic drug, is a potent intracellular ca2+ enhancer and demonstrated that it stimulates intracellular ca2+, not by acting in its well-known role as an antagonist of serotonin 5-ht2 or dopamine d2 receptors, but through a protein tyrosine kinase-coupled phospholipase c-dependent pathway. 2009-02-26 2023-08-12 mouse
Andrew G Ramage, Carlos M Villaló. 5-hydroxytryptamine and cardiovascular regulation. Trends in pharmacological sciences. vol 29. issue 9. 2009-01-30. PMID:19086344. these reflexes also affect activity in the sympathetic nervous system, which itself can be inhibited by central 5-ht(1a) receptors to cause falls in blood pressure and excited by 5-ht2 receptors to cause rises in blood pressure. 2009-01-30 2023-08-12 Not clear
Aart S de Leeuw, Herman G M Westenber. Hypersensitivity of 5-HT2 receptors in OCD patients. An increased prolactin response after a challenge with meta-chlorophenylpiperazine and pre-treatment with ritanserin and placebo. Journal of psychiatric research. vol 42. issue 11. 2008-12-03. PMID:18533183. to further examine the role of 5-ht receptors we studied the behavioural and neuroendocrine effects of different doses of meta-chlorophenylpiperazine (mcpp) in ocd patients and healthy controls, after pre-treatment with ritanserin, a 5-ht2 receptor antagonist, and placebo. 2008-12-03 2023-08-12 Not clear
Olga Dergacheva, Xin Wang, Harriet Kamendi, Qi Cheng, Ramon Manchon Pinol, Heather Jameson, Christopher Gorini, David Mendelowit. 5HT2 receptor activation facilitates P2X receptor mediated excitatory neurotransmission to cardiac vagal neurons in the nucleus ambiguus. Neuropharmacology. vol 54. issue 7. 2008-10-14. PMID:18396300. serotonin (5ht), and in particular 5ht2 receptors, play an important role in cardiovascular function in the brainstem. 2008-10-14 2023-08-12 Not clear
V V Kirillova, R K Dzhordzhikiya, R R Nigmatullin. Adrenergic and serotoninergic regulation of myocardial contractility in patients with various morphofunctional changes in the heart resulting from chronic heart failure. Bulletin of experimental biology and medicine. vol 144. issue 4. 2008-10-02. PMID:18642697. during left ventricular hypertrophy, the strength of myocardial contraction in response to serotonin exceeded that induced by epinephrine and was realized via 5-ht2 receptors. 2008-10-02 2023-08-12 Not clear
Yukio Ago, Shigeo Nakamura, Shinsuke Arikawa, Miyuki Yata, Toshio Matsud. [Involvement of prefrontal serotonergic neurons in methamphetamine-induced behavioral sensitization]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology. vol 28. issue 2. 2008-07-24. PMID:18516987. we demonstrated that the activation of serotonin (5-ht) receptors or blockade of 5-ht2 receptors, given after establishment of the sensitization, attenuates the expression of methamphetamine-induced behavioral sensitization in mice. 2008-07-24 2023-08-12 mouse
Liesbeth A Bruins Slot, Laurent Bardin, Agnès L Auclair, Ronan Depoortere, Adrian Newman-Tancred. Effects of antipsychotics and reference monoaminergic ligands on marble burying behavior in mice. Behavioural pharmacology. vol 19. issue 2. 2008-06-17. PMID:18332679. inhibition of marble burying behavior may result from the interplay of several receptor systems, including 5-ht2 receptor blockade, dopamine d2 partial agonism and serotonin 5-ht1a agonism. 2008-06-17 2023-08-12 mouse