| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mo Yang, Karen Li, Pak Cheung Ng, Carmen Ka Yee Chuen, Tze Kin Lau, Yuan Shan Cheng, Yuan Sheng Liu, Chi Kong Li, Patrick Man Pan Yuen, Anthony Edward James, Shuk Man Lee, Tai Fai Fo. Promoting effects of serotonin on hematopoiesis: ex vivo expansion of cord blood CD34+ stem/progenitor cells, proliferation of bone marrow stromal cells, and antiapoptosis. Stem cells (Dayton, Ohio). vol 25. issue 7. 2007-08-01. PMID:17446559. |
the addition of ketanserin, a competitive antagonist of 5-ht2 receptor, nullified the antiapoptotic effects of serotonin. |
2007-08-01 |
2023-08-12 |
human |
| P A Polo, R O Reis, P L Cedraz-Mercez, H R Cavalcante-Lima, E L Olivares, M A Medeiros, W S Côrtes, L C Rei. Behavioral and neuropharmacological evidence that serotonin crosses the blood-brain barrier in Coturnix japonica (Galliformes; Aves). Brazilian journal of biology = Revista brasleira de biologia. vol 67. issue 1. 2007-07-30. PMID:17505765. |
studies using serotoninergic agonist and antagonists have disclosed that among the actions of the serotonin, feather bristling, rapid oral movements and yawning-like state originated from activation of 5-ht2 receptors while blinking and closure of the eyes possibly require other subtypes of receptors. |
2007-07-30 |
2023-08-12 |
Not clear |
| Thomas J Raedler, Jens Reimer, Klaus Wiedeman. Dose-dependent constipation with higher doses of quetiapine: a case series. International clinical psychopharmacology. vol 22. issue 4. 2007-07-24. PMID:17519649. |
quetiapine is a dopamine d2 and serotonin 5-ht2 antagonist with antipsychotic and mood-stabilizing properties. |
2007-07-24 |
2023-08-12 |
Not clear |
| Ole F Olesen, Bente Bennike, Henrik Dam, Erling Melleru. Association of the 5-HT2A receptor gene polymorphism 102T/C with ischemic stroke. Journal of molecular neuroscience : MN. vol 30. issue 3. 2007-05-24. PMID:17401157. |
serotonin (5-ht) has been implicated in a number of cardiovascular disorders due to its ability to induce vascular contraction and platelet aggregation through activation of the 5-ht2 receptor family. |
2007-05-24 |
2023-08-12 |
Not clear |
| Mikael Landén, Michael E Thas. A model to explain the therapeutic effects of serotonin reuptake inhibitors: the role of 5-HT2 receptors. Psychopharmacology bulletin. vol 39. issue 1. 2007-04-03. PMID:17065978. |
a model to explain the therapeutic effects of serotonin reuptake inhibitors: the role of 5-ht2 receptors. |
2007-04-03 |
2023-08-12 |
Not clear |
| W Stephen Waring, Alison M Good, D Nicholas Batema. Lack of significant toxicity after mirtazapine overdose: a five-year review of cases admitted to a regional toxicology unit. Clinical toxicology (Philadelphia, Pa.). vol 45. issue 1. 2007-03-29. PMID:17357381. |
mirtazapine is a comparatively new antidepressant that selectively blocks central alpha2-adrenergic autoreceptors and postsynaptic 5-ht2 and 5-ht3 receptors, causing reduced neuronal norepinephrine and serotonin reuptake. |
2007-03-29 |
2023-08-12 |
Not clear |
| Takashi Takeuchi, Ko Furuta, Toshiyuki Hirasawa, Hidekazu Masaki, Tomoaki Yukizane, Hidenori Atsuta, Toru Nishikaw. Perospirone in the treatment of patients with delirium. Psychiatry and clinical neurosciences. vol 61. issue 1. 2007-03-07. PMID:17239041. |
perospirone is a recently developed atypical antipsychotic with potent serotonin 5-ht2 and dopamine d2 antagonist activity. |
2007-03-07 |
2023-08-12 |
Not clear |
| Léa Stankovski, Chantal Alvarez, Tanja Ouimet, Tania Vitalis, Khalid H El-Hachimi, David Price, Evan Deneris, Patricia Gaspar, Olivier Case. Developmental cell death is enhanced in the cerebral cortex of mice lacking the brain vesicular monoamine transporter. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 6. 2007-03-06. PMID:17287506. |
altogether, these results suggest that high levels of serotonin, acting through 5-ht2 receptors, have neuroprotective action on cortical neurons by controlling bcl-x(l) mrna levels and that this action is independent of trkb signaling. |
2007-03-06 |
2023-08-12 |
mouse |
| V I Kulinskiĭ, S S Gavrilo. [Influence of the selective ligands of dopamine and 5-hydroxytryptamine receptors on the tolerance to global cerebral ischemia]. Eksperimental'naia i klinicheskaia farmakologiia. vol 69. issue 6. 2007-02-20. PMID:17209458. |
as for d and 5-ht (hydroxytryptamine) antagonists, only d1 antagonist sch 23390 and 5-ht2 antagonist ketanserin produce a small neuroprotective effect, while d2, d4, 5-ht(2b) and 5-ht(2c) antagonists are not active. |
2007-02-20 |
2023-08-12 |
Not clear |
| P Lacolley, J R Owen, K Sandock, T H J Lewis, J N Bates, T P Robertson, S J Lewi. 5-HT activates vagal afferent cell bodies in vivo: role of 5-HT2 and 5-HT3 receptors. Neuroscience. vol 143. issue 1. 2007-01-26. PMID:17029799. |
5-ht activates vagal afferent cell bodies in vivo: role of 5-ht2 and 5-ht3 receptors. |
2007-01-26 |
2023-08-12 |
rat |
| P Lacolley, J R Owen, K Sandock, T H J Lewis, J N Bates, T P Robertson, S J Lewi. 5-HT activates vagal afferent cell bodies in vivo: role of 5-HT2 and 5-HT3 receptors. Neuroscience. vol 143. issue 1. 2007-01-26. PMID:17029799. |
administration, and (2) functional 5-ht3 and 5-ht2 receptors exist on the cell bodies of vagal afferent neurons mediating the cardiovascular responses elicited by oa injections of 5-ht. |
2007-01-26 |
2023-08-12 |
rat |
| P Lacolley, J R Owen, K Sandock, T H J Lewis, J N Bates, T P Robertson, S J Lewi. 5-HT activates vagal afferent cell bodies in vivo: role of 5-HT2 and 5-HT3 receptors. Neuroscience. vol 143. issue 1. 2007-01-26. PMID:17029799. |
these findings also support a wealth of evidence that 5-ht3 receptors exist on the peripheral terminals of vagal afferents, and although they do not discount the possibility that 5-ht2 receptors exist on peripheral vagal afferent terminals, it appears that activation of these receptors does not have pronounced effects on 5-ht3 receptor activity on terminals that mediate the hemodynamic responses to 5-ht. |
2007-01-26 |
2023-08-12 |
rat |
| Yuan-Sheng Liu, Mo Yan. The effect of 5-hydroxtryptamine on the regulation of megakaryocytopoiesis. Hematology (Amsterdam, Netherlands). vol 11. issue 1. 2006-12-27. PMID:16522551. |
5-ht mainly binds to 5-ht2 receptors or 5-ht1 receptors on cell surfaces to stimulate cell proliferation through ras or mapk (mitogen-activated protein kinase) pathways in many cell types. |
2006-12-27 |
2023-08-12 |
Not clear |
| J Song, D Hanniford, C Doucette, E Graham, M F Poole, A Ting, B Sherf, J Harrington, K Brunden, A Stricker-Krongra. Development of homogeneous high-affinity agonist binding assays for 5-HT2 receptor subtypes. Assay and drug development technologies. vol 3. issue 6. 2006-12-20. PMID:16438660. |
the serotonin (5-hydroxytryptamine) 5-ht2 receptor subfamily consists of three members, 5-ht2a, 5-ht2b, and 5-ht2c. |
2006-12-20 |
2023-08-12 |
human |
| Theodore A Slotkin, Charlotte A Tate, Mandy M Cousins, Frederic J Seidle. Prenatal nicotine exposure alters the responses to subsequent nicotine administration and withdrawal in adolescence: Serotonin receptors and cell signaling. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 31. issue 11. 2006-12-12. PMID:16341021. |
prenatal nicotine exposure, which elicits damage to 5ht projections in the cerebral cortex and striatum, produced sex-selective changes in the expression of 5ht(1a) and 5ht2 receptors, along with induction of adenylyl cyclase (ac), leading to sensitization of heterologous inputs operating through this signaling pathway. |
2006-12-12 |
2023-08-12 |
rat |
| Laura M Hurle. Different serotonin receptor agonists have distinct effects on sound-evoked responses in inferior colliculus. Journal of neurophysiology. vol 96. issue 5. 2006-12-06. PMID:16870843. |
to determine whether activation of different types of serotonin receptors is a source of the variability in serotonergic effects, four selective agonists of serotonin receptors in the serotonin (5-ht) 1 and 5-ht2 families were iontophoretically applied to ic neurons, which were monitored for changes in their responses to auditory stimuli. |
2006-12-06 |
2023-08-12 |
Not clear |
| C Grasso, G Li Volsi, F Licata, L Ciranna, F Santangel. Aminergic control of neuronal firing rate in thalamic motor nuclei of the rat. Archives italiennes de biologie. vol 144. issue 3-4. 2006-11-01. PMID:16977832. |
inhibitory responses to 5-ht were partially mimicked by application of the 5-ht(1a) receptor agonist 8-hydroxy-2(di-n-propylamino)tetralin (8-oh-dpat) and of the 5-ht2 receptor agonist alpha-methyl-5-hydroxytryptamine (alpha-met-5-ht). |
2006-11-01 |
2023-08-12 |
rat |
| Byung Do Nam, Hee Ju Par. Side specific effect of 5-hydroxytryptamine on NaCl transport in the apical and basolateral membrane of rat tracheal epithelia. Physiological research. vol 55. issue 4. 2006-10-31. PMID:16238461. |
functional localization using selective 5-ht agonists and antagonists suggest that i(cl)(sc)is stimulated by the basolateral membrane-resident 5-ht receptors, whereas i(na)(sc) is inhibited by the apical membrane-resident 5-ht2 receptors. |
2006-10-31 |
2023-08-12 |
rat |
| C Sévoz-Couche, M A Comet, J F Bernard, M Hamon, R Laguzz. Cardiac baroreflex facilitation evoked by hypothalamus and prefrontal cortex stimulation: role of the nucleus tractus solitarius 5-HT2A receptors. American journal of physiology. Regulatory, integrative and comparative physiology. vol 291. issue 4. 2006-10-30. PMID:16763082. |
we previously showed that serotonin (5-ht2) receptor activation in the nucleus of the tractus solitarius (nts) produced hypotension, bradycardia, and facilitation of the baroreflex bradycardia. |
2006-10-30 |
2023-08-12 |
rat |
| Richard G Ruddell, Fiona Oakley, Ziafat Hussain, Irene Yeung, Lesley J Bryan-Lluka, Grant A Ramm, Derek A Man. A role for serotonin (5-HT) in hepatic stellate cell function and liver fibrosis. The American journal of pathology. vol 169. issue 3. 2006-10-24. PMID:16936262. |
treatment of hscs with 5-ht2 antagonists suppressed proliferation and elevated their rate of apoptosis; by contrast 5-ht was protective against nerve growth factor-induced apoptosis. |
2006-10-24 |
2023-08-12 |
human |