| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jing Liu, Xing-Quan Ji, Xing-Zu Zh. Comparison of psychic emergence reactions after (+/-)-ketamine and (+)-ketamine in mice. Life sciences. vol 78. issue 16. 2006-04-11. PMID:16289139. |
these results suggest that the (+)-ketamine has fewer posthypnotic side effects than (+/-)-ketamine when (+)-ketamine and (+/-)-ketamine were administered at equihypnotic dosages and that dopamine d2 and serotonin 5-ht2 receptor were not involved in the effects of (+)-ketamine and (+/-)-ketamine. |
2006-04-11 |
2023-08-12 |
mouse |
| John C Talpos, Lawrence S Wilkinson, Trevor W Robbin. A comparison of multiple 5-HT receptors in two tasks measuring impulsivity. Journal of psychopharmacology (Oxford, England). vol 20. issue 1. 2006-03-29. PMID:16204332. |
to test this hypothesis, behavioural effects of three partially selective serotonergic (5-ht) ligands, ketanserin (5-ht2(a, c) receptor antagonist), ser-082 (5-ht2(c, b) receptor antagonist) and sb-270146-a (5-ht6 receptor antagonist) were compared in two tests of impulsivity. |
2006-03-29 |
2023-08-12 |
Not clear |
| A E Frampton, J C H Andrews, A Parfitt, I A Jagroop, D P Mikhailidis, J A Henr. Does meta-chlorophenylpiperazine (mCPP) activate human platelets? Platelets. vol 17. issue 1. 2006-03-29. PMID:16308184. |
mcpp (meta-chlorophenylpiperazine), an agonist at serotonin (5-hydroxytryptamine, 5-ht) 5-ht2 receptors, has been used as a probe of serotonergic function. |
2006-03-29 |
2023-08-12 |
human |
| Daniela Popa, Clément Léna, Véronique Fabre, Caroline Prenat, Jay Gingrich, Pierre Escourrou, Michel Hamon, Joëlle Adrie. Contribution of 5-HT2 receptor subtypes to sleep-wakefulness and respiratory control, and functional adaptations in knock-out mice lacking 5-HT2A receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 49. 2006-03-23. PMID:16339018. |
here, we investigated the relative contribution of 5-ht(2a), 5-ht(2b), and 5-ht(2c) receptor subtypes to nrems and breathing during sleep, using 5-ht2 subtype-selective ligands in wild-type (5-ht(2a)+/+) and knock-out (5-ht(2a)-/-) mice that do not express 5-ht(2a) receptors. |
2006-03-23 |
2023-08-12 |
mouse |
| Ennio Esposit. Serotonin-dopamine interaction as a focus of novel antidepressant drugs. Current drug targets. vol 7. issue 2. 2006-03-10. PMID:16475959. |
among the multiple classes of 5-ht receptors described in the central nervous system, much attention has been devoted to the role of 5-ht2 receptor family in the control of central dopaminergic activity, because of the moderate to dense localization of both transcript and protein for 5-ht2a and 5-ht2c receptors in the substantia nigra (sn) and ventral tegmental area (vta), as well as their terminal regions. |
2006-03-10 |
2023-08-12 |
human |
| Jean-François Perrier, Rodolfo Delgado-Lezam. Synaptic release of serotonin induced by stimulation of the raphe nucleus promotes plateau potentials in spinal motoneurons of the adult turtle. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 35. 2006-03-07. PMID:16135756. |
our study suggests that cav1.3 channels are regulated by 5-ht released from raphe spinal synaptic terminals via 5-ht2 receptors. |
2006-03-07 |
2023-08-12 |
Not clear |
| Yinglin Liu, Barry L Fanbur. Serotonin-induced growth of pulmonary artery smooth muscle requires activation of phosphatidylinositol 3-kinase/serine-threonine protein kinase B/mammalian target of rapamycin/p70 ribosomal S6 kinase 1. American journal of respiratory cell and molecular biology. vol 34. issue 2. 2006-02-23. PMID:16195541. |
akt phosphorylation and cell proliferation were also blocked by the antioxidants, n-acetyl-l-cysteine, ginko biloba 501, and tiron, the reduced nicotinamide adenine dinucleotide phosphate oxidase inhibitor, diphenyleneiodonium, and the 5-ht2 receptor antagonists ketanserin and mianserin, but not by the 5-ht serotonin transporter or 5-ht 1b/1d receptor antagonists. |
2006-02-23 |
2023-08-12 |
Not clear |
| Malgorzata Filip, Marcy J Bubar, Kathryn A Cunningha. Contribution of serotonin (5-HT) 5-HT2 receptor subtypes to the discriminative stimulus effects of cocaine in rats. Psychopharmacology. vol 183. issue 4. 2006-01-31. PMID:16261316. |
contribution of serotonin (5-ht) 5-ht2 receptor subtypes to the discriminative stimulus effects of cocaine in rats. |
2006-01-31 |
2023-08-12 |
rat |
| Malgorzata Filip, Marcy J Bubar, Kathryn A Cunningha. Contribution of serotonin (5-HT) 5-HT2 receptor subtypes to the discriminative stimulus effects of cocaine in rats. Psychopharmacology. vol 183. issue 4. 2006-01-31. PMID:16261316. |
the serotonin (5-hydroxytryptamine; 5-ht) 5-ht2 receptor (5-ht2r) family is an important regulator of the behavioral responsiveness to cocaine. |
2006-01-31 |
2023-08-12 |
rat |
| Gennady A Buznikov, Robert E Peterson, Lyudmila A Nikitina, Vladimir V Bezuglov, Jean M Laude. The pre-nervous serotonergic system of developing sea urchin embryos and larvae: pharmacologic and immunocytochemical evidence. Neurochemical research. vol 30. issue 6-7. 2006-01-30. PMID:16187217. |
some of these substances (agonists of 5-ht1 receptors, antagonists of 5-ht2, 5-ht3 or 5-ht4 receptors, and inhibitors of the serotonin transporter, sert) perturbed post-blastulation development, eliciting changes in embryonic/larval phenotypes typical for each class of receptor ligand. |
2006-01-30 |
2023-08-12 |
Not clear |
| Satoshi Matsusaka, Ichiro Wakabayash. 5-Hydroxytryptamine as a potent migration enhancer of human aortic endothelial cells. FEBS letters. vol 579. issue 30. 2006-01-23. PMID:16310780. |
5-ht significantly enhanced migration of human aortic endothelial cells (haecs), and this enhancement was completely inhibited by gr 55562, a 5-ht1 receptor antagonist, and fluoxetine, a 5-ht transporter inhibitor, but was not affected by ketanserin, a 5-ht2 receptor antagonist. |
2006-01-23 |
2023-08-12 |
human |
| J-Ch Glérant, J Khater-Boidin, F Salzmann, B Duro. Vagal pulmonary afferents and central respiratory effects of 5-HT in newborn rats. The European journal of neuroscience. vol 22. issue 9. 2006-01-17. PMID:16262663. |
in decerebrate newborn rats, serotonin (5-ht) is a respiratory depressant via activation of 5-ht2 receptors, whereas it evokes respiratory stimulant effects when applied to the isolated brainstem obtained from the newborn rat. |
2006-01-17 |
2023-08-12 |
rat |
| Boong-Nyun Kim, Chung-Bum Lee, Jun-Won Hwang, Min-Sub Shin, Soo-Churl Ch. Effectiveness and safety of risperidone for children and adolescents with chronic tic or tourette disorders in Korea. Journal of child and adolescent psychopharmacology. vol 15. issue 2. 2006-01-13. PMID:15910216. |
the results of this study show that, risperidone, a potent combined serotonin (5-ht2) and dopamine (d2) receptor antagonist, is both effective and safe for the treatment for tourette's disorder and chronic tic disorder in children and adolescents. |
2006-01-13 |
2023-08-12 |
human |
| E Calama, A V Ortíz de Urbina, A Morán, M L Martín, L San Romá. Effect of 5-hydroxytryptamine on neurogenic vasoconstriction in the isolated, autoperfused hindquarters of the rat. Clinical and experimental pharmacology & physiology. vol 32. issue 10. 2006-01-05. PMID:16173953. |
the effect of 5-ht was inhibited by methiothepin (a non-specific 5-ht receptor antagonist), but not by ritanserin (a selective 5-ht2 receptor antagonist). |
2006-01-05 |
2023-08-12 |
rat |
| E Calama, A V Ortíz de Urbina, A Morán, M L Martín, L San Romá. Effect of 5-hydroxytryptamine on neurogenic vasoconstriction in the isolated, autoperfused hindquarters of the rat. Clinical and experimental pharmacology & physiology. vol 32. issue 10. 2006-01-05. PMID:16173953. |
the effects of 5-ht were mimicked by 5-carboxamidotryptamine (a 5-ht1 receptor agonist) and l-694 247 (a selective 5-ht1d receptor agonist), but not by 8-hydroxy-2-dipropylaminotetralin (a 5-ht1a receptor agonist), cgs-12066b (a 5-ht1b receptor agonist), alpha-methyl-5-ht (a 5-ht2 receptor agonist), 1-(3-chlorophenyl) piperazine (a 5-ht2c receptor agonist) or 1-phenylbiguanide (a 5-ht3 receptor agonist). |
2006-01-05 |
2023-08-12 |
rat |
| Barbara L Shay, Michael Sawchuk, David W Machacek, Shawn Hochma. Serotonin 5-HT2 receptors induce a long-lasting facilitation of spinal reflexes independent of ionotropic receptor activity. Journal of neurophysiology. vol 94. issue 4. 2005-12-30. PMID:16033939. |
serotonin 5-ht2 receptors induce a long-lasting facilitation of spinal reflexes independent of ionotropic receptor activity. |
2005-12-30 |
2023-08-12 |
rat |
| Satoshi Matsusaka, Ichiro Wakabayash. 5-Hydroxytryptamine augments migration of human aortic smooth muscle cells through activation of RhoA and ERK. Biochemical and biophysical research communications. vol 337. issue 3. 2005-12-15. PMID:16219295. |
the enhancing effect of 5-ht on cell migration was markedly inhibited in the presence of ketanserin, a 5-ht2 receptor antagonist, but not by gr 55562, a 5-ht1 receptor antagonist. |
2005-12-15 |
2023-08-12 |
human |
| Satoshi Matsusaka, Ichiro Wakabayash. 5-Hydroxytryptamine augments migration of human aortic smooth muscle cells through activation of RhoA and ERK. Biochemical and biophysical research communications. vol 337. issue 3. 2005-12-15. PMID:16219295. |
thus, 5-ht has a potent enhancing action on migration of hasmcs due to an increase in stress fiber formation by 5-ht2 receptor stimulation followed by activation of the rho-kinase and erk pathways. |
2005-12-15 |
2023-08-12 |
human |
| Mostafa El Mansari, Pierre Blie. Responsiveness of 5-HT(1A) and 5-HT2 receptors in the rat orbitofrontal cortex after long-term serotonin reuptake inhibition. Journal of psychiatry & neuroscience : JPN. vol 30. issue 4. 2005-11-15. PMID:16049570. |
responsiveness of 5-ht(1a) and 5-ht2 receptors in the rat orbitofrontal cortex after long-term serotonin reuptake inhibition. |
2005-11-15 |
2023-08-12 |
rat |
| Theodore A Slotkin, Frederic J Seidle. The alterations in CNS serotonergic mechanisms caused by neonatal chlorpyrifos exposure are permanent. Brain research. Developmental brain research. vol 158. issue 1-2. 2005-10-27. PMID:16024092. |
to determine if these changes are permanent, we administered 1 mg/kg of cpf daily to neonatal rats on postnatal days 1-4, a regimen devoid of systemic toxicity, and examined 5ht synaptic markers at 5 months of age: radioligand binding to 5ht1a and 5ht2 receptors and to the 5ht transporter. |
2005-10-27 |
2023-08-12 |
rat |