| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Thomas Hussenether, Harald Hübner, Peter Gmeiner, Reinhard Troschüt. Clozapine derived 2,3-dihydro-1H-1,4- and 1,5-benzodiazepines with D4 receptor selectivity: synthesis and biological testing. Bioorganic & medicinal chemistry. vol 12. issue 10. 2004-12-10. PMID:15110844. |
for the most promising compounds, intrinsic activity and binding properties to serotonin 5-ht1a and 5-ht2 were also determined. |
2004-12-10 |
2023-08-12 |
Not clear |
| Thomas I F H Cremers, Marco Giorgetti, Fokko J Bosker, Sandra Hogg, Jørn Arnt, Arne Mørk, Gerard Honig, Klaus-Peter Bøgesø, Ben H C Westerink, Hans den Boer, Håkan V Wikstrom, Laurence H Tecot. Inactivation of 5-HT(2C) receptors potentiates consequences of serotonin reuptake blockade. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 29. issue 10. 2004-11-22. PMID:15138437. |
using in vivo microdialysis methods in rats, the nonselective 5-ht2 receptor antagonist ketanserin was observed to produce a robust augmentation of citalopram-, fluoxetine-, and sertraline-induced elevations of hippocampal extracellular serotonin levels. |
2004-11-22 |
2023-08-12 |
mouse |
| Malgorzata Filip, Marcy J Bubar, Kathryn A Cunningha. Contribution of serotonin (5-hydroxytryptamine; 5-HT) 5-HT2 receptor subtypes to the hyperlocomotor effects of cocaine: acute and chronic pharmacological analyses. The Journal of pharmacology and experimental therapeutics. vol 310. issue 3. 2004-11-01. PMID:15131246. |
contribution of serotonin (5-hydroxytryptamine; 5-ht) 5-ht2 receptor subtypes to the hyperlocomotor effects of cocaine: acute and chronic pharmacological analyses. |
2004-11-01 |
2023-08-12 |
rat |
| Malgorzata Filip, Marcy J Bubar, Kathryn A Cunningha. Contribution of serotonin (5-hydroxytryptamine; 5-HT) 5-HT2 receptor subtypes to the hyperlocomotor effects of cocaine: acute and chronic pharmacological analyses. The Journal of pharmacology and experimental therapeutics. vol 310. issue 3. 2004-11-01. PMID:15131246. |
the role of serotonin (5-hydroxytryptamine; 5-ht) 5-ht2 receptor subtypes (5-ht2ar, 5-ht2br, and 5-ht2cr) in acute cocaine-evoked hyperactivity was compared with their contribution to the development and expression of locomotor sensitization upon repeated, intermittent treatment with cocaine (10 mg/kg/day for 5 days) in male wistar rats. |
2004-11-01 |
2023-08-12 |
rat |
| A S Pivovarov, V L Nistratov. Modulatory serotonin receptors on the soma of command neurons in edible snail. Bulletin of experimental biology and medicine. vol 136. issue 2. 2004-10-22. PMID:14631485. |
by contrast, ly-53.857, ics-205.930, and sdz-205.557, antagonists of 5-ht2, 5-ht3, and 5-ht4 serotonin receptors, respectively, produced no effect on the modulatory effect of serotonin. |
2004-10-22 |
2023-08-12 |
Not clear |
| Beata Kopczyńska, Małgorzata Szereda-Przestaszewsk. 5HT2 and 5HT3 receptors' contribution to modeling of post-serotonin respiratory pattern in cats. Life sciences. vol 75. issue 19. 2004-10-04. PMID:15350826. |
cardio-respiratory reflex effects of an exogenous serotonin challenge are suggested to be modulated by activation of the peripheral 5ht2 and 5ht3 receptors. |
2004-10-04 |
2023-08-12 |
rat |
| Arlene N James, James P Ryan, Michael D Crowell, Henry P Parkma. Regional gastric contractility alterations in a diabetic gastroparesis mouse model: effects of cholinergic and serotoninergic stimulation. American journal of physiology. Gastrointestinal and liver physiology. vol 287. issue 3. 2004-09-17. PMID:15107299. |
serotonin's contractile effect is mediated, in part, through muscarinic, 5-ht2, and 5-ht4 receptors. |
2004-09-17 |
2023-08-12 |
mouse |
| Stefan Leuch. Amisulpride a selective dopamine antagonist and atypical antipsychotic: results of a meta-analysis of randomized controlled trials. The international journal of neuropsychopharmacology. vol 7 Suppl 1. 2004-09-14. PMID:14972080. |
the pharmacological profiles of the atypical antipsychotics, clozapine, olanzapine, quetiapine and risperidone, all show a combined serotonin (5-ht2) and dopamine type-2 (d2) receptor antagonism. |
2004-09-14 |
2023-08-12 |
Not clear |
| Angela B Lang. A neurohormonal role for serotonin in the control of locust oviducts. Archives of insect biochemistry and physiology. vol 56. issue 4. 2004-09-09. PMID:15274179. |
vertebrate type serotonin agonists and antagonists were used and the profile shows that the receptors on the non-innervated and innervated portion of the oviducts are more similar to 5-ht3 receptors than to either 5-ht1 or 5-ht2 receptors. |
2004-09-09 |
2023-08-12 |
Not clear |
| Vitali A Bouryi, David I Lewi. The modulation by 5-HT of glutamatergic inputs from the raphe pallidus to rat hypoglossal motoneurones, in vitro. The Journal of physiology. vol 553. issue Pt 3. 2004-08-31. PMID:14555716. |
whilst 5-ht has a direct excitatory action on hypoglossal motoneurones as a result of activation of 5-ht2 receptors, microinjection of 5-ht2 antagonists into the hypoglossal nucleus reduces motor activity to a much lesser extent compared to the suppression observed during sleep suggesting other transmitters co-localised in caudal raphe neurones may also be involved. |
2004-08-31 |
2023-08-12 |
rat |
| Vitali A Bouryi, David I Lewi. The modulation by 5-HT of glutamatergic inputs from the raphe pallidus to rat hypoglossal motoneurones, in vitro. The Journal of physiology. vol 553. issue Pt 3. 2004-08-31. PMID:14555716. |
5-ht evoked a direct membrane depolarisation (8.45 +/- 3.8 mv, p < 0.001) and increase in cell input resistance (53 +/- 40 %, p < 0.001) which was blocked by the 5-ht2 antagonist, ritanserin (2.40 +/- 2.7 vs. 7.04 +/- 4.6 mv). |
2004-08-31 |
2023-08-12 |
rat |
| Elsa Maria Gouveia, Celso Rodrigues Franc. Involvement of serotonin 5HT1 and 5HT2 receptors and nitric oxide synthase in the medial preoptic area on gonadotropin secretion. Brain research bulletin. vol 63. issue 3. 2004-07-15. PMID:15145143. |
involvement of serotonin 5ht1 and 5ht2 receptors and nitric oxide synthase in the medial preoptic area on gonadotropin secretion. |
2004-07-15 |
2023-08-12 |
rat |
| Claudia Regina Monassi, Leda Menescal-de-Oliveir. Serotonin 5-HT2 and 5-HT1A receptors in the periaqueductal gray matter differentially modulate tonic immobility in guinea pig. Brain research. vol 1009. issue 1-2. 2004-07-12. PMID:15120594. |
serotonin 5-ht2 and 5-ht1a receptors in the periaqueductal gray matter differentially modulate tonic immobility in guinea pig. |
2004-07-12 |
2023-08-12 |
Not clear |
| David S Paterson, Richard A Belliveau, Felicia Trachtenberg, Hannah C Kinne. Differential development of 5-HT receptor and the serotonin transporter binding in the human infant medulla. The Journal of comparative neurology. vol 472. issue 2. 2004-07-01. PMID:15048689. |
tissue receptor autoradiography with 3h-lysergic acid diethylamide (3h-lsd), 3h-8-hydroxy-2-[di-n-propylamine] tetralin (3h-8-oh-dpat), and 125i-rti-55 was used to map the distribution and developmental profile of 5-ht(1a-1d) and 5-ht2 receptors, 5-ht1a receptors, and the serotonin (5-ht) transporter (sert), respectively, to nuclei with cardiorespiratory function in the human medulla from midgestation to maturity. |
2004-07-01 |
2023-08-12 |
human |
| Merry C Clark, Timothy E Dever, John J Dever, Ping Xu, Vincent Rehder, Maria A Sosa, Deborah J Bar. Arthropod 5-HT2 receptors: a neurohormonal receptor in decapod crustaceans that displays agonist independent activity resulting from an evolutionary alteration to the DRY motif. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 13. 2004-06-18. PMID:15056722. |
this receptor is most homologous to the 5-ht2 subtype and shows a dose-dependent response to 5-ht but not to any of the other monoamines present in the stns. |
2004-06-18 |
2023-08-12 |
lobster |
| Elaine Sanders-Bush, Hugh Fentress, Lisa Hazelwoo. Serotonin 5-ht2 receptors: molecular and genomic diversity. Molecular interventions. vol 3. issue 6. 2004-06-10. PMID:14993464. |
serotonin 5-ht2 receptors: molecular and genomic diversity. |
2004-06-10 |
2023-08-12 |
Not clear |
| Mary M Niblock, Hannah C Kinney, Catherine J Luce, Richard A Belliveau, James J Filian. The development of the medullary serotonergic system in the piglet. Autonomic neuroscience : basic & clinical. vol 110. issue 2. 2004-06-08. PMID:15046730. |
tritiated (3h)-lysergic acid diethylamide (lsd) binding to 5-ht1a-d and 5-ht2 receptors and 3h-8-hydroxy-2-[di-n-propylamine]tetralin (8-oh-dpat) binding to 5-ht1a receptors were used to quantify and map the distribution of these serotonin receptors between 4 and 60 postnatal days. |
2004-06-08 |
2023-08-12 |
human |
| David Mamo, Shitij Kapur, C M Shammi, George Papatheodorou, Steve Mann, François Therrien, Gary Remingto. A PET study of dopamine D2 and serotonin 5-HT2 receptor occupancy in patients with schizophrenia treated with therapeutic doses of ziprasidone. The American journal of psychiatry. vol 161. issue 5. 2004-06-03. PMID:15121646. |
a pet study of dopamine d2 and serotonin 5-ht2 receptor occupancy in patients with schizophrenia treated with therapeutic doses of ziprasidone. |
2004-06-03 |
2023-08-12 |
Not clear |
| Thomas Ladewig, Peter M Lalley, Bernhard U Kelle. Serotonergic modulation of intracellular calcium dynamics in neonatal hypoglossal motoneurons from mouse. Brain research. vol 1001. issue 1-2. 2004-05-28. PMID:14972649. |
(3) the 5ht2 receptor agonist alpha-methyl-5ht (25, 50 microm) had effects on membrane potential, discharge properties and [ca]i that were identical to those observed for 5ht, whereas the 5ht3 receptor agonist 1-(m-chlorophenyl) biguanide (50 microm) had no effect on membrane properties or intracellular calcium levels. |
2004-05-28 |
2023-08-12 |
mouse |
| J E Olijslagers, T R Werkman, A C McCreary, R Siarey, C G Kruse, W J Wadma. 5-HT2 receptors differentially modulate dopamine-mediated auto-inhibition in A9 and A10 midbrain areas of the rat. Neuropharmacology. vol 46. issue 4. 2004-05-28. PMID:14975674. |
the involvement of 5-ht and specific 5-ht2 receptors in augmentation of auto-inhibition in a10 could have important implications for our understanding of the mechanism of atypical antipsychotic drug action. |
2004-05-28 |
2023-08-12 |
rat |