| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nicholas Zareifopoulos, Maria Lagadinou, Anastasia Karela, Ourania Kyriakopoulou, Dimitrios Velissari. Neuropsychiatric Effects of Antiviral Drugs. Cureus. vol 12. issue 8. 2020-09-28. PMID:32905132. |
notable examples include oseltamivir which may act as mao inhibitor and efavirenz, which has an affinity for serotonin 5-ht2 and gaba-a receptors, the serotonin transporter, the mao enzyme, and the vesicular monoamine transporter, with subjective effects which may be similar to those of the psychedelic hallucinogen lysergic acid diethylamide (lsd). |
2020-09-28 |
2023-08-13 |
human |
| Víctor Cervantes-Ramírez, Martha Canto-Bustos, Diana Aguilar-Magaña, Elsy Arlene Pérez-Padilla, José Luis Góngora-Alfaro, Juan Carlos Pineda, Marco Atzori, Humberto Salgad. Citalopram reduces glutamatergic synaptic transmission in the auditory cortex via activation of 5-HT1A receptors. Neuroreport. vol 30. issue 18. 2020-07-31. PMID:31714483. |
here, we characterize the modulation of excitatory post-synaptic currents by application of either 5-ht or agonists of 5-ht1a and 5-ht2 receptors, or by endogenous 5-ht evoked by citalopram on pyramidal neurons from layer ii/iii of rat auditory cortex. |
2020-07-31 |
2023-08-13 |
rat |
| Víctor Cervantes-Ramírez, Martha Canto-Bustos, Diana Aguilar-Magaña, Elsy Arlene Pérez-Padilla, José Luis Góngora-Alfaro, Juan Carlos Pineda, Marco Atzori, Humberto Salgad. Citalopram reduces glutamatergic synaptic transmission in the auditory cortex via activation of 5-HT1A receptors. Neuroreport. vol 30. issue 18. 2020-07-31. PMID:31714483. |
we observed that selective agonists of 5-ht1a and 5-ht2 receptors [8-oh-dpat (10 µm) and doi (10 µm), respectively] mimic the effect of 5-ht on the excitatory post-synaptic currents. |
2020-07-31 |
2023-08-13 |
rat |
| Louise Mulcahy, Elizabeth Tudor, Simon R Baile. Validation of canine uterine and testicular arteries for the functional characterisation of receptor-mediated contraction as a replacement for laboratory animal tissues in teaching. PloS one. vol 15. issue 5. 2020-07-23. PMID:32453770. |
the response to serotonin (5-ht) receptor agonists were also investigated, including 5-ht (acting at both 5-ht1 and 5-ht2 receptors), 5-carboxamidotryptamine (5-ct; 5-ht1 selective) and α-methyl 5-ht (5-ht2 selective). |
2020-07-23 |
2023-08-13 |
Not clear |
| Louise Mulcahy, Elizabeth Tudor, Simon R Baile. Validation of canine uterine and testicular arteries for the functional characterisation of receptor-mediated contraction as a replacement for laboratory animal tissues in teaching. PloS one. vol 15. issue 5. 2020-07-23. PMID:32453770. |
in the testicular artery, the 5-ht2 receptor selective agonist, α-methyl 5-ht, produced a similar contractile response to 5-ht but the administration of 5-ct failed to produce a response in either the testicular or uterine artery segments. |
2020-07-23 |
2023-08-13 |
Not clear |
| Cheryl Brandenburg, Gene J Blat. Differential serotonin transporter (5-HTT) and 5-HT Journal of neurochemistry. vol 151. issue 5. 2020-06-15. PMID:31325179. |
specific binding to the 5-ht transporter (5-htt) as well as to 5-ht2 and 1a receptors (5-ht₂, 5-ht |
2020-06-15 |
2023-08-13 |
Not clear |
| Aruna Sharma, Rudy J Castellani, Mark A Smith, Dafin Fior Muresanu, Prasanta Kumar Dey, Hari Shanker Sharm. 5-Hydroxytryptophan: A precursor of serotonin influences regional blood-brain barrier breakdown, cerebral blood flow, brain edema formation, and neuropathology. International review of neurobiology. vol 146. 2020-02-03. PMID:31349924. |
in addition, several neurochemical agents such as p-cpa (5-ht synthesis inhibitor) indomethacin (prostaglandin synthase inhibitor), diazepam (ant stress drug), cyproheptadine, ketanserin (5-ht2 receptor antagonists) and vinblastine (inhibitor of microtubule function) were examined on 5-ht neurotoxicity. |
2020-02-03 |
2023-08-13 |
rat |
| Dugovi. Functional activity of 5-HT2 receptors in the modulation of the sleep/wakefulness states. Journal of sleep research. vol 1. issue 3. 2019-11-20. PMID:10607046. |
data obtained from animals and from clinical studies suggest that serotonin may exert an inhibitory control on deep slow-wave sleep (sws) through 5-ht2 receptors. |
2019-11-20 |
2023-08-12 |
Not clear |
| Young-Chul Chung, Hong-Bai Eu. Hyperprolactinaemia induced by risperidone. The international journal of neuropsychopharmacology. vol 1. issue 1. 2019-11-20. PMID:11281951. |
risperidone is a potent antagonist of both dopamine (d2) and serotonin (5-ht2) receptors, demonstrating improvement of both positive and negative symptoms and a lower propensity for inducing extrapyramidal symptoms (eps) than typical neuroleptics. |
2019-11-20 |
2023-08-12 |
Not clear |
| P P Fong, R Deguchi, K Kyozuk. Serotonergic Ligands Induce Spawning but not Oocyte Maturation in the Bivalve Mactra chinensis from Central Japan. The Biological bulletin. vol 191. issue 1. 2019-11-20. PMID:29220216. |
the vertebrate 5-ht2 receptor agonist alpha-methyl 5-ht and the selective 5ht1a agonist 8-oh-dpat were also effective at inducing spawning. |
2019-11-20 |
2023-08-13 |
Not clear |
| Kyeong Seop Kim, Mi Ae Kim, Young Chang Soh. Molecular characterization, expression analysis, and functional properties of multiple 5-hydroxytryptamine receptors in Pacific abalone (Haliotis discus hannai). General and comparative endocrinology. vol 276. 2019-05-17. PMID:30849410. |
a phylogenetic analysis indicated that the molluskan 5-ht receptors are largely classified into four major clades: 5-ht1/5/7, 5-ht2, 5-ht4, and 5-ht6. |
2019-05-17 |
2023-08-13 |
Not clear |
| Philippa M Warren, Stephanie C Steiger, Thomas E Dick, Peter M MacFarlane, Warren J Alilain, Jerry Silve. Rapid and robust restoration of breathing long after spinal cord injury. Nature communications. vol 9. issue 1. 2018-12-31. PMID:30482901. |
however, in a sub-population of animals, this combination treatment caused excess serotonergic (5ht) axon sprouting leading to aberrant tonic activity in the diaphragm that could be mitigated via 5ht2 receptor blockade. |
2018-12-31 |
2023-08-13 |
rat |
| Jose Luis Cortes-Altamirano, Adriana Olmos-Hernandez, Herlinda Bonilla Jaime, Paul Carrillo-Mora, Cindy Bandala, Samuel Reyes-Long, Alfonso Alfaro-Rodrígue. Review: 5-HT1, 5-HT2, 5-HT3 and 5-HT7 Receptors and their Role in the Modulation of Pain Response in the Central Nervous System. Current neuropharmacology. vol 16. issue 2. 2018-10-01. PMID:28901281. |
on the other hand, several researches reported that serotonin modulates nociceptive response through 5-ht1, 5-ht2, 5-ht3, and 5-ht7 receptors in the central nervous system (cns). |
2018-10-01 |
2023-08-13 |
Not clear |
| Jihua Fu, Chen Li, Guangli Zhang, Xin Tong, Haiwei Zhang, Jie Ding, Yingying Ma, Ru Cheng, Shanshan Hou, Shanshan An, Xin Li, Shaoxin M. Crucial Roles of 5-HT and 5-HT2 Receptor in Diabetes-Related Lipid Accumulation and Pro-Inflammatory Cytokine Generation in Hepatocytes. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. vol 48. issue 6. 2018-09-10. PMID:30121645. |
crucial roles of 5-ht and 5-ht2 receptor in diabetes-related lipid accumulation and pro-inflammatory cytokine generation in hepatocytes. |
2018-09-10 |
2023-08-13 |
Not clear |
| Jihua Fu, Chen Li, Guangli Zhang, Xin Tong, Haiwei Zhang, Jie Ding, Yingying Ma, Ru Cheng, Shanshan Hou, Shanshan An, Xin Li, Shaoxin M. Crucial Roles of 5-HT and 5-HT2 Receptor in Diabetes-Related Lipid Accumulation and Pro-Inflammatory Cytokine Generation in Hepatocytes. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. vol 48. issue 6. 2018-09-10. PMID:30121645. |
previously, we confirmed that liver-synthesized 5-ht rather than non-liver 5-ht, acting on the 5-ht2 receptor (5-ht2r), modulates lipid-induced excessive lipid synthesis (els). |
2018-09-10 |
2023-08-13 |
Not clear |
| Claudia Vignali, Angelo Groppi, Francesca Brandolini, Francesco Maria Avato, Anna Talarico, Rosa Maria Gaudio, Luca Morin. Mirtazapine fatal poisoning. Forensic science international. vol 276. 2018-06-06. PMID:28535979. |
mirtazapine is a noradrenergic and specific serotoninergic antidepressant agent that stimulates norepinephrine and serotonin release while also blocking serotonin receptors (5-ht2 and 5-ht3). |
2018-06-06 |
2023-08-13 |
Not clear |
| Isabella Salzer, Enkhbileg Gantumur, Arsalan Yousuf, Stefan Boeh. Control of sensory neuron excitability by serotonin involves 5HT2C receptors and Ca(2+)-activated chloride channels. Neuropharmacology. vol 110. issue Pt A. 2018-02-22. PMID:27511837. |
in 58% of the neurons tested, 5ht increased action potential firing, an effect that was abolished by the 5ht2 receptor antagonist ritanserin, but not by the 5ht3 antagonist tropisetron. |
2018-02-22 |
2023-08-13 |
rat |
| Isabella Salzer, Enkhbileg Gantumur, Arsalan Yousuf, Stefan Boeh. Control of sensory neuron excitability by serotonin involves 5HT2C receptors and Ca(2+)-activated chloride channels. Neuropharmacology. vol 110. issue Pt A. 2018-02-22. PMID:27511837. |
amongst the subtype selective 5ht2 antagonists, only rs 102221 (5ht2c-selectively) counteracted the rise in action potential firing elicited by 5ht. |
2018-02-22 |
2023-08-13 |
rat |
| Tobias Buchborn, Helmut Schröder, Volker Höllt, Gisela Grecksc. Repeated lysergic acid diethylamide in an animal model of depression: Normalisation of learning behaviour and hippocampal serotonin 5-HT2 signalling. Journal of psychopharmacology (Oxford, England). vol 28. issue 6. 2018-01-16. PMID:24785760. |
repeated lysergic acid diethylamide in an animal model of depression: normalisation of learning behaviour and hippocampal serotonin 5-ht2 signalling. |
2018-01-16 |
2023-08-13 |
rat |
| b' Ewa Poleszak, Weronika Stasiuk, Aleksandra Szopa, El\\xc5\\xbcbieta Wyska, Anna Serefko, Anna Oniszczuk, Sylwia Wo\\xc5\\x9bko, Katarzyna \\xc5\\x9awi\\xc4\\x85der, Piotr Wla\\xc5\\xb. Traxoprodil, a selective antagonist of the NR2B subunit of the NMDA receptor, potentiates the antidepressant-like effects of certain antidepressant drugs in the forced swim test in mice. Metabolic brain disease. vol 31. issue 4. 2018-01-12. PMID:26924124.' |
serotonergic lesion and experiment using the selective agonists of serotonin receptors 5-ht1a and 5-ht2 was conducted to evaluate the role of the serotonergic system in the antidepressant action of traxoprodil. |
2018-01-12 |
2023-08-13 |
mouse |