All Relations between 5-ht receptor 2 and serotonin

Publication Sentence Publish Date Extraction Date Species
J Yamada, Y Sugimoto, M Ohkura, K Inou. Effects of the 5-HT2 receptor antagonist, ritanserin on hyperthermia and depletion of 5-HT in frontal cortex induced by a 5-HT releasing drug, p-chloroamphetamine (PCA) in mice. Biological & pharmaceutical bulletin. vol 24. issue 10. 2002-03-19. PMID:11642332. effects of the 5-ht2 receptor antagonist, ritanserin on hyperthermia and depletion of 5-ht induced by the 5-ht-releasing drug, p-chloroamphetamine (pca) were investigated. 2002-03-19 2023-08-12 mouse
N H Prins, L M Akkermans, R A Lefebvre, J A Schuurke. Characterization of the receptors involved in the 5-HT-induced excitation of canine antral longitudinal muscle. British journal of pharmacology. vol 134. issue 6. 2002-03-15. PMID:11704657. there were non-significant trends of the selective 5-ht3 receptor antagonist granisetron (1 microm), and methysergide (1 microm; preventing interactions of 5-ht with 5-ht1, 5-ht2, 5-ht5, 5-ht6 and 5-ht7 receptors) to increase the response to 5-ht. 2002-03-15 2023-08-12 dog
R L Cooper, R J Chase, J Tabo. Altered responsiveness to 5-HT at the crayfish neuromuscular junction due to chronic p-CPA and m-CPP treatment. Brain research. vol 916. issue 1-2. 2002-01-14. PMID:11597601. injections of the 5-ht1 and 5-ht2 vertebrate receptor agonist, 1-(3-chlorophenyl) piperazine dihydrochloride (m-cpp), for 1 week resulted in a decreased responsiveness to application of 5-ht. 2002-01-14 2023-08-12 Not clear
V G Kolpakov, T A Alekhina, N N Barykina, V F Chugui, N K Popov. Some physiological manifestations of the activity of the gene controlling the predisposition to pendulum-like movements in rats. Neuroscience and behavioral physiology. vol 31. issue 3. 2001-12-04. PMID:11430576. the physiological actions of the gene controlling the predisposition to stereotypic hyperkinesia in the form of pendulum-like movements (pm) and, probably, a form of spontaneous nystagmus in rats with albinism are manifest as a number of behavioral characteristics (total motor activity, emotionality, startle reflex intensity, sensitivity to serotonin 5-ht2 receptors as assessed in terms of the intensity of head twitching, and predisposition to cataleptic responses). 2001-12-04 2023-08-12 rat
B Bobula, A Zahorodna, M Bija. Different receptor subtypes are involved in the serotonin-induced modulation of epileptiform activity in rat frontal cortex in vitro. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 52. issue 2. 2001-12-04. PMID:11453105. the excitatory action of 5-ht, which predominates, is mediated mainly by 5-ht2 receptors. 2001-12-04 2023-08-12 rat
M D Waldinger, A H Zwinderman, B Olivie. Antidepressants and ejaculation: a double-blind, randomized, placebo-controlled, fixed-dose study with paroxetine, sertraline, and nefazodone. Journal of clinical psychopharmacology. vol 21. issue 3. 2001-11-01. PMID:11386492. a double-blind, placebo-controlled study in men with lifelong rapid ejaculation was performed to assess the effects of two selective serotonin (5-ht) reuptake inhibitors--paroxetine and sertraline--and the 5-ht2 antagonist and 5-ht/noradrenaline reuptake inhibitor nefazodone on the latency to ejaculate. 2001-11-01 2023-08-12 Not clear
L D Sanford, W K Hunt, R J Ross, A I Pack, A R Morriso. Central administration of a 5-HT2 receptor agonist and antagonist: lack of effect on rapid eye movement sleep and pgo waves. Sleep research online : SRO. vol 1. issue 2. 2001-10-18. PMID:11382861. we microinfused the relatively specific 5-ht2 agonist, doi (1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane), the relatively specific 5-ht2 antagonist, ketanserin, and the nonspecific 5-ht antagonist, methysergide, locally into the peribrachial region of ppt in cats and monitored behavioral state and pgo waves. 2001-10-18 2023-08-12 rat
L D Sanford, W K Hunt, R J Ross, A I Pack, A R Morriso. Central administration of a 5-HT2 receptor agonist and antagonist: lack of effect on rapid eye movement sleep and pgo waves. Sleep research online : SRO. vol 1. issue 2. 2001-10-18. PMID:11382861. these results suggest that 5-ht2 receptors associated with cholinergic cells are minimally involved in the control of behavioral state and, together with the recent findings of others, suggest that 5-ht may not modulate pgo wave generation via direct action on cholinergic neurons in ppt/ldt, a departure from the long-held but minimally-tested view. 2001-10-18 2023-08-12 rat
M Matsumoto, M Yoshiok. [Intracellular signal transduction mediated via 5-HT and NA receptors]. Nihon rinsho. Japanese journal of clinical medicine. vol 59. issue 8. 2001-10-18. PMID:11519141. these pathways are elevated via 5-ht and/or na receptors which directly couple to the camp system(5-ht4,6,7 receptors or beta adrenoceptors), or via receptors that lead to activation of ca(2+)-dependent protein kinase(5-ht2 receptors or alpha 1 adrenoceptors). 2001-10-18 2023-08-12 Not clear
P Retama. [Antidepressant psychopharmacotherapy]. Revista medica de Chile. vol 129. issue 7. 2001-10-18. PMID:11552452. tricyclics, non selective mao inhibitors, reversible mao inhibitors, selective serotonin reuptake inhibitors, dopamine and noradrenalin reuptake inhibitors, 5-ht2 blockers with serotonin reuptake blocking effect, serotonin, noradrenalin and dopamine reuptake inhibitors, alfa 2 receptor blockers and 5-ht/2-3 inhibitors are the eight available types of antidepressants. 2001-10-18 2023-08-12 Not clear
S P Vickers, C T Dourish, G A Kennet. Evidence that hypophagia induced by d-fenfluramine and d-norfenfluramine in the rat is mediated by 5-HT2C receptors. Neuropharmacology. vol 41. issue 2. 2001-10-11. PMID:11489456. the present series of studies is the first to investigate the pharmacological mechanisms underlying d-fenfluramine- and d-norfenfluramine-induced hypophagia in the rat using highly selective serotonin 5-ht2 receptor antagonists. 2001-10-11 2023-08-12 rat
R Larisch, A Klimke, F Mayoral, K Hamacher, H R Herzog, H Vosberg, M Tosch, W Gaebel, F Rivas, H H Coenen, H W Müller-Gärtne. Disturbance of serotonin 5HT2 receptors in remitted patients suffering from hereditary depressive disorder. Nuklearmedizin. Nuclear medicine. vol 40. issue 4. 2001-10-11. PMID:11556203. disturbance of serotonin 5ht2 receptors in remitted patients suffering from hereditary depressive disorder. 2001-10-11 2023-08-12 Not clear
T Watanabe, R Pakala, T Katagiri, C R Benedic. Lipid peroxidation product 4-hydroxy-2-nonenal acts synergistically with serotonin in inducing vascular smooth muscle cell proliferation. Atherosclerosis. vol 155. issue 1. 2001-05-10. PMID:11223424. a 5-ht2 receptor antagonist ly 281067 (10 microg/ml) and pertussis toxin (10 ng/ml) inhibited the mitogenic effect of 5-ht only. 2001-05-10 2023-08-12 rabbit
E M Chapin, R Andrad. A 5-HT(7) receptor-mediated depolarization in the anterodorsal thalamus. I. Pharmacological characterization. The Journal of pharmacology and experimental therapeutics. vol 297. issue 1. 2001-05-03. PMID:11259568. we found that the 5-ht1 and 5-ht7 agonists 5-carboxamidotryptamine (5-ct) and 5-methoxytryptamine mimicked the response to 5-ht, whereas the 5-ht2 agonist 2,5-dimethoxy-4-iodoamphetamine did not. 2001-05-03 2023-08-12 Not clear
S Kapur, G Remingto. Atypical antipsychotics: new directions and new challenges in the treatment of schizophrenia. Annual review of medicine. vol 52. 2001-04-26. PMID:11160792. however, a preferential action on serotonin 5-ht2 or d4 receptors, or a more rapid dissociation from the dopamine d2 receptor, may account for atypicality. 2001-04-26 2023-08-12 Not clear
T Wetterlin. Bodyweight gain with atypical antipsychotics. A comparative review. Drug safety. vol 24. issue 1. 2001-04-19. PMID:11219487. the relative receptor affinities of the atypical antipsychotics for histamine h1 receptors as well as the ratio of their affinity for serotonin 5-ht2 and dopamine d2 receptors appear to be the most robust correlate of bodyweight gain. 2001-04-19 2023-08-12 Not clear
V K Bhargava, L Sah. Serotonergic mechanism in imipramine induced antinociception in rat tail flick test. Indian journal of physiology and pharmacology. vol 45. issue 1. 2001-04-12. PMID:11211562. therefore, we explored the effect of serotonergic system on imipramine induced antinociception by using 5-hydroxytryptamine-3 (5ht3) receptor antagonist ondansetron and 5-hydroxytryptamine-2 (5ht2) receptor antagonist mianserine, and depletion of brain 5-hydroxytryptamine (5ht) with p-chlorophenyl alanine (pcpa). 2001-04-12 2023-08-12 human
P Blier, F V Abbot. Putative mechanisms of action of antidepressant drugs in affective and anxiety disorders and pain. Journal of psychiatry & neuroscience : JPN. vol 26. issue 1. 2001-03-15. PMID:11212592. in major depression, an increase in 5-ht1a transmission is thought to be a crucial determinant of the antidepressant response, whereas an enhancement of 5-ht2 transmission in the orbitofrontal cortex may mediate the therapeutic effect of 5-ht reuptake inhibitors in obsessive-compulsive disorder (ocd). 2001-03-15 2023-08-12 Not clear
R Ramasubbu, A Ravindran, Y Lapierr. Serotonin and dopamine antagonism in obsessive-compulsive disorder: effect of atypical antipsychotic drugs. Pharmacopsychiatry. vol 33. issue 6. 2001-03-08. PMID:11147933. given their higher affinity for serotonin 5ht2 receptors than dopamine d2 receptors, it has been speculated that atypical antipsychotics may induce obsessive-compulsive (oc) symptoms, even at low doses, due to high 5ht2 antagonism, whereas improvement in oc symptoms is thought to occur only at high doses due to high d2 antagonism. 2001-03-08 2023-08-12 Not clear
V Contesse, H Lefebvre, S Lenglet, J M Kuhn, C Delarue, H Vaudr. Role of 5-HT in the regulation of the brain-pituitary-adrenal axis: effects of 5-HT on adrenocortical cells. Canadian journal of physiology and pharmacology. vol 78. issue 12. 2001-03-01. PMID:11149386. 5-ht, acting through 5-ht2 receptors, can also trigger the renin-angiotensin system by stimulating renin secretion and consequently can enhance aldosterone production. 2001-03-01 2023-08-12 mouse