All Relations between 5-ht receptor 2 and serotonin

Publication Sentence Publish Date Extraction Date Species
Y Komats. GABAB receptors, monoamine receptors, and postsynaptic inositol trisphosphate-induced Ca2+ release are involved in the induction of long-term potentiation at visual cortical inhibitory synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 16. issue 20. 1996-11-27. PMID:8815913. accordingly, i examined the involvement of these and other amine receptors, including histamine h1, muscarinic acetylcholine, and serotonin 5-ht2 receptors, all of which are coupled to ip3 formation. 1996-11-27 2023-08-12 rat
Y Komats. GABAB receptors, monoamine receptors, and postsynaptic inositol trisphosphate-induced Ca2+ release are involved in the induction of long-term potentiation at visual cortical inhibitory synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 16. issue 20. 1996-11-27. PMID:8815913. only the blockade of alpha 1 adrenoceptors or serotonin 5-ht2 receptors prevented ltp induction in most, but not all, of the cells. 1996-11-27 2023-08-12 rat
C Comoy, C Marot, T Podona, M L Baudin, L Morin-Allory, G Guillaumet, B Pfeiffer, D H Caignard, P Renard, M C Rettori, G Adam, B Guardiola-Lemaitr. 3-amino-3,4-dihydro-2H-1-benzopyran derivatives as 5-HT1A receptor ligands and potential anxiolytic agents. 2. Synthesis and quantitative structure-activity relationship studies of spiro[pyrrolidine- and piperidine-2,3'(2'H)-benzopyrans]. Journal of medicinal chemistry. vol 39. issue 21. 1996-11-25. PMID:8863806. affinities for the 5-ht1a receptors were in the nanomolar range for the best compounds ((+)-11a,23) with a high selectivity versus other 5-ht (5-ht1b, 5-ht2, 5-ht3) or dopamine (d1, d2) receptor subtypes. 1996-11-25 2023-08-12 Not clear
T Lundberg, L Lindström, P Hartvig, L Reibring, H Agren, H Lundqvist, K J Fasth, G Antoni, B Långströ. Serotonin-2 and dopamine-1 binding components of clozapine in frontal cortex and striatum in the human brain visualized by positron emission tomography. Psychiatry research. vol 67. issue 1. 1996-11-22. PMID:8797237. these results support previous findings that clozapine has affinity for both dopamine d1 and serotonin 5-ht2 receptors in the human frontal cortex. 1996-11-22 2023-08-12 human
C J Watkins, N R Newberr. Multiple 5-HT receptors in the guinea-pig superior cervical ganglion. British journal of pharmacology. vol 117. issue 1. 1996-11-22. PMID:8825338. like 5-ct, 5-ht (3-300 microm) could evoke an lsd-sensitive response in the presence of the 5-ht2 receptor antagonist, ketanserin and the 5-ht3 receptor antagonist, tropisetron (all 1 microm). 1996-11-22 2023-08-12 rat
P P Grandaw, R E Purd. Serotonin-induced vasoconstriction in rabbit femoral artery: mediation by both 5-HT2 serotonergic and alpha 1-adrenoceptors. Journal of cardiovascular pharmacology. vol 27. issue 6. 1996-11-21. PMID:8761853. in contrast, the reversible, competitive 5-ht2 antagonist ketanserin shifted the first phase of the serotonin crc to the right ina concentration-dependent manner but had little or no effect on the second phase. 1996-11-21 2023-08-12 rabbit
P P Grandaw, R E Purd. Serotonin-induced vasoconstriction in rabbit femoral artery: mediation by both 5-HT2 serotonergic and alpha 1-adrenoceptors. Journal of cardiovascular pharmacology. vol 27. issue 6. 1996-11-21. PMID:8761853. we conclude that the first phase of the serotonin crc in rabbit femoral artery was mediated predominantly by 5-ht2 receptors and that the second phase was mediated by alpha 1-adrenoceptors. 1996-11-21 2023-08-12 rabbit
J Akiyoshi, K Isogawa, K Yamada, H Nagayama, I Fuji. Effects of antidepressants on intracellular Ca2+ mobilization in CHO cells transfected with the human 5-HT2C receptors. Biological psychiatry. vol 39. issue 12. 1996-11-18. PMID:8780834. exposure to 5-ht, a 5-ht receptor agonist, mcpp [1-(3-chlorophenyl)piperazine dihydrochloride], a 5-ht2c agonist, and doi [1-(4-iodo-2,5-dimethoxyphenyl)-2-aminopropane], a 5-ht2c and 5-ht2 agonist, resulted in increased intracellular ca2+ levels. 1996-11-18 2023-08-12 human
H U Bryant, D L Nelson, D Button, H W Cole, M B Baez, V L Lucaites, D B Wainscott, C Whitesitt, J Reel, R Simon, G A Koppe. A novel class of 5-HT2A receptor antagonists: aryl aminoguanidines. Life sciences. vol 59. issue 15. 1996-11-18. PMID:8845011. local delivery of serotonin (5-ht) produces a rapid edematous response in soft tissues via increased fluid extravasation which is prevented by 5-ht2 antagonists such as ketanserin or mianserin. 1996-11-18 2023-08-12 human
N J Hrib, J G Jurcak, D E Bregna, K L Burgher, H B Hartman, S Kafka, L L Kerman, S Kongsamut, J E Roehr, M R Szewczak, A T Woods-Kettelberger, R Corbet. Structure-activity relationships of a series of novel (piperazinylbutyl)thiazolidinone antipsychotic agents related to 3-[4-[4-(6-fluorobenzo[b]thien-3-yl)-1-piperazinyl]butyl]-2,5,5- trimethyl-4-thiazolidinone maleate. Journal of medicinal chemistry. vol 39. issue 20. 1996-11-14. PMID:8831770. a series of piperazinyl butyl thiazolidinones structurally related to this compound were prepared and evaluated in vitro for dopamine d2 and serotonin 5ht2 and 5ht1a receptor affinity. 1996-11-14 2023-08-12 Not clear
T Hori, T Suzuki, A Baba, S Abe, T Yamamoto, T Moroji, H Shiraish. Effects of phencyclidine metabolites on serotonin uptake in rat brain. Neuroscience letters. vol 209. issue 3. 1996-11-08. PMID:8736633. pcp and its metabolites inhibited the uptake of [3h]5-ht and the binding of [3h]paroxetine in rat brain, while they failed to inhibit either [3h]5-ht binding to 5-ht1 receptors or [3h]ketanserin binding to 5-ht2 receptors. 1996-11-08 2023-08-12 rat
M J Owens, C A Ballenger, D L Knight, C B Nemerof. Platelet 5-hydroxytryptamine (5-HT) transporter and 5-HT2A receptor binding after chronic hypercorticosteronemia, (+/-)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane administration or neurotoxin-induced depletion of central nervous system 5-HT in the rat. The Journal of pharmacology and experimental therapeutics. vol 278. issue 3. 1996-11-05. PMID:8819484. there is considerable evidence that the number of platelet 5-hydroxytryptamine (5-ht) transporter binding sites, as measured by [3h]imipramine binding, are significantly decreased, and platelet 5-ht2 receptor density is increased, in drug-free patients with major depression. 1996-11-05 2023-08-12 rat
M J Owens, C A Ballenger, D L Knight, C B Nemerof. Platelet 5-hydroxytryptamine (5-HT) transporter and 5-HT2A receptor binding after chronic hypercorticosteronemia, (+/-)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane administration or neurotoxin-induced depletion of central nervous system 5-HT in the rat. The Journal of pharmacology and experimental therapeutics. vol 278. issue 3. 1996-11-05. PMID:8819484. to investigate whether these changes in the platelet 5-ht transporter or 5-ht2 receptor sites resulted from known or hypothesized biochemical changes observed in major depression, we examined, in the rat, whether a chronic hyperglucocorticoid state, or decreases or increases in central nervous system 5-ht neurotransmission, altered binding of the selective ligands [3h]citalopram and [125i] (+/-)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane to platelet and brain 5-ht transporters and 5-ht2 receptors, respectively. 1996-11-05 2023-08-12 rat
G J Marek, G K Aghajania. LSD and the phenethylamine hallucinogen DOI are potent partial agonists at 5-HT2A receptors on interneurons in rat piriform cortex. The Journal of pharmacology and experimental therapeutics. vol 278. issue 3. 1996-11-05. PMID:8819525. correlations between 5-hydroxytryptamine (5-ht) receptor binding affinities and human hallucinogenic potency have suggested that 5-ht2 receptors mediate the hallucinogenic effects of lysergic acid diethylamide (lsd) and phenethylamine hallucinogens. 1996-11-05 2023-08-12 human
K Andersen, T Liljefors, J Hyttel, J Perregaar. Serotonin 5-HT2 receptor, dopamine D2 receptor, and alpha 1 adrenoceptor antagonists. Conformationally flexible analogues of the atypical antipsychotic sertindole. Journal of medicinal chemistry. vol 39. issue 19. 1996-11-04. PMID:8809161. serotonin 5-ht2 receptor, dopamine d2 receptor, and alpha 1 adrenoceptor antagonists. 1996-11-04 2023-08-12 Not clear
J Strosznajder, M Chalimoniuk, M Samochock. Activation of serotonergic 5-HT1A receptor reduces Ca(2+)- and glutamatergic receptor-evoked arachidonic acid and No/cGMP release in adult hippocampus. Neurochemistry international. vol 28. issue 4. 1996-10-29. PMID:8740452. an antagonist of serotonergic 5-ht2 receptor, ketanserin, has no effect on the ca2+ and serotonin action. 1996-10-29 2023-08-12 rat
J C Shih, K Chen, T K Gallahe. Structure and function of serotonin 5-HT2 receptors. NIDA research monograph. vol 146. 1996-10-25. PMID:8742804. structure and function of serotonin 5-ht2 receptors. 1996-10-25 2023-08-12 Not clear
V D Petkov, S Belcheva, E Konstantinova, R Kehayo. Participation of different 5-HT receptors in the memory process in rats and its modulation by the serotonin depletor p-chlorophenylalanine. Acta neurobiologiae experimentalis. vol 55. issue 4. 1996-10-24. PMID:8713354. the results obtained show different participation of 5-ht1a, 5-ht2 and 5-ht3 receptors in the mechanisms of the memory process; the nature of this involvement is modulated by the brain level of serotonin. 1996-10-24 2023-08-12 rat
H S Sharma, J Westman, J C Navarro, P K Dey, F Nyber. Probable involvement of serotonin in the increased permeability of the blood-brain barrier by forced swimming. An experimental study using Evans blue and 131I-sodium tracers in the rat. Behavioural brain research. vol 72. issue 1-2. 1996-10-24. PMID:8788871. these observations suggest that (i) 5-ht plays an important role in the breakdown of bbb permeability in fs, (ii) this effect of 5-ht on bbb permeability is mediated by 5-ht2 receptors, and (iii) fs induced increase in bbb permeability is age dependent. 1996-10-24 2023-08-12 rat
H Inoue, N Nagata, Y Koshihar. Participation of serotonin in capsaicin-induced mouse ear edema. Japanese journal of pharmacology. vol 69. issue 1. 1996-10-24. PMID:8847833. 5-ht2 antagonists markedly suppressed the edema response to 5-ht and its receptor agonists, whereas any antagonist for 5-ht1, 5-ht3 and 5-ht4-receptors had no effect. 1996-10-24 2023-08-12 mouse