All Relations between 5-ht receptor 2 and serotonin

Publication Sentence Publish Date Extraction Date Species
P M Sweetnam, J Lancaster, A Snowman, J L Collins, S Perschke, C Bauer, J Ferkan. Receptor binding profile suggests multiple mechanisms of action are responsible for ibogaine's putative anti-addictive activity. Psychopharmacology. vol 118. issue 4. 1995-10-23. PMID:7568622. these included the mu, delta, kappa, opiate, 5ht2, 5ht3, and muscarinic1 and 2 receptors, and the dopamine, norepinephrine, and serotonin uptake sites. 1995-10-23 2023-08-12 Not clear
V J Watts, C P Lawler, D R Fox, K A Neve, D E Nichols, R B Mailma. LSD and structural analogs: pharmacological evaluation at D1 dopamine receptors. Psychopharmacology. vol 118. issue 4. 1995-10-23. PMID:7568626. several of these compounds have been reported previously to bind with high affinity to serotonin 5ht2 (i.e., 3h-ketanserin) sites in the rat frontal cortex (k0.5 5-30 nm). 1995-10-23 2023-08-12 rat
R Gebhard, K Zilles, A Schleicher, B J Everitt, T W Robbins, I Diva. Parcellation of the frontal cortex of the New World monkey Callithrix jacchus by eight neurotransmitter-binding sites. Anatomy and embryology. vol 191. issue 6. 1995-10-19. PMID:7677258. the respective distributions of eight different receptors for the transmitters l-glutamate (l-glu and nmda), gamma-amino-butyric acid (gabaa), noradrenaline (alpha 1), acetylcholine (m1 and m2) and serotonin (5-ht1 and 5-ht2) were therefore studied in cortical areas of the frontal lobe of the lissencephalic new world monkey, callithrix jacchus. 1995-10-19 2023-08-12 monkey
P J Brent, G T Pan. Sigma binding site ligands inhibit cell proliferation in mammary and colon carcinoma cell lines and melanoma cells in culture. European journal of pharmacology. vol 278. issue 2. 1995-10-18. PMID:7671999. the effect of sigma ligands in mcf-7 and melanoma cells was not due to blockade of dopamine d1 and d2 receptors, serotonin (5-ht2) receptors, n-methyl-d-aspartate (nmda)/phencyclidine receptors, beta-adrenoceptors or opioid receptors, since 100 microm sch 23390, raclopride, mianserin, (+)-mk-801, propranolol and 1 microm naloxone respectively, were ineffective. 1995-10-18 2023-08-12 human
B Sadzot, C Lemaire, P Maquet, E Salmon, A Plenevaux, C Degueldre, J P Hermanne, M Guillaume, R Cantineau, D Coma. Serotonin 5HT2 receptor imaging in the human brain using positron emission tomography and a new radioligand, [18F]altanserin: results in young normal controls. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 15. issue 5. 1995-10-18. PMID:7673371. serotonin 5ht2 receptor imaging in the human brain using positron emission tomography and a new radioligand, [18f]altanserin: results in young normal controls. 1995-10-18 2023-08-12 human
Y Hattori, H Kawasaki, M Kanno, M Fuka. Enhanced 5-HT2 receptor mediated contractions in diabetic rat aorta: participation of Ca2+ channels associated with protein kinase C activity. Journal of vascular research. vol 32. issue 4. 1995-10-05. PMID:7654879. in the presence of extracellular ca2+ (2.5 mm), the contractile responses to stimulation of 5-ht2 receptors with 5-ht were greater in aortas from diabetic rats as compared with those from age-matched controls. 1995-10-05 2023-08-12 rat
E Hong, C Castillo, E Flores, F Mercede. [Serotoninergic receptors and cardiovascular diseases]. Gaceta medica de Mexico. vol 130. issue 3. 1995-10-05. PMID:7657075. 5-ht may lower the arterial blood pressure by an action on central 5-ht1a receptors, or may increase it by stimulation of 5-ht2 receptors located in vascular smooth muscle. 1995-10-05 2023-08-12 Not clear
J Mendels, F Reimherr, R N Marcus, D L Roberts, R J Francis, S F Anto. A double-blind, placebo-controlled trial of two dose ranges of nefazodone in the treatment of depressed outpatients. The Journal of clinical psychiatry. vol 56 Suppl 6. 1995-09-28. PMID:7649971. nefazodone hydrochloride, a 5-ht2 receptor antagonist that selectively inhibits serotonin reuptake, was evaluated in a double-blind, dose-finding study of novel design, involving 240 patients with major depression. 1995-09-28 2023-08-12 Not clear
J Fawcett, R N Marcus, S F Anton, K O'Brien, U Schwidersk. Response of anxiety and agitation symptoms during nefazodone treatment of major depression. The Journal of clinical psychiatry. vol 56 Suppl 6. 1995-09-28. PMID:7649972. nefazodone blocks serotonin2 (5-ht2) receptors and selectively inhibits serotonin (5-ht) reuptake. 1995-09-28 2023-08-12 Not clear
K Rickels, D S Robinson, E Schweizer, R N Marcus, D L Robert. Nefazodone: aspects of efficacy. The Journal of clinical psychiatry. vol 56 Suppl 6. 1995-09-28. PMID:7649973. nefazodone hydrochloride, a 5-ht2 receptor antagonist and serotonin (5-ht) uptake inhibitor, was evaluated in four phase 3 double-blind, imipramine- and placebo-controlled studies involving outpatients with major depression. 1995-09-28 2023-08-12 Not clear
J G Pires, S R Silva, H A Futuro-Net. 5-HT2 receptor blockade by ICI 170,809 does not affect the inhibitory effect of the 5-HT1A receptor ligand gepirone on neuroleptic-induced catalepsy. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 27. issue 10. 1995-09-21. PMID:7640635. however, the role of 5-ht2 receptors in the modulation of nic is still controversial and there is evidence from behavioral models other than nic suggesting the existence of functional interaction between the two subtypes of 5-ht receptors. 1995-09-21 2023-08-12 rat
J C Langer, S M Liebman, P K Monk, G J Pelletie. Mast cell mediators and peritoneal adhesion formation in the rat. The Journal of surgical research. vol 59. issue 3. 1995-09-15. PMID:7643592. these data suggest that mast cells mediate peritoneal adhesion formation in the rat through release of serotonin acting on 5ht2 receptors. 1995-09-15 2023-08-12 rat
H G Baumgarten, Z Grozdanovi. [The role of serotonin in behavior modulation]. Fortschritte der Neurologie-Psychiatrie. vol 63 Suppl 1. 1995-09-14. PMID:7635393. these effects of serotonin are mediated by multiple receptor subtypes with distinct pre- and postsynaptic localisation and regional distribution pattern, acting via amplifying (5-ht2 receptors) or desamplifying (5-ht1 receptors) g-protein-dependent transduction mechanisms. 1995-09-14 2023-08-12 Not clear
K B Thor, M A Katofias. Effects of duloxetine, a combined serotonin and norepinephrine reuptake inhibitor, on central neural control of lower urinary tract function in the chloralose-anesthetized female cat. The Journal of pharmacology and experimental therapeutics. vol 274. issue 2. 1995-09-08. PMID:7636716. the effects of duloxetine on bladder capacity were antagonized by methiothepin, a non-selective 5ht receptor antagonist, but not by the other 5ht and ne receptor antagonists examined: ly53857, a 5ht2 antagonist; prazosin, an alpha-1-adrenergic receptor antagonist; idazoxan, an alpha-2-adrenergic receptor antagonist; or propranolol, a beta-adrenergic receptor antagonist. 1995-09-08 2023-08-12 cat
K B Thor, M A Katofias. Effects of duloxetine, a combined serotonin and norepinephrine reuptake inhibitor, on central neural control of lower urinary tract function in the chloralose-anesthetized female cat. The Journal of pharmacology and experimental therapeutics. vol 274. issue 2. 1995-09-08. PMID:7636716. however, under conditions of bladder irritation, duloxetine suppresses bladder activity through 5ht receptor mechanisms and enhances external urethral sphincter activity through 5ht2 and alpha-1-adrenergic mechanisms. 1995-09-08 2023-08-12 cat
A Montero, A Rodríguez-López, M Reverte, J M López-Novo. The effect of LU-49938 (nexopamil) on the activation by serotonin of mesangial cells. Fundamental & clinical pharmacology. vol 9. issue 2. 1995-09-07. PMID:7628831. the main purpose of this study is to analyze whether nexopamil, a verapamil derivative, with the property of blocking simultaneously calcium channels and 5-ht2 receptors, could modify the contractile and mitogenic effects of serotonin on cultured rat mesangial cells. 1995-09-07 2023-08-12 rat
A Montero, A Rodríguez-López, M Reverte, J M López-Novo. The effect of LU-49938 (nexopamil) on the activation by serotonin of mesangial cells. Fundamental & clinical pharmacology. vol 9. issue 2. 1995-09-07. PMID:7628831. the effects of 5-ht on thymidine uptake and cell proliferation were blocked by the selective 5-ht2 receptor blocker ketanserin 10(-5) m. nexopamil abolished in a concentration-dependent way the serotonin-induced [3h]thymidine incorporation into dna, and the serotonin-induced increase in number of cells. 1995-09-07 2023-08-12 rat
P Kienbaum, M Braun, T Hohlfeld, A A Weber, M Sarbia, K Schrö. Antiatherosclerotic effects of oral naftidrofuryl in cholesterol-fed rabbits involve inhibition of neutrophil function. Journal of cardiovascular pharmacology. vol 25. issue 5. 1995-09-05. PMID:7543172. we investigated the action of oral naftidrofuryl, a serotonin (5-ht2)antagonist, on atheromatous plaque formation, endothelial function, and neutrophil activity in cholesterol-fed (1% for 12 weeks) rabbits. 1995-09-05 2023-08-12 Not clear
N Bonhomme, P De Deurwaèrdere, M Le Moal, U Spampinat. Evidence for 5-HT4 receptor subtype involvement in the enhancement of striatal dopamine release induced by serotonin: a microdialysis study in the halothane-anesthetized rat. Neuropharmacology. vol 34. issue 3. 1995-09-01. PMID:7543190. these results demonstrate that in vivo 5-ht exerts a facilitatory influence on striatal da release and that the 5-ht4, but not the 5-ht1, 5-ht2 or 5-ht3, receptor subtype is implicated, at least partially, in this effect. 1995-09-01 2023-08-12 rat
b' M Yoneda, Y Tach\\xc3\\xa. Serotonin enhances gastric acid response to TRH analogue in dorsal vagal complex through 5-HT2 receptors in rats. The American journal of physiology. vol 269. issue 1 Pt 2. 1995-09-01. PMID:7631881.' serotonin enhances gastric acid response to trh analogue in dorsal vagal complex through 5-ht2 receptors in rats. 1995-09-01 2023-08-12 rat