| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| b' M Yoneda, Y Tach\\xc3\\xa. Serotonin enhances gastric acid response to TRH analogue in dorsal vagal complex through 5-HT2 receptors in rats. The American journal of physiology. vol 269. issue 1 Pt 2. 1995-09-01. PMID:7631881.' |
the 5-ht2 receptor antagonist, 3-[2-(4-fluorobenzoyl)-1-piperdinyl]ethyl]-2,4(1h,3h)-quinazoli nedone tartrate (ketanserin; 20 nmol), injected intracisternally abolished the potentiating action of 5-ht injected into the dvc with rx-77368, whereas the 5-ht antagonists 8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4,5]- decan-4-one (spiperone; 5-ht2/1a) and 1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl-1h-imidazol-1- yl)methyl]-4h-carbazol-4-one hydrochloride dihydrate (ondansetron; 5-ht3) did not. |
1995-09-01 |
2023-08-12 |
rat |
| b' M Yoneda, Y Tach\\xc3\\xa. Serotonin enhances gastric acid response to TRH analogue in dorsal vagal complex through 5-HT2 receptors in rats. The American journal of physiology. vol 269. issue 1 Pt 2. 1995-09-01. PMID:7631881.' |
these data suggest that 5-ht acting at 5-ht2 receptors in the dvc potentiates the gastric acid response to exogenous and endogenous trh. |
1995-09-01 |
2023-08-12 |
rat |
| V A Curtis, P Wright, A Reveley, R Kerwin, J V Luce. Effect of clozapine on d-fenfluramine-evoked neuroendocrine responses in schizophrenia and its relationship to clinical improvement. The British journal of psychiatry : the journal of mental science. vol 166. issue 5. 1995-08-31. PMID:7620750. |
clozapine is an effective antipsychotic that has high affinity for serotonin type 2 (5-ht2) receptors. |
1995-08-31 |
2023-08-12 |
Not clear |
| G Sedvall, S Pauli, L Farde, P Karlsson, S Nyberg, A L Nordströ. Recent developments in PET scan imaging of neuroreceptors in schizophrenia. The Israel journal of psychiatry and related sciences. vol 32. issue 1. 1995-08-31. PMID:7622344. |
by using a combination of selective ligands labeled with positron emitting isotopes d1- and d2 dopamine, serotonin 5ht2, and benzodiazepine receptors were examined in schizophrenic patients (dsm-iii-r) and healthy control subjects. |
1995-08-31 |
2023-08-12 |
human |
| D J Nutt, S J Wilson, N J Couplan. Use of selective serotonin reuptake inhibitors and other serotonergic drugs in the biological dissection of affective disorders. International clinical psychopharmacology. vol 9 Suppl 4. 1995-08-31. PMID:7622825. |
peripheral markers include platelet serotonin concentrations, the density and affinity of platelet serotonin reuptake and platelet 5-ht2 receptors, and plasma serotonin concentrations. |
1995-08-31 |
2023-08-12 |
Not clear |
| H He, J S Richardso. A pharmacological, pharmacokinetic and clinical overview of risperidone, a new antipsychotic that blocks serotonin 5-HT2 and dopamine D2 receptors. International clinical psychopharmacology. vol 10. issue 1. 1995-08-30. PMID:7542676. |
a pharmacological, pharmacokinetic and clinical overview of risperidone, a new antipsychotic that blocks serotonin 5-ht2 and dopamine d2 receptors. |
1995-08-30 |
2023-08-12 |
human |
| H He, J S Richardso. A pharmacological, pharmacokinetic and clinical overview of risperidone, a new antipsychotic that blocks serotonin 5-HT2 and dopamine D2 receptors. International clinical psychopharmacology. vol 10. issue 1. 1995-08-30. PMID:7542676. |
its neuropharmacological properties, characterized by potent central antagonism of both serotonin 5-ht2 and dopamine d2 receptors, also differ from those of most other antipsychotic drugs. |
1995-08-30 |
2023-08-12 |
human |
| H He, J S Richardso. A pharmacological, pharmacokinetic and clinical overview of risperidone, a new antipsychotic that blocks serotonin 5-HT2 and dopamine D2 receptors. International clinical psychopharmacology. vol 10. issue 1. 1995-08-30. PMID:7542676. |
the clinical success of risperidone suggests that the development of compounds with selective affinity for 5-ht2 or other serotonin receptors may result in even further improvements in the pharmacotherapy of psychiatric disorders. |
1995-08-30 |
2023-08-12 |
human |
| M Wikström, R Hill, J Hellgren, S Grillne. The action of 5-HT on calcium-dependent potassium channels and on the spinal locomotor network in lamprey is mediated by 5-HT1A-like receptors. Brain research. vol 678. issue 1-2. 1995-08-30. PMID:7620887. |
the 5-ht1a receptor agonist 8-oh-dpat ((+/-)-8-hydroxy-dipropylaminotetralin hydrobromide), the 5-ht1 receptor agonist 5-ct (5-carboxyamidotryptamine maleate) and the 5-ht2 receptor agonist alpha-ch3-5-ht (alpha-methylserotonin maleate) all reproduced the actions of 5-ht at both the cellular and the network levels. |
1995-08-30 |
2023-08-12 |
Not clear |
| Y G Papakostas, M Markianos, G N Papadimitriou, I M Zervas, C N Stefani. Effects of methysergide and ritanserin on the prolactin and thyrotropin responses to TRH in depressed patients. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 5. issue 1. 1995-08-24. PMID:7613098. |
we studied the effect of the serotonin antagonists methysergide (non-selective 5-ht1/5-ht2 blocker with dopaminergic properties) and ritanserin (selective 5-ht2 blocker) on the tsh and prl responses to trh stimulation in two groups of medication-free female depressed patients in a double-blind, within-subject design. |
1995-08-24 |
2023-08-12 |
Not clear |
| T Tadano, M Neda, M Hozumi, A Yonezawa, Y Arai, T Fujita, H Kinemuchi, K Kisar. alpha-Methylated tryptamine derivatives induce a 5-HT receptor-mediated head-twitch response in mice. Neuropharmacology. vol 34. issue 2. 1995-08-23. PMID:7617148. |
this probably results in release of 5-ht with a concomitant increased interaction with postsynaptic 5-ht2 receptors. |
1995-08-23 |
2023-08-12 |
mouse |
| R Blumensohn, G Ratzoni, A Weizman, M Israeli, N Greuner, A Apter, S Tyano, A Biego. Reduction in serotonin 5HT2 receptor binding on platelets of delinquent adolescents. Psychopharmacology. vol 118. issue 3. 1995-08-23. PMID:7617829. |
reduction in serotonin 5ht2 receptor binding on platelets of delinquent adolescents. |
1995-08-23 |
2023-08-12 |
human |
| R Blumensohn, G Ratzoni, A Weizman, M Israeli, N Greuner, A Apter, S Tyano, A Biego. Reduction in serotonin 5HT2 receptor binding on platelets of delinquent adolescents. Psychopharmacology. vol 118. issue 3. 1995-08-23. PMID:7617829. |
the possible involvement of serotonin receptors of the 5ht2 type in aggressive behavior was studied in juvenile delinquents. |
1995-08-23 |
2023-08-12 |
human |
| R Blumensohn, G Ratzoni, A Weizman, M Israeli, N Greuner, A Apter, S Tyano, A Biego. Reduction in serotonin 5HT2 receptor binding on platelets of delinquent adolescents. Psychopharmacology. vol 118. issue 3. 1995-08-23. PMID:7617829. |
these results support a role for serotonin in general and 5ht2 receptors in particular in human aggressive behavior. |
1995-08-23 |
2023-08-12 |
human |
| R Ciccocioppo, I Panocka, E Stefanini, G L Gessa, M Mass. Low responsiveness to agents evoking 5-HT2 receptor-mediated behaviors in Sardinian alcohol-preferring rats. Pharmacology, biochemistry, and behavior. vol 51. issue 1. 1995-08-22. PMID:7542392. |
the selective nk3 tachykinin agonist senktide evokes in rodents 5-ht mediated behaviors, including 5-ht2 receptor-mediated wet dog shakes (wds) and head shakes (hs). |
1995-08-22 |
2023-08-12 |
rat |
| R Ciccocioppo, I Panocka, E Stefanini, G L Gessa, M Mass. Low responsiveness to agents evoking 5-HT2 receptor-mediated behaviors in Sardinian alcohol-preferring rats. Pharmacology, biochemistry, and behavior. vol 51. issue 1. 1995-08-22. PMID:7542392. |
hs induced by the icv injection of 5-ht agonists endowed with marked activity at 5-ht2 receptors, such as quipazine (1500-6000 ng/rat) or doi (500-3500 ng/rat), were much less pronounced in sp rats than in nsw rats. |
1995-08-22 |
2023-08-12 |
rat |
| N Wiernsperge. Serotonin 5-HT2 receptors and brain circulation. Journal of cardiovascular pharmacology. vol 16 Suppl 3. 1995-08-17. PMID:1369712. |
serotonin 5-ht2 receptors and brain circulation. |
1995-08-17 |
2023-08-11 |
Not clear |
| N Wiernsperge. Serotonin 5-HT2 receptors and brain circulation. Journal of cardiovascular pharmacology. vol 16 Suppl 3. 1995-08-17. PMID:1369712. |
5-ht2 receptors appear to be the major effector of these actions of serotonin, judging from experimental and clinical pharmacology data with specific or partial 5-ht2 serotonergic antagonists. |
1995-08-17 |
2023-08-11 |
Not clear |
| N K Hollenberg, Q Ni. The effect of naftidrofuryl, a 5-HT2 antagonist, on collateral vascular responses to serotonin and to platelet activation. Journal of cardiovascular pharmacology. vol 16 Suppl 3. 1995-08-17. PMID:1369716. |
the effect of naftidrofuryl, a 5-ht2 antagonist, on collateral vascular responses to serotonin and to platelet activation. |
1995-08-17 |
2023-08-11 |
Not clear |
| N K Hollenberg, Q Ni. The effect of naftidrofuryl, a 5-HT2 antagonist, on collateral vascular responses to serotonin and to platelet activation. Journal of cardiovascular pharmacology. vol 16 Suppl 3. 1995-08-17. PMID:1369716. |
collateral arterial supersensitivity to serotonin has been attributed to a 5-ht2 receptor mechanism because of the effectiveness of ketanserin in reversing that vasoconstrictor response. |
1995-08-17 |
2023-08-11 |
Not clear |