All Relations between 5-ht receptor 2 and serotonin

Publication Sentence Publish Date Extraction Date Species
P Piguet, M Galva. Transient and long-lasting actions of 5-HT on rat dentate gyrus neurones in vitro. The Journal of physiology. vol 481 ( Pt 3). 1995-05-08. PMID:7707231. in some cells, a longer lasting increase in spontaneous ipsp frequency was observed during application of 5-ht; this effect was blocked by the 5-ht2 receptor antagonist mdl 100,907. 1995-05-08 2023-08-12 human
P Piguet, M Galva. Transient and long-lasting actions of 5-HT on rat dentate gyrus neurones in vitro. The Journal of physiology. vol 481 ( Pt 3). 1995-05-08. PMID:7707231. it is concluded that 5-ht hyperpolarizes granule cells via postsynaptic 5-ht1a receptors and increases spontaneous gaba release from inhibitory interneurones via the activation of 5-ht3 receptors and/or 5-ht2 receptors. 1995-05-08 2023-08-12 human
J Sawynok, A Rei. Spinal supersensitivity to 5-HT1, 5-HT2 and 5-HT3 receptor agonists following 5,7-dihydroxytryptamine. European journal of pharmacology. vol 264. issue 3. 1995-04-28. PMID:7698162. the present study examined functional supersensitivity to 5-hydroxytryptamine (5-ht) and 5-ht ligands selective for 5-ht1, 5-ht2 and 5-ht3 receptors in two tests for nociception following the spinal administration of 5,7-dihydroxytryptamine (5,7-dht). 1995-04-28 2023-08-12 Not clear
J Sawynok, A Rei. Spinal supersensitivity to 5-HT1, 5-HT2 and 5-HT3 receptor agonists following 5,7-dihydroxytryptamine. European journal of pharmacology. vol 264. issue 3. 1995-04-28. PMID:7698162. these results indicate that supersensitivity occurs with 5-ht and 5-ht1 receptor ligands but not with 5-ht2 or 5-ht3 receptor ligands. 1995-04-28 2023-08-12 Not clear
G A Gudelsky, B K Yamamoto, J F Nas. Potentiation of 3,4-methylenedioxymethamphetamine-induced dopamine release and serotonin neurotoxicity by 5-HT2 receptor agonists. European journal of pharmacology. vol 264. issue 3. 1995-04-28. PMID:7698172. potentiation of 3,4-methylenedioxymethamphetamine-induced dopamine release and serotonin neurotoxicity by 5-ht2 receptor agonists. 1995-04-28 2023-08-12 rat
G A Gudelsky, B K Yamamoto, J F Nas. Potentiation of 3,4-methylenedioxymethamphetamine-induced dopamine release and serotonin neurotoxicity by 5-HT2 receptor agonists. European journal of pharmacology. vol 264. issue 3. 1995-04-28. PMID:7698172. the effects of the 5-ht2 receptor agonists 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (doi) and 5-methoxy-n,n-dimethyltryptamine (5-meodmt) on 3,4-methylenedioxymethamphetamine (mdma)-induced dopamine release and 5-ht depletion in the striatum were studied. 1995-04-28 2023-08-12 rat
G A Gudelsky, B K Yamamoto, J F Nas. Potentiation of 3,4-methylenedioxymethamphetamine-induced dopamine release and serotonin neurotoxicity by 5-HT2 receptor agonists. European journal of pharmacology. vol 264. issue 3. 1995-04-28. PMID:7698172. it is concluded that activation of 5-ht2 receptors is an important determinant of the acute increase in extracellular dopamine and, consequently, the long-term depletion of brain 5-ht produced by mdma. 1995-04-28 2023-08-12 rat
R Perrone, F Berardi, N A Colabufo, M Leopoldo, V Tortorella, F Fiorentini, V Olgiati, A Ghiglieri, S Govon. High affinity and selectivity on 5-HT1A receptor of 1-aryl-4-[1-tetralin)alkyl]piperazines. 2. Journal of medicinal chemistry. vol 38. issue 6. 1995-04-28. PMID:7699710. final compounds were evaluated for in vitro activity on dopamine d-1 and d-2, serotonin 5-ht1a, 5-ht1b, 5-ht1c, and 5-ht2, alpha 1 adrenergic, and sigma receptors by radioreceptor binding assay. 1995-04-28 2023-08-12 Not clear
O A Nedergaard, J Mølle. Inhibition by (-)-deprenyl of agonist-evoked contractions in rabbit aorta. Pharmacology & toxicology. vol 75. issue 6. 1995-04-27. PMID:7899260. it is concluded that (-)-deprenyl is a weak inhibitor of postjunctional alpha 1-adrenoceptors, 5-hydroxytryptamine (5-ht2) receptors, and histamine (h1) receptors. 1995-04-27 2023-08-12 rabbit
M Toth, D Ding, T Shen. The 5' flanking region of the serotonin 2 receptor gene directs brain specific expression in transgenic animals. Brain research. Molecular brain research. vol 27. issue 2. 1995-04-25. PMID:7898316. the neuron is the predominant cell type expressing the serotonin 2 (5-ht2) receptor in the central nervous system. 1995-04-25 2023-08-12 mouse
A Erfurth, A M Gardier, E Ribeiro, R J Wurtma. Effects of subchronic pretreatment with D-fenfluramine or p-chloroamphetamine on [3H]inositolmonophosphate accumulation in rat cortical miniprisms. Brain research. vol 665. issue 1. 1995-04-12. PMID:7882002. phosphatidylinositol (pi) breakdown in rat cerebral cortex is stimulated by serotonin (5-ht), acting via 5-ht2 and possibly 5-ht3 receptors and by acetylcholine or carbachol, acting via muscarinic m1 and m3 receptors. 1995-04-12 2023-08-12 rat
H Xie, C R Triggl. The endothelium contributes to the contractile responses of the human umbilical artery to 5-hydroxytryptamine and endothelin-1 under low but not high PO2 conditions. Canadian journal of physiology and pharmacology. vol 72. issue 10. 1995-04-12. PMID:7882182. (v) the 5-ht2 receptor antagonist ketanserin at low concentration (10 nm) inhibited contractile responses to 5-ht in an apparently competitive manner. 1995-04-12 2023-08-12 human
R W Rhoades, C A Bennett-Clarke, M Y Shi, R D Moone. Effects of 5-HT on thalamocortical synaptic transmission in the developing rat. Journal of neurophysiology. vol 72. issue 5. 1995-04-12. PMID:7884470. the 5-ht1a agonist [(+/-)8-hydroxydipropylaminotetralin hbr] (8-oh-dpat) had less effect on the vpm-elicited epsp, and the effects of 5-ht upon this response were generally not antagonized by either 1-(2-methoxyphenyl)-4-[4-(2- phthalimmido)butyl]piperazine hbr (a 5-ht1a antagonist) or ketanserine (a 5-ht2 antagonist) or spiperone (a 5-ht1a and 2 antagonist). 1995-04-12 2023-08-12 rat
E S Ellis, C Byrne, O E Murphy, N S Tilford, G S Baxte. Mediation by 5-hydroxytryptamine2B receptors of endothelium-dependent relaxation in rat jugular vein. British journal of pharmacology. vol 114. issue 2. 1995-04-10. PMID:7881740. in experiments conducted in the presence of ketanserin to preclude involvement of 5-ht2 receptors, the mixed 5-ht2b/2c antagonist, sb 200646, acted as an antagonist of 5-ht at the endothelial 5-ht receptor (pa2 = 7.2). 1995-04-10 2023-08-12 rat
D Keega. Risperidone: neurochemical, pharmacologic and clinical properties of a new antipsychotic drug. Canadian journal of psychiatry. Revue canadienne de psychiatrie. vol 39. issue 9 Suppl 2. 1995-04-06. PMID:7533051. risperidone, a novel antipsychotic with high binding affinity for serotonin 5-ht2 and a lesser affinity for dopamine d2 receptors, is described and clinical studies are reviewed. 1995-04-06 2023-08-12 Not clear
A Walcourt-Ambakederemo, W Winlo. 5-HT receptors on identified Lymnaea neurones in culture: pharmacological characterization of 5-HT2 receptors. General pharmacology. vol 25. issue 6. 1995-04-06. PMID:7875529. 5-ht receptors on identified lymnaea neurones in culture: pharmacological characterization of 5-ht2 receptors. 1995-04-06 2023-08-12 Not clear
A Walcourt-Ambakederemo, W Winlo. 5-HT receptors on identified Lymnaea neurones in culture: pharmacological characterization of 5-HT2 receptors. General pharmacology. vol 25. issue 6. 1995-04-06. PMID:7875529. the vertebrate 5-ht2 receptor agonist alpha-methylserotonin maleate (10(-4) m), inhibited most of the neurones inhibited by 5-ht (10(-3) m). 1995-04-06 2023-08-12 Not clear
A Walcourt-Ambakederemo, W Winlo. 5-HT receptors on identified Lymnaea neurones in culture: pharmacological characterization of 5-HT2 receptors. General pharmacology. vol 25. issue 6. 1995-04-06. PMID:7875529. in cells where 5-ht failed to evoke any effects, the 5-ht2 agonist also lacked an effect. 1995-04-06 2023-08-12 Not clear
A Walcourt-Ambakederemo, W Winlo. 5-HT receptors on identified Lymnaea neurones in culture: pharmacological characterization of 5-HT2 receptors. General pharmacology. vol 25. issue 6. 1995-04-06. PMID:7875529. bath application of the 5-ht2 receptor antagonists ketanserin and methysergide (10(-4) m), not only blocked spike generation, but also reduced both the excitatory and inhibitory responses to both 5-ht and alpha-methylserotonin maleate, while the 5-ht3 antagonist mdl 72222 (10(-4) m) failed to block alpha-methylserotonin maleate effects. 1995-04-06 2023-08-12 Not clear
A Walcourt-Ambakederemo, W Winlo. 5-HT receptors on identified Lymnaea neurones in culture: pharmacological characterization of 5-HT2 receptors. General pharmacology. vol 25. issue 6. 1995-04-06. PMID:7875529. the above results suggest that 5-ht2 receptors are involved in the responses of the cgcs and the buccal motorneurones to 5-ht in lymnaea stagnalis. 1995-04-06 2023-08-12 Not clear