All Relations between 5-ht receptor 2 and serotonin

Publication Sentence Publish Date Extraction Date Species
D A McCormick, H C Pap. Noradrenergic and serotonergic modulation of a hyperpolarization-activated cation current in thalamic relay neurones. The Journal of physiology. vol 431. 1991-08-22. PMID:1712844. the response to 5-ht was blocked by the 5-ht1 and 5-ht2 antagonist methysergide, but not by the 5-ht2 antagonist ritanserin. 1991-08-22 2023-08-11 cat
J A Apu. The 5-HT2 receptor in brain: recent biochemical and molecular biological developments and new perspectives in its regulation. Pharmacological research. vol 23. issue 3. 1991-08-15. PMID:2068047. recent studies suggested that 5-ht itself might not represent the endogenous ligand for the 5-ht2 receptor. 1991-08-15 2023-08-11 Not clear
G Nowak, J Dulinsk. Effect of repeated treatment with electroconvulsive shock (ECS) on serotonin receptor density and turnover in the rat cerebral cortex. Pharmacology, biochemistry, and behavior. vol 38. issue 3. 1991-08-13. PMID:2068209. repeated treatment with ecs produced an increase in the density of 5-ht1a and tended to increase the specific binding of 5-ht2 serotonin receptors. 1991-08-13 2023-08-11 rat
G Nowak, J Dulinsk. Effect of repeated treatment with electroconvulsive shock (ECS) on serotonin receptor density and turnover in the rat cerebral cortex. Pharmacology, biochemistry, and behavior. vol 38. issue 3. 1991-08-13. PMID:2068209. these results are in agreement with previous studies which indicate that repeated ecs treatment up-regulates 5-ht2 receptors and support the contention that 5-ht1a receptors are up-regulated after repeated treatment with ecs; moreover, these data demonstrate that the dynamic characteristics (turnover rates) of serotonin receptors (5-ht1a, 5-ht2) are unaffected after repeated ecs administration. 1991-08-13 2023-08-11 rat
D H Bobker, J T William. Cocaine and amphetamine interact at 5-HT synapses through distinct mechanisms in guinea-pig prepositus hypoglossi. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 11. issue 7. 1991-08-12. PMID:2066779. the hyperpolarization was most likely caused by the evoked release of 5-ht, while the depolarization may have been due to a direct effect of amphetamine on 5-ht2 receptors. 1991-08-12 2023-08-11 Not clear
H Nishio, Y Ikegami, T Segaw. Fluorescence digital image analysis of serotonin-induced calcium oscillations in single blood platelets. Cell calcium. vol 12. issue 2-3. 1991-08-08. PMID:2059992. this effect of 5-ht was diminished when cacl2 was omitted from the medium, and was antagonized by 1 microm ketanserin, a specific 5-ht2 receptor antagonist. 1991-08-08 2023-08-11 rabbit
H Nishio, Y Ikegami, T Segaw. Fluorescence digital image analysis of serotonin-induced calcium oscillations in single blood platelets. Cell calcium. vol 12. issue 2-3. 1991-08-08. PMID:2059992. furthermore, doi, a specific 5-ht2 agonist, had the same effect as 5-ht at lower concentration. 1991-08-08 2023-08-11 rabbit
Z S Radic, M K O'Donohoe, L B Schwartz, A D Stein, E M Mikat, R L McCann, P O Hage. Alterations in serotonergic receptor expression in experimental vein grafts. Journal of vascular surgery. vol 14. issue 1. 1991-08-08. PMID:2061959. preincubation with ketanserin, a 5-ht2 and alpha 1-adrenergic antagonist, produced a concentration-dependent rightward shift in the 5-ht dose-response curve. 1991-08-08 2023-08-11 rabbit
A Verheyen, F Lauwers, E Vlaminckx, L Wouters, F de Clerc. Oversensitivity to serotonin of the collateralized vascular bed in rat hindquarters: mechanisms of increased vasoconstriction. European journal of pharmacology. vol 194. issue 2-3. 1991-08-02. PMID:2060602. vasoconstriction induced by serotonin was inhibited by 5-ht2 antagonists. 1991-08-02 2023-08-11 rat
A Verheyen, F Lauwers, E Vlaminckx, L Wouters, F de Clerc. Oversensitivity to serotonin of the collateralized vascular bed in rat hindquarters: mechanisms of increased vasoconstriction. European journal of pharmacology. vol 194. issue 2-3. 1991-08-02. PMID:2060602. this resetting of reactivity to serotonin is due to the specific vascular structure as well as to an increased 5-ht2 receptor-mediated sensitivity. 1991-08-02 2023-08-11 rat
B S Neal, R B Messing, S B Sparbe. Long-term effects of neonatal exposure to isobutylmethylxanthine. II. Attenuation of acute morphine withdrawal in mature rats. Psychopharmacology. vol 103. issue 3. 1991-08-01. PMID:1711704. because coadministration of mianserin prevented the effects of ibmx, 5-ht and 5-ht2 receptors are implicated in these effects. 1991-08-01 2023-08-11 rat
H H Berendsen, C L Broekkamp, A M van Delf. Depletion of brain serotonin differently affects behaviors induced by 5HT1A, 5HT1C, and 5HT2 receptor activation in rats. Behavioral and neural biology. vol 55. issue 2. 1991-08-01. PMID:1829353. depletion of brain serotonin differently affects behaviors induced by 5ht1a, 5ht1c, and 5ht2 receptor activation in rats. 1991-08-01 2023-08-11 human
H H Berendsen, C L Broekkamp, A M van Delf. Depletion of brain serotonin differently affects behaviors induced by 5HT1A, 5HT1C, and 5HT2 receptor activation in rats. Behavioral and neural biology. vol 55. issue 2. 1991-08-01. PMID:1829353. 5-hydroxytryptamine (5ht)-depleted rats were subjected to behavioral experiments in which the response to activation of 5ht1a, 5ht1c, and 5ht2 receptor subtypes was measured. 1991-08-01 2023-08-11 human
H I Jacoby, A C Bonfilio, R B Raff. Central and peripheral administration of serotonin produces opposite effects on mouse colonic propulsive motility. Neuroscience letters. vol 122. issue 1. 1991-08-01. PMID:2057128. administration was produced by 8-oh-dpat (5-ht1a), ru-24969 (5-ht1b), and 2-methyl serotonin (5-ht3), but not doi (5-ht2) which augmented propulsion. 1991-08-01 2023-08-11 mouse
P E Pérgola, R H Alpe. Vasopressin and autonomic mechanisms mediate cardiovascular actions of central serotonin. The American journal of physiology. vol 260. issue 6 Pt 2. 1991-08-01. PMID:2058745. the selective 5-ht2 antagonist ly 53857 abolished the increase in map and the bradycardia elicited by 5-ht. 1991-08-01 2023-08-11 rat
D T Chalmers, J McCulloc. Alterations in neurotransmitter receptors and glucose use after unilateral orbital enucleation. Brain research. vol 540. issue 1-2. 1991-07-31. PMID:1675915. using quantitative autoradiography, the effect of unilateral orbital enucleation on [3h]5-ht, [3h]ketanserin, [3h]quinuclidinyl benilate (qnb) and [3h]muscimol binding to 5-ht1, 5-ht2, muscarinic and gabaa receptors has been examined within anatomical components of the visual pathway at 4 time points up to 20 days after the lesion. 1991-07-31 2023-08-11 rat
L L Devaud, E B Hollingswort. Effects of the 5-HT2 receptor antagonist, ritanserin, on biogenic amines in the rat nucleus accumbens. European journal of pharmacology. vol 192. issue 3. 1991-07-31. PMID:1675992. these data show that selective 5-ht2 receptor antagonism modulates da as well as 5-ht neurotransmission and adds support to the suggestion that 5-ht/da interactions may be important in the treatment of psychoses. 1991-07-31 2023-08-11 rat
N A Darmani, B R Martin, U Pandey, R A Glenno. Inhibition of 5-HT2 receptor-mediated head-twitch response by cocaine via indirect stimulation of adrenergic alpha 2 and serotonergic 5-HT1A receptors. Pharmacology, biochemistry, and behavior. vol 38. issue 2. 1991-07-31. PMID:1676173. the present results suggest that cocaine inhibits 5-ht2 receptor function by increasing the synaptic concentration of norepinephrine and serotonin via inhibition of their uptake and thus indirectly stimulating the respective inhibitory adrenergic alpha 2 and serotonergic 5-ht1a receptors. 1991-07-31 2023-08-11 mouse
T Crisp, J L Stafinsky, L J Spanos, M Uram, V C Perni, H B Donepud. Analgesic effects of serotonin and receptor-selective serotonin agonists in the rat spinal cord. General pharmacology. vol 22. issue 2. 1991-07-31. PMID:1829046. the finding that ritanserin reversed 5-ht-induced elevations in hpl suggests that the 5-ht2 site is primarily responsible for mediating the spinal antinociceptive effects of 5-ht on the hot plate test. 1991-07-31 2023-08-11 rat
T Takahashi, H Hisa, S Sato. Serotonin-induced renin release in the dog kidney. European journal of pharmacology. vol 193. issue 3. 1991-07-31. PMID:1905236. the renin release induced by 5-ht was suppressed during intrarenal arterial infusion of a 5-ht1 and 5-ht2 antagonist, methysergide (30 micrograms/kg per min), or a selective 5-ht2 antagonist, ketanserin (3 micrograms/kg per min). 1991-07-31 2023-08-11 dog