All Relations between 5-ht receptor 4 and serotonin

Reference Sentence Publish Date Extraction Date Species
Gary M Mawe, Molly Hurd, Grant W Hennig, Brigitte Lavoi. Epithelial 5-HT Advances in experimental medicine and biology vol 1383 issue 2022 36587170 epithelial 5-ht because of their importance in the regulation of gut functions, several therapeutic targets involving serotonin-related proteins have been developed or repurposed to treat motility disorders, including serotonin transporter inhibitors, tryptophan hydroxylase blockers, 5-ht3 antagonists, and 5-ht4 agonists. 2022-12-31 2023-01-05 Not clear
Evguenia Makovkina, Benjamin D Brody, Charles Shaffe. Possible association of 5-HT4 receptor agonist prucalopride in a 52-year-old man with an index manic episode. Bipolar disorders vol issue 2022 35950919 prucalopride is a selective 5-hydroxytryptamine type 4 (5-ht4) receptor agonist approved for chronic idiopathic constipation in adults. 2022-08-11 2022-08-15 Not clear
Susannah E Murphy, Angharad N de Cates, Amy L Gillespie, Beata R Godlewska, Jessica C Scaife, Lucy C Wright, Philip J Cowen, Catherine J Harme. Translating the promise of 5HT Psychological medicine vol 51 issue 7 2021 32241310 translating the promise of 5ht animal experimental studies suggest that 5-ht4 receptor activation holds promise as a novel target for the treatment of depression and cognitive impairment. 2021-11-30 2022-01-13 Not clear
Nargol Ahmadi-Mahmoodabadi, Masoumeh Emamghoreishi, Mohammad Nasehi, Mohammad-Reza Zarrindas. The bidirectional effect of prelimbic 5-hydroxytryptamine type-4 (5-HT4) receptors on ACPA-mediated aversive memory impairment in adult male Sprague-Dawley rats. Iranian journal of basic medical sciences vol 24 issue 6 2021 34630949 the bidirectional effect of prelimbic 5-hydroxytryptamine type-4 (5-ht4) receptors on acpa-mediated aversive memory impairment in adult male sprague-dawley rats. 2021-10-12 2022-01-13 Not clear
Remzi Karayol, Lucian Medrihan, Jennifer L Warner-Schmidt, Ben W Fait, Meghana N Rao, Eva B Holzner, Paul Greengard, Nathaniel Heintz, Eric F Schmid. Serotonin receptor 4 in the hippocampus modulates mood and anxiety. Molecular psychiatry vol 26 issue 6 2021 33441982 serotonin receptor 4 (5-ht 2021-10-11 2022-01-13 Not clear
Franziska E M\\xc3\\xbcller, Sophie K Schade, Volodymyr Cherkas, Laura Stopper, Bj\\xc3\\xb6rn Breithausen, Daniel Minge, Hristo Varbanov, Christian Wahl-Schott, Svitlana Antoniuk, Catia Domingos, Val\\xc3\\xa9rie Compan, Frank Kirchhoff, Christian Henneberger, Evgeni Ponimaskin, Andre Zeu. Serotonin receptor 4 regulates hippocampal astrocyte morphology and function. Glia vol 69 issue 4 2021 33156956 here we demonstrated that the serotonin receptor 4 (5-ht 2021-09-20 2022-01-13 Not clear
Susannah E Murphy, Lucy C Wright, Michael Browning, Philip J Cowen, Catherine J Harme. A role for 5-HT Psychological medicine vol 50 issue 16 2021 31615585 a role for 5-ht 5-ht4 receptor stimulation has pro-cognitive and antidepressant-like effects in animal experimental studies; however, this pharmacological approach has not yet been tested in humans. 2021-09-06 2022-01-13 Not clear
Nadine Tod, Gabrielle Stalder, Hanna Rauch, Stefan Boehmdorfer, Anna Haw, Hanno Gerritsmann, Johanna Painer, Leith Meye. Investigation of cardiorespiratory effects of the selective 5-HT4 agonist BIMU-8 in etorphine-immobilised goats (Capra aegagrus hircus) in a randomized, blinded and controlled trial. The Veterinary record vol 189 issue 1 2021 33908044 we therefore aimed to determine whether the selective 5-hydroxytryptamine receptor 4 (5-ht4) agonist, bimu-8, reverses opioid-induced respiratory compromise in etorphine-immobilised goats. 2021-09-01 2022-01-13 Not clear
Ji Taek Hon. Current Opinion on Prucalopride in Gastroparesis and Chronic Constipation Treatment: A Focus on Patient Selection and Safety. Therapeutics and clinical risk management vol 17 issue 2021 34135588 prucalopride is a third-generation, highly selective 5-hydroxytryptamine 4 (5-ht4) receptor agonist. 2021-06-19 2022-01-13 Not clear
Antoine-Guy Lopez, C\\xc3\\xa9line Duparc, Alexandre Naccache, Mireille Castanet, Herv\\xc3\\xa9 Lefebvre, Estelle Louise. Role of Mast Cells in the Control of Aldosterone Secretion. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme vol 52 issue 6 2021 32215882 in human, mast cell degranulation stimulates aldosterone synthesis through the release of serotonin (5-ht) and activation of 5-ht4 receptors. 2021-04-02 2022-01-13 Not clear
Dasiel O Borroto-Escuela, Xiang Li, Alexander O Tarakanov, David Savelli, Manuel Narv\\xc3\\xa1ez, Kirill Shumilov, Yuniesky Andrade-Talavera, Antonio Jimenez-Beristain, Bartosz Pomierny, Zaida D\\xc3\\xadaz-Cabiale, Riccardo Cuppini, Patrizia Ambrogini, Maria Lindskog, Kjell Fux. Existence of Brain 5-HT1A-5-HT2A Isoreceptor Complexes with Antagonistic Allosteric Receptor-Receptor Interactions Regulating 5-HT1A Receptor Recognition. ACS omega vol 2 issue 8 2020 28920103 there are many 5-ht subtypes involved; some need to be blocked (e.g., 5-ht2a, 5-ht3, and 5-ht7), whereas others need to be activated (e.g., postjunctional 5-ht1a and 5-ht4). 2020-10-01 2022-01-13 Not clear
Asim Tameez Ud Din, Ameer H Khan, Hamza Bajwa, Muhammad Haisum Maqsood, Mustafa N Mali. Clinical Efficacy and Safety Profile of Prucalopride in Chronic Idiopathic Constipation. Cureus vol 11 issue 4 2020 31218146 prucalopride is a prokinetic agent which works at the 5-hydroxytryptamine receptor 4 (5-ht4) as an agonist with greater receptor selectivity. 2020-09-29 2022-01-13 Not clear
Julie Le Mestre, C\\xc3\\xa9line Duparc, Yves Reznik, Fid\\xc3\\xa9line Bonnet-Serrano, Philippe Touraine, Olivier Chabre, Jacques Young, Mari Suzuki, Mathilde Sibony, Fran\\xc3\\xa7oise Gobet, Constantine A Stratakis, G\\xc3\\xa9rald Raverot, J\\xc3\\xa9r\\xc3\\xb4me Bertherat, Herv\\xc3\\xa9 Lefebvre, Estelle Louise. Illicit Upregulation of Serotonin Signaling Pathway in Adrenals of Patients With High Plasma or Intra-Adrenal ACTH Levels. The Journal of clinical endocrinology and metabolism vol 104 issue 11 2020 31074783 in primary pigmented nodular adrenocortical disease cells, activation of the camp/protein kinase a (pka) pathway by prkar1a mutations triggers upregulation of the 5-ht synthesizing enzyme tryptophan hydroxylase (tph) and the 5-ht4, 5-ht6, and 5-ht7 receptors. 2020-06-01 2022-01-13 Not clear
Jiqiang Guo, Huaxia Ding, Zhuangwei Lv, Junna Jiao, Hui Wang, Yanhong J. Down-regulation effects of IFN-\\xce\\xb1 on p11, 5-htr1b and 5-HTR4 protein levels were affected by NH Journal of biosciences vol 44 issue 4 2020 31502579 down-regulation effects of ifn-\xce\xb1 on p11, 5-htr1b and 5-htr4 protein levels were affected by nh in previous studies, we found interferon-\xce\xb1 (ifn-\xce\xb1) could reduce protein levels of p11, 5-hydroxytryptamine receptor 1b (5-ht1b) and 5-hydroxytryptamine receptor 4 (5-ht4), but does not influence their messenger rna levels in sh-sy5y cells. 2020-01-30 2022-01-13 Not clear
Kyeong Seop Kim, Mi Ae Kim, Young Chang Soh. Molecular characterization, expression analysis, and functional properties of multiple 5-hydroxytryptamine receptors in Pacific abalone (Haliotis discus hannai). General and comparative endocrinology vol 276 issue 2019 30849410 a phylogenetic analysis indicated that the molluskan 5-ht receptors are largely classified into four major clades: 5-ht1/5/7, 5-ht2, 5-ht4, and 5-ht6. 2019-05-17 2022-01-13 Not clear
Miriam A Snider, David L Harmon, James L Klot. Pharmacologic assessment of bovine ruminal and mesenteric vascular serotonin receptor populations. Journal of animal science vol 96 issue 4 2018 29471490 to determine what 5-ht receptors are involved in vasoconstriction of gut vasculature, contractility of ruminal and mesenteric arteries and veins collected from cattle was evaluated in the presence of agonists selective for 5-ht1b (cp 93129), 5-ht1d (l-694, 247), 5-ht2a (tcb-2), 5-ht2b (bw 723c86), 5-ht4 (bimu-8), and 5-ht7 (lp 44) receptors. 2018-10-09 2022-01-13 Not clear
J E Dalziel, W Young, P Bercik, N J Spencer, L J Ryan, K E Dunstan, C M Lloyd-West, P K Gopal, N W Haggarty, N C Ro. Tracking gastrointestinal transit of solids in aged rats as pharmacological models of chronic dysmotility. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society vol 28 issue 8 2018 27028044 the 5-hydroxytryptamine type 4 (5-ht4 ) receptor agonist prucalopride was used to accelerate transit, and the opioid agonist loperamide was used to delay transit. 2018-02-12 2022-01-12 Not clear
R Forc\\xc3\\xa9n, E Latorre, J Pardo, A I Alcalde, M D Murillo, L Gras. Toll-like receptors 2 and 4 exert opposite effects on the contractile response induced by serotonin in mouse colon: role of serotonin receptors. Experimental physiology vol 101 issue 8 2018 27282784 in wt, tlr2(-/-) and tlr2/4 dko mice, 5-ht2 , 5-ht3 , 5-ht4 and 5-ht7 receptor antagonists reduced or blocked the contractile response evoked by 5-ht. 2018-01-01 2022-01-12 Not clear
Emanuel Berk, Torsten Christ, Simon Schwarz, Ursula Ravens, Michael Knaut, Alberto J Kauman. In permanent atrial fibrillation, PDE3 reduces force responses to 5-HT, but PDE3 and PDE4 do not cause the blunting of atrial arrhythmias. British journal of pharmacology vol 173 issue 16 2017 27238373 5-ht increases force and l-type ca(2) (+) current (ica,l ) and causes arrhythmias through 5-ht4 receptors in human atrium. 2017-10-12 2022-01-12 Not clear
D J David, A M Gardie. [The pharmacological basis of the serotonin system: Application to antidepressant response]. L'Encephale vol 42 issue 3 2017 27112704 physiological effects of 5-ht are mediated by about 15\xc2\xa0serotoninergic receptors grouped into seven broad families (5-ht1, 5-ht2, 5-ht3, 5-ht4, 5-ht5, 5-ht6, 5-ht7\xc2\xa0receptor families). 2017-09-20 2022-01-12 Not clear
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