| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Suzuki, N Iwata, Y Kitamura, T Kitajima, Y Yamanouchi, M Ikeda, T Nishiyama, N Kamatani, N Ozak. Association of a haplotype in the serotonin 5-HT4 receptor gene (HTR4) with Japanese schizophrenia. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 121B. issue 1. 2003-09-17. PMID:12898568. |
association of a haplotype in the serotonin 5-ht4 receptor gene (htr4) with japanese schizophrenia. |
2003-09-17 |
2023-08-12 |
Not clear |
| Margaret Heitkemper, Monica Jarrett, Eleanor F Bond, Lin Chan. Impact of sex and gender on irritable bowel syndrome. Biological research for nursing. vol 5. issue 1. 2003-09-02. PMID:12886671. |
fourth, serotonin (5-ht3) receptor antagonist and 5-ht4 partial agonist drugs appear to more effectively diminish reports of bowel pattern disruption in women with ibs as compared to men. |
2003-09-02 |
2023-08-12 |
Not clear |
| M Tonini, R De Giorgio, V Spelta, G Bassotti, A Di Nucci, L Anselmi, B Balestra, F De Pont. 5-HT4 receptors contribute to the motor stimulating effect of levosulpiride in the guinea-pig gastrointestinal tract. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver. vol 35. issue 4. 2003-07-31. PMID:12801035. |
however, for other benzamide derivatives, such as cisapride and mosapride, agonism towards serotonin 5-ht4 receptors is considered the main mechanism leading to gastrointestinal prokinesia. |
2003-07-31 |
2023-08-12 |
Not clear |
| Till Manzke, Ulf Guenther, Evgeni G Ponimaskin, Miriam Haller, Mathias Dutschmann, Stephan Schwarzacher, Diethelm W Richte. 5-HT4(a) receptors avert opioid-induced breathing depression without loss of analgesia. Science (New York, N.Y.). vol 301. issue 5630. 2003-07-23. PMID:12855812. |
we report that serotonin 4(a) [5-ht4(a)] receptors are strongly expressed in respiratory pbc neurons and that their selective activation protects spontaneous respiratory activity. |
2003-07-23 |
2023-08-12 |
rat |
| Frank Lezoualc'h, Sylvain J Rober. The serotonin 5-HT4 receptor and the amyloid precursor protein processing. Experimental gerontology. vol 38. issue 1-2. 2003-05-12. PMID:12543273. |
the serotonin 5-ht4 receptor and the amyloid precursor protein processing. |
2003-05-12 |
2023-08-12 |
human |
| Noriaki Makimoto, Yasuko Sakurai-Yamashita, Akira Furuichi, Shunsuke Kawakami, Akihito Enjoji, Takashi Kanematsu, Kohtaro Taniya. In vivo assessment of acceleration of motor activity associated with acetylcholine release via 5-hydroxytryptamine4 receptor in dog intestine. Japanese journal of pharmacology. vol 90. issue 1. 2003-04-15. PMID:12396025. |
thus, in the whole body of dogs, 5-ht and mosapride accelerated the intestinal motor activity due to the increases in ach release mediated by stimulation of the 5-ht4 receptor. |
2003-04-15 |
2023-08-12 |
dog |
| Clementina Bianchi, Donata Rodi, Silvia Marino, Lorenzo Beani, Anna Siniscalch. Dual effects of 5-HT4 receptor activation on GABA release from guinea pig hippocampal slices. Neuroreport. vol 13. issue 17. 2003-04-15. PMID:12488792. |
these results provide evidence that serotonin exerts a complex modulation on the gabaergic system, via 5-ht4 receptors, and suggest that the amine releases acetylcholine which, in turn, bidirectionally modulates gaba release. |
2003-04-15 |
2023-08-12 |
Not clear |
| Jens Henrik Norum, Kent Hart, Finn Olav Lev. Ras-dependent ERK activation by the human G(s)-coupled serotonin receptors 5-HT4(b) and 5-HT7(a). The Journal of biological chemistry. vol 278. issue 5. 2003-04-03. PMID:12446729. |
ras-dependent erk activation by the human g(s)-coupled serotonin receptors 5-ht4(b) and 5-ht7(a). |
2003-04-03 |
2023-08-12 |
human |
| V Bozon, E Di Scala, P Eftekhari, J Hoebeke, F Lezoualc'h, R Fischmeister, J Argiba. Agonist-like activity of antibodies directed against the second extracellular loop of the human cardiac serotonin 5-HT4(e) receptor in transfected COS-7 cells. Receptors & channels. vol 8. issue 2. 2003-03-24. PMID:12448792. |
agonist-like activity of antibodies directed against the second extracellular loop of the human cardiac serotonin 5-ht4(e) receptor in transfected cos-7 cells. |
2003-03-24 |
2023-08-12 |
human |
| Akira Yoshida, Yasuko S-Yamashita, Muneshige Kaibara, Kohtaro Taniyama, Nobuyuki Tanak. 5-Hydroxytryptamine receptors, especially the 5-HT4 receptor, in guinea pig urinary bladder. Japanese journal of pharmacology. vol 89. issue 4. 2003-03-18. PMID:12233812. |
5-hydroxytryptamine receptors, especially the 5-ht4 receptor, in guinea pig urinary bladder. |
2003-03-18 |
2023-08-12 |
Not clear |
| Akira Yoshida, Yasuko S-Yamashita, Muneshige Kaibara, Kohtaro Taniyama, Nobuyuki Tanak. 5-Hydroxytryptamine receptors, especially the 5-HT4 receptor, in guinea pig urinary bladder. Japanese journal of pharmacology. vol 89. issue 4. 2003-03-18. PMID:12233812. |
the function of 5-hydroxytryptamine (5-ht) receptors, especially the 5-ht4 receptor, in the urinary bladder were examined in preparations isolated from the guinea pig by in vitro receptor autoradiography and determinations of mechanical activity and acetylcholine (ach) release. |
2003-03-18 |
2023-08-12 |
Not clear |
| Akira Yoshida, Yasuko S-Yamashita, Muneshige Kaibara, Kohtaro Taniyama, Nobuyuki Tanak. 5-Hydroxytryptamine receptors, especially the 5-HT4 receptor, in guinea pig urinary bladder. Japanese journal of pharmacology. vol 89. issue 4. 2003-03-18. PMID:12233812. |
thus, the contractile response to 5-ht was mediated by activations of 5-ht2, 5-ht3 and 5-ht4 receptors. |
2003-03-18 |
2023-08-12 |
Not clear |
| Akira Yoshida, Yasuko S-Yamashita, Muneshige Kaibara, Kohtaro Taniyama, Nobuyuki Tanak. 5-Hydroxytryptamine receptors, especially the 5-HT4 receptor, in guinea pig urinary bladder. Japanese journal of pharmacology. vol 89. issue 4. 2003-03-18. PMID:12233812. |
the 5-ht4 as well as 5-ht3 receptor may be a property of low affinity to 5-ht and located on the cholinergic neurons. |
2003-03-18 |
2023-08-12 |
Not clear |
| Y S R Krishnaiah, T K Murthy, D G Sankar, V Satyanarayan. A validated RP-HPLC method for the determination of mosapride citrate in bulk drug samples and pharmaceutical formulations. Die Pharmazie. vol 57. issue 12. 2003-03-12. PMID:12561242. |
mosapride citrate, a selective serotonin 5-ht4 agonist, is a novel and potent gastroprokinetic drug. |
2003-03-12 |
2023-08-12 |
Not clear |
| Richard A Feelders, Steven W J Lamberts, Leo J Hofland, Peter M van Koetsveld, Miriam Verhoef-Post, Axel P N Themmen, Frank H de Jong, H Jaap Bonjer, Adrian J Clark, Aart-Jan van der Lely, Wouter W de Herde. Luteinizing hormone (LH)-responsive Cushing's syndrome: the demonstration of LH receptor messenger ribonucleic acid in hyperplastic adrenal cells, which respond to chorionic gonadotropin and serotonin agonists in vitro. The Journal of clinical endocrinology and metabolism. vol 88. issue 1. 2003-02-11. PMID:12519858. |
this variant is further characterized by adrenal responsiveness to 5-ht4 receptor agonists, possibly pointing to an interaction between lh and serotonin in the regulation of cortisol secretion. |
2003-02-11 |
2023-08-12 |
human |
| Hisayuki Uneyama, Akira Niijima, Tatsuro Tanaka, Kunio Tori. Receptor subtype specific activation of the rat gastric vagal afferent fibers to serotonin. Life sciences. vol 72. issue 4-5. 2003-01-27. PMID:12467882. |
the 5-ht(3/4) agonist, cisapride partially activated the vagus nerve, but the 5-ht4 agonist, rs6733 had no effect on the vagal afferent activity. |
2003-01-27 |
2023-08-12 |
rat |
| A Schikowski, Michael Thewissen, C Mathis, H-G Ross, P Enc. Serotonin type-4 receptors modulate the sensitivity of intramural mechanoreceptive afferents of the cat rectum. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. vol 14. issue 3. 2002-12-11. PMID:12061906. |
it has been suggested that serotonin (5-hydroxytryptamine) type-4 (5-ht4) receptors modulate the sensitivity of intrinsic afferents of the intestinal mucosa. |
2002-12-11 |
2023-08-12 |
cat |
| Guillaume Lucas, Guy Debonne. 5-HT4 receptors exert a frequency-related facilitatory control on dorsal raphé nucleus 5-HT neuronal activity. The European journal of neuroscience. vol 16. issue 5. 2002-12-09. PMID:12372017. |
5-ht4 receptors exert a frequency-related facilitatory control on dorsal raphé nucleus 5-ht neuronal activity. |
2002-12-09 |
2023-08-12 |
rat |
| Guillaume Lucas, Guy Debonne. 5-HT4 receptors exert a frequency-related facilitatory control on dorsal raphé nucleus 5-HT neuronal activity. The European journal of neuroscience. vol 16. issue 5. 2002-12-09. PMID:12372017. |
we investigated, using single-unit recordings in chloral hydrate-anaesthetized rats, the role of serotonin 4 (5-ht4) receptors in the control of dorsal raphé nucleus (drn) 5-ht neuron activity. |
2002-12-09 |
2023-08-12 |
rat |
| Guillaume Lucas, Guy Debonne. 5-HT4 receptors exert a frequency-related facilitatory control on dorsal raphé nucleus 5-HT neuronal activity. The European journal of neuroscience. vol 16. issue 5. 2002-12-09. PMID:12372017. |
the firing rate of responding 5-ht neurons was enhanced dose-dependently by cisapride (+47 and +94% at 500 and 1000 micro g/kg, respectively), an effect abolished by gr 125487 (500 micro g/kg) and reduced by the 5-ht4 antagonist, sdz 205557 (500 micro g/kg, i.v). |
2002-12-09 |
2023-08-12 |
rat |