| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| I Van den Wyngaert, W Gommeren, P Verhasselt, M Jurzak, J Leysen, W Luyten, E Bende. Cloning and expression of a human serotonin 5-HT4 receptor cDNA. Journal of neurochemistry. vol 69. issue 5. 1997-11-20. PMID:9349523. |
using a combination of library screening and nested pcr based on a partial human serotonin 5-ht4 receptor sequence, we have cloned the complete coding region for a human 5-ht4 receptor. |
1997-11-20 |
2023-08-12 |
human |
| H Lefebvre, M Dhib, M Godin, V Contesse, C Delarue, M Rieu, L M Wolf, H Vaudry, J M Kuh. Effect of the serotonin 5-HT4 receptor agonist cisapride on aldosterone secretion in corticotropic insufficiency and primary hyperaldosteronism. Neuroendocrinology. vol 66. issue 3. 1997-11-07. PMID:9380281. |
effect of the serotonin 5-ht4 receptor agonist cisapride on aldosterone secretion in corticotropic insufficiency and primary hyperaldosteronism. |
1997-11-07 |
2023-08-12 |
human |
| H Lefebvre, M Dhib, M Godin, V Contesse, C Delarue, M Rieu, L M Wolf, H Vaudry, J M Kuh. Effect of the serotonin 5-HT4 receptor agonist cisapride on aldosterone secretion in corticotropic insufficiency and primary hyperaldosteronism. Neuroendocrinology. vol 66. issue 3. 1997-11-07. PMID:9380281. |
serotonin (5-ht) stimulates aldosterone secretion in man through activation of 5-ht4 receptors coupled to adenylyl cyclase via a gs regulatory protein. |
1997-11-07 |
2023-08-12 |
human |
| H Lefebvre, M Dhib, M Godin, V Contesse, C Delarue, M Rieu, L M Wolf, H Vaudry, J M Kuh. Effect of the serotonin 5-HT4 receptor agonist cisapride on aldosterone secretion in corticotropic insufficiency and primary hyperaldosteronism. Neuroendocrinology. vol 66. issue 3. 1997-11-07. PMID:9380281. |
in order to examine the possible influence of acth and ang ii on the responsiveness of human glomerulosa cells to 5-ht, we have investigated the effect of cisapride, a 5-ht4 receptor agonist, on plasma aldosterone in patients with suppressed plasma acth, i.e. |
1997-11-07 |
2023-08-12 |
human |
| C G Cardenas, L P Del Mar, B Y Cooper, R S Scrogg. 5HT4 receptors couple positively to tetrodotoxin-insensitive sodium channels in a subpopulation of capsaicin-sensitive rat sensory neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 19. 1997-10-15. PMID:9295364. |
the 5ht receptor involved resembled the 5ht4 subtype. |
1997-10-15 |
2023-08-12 |
rat |
| M Yamano, H Ito, K Miyat. Species differences in the 5-hydroxytryptamine-induced contraction in the isolated distal ileum. Japanese journal of pharmacology. vol 74. issue 3. 1997-10-09. PMID:9268087. |
furthermore, 5-ht4 receptors may participate in the relaxation elicited by 5-ht in rats. |
1997-10-09 |
2023-08-12 |
rat |
| S Letty, R Child, A Dumuis, A Pantaloni, J Bockaert, G Rondoui. 5-HT4 receptors improve social olfactory memory in the rat. Neuropharmacology. vol 36. issue 4-5. 1997-09-15. PMID:9225294. |
serotonin (5-ht) is involved in a large variety of physiological functions and it appears now that it could play a role in cognitive processes through the activation of 5-ht4 receptors. |
1997-09-15 |
2023-08-12 |
rat |
| D J Fontana, S E Daniels, E H Wong, R D Clark, R M Egle. The effects of novel, selective 5-hydroxytryptamine (5-HT)4 receptor ligands in rat spatial navigation. Neuropharmacology. vol 36. issue 4-5. 1997-09-15. PMID:9225295. |
activation of central 5-hydroxytryptamine (5-ht4) receptors may enhance cognitive performance. |
1997-09-15 |
2023-08-12 |
rat |
| O Blondel, G Vandecasteele, M Gastineau, S Leclerc, Y Dahmoune, M Langlois, R Fischmeiste. Molecular and functional characterization of a 5-HT4 receptor cloned from human atrium. FEBS letters. vol 412. issue 3. 1997-09-11. PMID:9276448. |
5-hydroxytryptamine (5-ht) has been shown to exert positive inotropic, chronotropic, and lusitropic effects and to stimulate the l-type calcium channel current (i(ca)) in human atrial tissue through activation of the pharmacologically defined 5-ht4 receptor subtype. |
1997-09-11 |
2023-08-12 |
human |
| O Blondel, G Vandecasteele, M Gastineau, S Leclerc, Y Dahmoune, M Langlois, R Fischmeiste. Molecular and functional characterization of a 5-HT4 receptor cloned from human atrium. FEBS letters. vol 412. issue 3. 1997-09-11. PMID:9276448. |
we conclude that h5-ht4a likely mediates the effects of 5-ht in human atrium and may differ from 5-ht4 receptor isoforms present in the brain and gi tract. |
1997-09-11 |
2023-08-12 |
human |
| M Gobbi, D Crespi, M C Foddi, C Fracasso, L Mancini, L Parotti, T Mennin. Effects of chronic treatment with fluoxetine and citalopram on 5-HT uptake, 5-HT1B autoreceptors, 5-HT3 and 5-HT4 receptors in rats. Naunyn-Schmiedeberg's archives of pharmacology. vol 356. issue 1. 1997-09-05. PMID:9228186. |
effects of chronic treatment with fluoxetine and citalopram on 5-ht uptake, 5-ht1b autoreceptors, 5-ht3 and 5-ht4 receptors in rats. |
1997-09-05 |
2023-08-12 |
rat |
| M Gobbi, D Crespi, M C Foddi, C Fracasso, L Mancini, L Parotti, T Mennin. Effects of chronic treatment with fluoxetine and citalopram on 5-HT uptake, 5-HT1B autoreceptors, 5-HT3 and 5-HT4 receptors in rats. Naunyn-Schmiedeberg's archives of pharmacology. vol 356. issue 1. 1997-09-05. PMID:9228186. |
however, our negative data are in agreement with many other published studies, suggesting that adaptive modifications of brain 5-ht transporters, terminal 5-ht1b receptors, 5-ht3 and 5-ht4 receptors may not be a general effect induced by all ssri. |
1997-09-05 |
2023-08-12 |
rat |
| Y Nagakura, H Ito, T Kiso, Y Naitoh, K Miyat. The selective 5-hydroxytryptamine (5-HT)4-receptor agonist RS67506 enhances lower intestinal propulsion in mice. Japanese journal of pharmacology. vol 74. issue 2. 1997-09-03. PMID:9243330. |
interactions of gastrointestinal prokinetic benzamides with 5-hydroxytryptamine (5-ht)3 and 5-ht4 receptors and the relation to their effects on gastrointestinal propulsion were investigated. |
1997-09-03 |
2023-08-12 |
mouse |
| S Graf, S K Sarn. 5-HT-induced colonic contractions: enteric locus of action and receptor subtypes. The American journal of physiology. vol 273. issue 1 Pt 1. 1997-09-03. PMID:9252511. |
prior close intra-arterial infusions of 5-ht1a/5-ht1b, 5-ht2a, 5-ht2c, and 5-ht4 receptor antagonists had no significant effect on the contractile response to 5-ht. |
1997-09-03 |
2023-08-12 |
Not clear |
| M A Plaza, M P Arruebo, M D Murill. Evidence for the involvement of 5-HT4 receptors in the 5-hydroxytryptamine-induced pattern of migrating myoelectric complex in sheep. British journal of pharmacology. vol 120. issue 6. 1997-08-27. PMID:9134228. |
our data show that 5-ht initiates a mmc-like pattern in the gastrointestinal area in sheep through 5-ht4 receptors. |
1997-08-27 |
2023-08-12 |
Not clear |
| C A Rizzi, J Mierau, H Ladinsk. Regulation of plasma aldosterone levels by metoclopramide: a reappraisal of its mechanism from dopaminergic antagonism to serotonergic agonism. Neuropharmacology. vol 36. issue 6. 1997-08-18. PMID:9225303. |
here we briefly review this work and attempt to reassess the action of metoclopramide as an aldosterone secretagogue, from dopamine d2 antagonism to serotonin 5-ht4 partial agonism. |
1997-08-18 |
2023-08-12 |
human |
| A Monge, J Palop, S Pérez, C Oset, B Lashera. Synthesis of thiophene carboxamide derivatives as serotonin 5-HT4 receptor agonists. Farmaco (Societa chimica italiana : 1989). vol 52. issue 2. 1997-08-14. PMID:9181688. |
synthesis of thiophene carboxamide derivatives as serotonin 5-ht4 receptor agonists. |
1997-08-14 |
2023-08-12 |
rat |
| A Monge, J Palop, S Pérez, C Oset, B Lashera. Synthesis of thiophene carboxamide derivatives as serotonin 5-HT4 receptor agonists. Farmaco (Societa chimica italiana : 1989). vol 52. issue 2. 1997-08-14. PMID:9181688. |
new thiophene carboxamide derivatives 3 (a-j) were synthesized as serotonin 5-ht4 receptor agonists. |
1997-08-14 |
2023-08-12 |
rat |
| M T Salvador, M C Rodríguez-Yoldi, A I Alcalde, M J Rodríguez-Yold. 5-HT receptor subtypes involved in the serotonin-induced inhibition of L-leucine absorption in rabbit jejunum. Life sciences. vol 61. issue 3. 1997-08-04. PMID:9217291. |
the 5-ht antagonists, gr 113808a (5-ht4) at 2.5x10(-6) m and ritanserin (5-ht2) and ondansetron (5-ht3) at 2.5x10(-5) m completely blocked the effect of 5-ht. |
1997-08-04 |
2023-08-12 |
rabbit |
| T Kiso, H Ito, K Miyat. Effect of ramosetron on short-circuit current response in rat colonic mucosa. European journal of pharmacology. vol 320. issue 2-3. 1997-07-14. PMID:9059853. |
these results suggest that 5-ht increases isc through the 5-ht3 and 5-ht4 receptors, and that ramosetron is a potent and selective 5-ht3 receptor antagonist in rat colonic mucosa. |
1997-07-14 |
2023-08-12 |
rat |