All Relations between 5-ht receptor 6 and serotonin

Reference Sentence Publish Date Extraction Date Species
Xiaolong Gao, Mo Zhang, Shihui Lin, Mingxin Lyu, Xuan Luo, Weiwei You, Caihuan K. Reproduction strategy of nocturnal marine molluscs: running for love. Integrative zoology vol issue 2023 36609825 after 24 h uninterrupted sampling, the concentration of 5-ht and the expression levels of the 5-ht2 and 5-ht6 receptors in am were significantly higher than those in jm. 2023-01-07 2023-01-08 Not clear
Xiaolong Gao, Mo Zhang, Shihui Lin, Mingxin Lyu, Xuan Luo, Weiwei You, Caihuan K. Reproduction strategy of nocturnal marine molluscs: running for love. Integrative zoology vol issue 2023 36609825 after further injection of 5-ht2 and 5-ht6 receptor antagonists, the concentrations of camp and pka rose again, but the cumulative movement duration and distance of male abalones decreased significantly, showing that 5-ht was involved in the regulation of movement behavior of male abalones through the 5-ht2 and 5-ht6 receptor-activated camp-pka pathways. 2023-01-07 2023-01-08 Not clear
Syed Nasir Abbas Bukhari, Mervat Abdelaziz Elsherif, Kashaf Junaid, Hasan Ejaz, Pravej Alam, Abdul Samad, Rahul D Jawarkar, Vijay H Masan. Perceiving the Concealed and Unreported Pharmacophoric Features of the 5-Hydroxytryptamine Receptor Using Balanced QSAR Analysis. Pharmaceuticals (Basel, Switzerland) vol 15 issue 7 2022 35890133 the 5-hydroxytryptamine receptor 6 (5-ht6) has gained attention as a target for developing therapeutics for alzheimer's disease, schizophrenia, cognitive dysfunctions, anxiety, and depression, to list a few. 2022-07-27 2022-08-08 Not clear
Keita Koizumi, Hideo Nakajim. Serotonin induces the migration of PC12 cells via the serotonin receptor 6/cAMP/ERK pathway. Biomedical reports vol 2 issue 1 2021 24649064 additionally, 5-ht receptor antagonists suggest that 5-ht-induced migration was mediated by serotonin receptor 6 (5-ht 2021-10-21 2022-01-12 Not clear
Qinying Wang, Xiaoxu Dong, Tingting Hu, Chao Qu, Jing Lu, Yue Zhou, Jinsong Li, Gang Pe. Constitutive Activity of Serotonin Receptor 6 Regulates Human Cerebral Organoids Formation and Depression-like Behaviors. Stem cell reports vol 16 issue 1 2021 33357407 serotonin receptor 6 (5-ht 2021-06-07 2022-01-13 Not clear
Julie Le Mestre, C\\xc3\\xa9line Duparc, Yves Reznik, Fid\\xc3\\xa9line Bonnet-Serrano, Philippe Touraine, Olivier Chabre, Jacques Young, Mari Suzuki, Mathilde Sibony, Fran\\xc3\\xa7oise Gobet, Constantine A Stratakis, G\\xc3\\xa9rald Raverot, J\\xc3\\xa9r\\xc3\\xb4me Bertherat, Herv\\xc3\\xa9 Lefebvre, Estelle Louise. Illicit Upregulation of Serotonin Signaling Pathway in Adrenals of Patients With High Plasma or Intra-Adrenal ACTH Levels. The Journal of clinical endocrinology and metabolism vol 104 issue 11 2020 31074783 in primary pigmented nodular adrenocortical disease cells, activation of the camp/protein kinase a (pka) pathway by prkar1a mutations triggers upregulation of the 5-ht synthesizing enzyme tryptophan hydroxylase (tph) and the 5-ht4, 5-ht6, and 5-ht7 receptors. 2020-06-01 2022-01-13 Not clear
Rajiv Radhakrishnan, Nabeel Nabulsi, Edward Gaiser, Jean-Dominique Gallezot, Shannan Henry, Beata Planeta, Shu-Fei Lin, Jim Ropchan, Wendol Williams, Evan Morris, Deepak Cyril D'Souza, Yiyun Huang, Richard E Carson, David Matuske. Age-Related Change in 5-HT Journal of nuclear medicine : official publication, Society of Nuclear Medicine vol 59 issue 9 2019 29626125 age-related change in 5-ht serotonin receptor 6 (5-hydroxytrypamine-6, or 5-ht 2019-07-09 2022-01-13 Not clear
Kyeong Seop Kim, Mi Ae Kim, Young Chang Soh. Molecular characterization, expression analysis, and functional properties of multiple 5-hydroxytryptamine receptors in Pacific abalone (Haliotis discus hannai). General and comparative endocrinology vol 276 issue 2019 30849410 a phylogenetic analysis indicated that the molluskan 5-ht receptors are largely classified into four major clades: 5-ht1/5/7, 5-ht2, 5-ht4, and 5-ht6. 2019-05-17 2022-01-13 Not clear
Changyun Liu, Yuxing Wen, Huapin Huang, Wanhui Lin, Mingzhu Huang, Rong Lin, Ying M. Over-expression of 5-HT6 Receptor and Activated Jab-1/p-c-Jun Play Important Roles in Pilocarpine-Induced Seizures and Learning-Memory Impairment. Journal of molecular neuroscience : MN vol 67 issue 3 2019 30694481 also, serotonin 5-hydroxytryptamine 6 (5-ht6) receptor plays an important role in cognition. 2019-04-15 2022-01-13 Not clear
Alexandre V Ivachtchenko, Yan A Ivanenkov, Mark S Veselov, I M Oku. AVN-322 is a Safe Orally Bio-Available Potent and Highly Selective Antagonist of 5-HT6R with Demonstrated Ability to Improve Impaired Memory in Animal Models. Current Alzheimer research vol 14 issue 3 2017 27829340 in recent years, 5-hydroxytryptamine subtype 6 receptor (5-ht6 receptor, 5- ht6r) has emerged as a promising therapeutic target for the treatment of neuropathological disorders, including alzheimer's disease (ad) and schizophrenia. 2017-10-16 2022-01-13 Not clear
D J David, A M Gardie. [The pharmacological basis of the serotonin system: Application to antidepressant response]. L'Encephale vol 42 issue 3 2017 27112704 physiological effects of 5-ht are mediated by about 15\xc2\xa0serotoninergic receptors grouped into seven broad families (5-ht1, 5-ht2, 5-ht3, 5-ht4, 5-ht5, 5-ht6, 5-ht7\xc2\xa0receptor families). 2017-09-20 2022-01-12 Not clear
Ju-Ryun Na, Dool-Ri Oh, SeulHee Han, Yu-Jin Kim, EunJin Choi, Donghyuck Bae, Dong Hwan Oh, Yoo-Hyun Lee, Sunoh Kim, Woojin Ju. Antistress Effects of Rosa rugosa Thunb. on Total Sleep Deprivation-Induced Anxiety-Like Behavior and Cognitive Dysfunction in Rat: Possible Mechanism of Action of 5-HT6 Receptor Antagonist. Journal of medicinal food vol 19 issue 9 2017 27331439 this study aimed to screen and identify the physiological antistress effects of an extract of r. rugosa (ro) on sleep deprivation-induced anxiety-like behavior and cognitive tests (in vivo) and tested for hippocampal cort and monoamine levels (ex vivo), corticosterone (cort)-induced injury, n-methyl-d-aspartate (nmda) receptor, and serotonin 6 (5-hydroxytryptamine 6, 5-ht6) receptor activities (in vitro) in search of active principles and underlying mechanisms of action. 2017-05-05 2022-01-12 Not clear
Yukihiro Ohno, Saki Shimizu, Kentaro Tokudome, Naofumi Kunisawa, Masashi Sas. New insight into the therapeutic role of the serotonergic system in Parkinson's disease. Progress in neurobiology vol 134 issue 2016 26455457 among 5-ht receptor subtypes, 5-ht1a, 5-ht2, 5-ht3 and 5-ht6 receptors play an important role in modulating extrapyramidal motor disorders. 2016-08-25 2022-01-12 Not clear
Julia T Brouard, Judith V Schweimer, Rachel Houlton, Katherine E Burnham, Philip Qu\\xc3\\xa9r\\xc3\\xa9e, Trevor Shar. Pharmacological Evidence for 5-HT6 Receptor Modulation of 5-HT Neuron Firing in Vivo. ACS chemical neuroscience vol 6 issue 7 2016 25837696 pharmacological evidence for 5-ht6 receptor modulation of 5-ht neuron firing in vivo. 2016-04-19 2022-01-12 Not clear
Julia T Brouard, Judith V Schweimer, Rachel Houlton, Katherine E Burnham, Philip Qu\\xc3\\xa9r\\xc3\\xa9e, Trevor Shar. Pharmacological Evidence for 5-HT6 Receptor Modulation of 5-HT Neuron Firing in Vivo. ACS chemical neuroscience vol 6 issue 7 2016 25837696 accumulating evidence suggests that 5-ht6 receptors may be located and functional in the drn; therefore, 5-ht6 receptor ligands may have potential as novel modulators of 5-ht neurotransmission. 2016-04-19 2022-01-12 Not clear
Julia T Brouard, Judith V Schweimer, Rachel Houlton, Katherine E Burnham, Philip Qu\\xc3\\xa9r\\xc3\\xa9e, Trevor Shar. Pharmacological Evidence for 5-HT6 Receptor Modulation of 5-HT Neuron Firing in Vivo. ACS chemical neuroscience vol 6 issue 7 2016 25837696 administration of the selective 5-ht6 receptor agonist, way-181187, and antagonist, sb-399885, on the firing of 5-ht neurons in the drn in vivo. 2016-04-19 2022-01-12 Not clear
Julia T Brouard, Judith V Schweimer, Rachel Houlton, Katherine E Burnham, Philip Qu\\xc3\\xa9r\\xc3\\xa9e, Trevor Shar. Pharmacological Evidence for 5-HT6 Receptor Modulation of 5-HT Neuron Firing in Vivo. ACS chemical neuroscience vol 6 issue 7 2016 25837696 in summary, the current data show the modulation of 5-ht neuronal firing by the 5-ht6 ligands way-181187 and sb-399885 and are consistent with the presence of 5-ht6 receptor-mediated positive feedback control of 5-ht neurons. 2016-04-19 2022-01-12 Not clear
Nozomi Asaoka, Kazuki Nagayasu, Naoya Nishitani, Mayumi Yamashiro, Hisashi Shirakawa, Takayuki Nakagawa, Shuji Kanek. Olanzapine augments the effect of selective serotonin reuptake inhibitors by suppressing GABAergic inhibition via antagonism of 5-HT\\xe2\\x82\\x86 receptors in the dorsal raphe nucleus. Neuropharmacology vol 95 issue 2016 25863120 here, we report that olanzapine enhances the ssri-induced increase in extracellular serotonin (5-ht) levels and antidepressant-like effects by inhibiting gabaergic neurons through 5-ht6 receptor antagonism in the dorsal raphe nucleus (drn). 2016-03-24 2022-01-12 Not clear
Nozomi Asaoka, Kazuki Nagayasu, Naoya Nishitani, Mayumi Yamashiro, Hisashi Shirakawa, Takayuki Nakagawa, Shuji Kanek. Olanzapine augments the effect of selective serotonin reuptake inhibitors by suppressing GABAergic inhibition via antagonism of 5-HT\\xe2\\x82\\x86 receptors in the dorsal raphe nucleus. Neuropharmacology vol 95 issue 2016 25863120 among many serotonergic agents, the 5-ht6 receptor antagonist sb399885 (1-100 \xce\xbcm) mimicked the effects of olanzapine by enhancing the ssri-induced increase in extracellular 5-ht levels, which was not further augmented by bicuculline or olanzapine. 2016-03-24 2022-01-12 Not clear
D Eskenazi, M Brodsky, J F Neumaie. Deconstructing 5-HT6 receptor effects on striatal circuit function. Neuroscience vol 299 issue 2016 25934037 whereas d1 and d2 receptors and several neuropeptides, including dynorphin and enkephalin, are differentially expressed in these neurons, 5-hydroxytryptamine 6 receptors (5-ht6) are expressed in both pathways. 2016-02-29 2022-01-12 Not clear
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