All Relations between akt1 and sirt1

Publication Sentence Publish Date Extraction Date Species
Jin Dai, Haifeng Wang, Libin Jiang, Fuying Zhang, Jin Lin, Ling Wang, Jun Yang, Xiao Wan. Exploring the therapeutic mechanisms of Sijunzi decoction in the treatment of sarcopenia: Key targets and signaling pathways. Biomedical chromatography : BMC. 2023-08-23. PMID:37609865. sijunzi decoction treats sarcopenia by targeting sirt1, il-6, tnf and akt1, potentially involving foxo and hif-1 signaling pathways. 2023-08-23 2023-09-07 rat
Jin Dai, Haifeng Wang, Libin Jiang, Fuying Zhang, Jin Lin, Ling Wang, Jun Yang, Xiao Wan. Exploring the therapeutic mechanisms of Sijunzi decoction in the treatment of sarcopenia: Key targets and signaling pathways. Biomedical chromatography : BMC. 2023-08-23. PMID:37609865. validation experiments showed that sjzd alleviates sarcopenia by downregulating sirt1, il-6, tnf and akt1. 2023-08-23 2023-09-07 rat
Haiqiong Chen, Miaoqing Liu, Qiyao Li, Pingjiang Zhou, Jie Huang, Qiqi Zhu, Zhongrong Li, Ren-Shan G. Exposure to dipentyl phthalate in utero disrupts the adrenal cortex function of adult male rats by inhibiting SIRT1/PGC-1α and inducing AMPK phosphorylation. Environmental toxicology. 2023-01-30. PMID:36715143. in conclusion, in utero exposure to dpep disrupts adrenocortical function of the adult male offspring by (1) increasing ampk phosphorylation and decreasing akt1 phosphorylation and sirt1 levels, (2) reducing adrenocorticotropic hormone levels, and (3) possibly inducing oxidative stress and apoptosis. 2023-01-30 2023-08-14 rat
Jinling Hou, Shaohui Wang, Yan Chen Shang, Zhao Zhong Chong, Kenneth Maies. Erythropoietin employs cell longevity pathways of SIRT1 to foster endothelial vascular integrity during oxidant stress. Current neurovascular research. vol 8. issue 3. 2011-11-21. PMID:21722091. epo through sirt1 averts apoptosis through activation of protein kinase b (akt1) and the phosphorylation and cytoplasmic retention of the forkhead transcription factor foxo3a. 2011-11-21 2023-08-12 Not clear
Jinling Hou, Zhao Zhong Chong, Yan Chen Shang, Kenneth Maies. Early apoptotic vascular signaling is determined by Sirt1 through nuclear shuttling, forkhead trafficking, bad, and mitochondrial caspase activation. Current neurovascular research. vol 7. issue 2. 2010-08-10. PMID:20370652. the ability of sirt1 to avert apoptosis employs the activation of protein kinase b (akt1), the post-translational phosphorylation of the forkhead member foxo3a, the blocked trafficking of foxo3a to the nucleus, and the inhibition of foxo3a to initiate a "pro-apoptotic" program as shown by complimentary gene knockdown studies of foxo3a. 2010-08-10 2023-08-12 Not clear