| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| Spiro Khoury, Vanessa Soubeyre, St\\xc3\\xa9phanie Cabaret, St\\xc3\\xa9phane Gr\\xc3\\xa9goire, Esther M\\xc3\\xa9zi\\xc3\\xa8re, Elodie Masson, Xavier Grosmaitre, Lionel Bretillon, Olivier Berdeaux, Niyazi Acar, Anne Marie Le Bo. Impact of dietary n-3 polyunsaturated fatty acid intake during the perinatal and post-weaning periods on the phospholipid and ganglioside composition of olfactory tissues. Prostaglandins, leukotrienes, and essential fatty acids vol 191 issue 2023 36870298 |
in this study, we evaluated the impact of feeding mice diets that are either deficient in \xce\xb1-linolenic acid (ala) or supplemented with n-3 long-chain pufas from gestation to adolescence on the phospholipid and ganglioside composition of these tissues. |
2023-03-04 |
2023-03-06 |
mouse |
| Isabel Solares, Daniel Jeric\\xc3\\xb3, Karol M C\\xc3\\xb3rdoba, Montserrat Morales-Conejo, Javier Ena, Rafael Enr\\xc3\\xadquez de Salamanca, Antonio Fontanella. Understanding Carbohydrate Metabolism and Insulin Resistance in Acute Intermittent Porphyria. International journal of molecular sciences vol 24 issue 1 2023 36613492 |
given the increased prevalence of insulin resistance in patients and the large urinary loss of succinyl-coa to produce ala and pbg, we explore the impact of reduced availability of energy metabolites in the severity of aip pathophysiology. |
2023-01-08 |
2023-01-30 |
mouse |
| Mitsuhiro Kamimura, Toshiya Inui, Atsuto Mouri, Hiroaki Todo, Kenji Sugibayashi, Koichiro Asan. A Pilot Study of Transdermal Application of Diphenhydramine to the Nasal Ala in Patients with Allergic Rhinitis and Asthma. The Tokai journal of experimental and clinical medicine vol 47 issue 4 2022 36420548 |
we studied the efficacy, safety, and impact on co-existing asthma symptoms of transdermal delivery of diphenhydramine through the nasal ala. |
2022-11-24 |
2023-01-30 |
Not clear |
| D Z Abdel Hamid, Y A Nienaa, T M Mostaf. Alpha-lipoic acid improved anemia, erythropoietin resistance, maintained glycemic control, and reduced cardiovascular risk in diabetic patients on hemodialysis: a multi-center prospective randomized controlled study. European review for medical and pharmacological sciences vol 26 issue 7 2022 35442486 |
to investigate the impact of alpha-lipoic acid (ala) on inflammation, oxidative stress, anemia, and glycemic parameters and their association with cardiovascular risk in diabetic patients on hemodialysis. |
2022-04-20 |
2023-01-27 |
Not clear |
| Cathriona R Monnard, Abdul G Dullo. Polyunsaturated fatty acids as modulators of fat mass and lean mass in human body composition regulation and cardiometabolic health. Obesity reviews : an official journal of the International Association for the Study of Obesity vol 22 Suppl 2 issue 2021 33471425 |
there is also emerging evidence, which suggests that high intakes of the plant-based essential fatty acids (epufas)-n-6 linoleic acid (la) and n-3 \xce\xb1-linolenic acid (ala)-have a greater impact on body composition (fat mass and lean mass) and on glucose homeostasis than the marine-derived long-chain n-3 pufa-eicosapentaenoic acid (epa) and docosahexaenoic acid (dha). |
2021-10-15 |
2023-01-26 |
human |
| Leslie Cou\\xc3\\xabdelo, Benjamin Buaud, H\\xc3\\xa9l\\xc3\\xa8ne Abrous, Ikram Chamekh-Coelho, Didier Majou, Carole Bou\\xc3\\xa9-Vayss. Effect of increased levels of dietary The British journal of nutrition vol issue 2021 34462019 |
effect of increased levels of dietary we investigated the impact of increased alpha-linolenic acid (ala) dietary levels on its plasma bioavailability and its bioconversion in n-3 long chain poly unsaturated fatty acids during a 60-d kinetics and the oxidative stress potentially associated. |
2021-08-31 |
2023-01-26 |
rat |
| Leslie Cou\\xc3\\xabdelo, Benjamin Buaud, H\\xc3\\xa9l\\xc3\\xa8ne Abrous, Ikram Chamekh-Coelho, Didier Majou, Carole Bou\\xc3\\xa9-Vayss. Effect of increased levels of dietary The British journal of nutrition vol issue 2021 34462019 |
additionally, the improvement of ala bioconversion in epa and dha did not impact the oxidative stress markers and limiting lipid peroxidation. |
2021-08-31 |
2023-01-26 |
rat |
| Nicole R Bonetti, Luca Liberale, Alexander Akhmedov, Lisa Pasterk, Sara Gobbato, Yustina M Puspitasari, Ana Vukolic, Seyed Soheil Saeedi Saravi, Bernd Coester, Carla Horvath, Elena Osto, Fabrizio Montecucco, Thomas F L\\xc3\\xbcscher, J\\xc3\\xbcrg H Beer, Giovanni G Camic. Long-term dietary supplementation with plant-derived omega-3 fatty acid improves outcome in experimental ischemic stroke. Atherosclerosis vol 325 issue 2021 33915355 |
we hereby aimed to investigate the impact of a clinically relevant long-term dietary intervention with ala on stroke outcome. |
2021-06-23 |
2023-01-26 |
Not clear |
| Jolanta Bujok, Dorota Mi\\xc5\\x9bta, Edyta Wincewicz, Bo\\xc5\\xbcena Kr\\xc3\\xb3liczewska, Stanis\\xc5\\x82aw Dzimira, Magdalena \\xc5\\xbbu. Atherosclerosis Development and Aortic Contractility in Hypercholesterolemic Rabbits Supplemented with Two Different Flaxseed Varieties. Foods (Basel, Switzerland) vol 10 issue 3 2021 33806676 |
linola flaxseed with a low ala content more effectively reduced the atherosclerosis progression compared with the w86 flaxseed with a high concentration of stable ala. aorta contractility studies suggested that flaxseed ameliorated an increased contractility in hypercholesterolemia but had little or no impact on no synthesis in the vascular wall. |
2021-04-13 |
2023-01-26 |
Not clear |
| Sugeedha Jeyapal, Suryam Reddy Kona, Surekha Venkata Mullapudi, Uday Kumar Putcha, Puvaneswari Gurumurthy, Ahamed Ibrahi. Substitution of linoleic acid with \\xce\\xb1-linolenic acid or long chain n-3 polyunsaturated fatty acid prevents Western diet induced nonalcoholic steatohepatitis. Scientific reports vol 8 issue 1 2019 30026586 |
this study investigates the impact of substitution of linoleic acid with \xce\xb1-linolenic acid (ala) or long chain (lc) n-3 pufa and hence decreasing n-6:n-3 fatty acid ratio on high fat, high fructose (hfhf) diet induced nonalcoholic steatohepatitis (nash). |
2019-10-17 |
2023-01-26 |
rat |
| Alex Rajna, Heather Gibling, Ousseynou Sarr, Sarthak Matravadia, Graham P Holloway, David M Mutc. Alpha-linolenic acid and linoleic acid differentially regulate the skeletal muscle secretome of obese Zucker rats. Physiological genomics vol 50 issue 8 2019 29727591 |
altogether, the present data indicate that obesity has a greater global impact on skeletal muscle gene expression than either essential pufa; however, la and ala may exert their metabolic benefits in part by regulating the skeletal muscle secretome. |
2019-08-26 |
2023-01-26 |
rat |
| Shweta Modgil, Sridhar Bammidi, Avijit Banik, Vijay Lakshmi Sharma, Akshay Anan. Alpha lipoic acid attenuates the long-term effects of lead exposure in retinal ischemic injury mouse model. Environmental science and pollution research international vol 26 issue 15 2019 30945075 |
histological and molecular analysis revealed that pb-treated mice had greater retinal damage after i/r injury as compared to untreated or ala treated mice, suggesting that ala protects the early-life pb exposure and its consequent impact on later life. |
2019-07-02 |
2023-01-26 |
mouse |
| Carlos Cardoso, Joana Paiva Martinho, Paula A Lopes, Susana Martins, Jorge Correia, Cl\\xc3\\xa1udia Afonso, Francisco J Alarc\\xc3\\xb3n, Mar\\xc3\\xada J Gonz\\xc3\\xa1lez-Fern\\xc3\\xa1ndez, Rui M Pinto, Jos\\xc3\\xa9 A Prates, Narcisa M Bandarra, Jos\\xc3\\xa9 L Guil-Guerrer. Stearidonic acid combined with alpha-linolenic acid improves lipemic and neurological markers in a rat model subject to a hypercaloric diet. Prostaglandins, leukotrienes, and essential fatty acids vol 135 issue 2019 30103925 |
the most positive impact of ala and sda was the beneficial reduction of total lipids (from 395\xe2\x80\xaf\xc2\xb1\xe2\x80\xaf3 to 352-361\xe2\x80\xafmg/dl), vldl-cholesterol (from 21.8\xe2\x80\xaf\xc2\xb1\xe2\x80\xaf0.2 to 14.1-17.8\xe2\x80\xafmg/dl), and triacylglycerols (from 109\xe2\x80\xaf\xc2\xb1\xe2\x80\xaf1 to 71-89\xe2\x80\xafmg/dl) in both lin (diet enriched in linseed oil) and bug (diet enriched in buglossoides oil) groups. |
2019-04-03 |
2023-01-26 |
human |
| Aaron L Morgan, Roger Cason, Christian A El Am. Anthropometrically-Based Surgical Technique for Tessier 3 Cleft Reconstruction. The Journal of craniofacial surgery vol 27 issue 8 2018 28005824 |
the tessier number 3 cleft, the most medial of the oblique clefts, can manifest as clefting of the lip between the canine and lateral incisors, colobomas of the nasal ala and lower eyelid, and inferior displacement of the medial canthus-frequently disrupting the lacrimal system with extreme variability in expressivity (eppley).literature on cleft lip repair is extensive and has evolved to incorporate anthropometric techniques, based on identifiable landmarks and anthropometric measurements that are compared with contralateral unaffected anatomy or population means and tracked over time to assess impact on growth. |
2018-01-18 |
2023-01-26 |
Not clear |
| M Neijat, O Ojekudo, J D Hous. Effect of flaxseed oil and microalgae DHA on the production performance, fatty acids and total lipids of egg yolk and plasma in laying hens. Prostaglandins, leukotrienes, and essential fatty acids vol 115 issue 2017 27914517 |
employing an experimental design consisting of 70 lohmann lsl-classic hens (n=10/treatment) in a 6-week feeding trial, we examined the impact of graded levels of either flaxseed oil (alpha-linolenic acid, ala) or algal dha (preformed docosahexaenoic acid, dha), each supplying 0.20%, 0.40% and 0.60% total omega-3s. |
2017-11-13 |
2023-01-26 |
Not clear |
| Alexandre Pinel, Elodie Pitois, Jean-Paul Rigaudiere, Chrystele Jouve, Sarah De Saint-Vincent, Brigitte Laillet, Christophe Montaurier, Alain Huertas, Beatrice Morio, Frederic Cape. EPA prevents fat mass expansion and metabolic disturbances in mice fed with a Western diet. Journal of lipid research vol 57 issue 8 2017 27307576 |
the impact of alpha linolenic acid (ala), epa, and dha on obesity and metabolic complications was studied in mice fed a high-fat, high-sucrose (hf) diet. |
2017-09-05 |
2023-01-25 |
mouse |
| Antonio Trani, Giuseppe Gambacorta, Tommaso F Gomes, Pasqua Loizzo, Angela Cassone, Michele Facci. Production and characterisation of reduced-fat and PUFA-enriched Burrata cheese. The Journal of dairy research vol 83 issue 2 2017 27210495 |
fortification was easy to perform under a technical point of view, but the negative sensory impact limited fortification at a maximum of 7\xc2\xb70 mg g-1 fat ala and 6\xc2\xb78 g-1 fat cla. |
2017-02-03 |
2023-01-25 |
Not clear |
| Aline Ferain, Chlo\\xc3\\xa9 Bonnineau, Ineke Neefs, Jean Fran\\xc3\\xa7ois Rees, Yvan Larondelle, Karel A C De Schamphelaere, Cathy Debie. The fatty acid profile of rainbow trout liver cells modulates their tolerance to methylmercury and cadmium. Aquatic toxicology (Amsterdam, Netherlands) vol 177 issue 2017 27288598 |
we observed that (i) the phospholipid composition of the rtl-w1 cells was profoundly modulated by changing the pufa content of the growth medium: major modifications were a high incorporation of the supplemented pufa in the cellular phospholipids, the appearance of direct elongation and desaturation metabolites in the cellular phospholipids as well as a change in the gross phospholipid composition (pufa and monounsaturated fatty acid (mufa) levels and n-3/n-6 ratio); (ii) ala, epa and dpa enrichment significantly protected the rtl-w1 cells against both methylmercury and cadmium; (iv) dha enrichment significantly protected the cells against cadmium but not methylmercury; (v) aa and la enrichment had no impact on the cell tolerance to both methylmercury and cadmium; (vi) the abundance of 20:3n-6, a metabolite of the n-6 biotransformation pathway, in phospholipids was negatively correlated to the cell tolerance to both methylmercury and cadmium. |
2017-01-11 |
2023-01-25 |
Not clear |
| Alicia Leikin-Frenkel, Limor Shomonov-Wagner, Ana Juknat, Metsada Pasmanik-Cho. Maternal Diet Enriched with \\xce\\xb1-Linolenic or Saturated Fatty Acids Differentially Regulates Gene Expression in the Liver of Mouse Offspring. Journal of nutrigenetics and nutrigenomics vol 8 issue 4-6 2016 26788914 |
the aim of the present study was to analyze the impact of maternal dietary ala compared to an sfa diet on the liver gene expression in the newborn offspring. |
2016-12-13 |
2023-01-25 |
mouse |
| Steven Tobar, Leticia Tordesillas, M Cecilia Beri. Triclosan promotes epicutaneous sensitization to peanut in mice. Clinical and translational allergy vol 6 issue 2016 27051518 |
we tested the impact of triclosan on epicutaneous sensitization to peanut, as well as the milk allergen \xce\xb1-lactalbumin (ala). |
2016-04-07 |
2023-01-25 |
mouse |