| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yan Hu, Tie-Cheng Guo, Xiang-Yu Zhang, Jun Tian, Yin-Shan L. Paired associative stimulation improves synaptic plasticity and functional outcomes after cerebral ischemia. Neural regeneration research. vol 14. issue 11. 2020-09-30. PMID:31290455. |
we measured mrna and protein expression levels of brain-derived neurotrophic factor and n-methyl-d-aspartate receptor 1 in the hippocampus using a real-time polymerase chain reaction and western blot assay. |
2020-09-30 |
2023-08-13 |
rat |
| Yan Hu, Tie-Cheng Guo, Xiang-Yu Zhang, Jun Tian, Yin-Shan L. Paired associative stimulation improves synaptic plasticity and functional outcomes after cerebral ischemia. Neural regeneration research. vol 14. issue 11. 2020-09-30. PMID:31290455. |
the observed effect may be mediated by increases in the mrna and protein expression of brain-derived neurotrophic factor and n-methyl-d-aspartate receptor 1, and by enhanced synaptic plasticity in the ca1 area of the hippocampus. |
2020-09-30 |
2023-08-13 |
rat |
| Man-Man Zong, Zhi-Qiang Zhou, Mu-Huo Ji, Min Jia, Hui Tang, Jian-Jun Yan. Activation of β2-Adrenoceptor Attenuates Sepsis-Induced Hippocampus-Dependent Cognitive Impairments by Reversing Neuroinflammation and Synaptic Abnormalities. Frontiers in cellular neuroscience. vol 13. 2020-09-30. PMID:31354429. |
the levels of hippocampal β2-ar, proinflammatory cytokines tumor necrosis factor (tnf-α), interleukin-1β (il-1β), il-6, camp-response element binding protein (creb), brain derived neurotrophic factor (bdnf), post-synaptic density protein 95 (psd95), and nmda receptor 2 b subtypes (glun2b) were determined at 6, 12, 24 h and 7 and 16 days after clp. |
2020-09-30 |
2023-08-13 |
mouse |
| Rocío Beatriz Foltran, Karen Melany Stefani, Antonela Bonafina, Agustina Resasco, Silvina Laura Dia. Differential Hippocampal Expression of BDNF Isoforms and Their Receptors Under Diverse Configurations of the Serotonergic System in a Mice Model of Increased Neuronal Survival. Frontiers in cellular neuroscience. vol 13. 2020-09-30. PMID:31555094. |
in particular, the brain-derived neurotrophic factor, bdnf, is highly expressed in the hippocampus (hc) of rodents and participates in the control of neuronal proliferation, and survival in the dentate gyrus (dg). |
2020-09-30 |
2023-08-13 |
mouse |
| Efstathios Garoflos, Theofanis Panagiotaropoulos, Stavroula Pondiki, Antonios Stamatakis, Eleni Philippidis, Fotini Stylianopoulo. Cellular mechanisms underlying the effects of an early experience on cognitive abilities and affective states. Annals of general psychiatry. vol 4. 2020-09-29. PMID:15876359. |
in the present study we investigated the effects of neonatal handling, an animal model of early experience, on spatial learning and memory, on hippocampal glucocorticoid (gr), mineralocorticoid (mr) and type 1a serotonin (5-ht1a) receptors, as well as brain derived neurotrophic factor (bdnf), and on circulating leptin levels, of male rats. |
2020-09-29 |
2023-08-12 |
rat |
| Shahla Shojaei, Mohammad Reza Panjehshahin, Sayed Mohammad Shafiee, Zahra Khoshdel, Mohammad Borji, Ghasem Ghasempour, Ali Akbar Owj. Differential Effects of Resveratrol on the Expression of Brain-Derived Neurotrophic Factor Transcripts and Protein in the Hippocampus of Rat Brain. Iranian journal of medical sciences. vol 42. issue 1. 2020-09-29. PMID:28293048. |
differential effects of resveratrol on the expression of brain-derived neurotrophic factor transcripts and protein in the hippocampus of rat brain. |
2020-09-29 |
2023-08-13 |
rat |
| Najmeh Asrari, Rezvan Yazdian-Robati, Khalil Abnous, BiBi Marjan Razavi, Mrazieh Rashednia, Faezeh Vahdati Hasani, Hossein Hosseinzade. Antidepressant effects of aqueous extract of saffron and its effects on CREB, P-CREB, BDNF, and VGF proteins in rat cerebellum. Journal of pharmacopuncture. vol 21. issue 1. 2020-09-29. PMID:30151303. |
the role of bdnf (brain-derived neurotrophic factor), creb (camp response element binding) and vgf neuropeptide has been proved in antidepressant activity of long term saffron administration in the rat hippocampus. |
2020-09-29 |
2023-08-13 |
rat |
| Lei Gao, Peng Huang, Zhaoyang Dong, Tingting Gao, Shaohui Huang, Chuying Zhou, Yuling Lai, Guanghui Deng, Bin Liu, Ge Wen, Zhiping L. Modified Xiaoyaosan (MXYS) Exerts Anti-depressive Effects by Rectifying the Brain Blood Oxygen Level-Dependent fMRI Signals and Improving Hippocampal Neurogenesis in Mice. Frontiers in pharmacology. vol 9. 2020-09-29. PMID:30323763. |
previous work in our lab has demonstrated that depression induced by chronic stress could generate brain blood oxygen level-dependent (bold) functional magnetic resonance imaging (fmri) signals disorder, accompanied by the impairment of hippocampal neuronal plasticity, decrease of brain-derived neurotrophic factor, and reduction of the number and complexity of adult neurons in the dentate gyrus. |
2020-09-29 |
2023-08-13 |
mouse |
| David Popovic, Andrea Schmitt, Lalit Kaurani, Fanny Senner, Sergi Papiol, Berend Malchow, Andre Fischer, Thomas G Schulze, Nikolaos Koutsouleris, Peter Falka. Childhood Trauma in Schizophrenia: Current Findings and Research Perspectives. Frontiers in neuroscience. vol 13. 2020-09-29. PMID:30983960. |
additive effects between childhood trauma and brain-derived neurotrophic factor methionine carriers on volume loss of the hippocampal subregions cornu ammonis (ca)4/dentate gyrus and ca2/3 have been reported in schizophrenia patients. |
2020-09-29 |
2023-08-13 |
Not clear |
| Charles Brenne. Why Is Mom Stressed: Homeorhesis as the Potential Problem and Nicotinamide Riboside as the Potential Solution. Journal of experimental neuroscience. vol 13. 2020-09-29. PMID:31452603. |
furthermore, by supporting a new mother's apparent higher demand for nad precursors, we increased circulation of prolactin, superinduced mammary biosynthetic programs, increased her time of arched-back nursing, enhanced mammary production of brain-derived neurotrophic factor, promoted postgestational weight loss, advanced the neurobehavioral development of her offspring, and allowed them to mature as stronger and more resilient adults with advantages in hippocampal neurogenesis and body composition. |
2020-09-29 |
2023-08-13 |
mouse |
| Jiang Zhong, Wei X. Characterization of DNA hydroxymethylation in the hypothalamus of elderly mice with post-operative cognitive dysfunction. Experimental and therapeutic medicine. vol 18. issue 5. 2020-09-29. PMID:31641381. |
the results of immunoprecipitation and quantitative pcr revealed that 5hmc modification of the promoters of genes associated with neural protection and development, such as glial cell-derived neurotrophic factor, brain derived neurotrophic factor, glucocorticoid receptor and acyl-coa sythetase short chain family member 2, was reduced in the hippocampus of pocd mice when compared with non-pocd and control mice. |
2020-09-29 |
2023-08-13 |
mouse |
| Tong Wu, Xiao-Yu Sun, Xiu Yang, Le Liu, Kun Tong, Ya Gao, Jing-Ru Hao, Jing Cao, Can Ga. Histone H3K9 Trimethylation Downregulates the Expression of Brain-Derived Neurotrophic Factor in the Dorsal Hippocampus and Impairs Memory Formation During Anaesthesia and Surgery. Frontiers in molecular neuroscience. vol 12. 2020-09-29. PMID:31708739. |
histone h3k9 trimethylation downregulates the expression of brain-derived neurotrophic factor in the dorsal hippocampus and impairs memory formation during anaesthesia and surgery. |
2020-09-29 |
2023-08-13 |
Not clear |
| Anderson Camargo, Ana Lúcia S Rodrigue. Novel Targets for Fast Antidepressant Responses: Possible Role of Endogenous Neuromodulators. Chronic stress (Thousand Oaks, Calif.). vol 3. 2020-09-28. PMID:32440595. |
the possibility that these neuromodulators and ketamine have common neurobiological mechanisms, mainly the ability to activate mechanistic target of rapamycin and brain-derived neurotrophic factor signaling, and synthesis of synaptic proteins in the prefrontal cortex and/or hippocampus is presented and discussed. |
2020-09-28 |
2023-08-13 |
Not clear |
| Mijail Rojas-Carvajal, Andrey Sequeira-Cordero, Juan C Brene. Neurobehavioral Effects of Restricted and Unpredictable Environmental Enrichment in Rats. Frontiers in pharmacology. vol 11. 2020-09-28. PMID:32477137. |
in the dorsal striatum and hippocampus, ree upregulated the expression of the brain-derived neurotrophic factor, its tropomyosin kinase b receptor, and the dna methyltransferase 3a. |
2020-09-28 |
2023-08-13 |
rat |
| Tae-Won Kim, Kyung-Wan Baek, Hak Sun Yu, Il-Gyu Ko, Lakkyong Hwang, Jung-Jun Par. High-intensity exercise improves cognitive function and hippocampal brain-derived neurotrophic factor expression in obese mice maintained on high-fat diet. Journal of exercise rehabilitation. vol 16. issue 2. 2020-09-28. PMID:32509696. |
high-intensity exercise improves cognitive function and hippocampal brain-derived neurotrophic factor expression in obese mice maintained on high-fat diet. |
2020-09-28 |
2023-08-13 |
mouse |
| Jianxin Li, Ling Chen, Gaowen Li, Xiaojuan Chen, Sisi Hu, Liang Zheng, Victor Luria, Jinpeng Lv, Yindi Sun, Ying Xu, Yingcong Y. Sub-Acute Treatment of Curcumin Derivative J147 Ameliorates Depression-Like Behavior Through 5-HT Frontiers in neuroscience. vol 14. 2020-09-28. PMID:32733195. |
our previous study suggested that acute treatment with a novel curcumin derivative j147 exhibited antidepressant-like effects by increasing brain derived neurotrophic factor (bdnf) level in the hippocampus of mice. |
2020-09-28 |
2023-08-13 |
mouse |
| Ismail O Ishola, Mmesomachukwu O Osele, Micah C Chijioke, Olufunmilayo O Adeyem. Isorhamnetin enhanced cortico-hippocampal learning and memory capability in mice with scopolamine-induced amnesia: Role of antioxidant defense, cholinergic and BDNF signaling. Brain research. vol 1712. 2020-09-11. PMID:30772273. |
one hour after probe test (mwm task) on day 7, the brains were isolated to assay for oxidative stress, cholinesterase activity and brain derived neurotrophic factor (bdnf) levels in the prefrontal cortex (pfc) and hippocampus (hippo). |
2020-09-11 |
2023-08-13 |
mouse |
| Wiebke Theilmann, Marko Rosenholm, Philip Hampel, Wolfgang Löscher, Tomi Rantamäk. Lack of antidepressant effects of burst-suppressing isoflurane anesthesia in adult male Wistar outbred rats subjected to chronic mild stress. PloS one. vol 15. issue 6. 2020-09-07. PMID:32579566. |
tissue samples from the medial prefrontal cortex and hippocampus were collected, and levels of bdnf (brain-derived neurotrophic factor) protein were assessed. |
2020-09-07 |
2023-08-13 |
rat |
| Jing Nie, Sheng-Yu Zhang, Lin Sun, Qi Qiu, Yuan Fang, Xiang Liu, Xia L. [Correlation between Depressive Behavior and Expressions of S100β and Brain-derived Neurotrophic Factor in Hippocampus and Frontal Cortex of Rats]. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae. vol 42. issue 2. 2020-08-18. PMID:32385027. |
[correlation between depressive behavior and expressions of s100β and brain-derived neurotrophic factor in hippocampus and frontal cortex of rats]. |
2020-08-18 |
2023-08-13 |
rat |
| Gabriela Pandini Silote, Ariandra Sartim, Amanda Sales, Amanda Eskelund, F S Guimarães, Gregers Wegener, Samia Joc. Emerging evidence for the antidepressant effect of cannabidiol and the underlying molecular mechanisms. Journal of chemical neuroanatomy. vol 98. 2020-08-17. PMID:31039391. |
moreover, cbd induces cellular and molecular changes in brain regions related to depression neurobiology, such as increased brain derived neurotrophic factor (bdnf) levels and synaptogenesis in the medial prefrontal cortex, as well as it increases neurogenesis in the hippocampus. |
2020-08-17 |
2023-08-13 |
Not clear |