| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alberto S de Sá, Carlos Campos, Nuno B F Rocha, Ti-Fei Yuan, Flávia Paes, Oscar Arias-Carrión, Mauro G Carta, Antonio E Nardi, Elie Cheniaux, Sergio Machad. Neurobiology of Bipolar Disorder: Abnormalities on Cognitive and Cortical Functioning and Biomarker Levels. CNS & neurological disorders drug targets. vol 15. issue 6. 2017-10-03. PMID:26996165. |
these deficits are assigned to functional, structural and metabolic changes, particularly in the pre-frontal cortex region, hippocampus and amygdala, along with the connections between them, as well as decreased baseline brain-derived neurotrophic factor levels or imbalance between pro- and anti-inflammatory cytokines, implying a lower physical ability to reestablish from a stressful stimulus. |
2017-10-03 |
2023-08-13 |
human |
| Rebeca Vargas Antunes Schunck, Isabel Cristina Macedo, Gabriela Laste, Andressa de Souza, Marina Tuerlinckx Costa Valle, Janaína L O Salomón, Ellen Almeida Nunes, Andreia Cristina Wildner Campos, Simone Cristina Baggio Gnoatto, Ana Maria Bergold, Eduardo L Konrath, Eliane Dallegrave, Marcelo Dutra Arbo, Iraci L S Torres, Mirna Bainy Lea. Standardized Passiflora incarnata L. Extract Reverts the Analgesia Induced by Alcohol Withdrawal in Rats. Phytotherapy research : PTR. vol 31. issue 8. 2017-10-03. PMID:28568647. |
in addition, brain-derived neurotrophic factor and interleukin-10 levels were evaluated in prefrontal cortex, brainstem, and hippocampus. |
2017-10-03 |
2023-08-13 |
rat |
| Yi Fan, Hui Kong, Xinhai Ye, Jianhua Ding, Gang H. ATP-sensitive potassium channels: uncovering novel targets for treating depression. Brain structure & function. vol 221. issue 6. 2017-09-28. PMID:26289962. |
next, using kir6.2 knockout (kir6.2(-/-)) mice, we presented that kir6.2 deficiency resulted in antidepressant-like behaviors under non-stress conditions, but aggravated depressive behaviors accompanied by the loss of ca3 neuron and the reduction of brain-derived neurotrophic factor in hippocampus under chronic stress. |
2017-09-28 |
2023-08-13 |
mouse |
| Alessia Bachis, Erin Wenzel, Allyssia Boelk, Jodi Becker, Italo Mocchett. The neurotrophin receptor p75 mediates gp120-induced loss of synaptic spines in aging mice. Neurobiology of aging. vol 46. 2017-09-28. PMID:27498053. |
old (∼10 months) gp120tg mice exhibited an increase in proneurotrophin brain-derived neurotrophic factor levels in the hippocampus as well as a decrease in the number of dendritic spines when compared to age-matched wild type. |
2017-09-28 |
2023-08-13 |
mouse |
| Gerd Wagner, Marco Herbsleb, Feliberto de la Cruz, Andy Schumann, Stefanie Köhler, Christian Puta, Holger W Gabriel, Jürgen R Reichenbach, Karl-Jürgen Bä. Changes in fMRI activation in anterior hippocampus and motor cortex during memory retrieval after an intense exercise intervention. Biological psychology. vol 124. 2017-09-20. PMID:28119067. |
we further aimed to relate putative changes in hippocampal activation to postulated changes in the exercised-induced brain derived neurotrophic factor (bdnf). |
2017-09-20 |
2023-08-13 |
human |
| A R Graves, S J Moore, N Spruston, A K Tryba, C C Kaczorowsk. Brain-derived neurotrophic factor differentially modulates excitability of two classes of hippocampal output neurons. Journal of neurophysiology. vol 116. issue 2. 2017-09-07. PMID:27146982. |
brain-derived neurotrophic factor differentially modulates excitability of two classes of hippocampal output neurons. |
2017-09-07 |
2023-08-13 |
Not clear |
| Marco Aurélio Mori, Erika Meyer, Ligia Mendes Soares, Humberto Milani, Francisco Silveira Guimarães, Rúbia Maria Weffort de Oliveir. Cannabidiol reduces neuroinflammation and promotes neuroplasticity and functional recovery after brain ischemia. Progress in neuro-psychopharmacology & biological psychiatry. vol 75. 2017-09-07. PMID:27889412. |
in addition, ischemic mice treated with cbd exhibited an increase in the hippocampal brain derived neurotrophic factor (bdnf) protein levels. |
2017-09-07 |
2023-08-13 |
mouse |
| Yosuke Takeda, Hiroshi Oue, Shinsuke Okada, Akira Kawano, Katsunori Koretake, Makoto Michikawa, Yasumasa Akagawa, Kazuhiro Tsug. Molar loss and powder diet leads to memory deficit and modifies the mRNA expression of brain-derived neurotrophic factor in the hippocampus of adult mice. BMC neuroscience. vol 17. issue 1. 2017-08-23. PMID:27919226. |
molar loss and powder diet leads to memory deficit and modifies the mrna expression of brain-derived neurotrophic factor in the hippocampus of adult mice. |
2017-08-23 |
2023-08-13 |
mouse |
| Jiah Pearson-Leary, Ewan C McNa. Novel Roles for the Insulin-Regulated Glucose Transporter-4 in Hippocampally Dependent Memory. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 47. 2017-08-18. PMID:27881773. |
these effects were accompanied by increased expression of hippocampal ampa glur1 subunits and the neuronal glut3, but decreased expression of hippocampal brain-derived neurotrophic factor, consistent with impaired ability to form long-term memories. |
2017-08-18 |
2023-08-13 |
rat |
| N N Kudryavtseva, D A Smagin, I L Kovalenko, A G Galyamina, G B Vishnivetskaya, V N Babenko, Yu L Orlo. [Serotonergic genes in the development of anxiety/depression-like state and pathology of aggressive behavior in male mice: RNA-seq data]. Molekuliarnaia biologiia. vol 51. issue 2. 2017-08-14. PMID:28537235. |
using the data of whole transcriptome analysis (rna-seq), the changes in the expression of serotonergic genes involved in the synthesis, inactivation, and reception of serotonin, as well as of the creb1 (transcription factor) gene and the bdnf (brain-derived neurotrophic factor) gene were detected in the striatum (str), ventral tegmental area (vta), midbrain raphe nuclei (mrn), hypothalamus (hyp), and hippocampus (hip) of defeated and aggressive male mice. |
2017-08-14 |
2023-08-13 |
mouse |
| Johanna A Gutiérrez-Vargas, Herman Moreno, Gloria P Cardona-Góme. Targeting CDK5 post-stroke provides long-term neuroprotection and rescues synaptic plasticity. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 37. issue 6. 2017-08-11. PMID:27486045. |
additionally, cyclin-dependent kinase 5 silencing increased the expression of brain-derived neurotrophic factor in the hippocampus. |
2017-08-11 |
2023-08-13 |
rat |
| Rahul Agrawal, Emily Noble, Laurent Vergnes, Zhe Ying, Karen Reue, Fernando Gomez-Pinill. Dietary fructose aggravates the pathobiology of traumatic brain injury by influencing energy homeostasis and plasticity. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 36. issue 5. 2017-07-31. PMID:26661172. |
here we report that fructose consumption disrupts hippocampal energy homeostasis as evidenced by a decline in functional mitochondria bioenergetics (oxygen consumption rate and cytochrome c oxidase activity) and an aggravation of the effects of traumatic brain injury on molecular systems engaged in cell energy homeostasis (sirtuin 1, peroxisome proliferator-activated receptor gamma coactivator-1alpha) and synaptic plasticity (brain-derived neurotrophic factor, tropomyosin receptor kinase b, cyclic adenosine monophosphate response element binding, synaptophysin signaling). |
2017-07-31 |
2023-08-13 |
Not clear |
| Leonardo Ortiz-López, Nelly Maritza Vega-Rivera, Harish Babu, Gerardo Bernabé Ramírez-Rodrígue. Brain-Derived Neurotrophic Factor Induces Cell Survival and the Migration of Murine Adult Hippocampal Precursor Cells During Differentiation In Vitro. Neurotoxicity research. vol 31. issue 1. 2017-07-28. PMID:27663583. |
brain-derived neurotrophic factor induces cell survival and the migration of murine adult hippocampal precursor cells during differentiation in vitro. |
2017-07-28 |
2023-08-13 |
Not clear |
| Burak Yulug, Lütfü Hanoglu, Ahmet M Tavli, Nesrin H Yılmaz, Ertugrul Kılı. The Brain Protective Effect of rTMS (Repetitive Transcranial Magnetic Stimulation) in Depression: A Mini-Review in Animal Studies. Medicinal chemistry (Shariqah (United Arab Emirates)). vol 12. issue 6. 2017-07-04. PMID:26434798. |
we have shown that rtms may exert significant neuroprotective effect through acting on the oxidative injury, stress hormones, dopamine and serotonin levels, brain derived neurotrophic factor expression, neuroinflamation and hippocampal cell proliferation. |
2017-07-04 |
2023-08-13 |
human |
| Siying Xiang, Fufeng Liu, Jiajia Lin, Huixin Chen, Chunhui Huang, Liping Chen, Yiying Zhou, Luying Ye, Ke Zhang, Jiukai Jin, Jiacheng Zhen, Chuang Wang, Shan He, Qinwen Wang, Wei Cui, Jinrong Zhan. Fucoxanthin Inhibits β-Amyloid Assembly and Attenuates β-Amyloid Oligomer-Induced Cognitive Impairments. Journal of agricultural and food chemistry. vol 65. issue 20. 2017-06-22. PMID:28478680. |
in addition, fucoxanthin significantly inhibited oxidative stress, enhanced the expression of brain-derived neurotrophic factor, and increased chat-positive regions in the hippocampus of mice. |
2017-06-22 |
2023-08-13 |
mouse |
| Thomas Demuyser, Eduard Bentea, Lauren Deneyer, Giulia Albertini, Ann Massie, Ilse Smolder. Disruption of the HPA-axis through corticosterone-release pellets induces robust depressive-like behavior and reduced BDNF levels in mice. Neuroscience letters. vol 626. 2017-06-19. PMID:27208833. |
we show that three weeks of corticosterone pellet exposure robustly induces depressive-like but not anxiety-like behavior in mice, accompanied by a significant decrease in hippocampal brain-derived neurotrophic factor levels, at five weeks after the start of treatment. |
2017-06-19 |
2023-08-13 |
mouse |
| Lingpeng Zhu, Chen Nang, Fen Luo, Hong Pan, Kai Zhang, Jingyan Liu, Rui Zhou, Jin Gao, Xiayun Chang, He He, Yue Qiu, Jinglei Wang, Hongyan Long, Yu Liu, Tianhua Ya. Esculetin attenuates lipopolysaccharide (LPS)-induced neuroinflammatory processes and depressive-like behavior in mice. Physiology & behavior. vol 163. 2017-06-16. PMID:27133730. |
in addition, neuroprotection of esculetin was attributed to the upregulations of brain derived neurotrophic factor (bdnf) and phosphorylated tyrosine kinase b (p-trkb) protein expression in hippocampus. |
2017-06-16 |
2023-08-13 |
mouse |
| Hyun-Ja Jeong, Shi-Young Yang, Hee-Yun Kim, Na-Rae Kim, Jae-Bum Jang, Hyung-Min Ki. Chelidonic acid evokes antidepressant-like effect through the up-regulation of BDNF in forced swimming test. Experimental biology and medicine (Maywood, N.J.). vol 241. issue 14. 2017-06-14. PMID:27037280. |
brain-derived neurotrophic factor expression and extracellular signal-regulated protein kinase phosphorylation in the hippocampus were up-regulated by the administration of chelidonic acid. |
2017-06-14 |
2023-08-13 |
mouse |
| Wen-Guang Xia, Chan-Juan Zheng, Xuan Zhang, Juan Wan. Effects of "nourishing liver and kidney" acupuncture therapy on expression of brain derived neurotrophic factor and synaptophysin after cerebral ischemia reperfusion in rats. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 37. issue 2. 2017-06-13. PMID:28397041. |
the aim of the present study was to investigate the effect of "nourishing liver and kidney" acupuncture therapy on motor and cognitive deficits, and the underlying mechanism following cerebral ischemia-reperfusion (i/r) via increasing the expression of brain derived neurotrophic factor (bdnf) and synaptophysin (syn) in the hippocampus. |
2017-06-13 |
2023-08-13 |
rat |
| Shingo Enomoto, Kunio Shimizu, Masashi Nibuya, Hiroyuki Toda, Aihide Yoshino, Eiji Suzuki, Takashi Kondo, Hiroshi Fukud. Increased expression of endocytosis-Related proteins in rat hippocampus following 10-day electroconvulsive seizure treatment. Neuroscience letters. vol 624. 2017-06-06. PMID:27177725. |
one is the alteration of central neurotransmitter receptor densities and the other is the expressional upregulation of brain derived neurotrophic factor in various brain regions with enhanced hippocampal neurogenesis and mossy fiber sprouting. |
2017-06-06 |
2023-08-13 |
rat |