| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jiaqing Yang, Shilei Song, Jian Li, Tao Lian. Neuroprotective effect of curcumin on hippocampal injury in 6-OHDA-induced Parkinson's disease rat. Pathology, research and practice. vol 210. issue 6. 2014-12-12. PMID:24642369. |
furthermore, curcumin obviously up-regulated hippocampal brain derived neurotrophic factor (bdnf), trkb, phosphatidylinositide 3-kinases (pi3k) protein expressions, respectively as shown in western blot analysis. |
2014-12-12 |
2023-08-12 |
rat |
| Katherine M Baumgarner, Sharay Setti, Carolyn Diaz, Alyssa Littlefield, Amanda Jones, Rachel A Kohma. Diet-induced obesity attenuates cytokine production following an immune challenge. Behavioural brain research. vol 267. 2014-12-11. PMID:24657736. |
dio also reduced hippocampal expression of brain-derived neurotrophic factor and the pre-synaptic marker synaptophysin. |
2014-12-11 |
2023-08-12 |
mouse |
| Darcy Litteljohn, Eric Nelson, Shawn Hayle. IFN-γ differentially modulates memory-related processes under basal and chronic stressor conditions. Frontiers in cellular neuroscience. vol 8. 2014-12-05. PMID:25477784. |
however, contrary to our expectations, neither ifn-γ deletion nor chronic stressor exposure significantly affected nucleus accumbens dopaminergic neurotransmission or hippocampal brain-derived neurotrophic factor protein expression. |
2014-12-05 |
2023-08-13 |
mouse |
| J M Malheiros, M Lima, R D T Avanzi, S Gomes da Silva, D Suchecki, R Guinsburg, L Covola. Repetitive noxious neonatal stimuli increases dentate gyrus cell proliferation and hippocampal brain-derived neurotrophic factor levels. Hippocampus. vol 24. issue 4. 2014-12-03. PMID:24339278. |
repetitive noxious neonatal stimuli increases dentate gyrus cell proliferation and hippocampal brain-derived neurotrophic factor levels. |
2014-12-03 |
2023-08-12 |
rat |
| Gisele Pereira Dias, Mário Cesar do Nascimento Bevilaqua, Anna Claudia Domingos Silveira da Luz, Renata Lopes Fleming, Lítia Alves de Carvalho, Graham Cocks, Danielle Beckman, Lucas Costa Hosken, William de Sant'Anna Machado, Ana Carolina Corrêa-e-Castro, Felippe Mousovich-Neto, Vítor de Castro Gomes, Gilmara de Nazareth Tavares Bastos, Regina Célia Cussa Kubrusly, Vânia Maria Corrêa da Costa, Deepak Srivastava, Jesus Landeira-Fernandez, Antonio Egidio Nardi, Sandrine Thuret, Patricia Franca Gardin. Hippocampal biomarkers of fear memory in an animal model of generalized anxiety disorder. Behavioural brain research. vol 263. 2014-12-03. PMID:24462725. |
serum corticosterone levels, immunofluorescence for glucocorticoid receptors (gr) in the dentate gyrus (dg), and western blotting for hippocampal brain derived neurotrophic factor (bdnf) were performed. |
2014-12-03 |
2023-08-12 |
rat |
| Irit Gil-Ad, Moshe Portnoy, Igor Tarasenko, Miri Bidder, Maria Kramer, Michal Taler, Abraham Weizma. A novel analog of olanzapine linked to sarcosinyl moiety (PGW5) demonstrates high efficacy and good safety profile in mouse models of schizophrenia. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 24. issue 3. 2014-11-25. PMID:24389121. |
moreover, pgw5, but not olanzapine, attenuated phencyclidine (pcp)-induced deficits of social preference in mice and promoted the expression of brain derived neurotrophic factor (bdnf) in the hippocampus and the frontal cortex and glutamic acid decarboxylase (gad67) in the hippocampus. |
2014-11-25 |
2023-08-12 |
mouse |
| Jesper Krogh, Egill Rostrup, Carsten Thomsen, Betina Elfving, Poul Videbech, Merete Nordentof. The effect of exercise on hippocampal volume and neurotrophines in patients with major depression--a randomized clinical trial. Journal of affective disorders. vol 165. 2014-11-24. PMID:24882173. |
the effect of exercise on hippocampal volume is potentially mediated by brain derived neurotrophic factor (bdnf), vascular endothelial growth factor (vegf), and insulin like growth factor 1 (igf-1). |
2014-11-24 |
2023-08-13 |
Not clear |
| Ahmed M Hassan, Piyush Jain, Florian Reichmann, Raphaela Mayerhofer, Aitak Farzi, Rufina Schuligoi, Peter Holze. Repeated predictable stress causes resilience against colitis-induced behavioral changes in mice. Frontiers in behavioral neuroscience. vol 8. 2014-11-21. PMID:25414650. |
dss-induced colitis was associated with an increase in circulating neuropeptide y (npy), a rise in the hypothalamic expression of cyclooxygenase-2 mrna and a decrease in the hippocampal expression of npy mrna, brain-derived neurotrophic factor mrna and mineralocorticoid receptor mrna. |
2014-11-21 |
2023-08-13 |
mouse |
| H F Sakr, K I Khalil, A M Hussein, M S A Zaki, R A Eid, M Alkhatee. Effect of dehydroepiandrosterone (DHEA) on memory and brain derived neurotrophic factor (BDNF) in a rat model of vascular dementia. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 65. issue 1. 2014-11-13. PMID:24622829. |
furthermore, the expression of brain derived neurotrophic factor (bdnf) in the hippocampus was determined. |
2014-11-13 |
2023-08-12 |
rat |
| Rosalia Crupi, Irene Paterniti, Akbar Ahmad, Michela Campolo, Emanuela Esposito, Salvatore Cuzzocre. Effects of palmitoylethanolamide and luteolin in an animal model of anxiety/depression. CNS & neurological disorders drug targets. vol 12. issue 7. 2014-11-12. PMID:23844686. |
adult hippocampal neurogenesis and neuroplasticity were evaluated by immunohistochemical techniques; brain-derived neurotrophic factor and apoptotic protein (bax and bcl2) expression were studied by immunostaining and western blot analysis. |
2014-11-12 |
2023-08-12 |
mouse |
| Dexiang Liu, Kai Xie, Xudong Yang, Jianhua Gu, Li Ge, Xueer Wang, Zhen Wan. Resveratrol reverses the effects of chronic unpredictable mild stress on behavior, serum corticosterone levels and BDNF expression in rats. Behavioural brain research. vol 264. 2014-11-05. PMID:24503118. |
the present study attempts to explore the mechanisms underlying the antidepressant-like action of resveratrol by measuring serum corticosterone levels and the content of brain derived neurotrophic factor (bdnf) in the hippocampus and amygdala of rats exposed to the chronic unpredictable mild stress (cums). |
2014-11-05 |
2023-08-12 |
rat |
| Hui Yao, Li-Jia Gu, Jian-You Gu. [Study on effect of astragali radix polysaccharides in improving learning and memory functions in aged rats and its mechanism]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 39. issue 11. 2014-10-28. PMID:25272845. |
the western-blot method was used to observe the levels of relevant neural plasticity protein n-methyl-d-aspartate receptor (nmda receptor) in hippocampus, calcium/calmodulin dependent protein kinase ii (camk ii), protein kinase (pka), the phosphorylation level of camp response element binding protein (creb) and the protein expression of brain derived neurotrophic factor(bdnf). |
2014-10-28 |
2023-08-13 |
rat |
| Zhaohui Zhang, Pengge Fei, Junlin Mu, Wenqiang Li, Jinggui Son. Hippocampal expression of aryl hydrocarbon receptor nuclear translocator 2 and neuronal PAS domain protein 4 in a rat model of depression. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 35. issue 2. 2014-10-21. PMID:23861074. |
the transcription factors aryl hydrocarbon receptor nuclear translocator 2 (arnt2) and neuronal pas domain protein 4 (npas4) may influence emotion and cognitive function by regulating brain-derived neurotrophic factor expression in the hippocampus. |
2014-10-21 |
2023-08-12 |
rat |
| Daniela Puzzo, Carla Loreto, Salvatore Giunta, Giuseppe Musumeci, Giuseppina Frasca, Maria Vittoria Podda, Ottavio Arancio, Agostino Palmer. Effect of phosphodiesterase-5 inhibition on apoptosis and beta amyloid load in aged mice. Neurobiology of aging. vol 35. issue 3. 2014-09-29. PMID:24112792. |
we demonstrated that chronic intraperitoneal injection of sildenafil (3 mg/kg for 3 weeks) decreased terminal deoxyuridine triphosphate nick end labeling-positive cells in the ca1 hippocampal area of 26-30-month-old mice, downregulating the proapoptotic proteins, caspase-3 and b-cell lymphoma 2-associated x, and increasing antiapoptotic molecules such as b-cell lymphoma protein-2 and brain-derived neurotrophic factor. |
2014-09-29 |
2023-08-12 |
mouse |
| Yi Shu, Hong Zhang, Tao Kang, Jun-jian Zhang, Ying Yang, Hui Liu, Lei Zhan. PI3K/Akt signal pathway involved in the cognitive impairment caused by chronic cerebral hypoperfusion in rats. PloS one. vol 8. issue 12. 2014-09-19. PMID:24339978. |
in previous studies we found that learning capacity and memory were gradually impaired with cch, which altered the expression of synaptophysin, microtubule associated protein-2, growth associated protein-43, brain-derived neurotrophic factor, nerve growth factor, n-methyl-d-aspartate receptor subunit 1, camp response element-binding protein and tau hyperphosphorylation in the hippocampus. |
2014-09-19 |
2023-08-12 |
rat |
| Zeeba D Kabir, Aaron C Katzman, Barry E Kosofsk. Molecular mechanisms mediating a deficit in recall of fear extinction in adult mice exposed to cocaine in utero. PloS one. vol 8. issue 12. 2014-09-16. PMID:24358339. |
while we observed no change in the constitutive expression of brain derived neurotrophic factor (bdnf) protein and mrna in the mpfc and hippocampus of adult pcoc mice, we observed blunted bdnf signaling in the mpfc of adult pcoc mice after fear extinction compared to the control animals. |
2014-09-16 |
2023-08-12 |
mouse |
| Joan M Jasien, Caitlin M Daimon, Rui Wang, Bruce K Shapiro, Bronwen Martin, Stuart Maudsle. The effects of aging on the BTBR mouse model of autism spectrum disorder. Frontiers in aging neuroscience. vol 6. 2014-09-16. PMID:25225482. |
unbiased proteomic analysis of hippocampal and cortical tissue of btbr mice compared to age-matched wild-type controls revealed a significant decrease in brain derived neurotrophic factor and significant increases in multiple synaptic markers (spinophilin, synapsin i, psd 95, neun), as well as distinct changes in functional pathways related to these proteins, including "neural synaptic plasticity regulation" and "neurotransmitter secretion regulation." |
2014-09-16 |
2023-08-13 |
mouse |
| Sung Jin Kwon, Jeongsook Park, So Yun Park, Kwang Seop Song, Sun Tae Jung, So Bong Jung, Ik Ryeul Park, Wan Sung Choi, Sun Ok Kwo. Low-intensity treadmill exercise and/or bright light promote neurogenesis in adult rat brain. Neural regeneration research. vol 8. issue 10. 2014-09-10. PMID:25206384. |
the purpose of this study was to investigate the effects of low-intensity exercise and bright light exposure on neurogenesis and brain-derived neurotrophic factor expression in adult rat hippocampus. |
2014-09-10 |
2023-08-13 |
rat |
| Sung Jin Kwon, Jeongsook Park, So Yun Park, Kwang Seop Song, Sun Tae Jung, So Bong Jung, Ik Ryeul Park, Wan Sung Choi, Sun Ok Kwo. Low-intensity treadmill exercise and/or bright light promote neurogenesis in adult rat brain. Neural regeneration research. vol 8. issue 10. 2014-09-10. PMID:25206384. |
moreover, the expression level of brain-derived neurotrophic factor in the rat hippocampal dentate gyrus was significantly higher in the exercise group and light group than that in the control group. |
2014-09-10 |
2023-08-13 |
rat |
| Lina Zhang, Weiwei Dai, Xueli Zhang, Zhangbin Gong, Guoqin Ji. Mannotriose regulates learning and memory signal transduction in the hippocampus. Neural regeneration research. vol 8. issue 32. 2014-09-10. PMID:25206622. |
thiazolyl blue tetrazolium bromide assay and western blot analysis showed that hippocampal neuron survival rates and protein levels of glucocorti-coid receptor, serum and glucocorticoid-regulated protein kinase, and brain-derived neurotrophic factor were all dramatically decreased after high-concentration corticosterone-induced injury. |
2014-09-10 |
2023-08-13 |
Not clear |