All Relations between brain derived neurotrophic factor and prefrontal cortex

Reference Sentence Publish Date Extraction Date Species
Satoshi Deyama, Katsuyuki Kaned. Role of neurotrophic and growth factors in the rapid and sustained antidepressant actions of ketamine. Neuropharmacology vol 224 issue 2022 36403852 the neurotrophic hypothesis of depression proposes that reduced levels of brain-derived neurotrophic factor (bdnf) and vascular endothelial growth factor (vegf) contribute to neuronal atrophy or loss in the prefrontal cortex (pfc) and hippocampus and impaired hippocampal adult neurogenesis, which are associated with depressive symptoms. 2022-11-22 2022-11-28 Not clear
Ana Paula Farias Waltrick, Ana Carolina Felipe da Silva, Bianca Andretto de Mattos, Yane Costa Chaves, R\\xc3\\xbabia Maria Weffort de Oliveira, Jos Prickaerts, Jana\\xc3\\xadna Menezes Zanovel. Long-term treatment with roflumilast improves learning of fear extinction memory and anxiety-like response in a type-1 diabetes mellitus animal model. Behavioural brain research vol issue 2022 36400237 in addition, there was an increase in the product of the creb signaling pathway, the pro brain-derived neurotrophic factor, in the hip and pfc of these animals. 2022-11-18 2022-11-21 Not clear
Francisco de Borja Belloch, Mar\\xc3\\xada Cort\\xc3\\xa9s-Erice, Etienne Herzog, Xiao Min Zhang, Teresa D\\xc3\\xadaz-Perdigon, Elena Puerta, Rosa M Torder. Fast antidepressant action of ketamine in mouse models requires normal VGLUT1 levels from prefrontal cortex neurons. Progress in neuro-psychopharmacology & biological psychiatry vol issue 2022 36209771 pre-clinical studies suggest that de novo synthesis of the brain-derived neurotrophic factor (bdnf) in the pfc might be involved in the rapid antidepressant action of ketamine. 2022-10-09 2022-10-25 Not clear
Faezeh Kazemi, Shirin Babri, Parisa Keyhanmehr, Mahsa Farid-Habibi, Sepehr Nayebi Rad, Fereshteh Farajdokh. Maternal vitamin D supplementation and treadmill exercise attenuated vitamin D deficiency-induced anxiety-and depressive-like behaviors in adult male offspring rats. Nutritional neuroscience vol issue 2022 35470763 this study examined the effect of maternal vitamin d dietary manipulations and treadmill exercise on anxiety-and depressive-related behaviors, pro-inflammatory cytokines, and prefrontal cortex (pfc) protein levels of brain-derived neurotrophic factor (bdnf) and vitamin d receptor (vdr) in adult male offspring born to vitamin d-deficient diet (vdd)-fed dams. 2022-04-26 2022-04-30 Not clear
Zofia Rog\\xc3\\xb3\\xc5\\xbc, Kinga Kami\\xc5\\x84ska, Marta Anna Lech, El\\xc5\\xbcbieta Lorenc-Koc. N-Acetylcysteine and Aripiprazole Improve Social Behavior and Cognition and Modulate Brain BDNF Levels in a Rat Model of Schizophrenia. International journal of molecular sciences vol 23 issue 4 2022 35216241 the aim of our study was to compare the efficacy of chronic administration of the atypical antipsychotic drug aripiprazole (7-{4-[4-(2,3-dichlorophenyl)-1-piperazinyl] butoxy}-3,4-dihydro-2(1h)-quinolinone; ari) and the well-known antioxidant n-acetylcysteine (nac) both in alleviating schizophrenia-like social and cognitive deficits and in reducing the decreases in the levels of the brain-derived neurotrophic factor (bdnf) in the prefrontal cortex (pfc) and hippocampus (hip) of adult sprague-dawley rats, that have been induced by chronic administration of the model compound l-buthionine-(s, r)-sulfoximine (bso) during the early postnatal development (p5-p16). 2022-03-18 2022-02-28 Not clear
Zofia Rog\\xc3\\xb3\\xc5\\xbc, Kinga Kami\\xc5\\x84ska, Marta Anna Lech, El\\xc5\\xbcbieta Lorenc-Koc. N-Acetylcysteine and Aripiprazole Improve Social Behavior and Cognition and Modulate Brain BDNF Levels in a Rat Model of Schizophrenia. International journal of molecular sciences vol 23 issue 4 2022 35216241 the aim of our study was to compare the efficacy of chronic administration of the atypical antipsychotic drug aripiprazole (7-{4-[4-(2,3-dichlorophenyl)-1-piperazinyl] butoxy}-3,4-dihydro-2(1h)-quinolinone; ari) and the well-known antioxidant n-acetylcysteine (nac) both in alleviating schizophrenia-like social and cognitive deficits and in reducing the decreases in the levels of the brain-derived neurotrophic factor (bdnf) in the prefrontal cortex (pfc) and hippocampus (hip) of adult sprague-dawley rats, that have been induced by chronic administration of the model compound l-buthionine-(s, r)-sulfoximine (bso) during the early postnatal development (p5-p16). 2022-02-26 2022-02-28 Not clear
Jing Gao, Ming-Yin Lai, Thi Tanh-Tam Mai, Wen Fu, Meng-Yu Wang, Bai-le Ning, Wen-Bin F. [Effects of electroacupuncture on BNDF/mTORC1 signaling pathway and synaptic plasticity in prefrontal cortex of rats exposed to chronic unpredictable mild stress]. Zhen ci yan jiu = Acupuncture research vol 47 issue 1 2022 35128865 to investigate the effects of electroacupuncture (ea) on the expression of related proteins in the brain-derived neurotrophic factor (bdnf)/mammalian target of rapamycin complex 1 (mtorc1) signaling pathway and synapse-associated proteins and the density of dendrite spines in the prefrontal cortex (pfc) of depression model rats, and to reveal the underlying mechanism by which ea regulates the synaptic plasticity to improve depressive symptoms. 2022-02-07 2022-02-10 Not clear
Kohei Takahashi, Kazuhiro Kurokawa, Lihua Hong, Kazuya Miyagawa, Atsumi Mochida-Saito, Masahiro Iwasa, Hiroyuki Iwasa, Osamu Nakagawasai, Takeshi Tadano, Hiroshi Takeda, Minoru Tsuj. Antidepressant effects of Enterococcus faecalis 2001 through the regulation of prefrontal cortical myelination via the enhancement of CREB/BDNF and NF-\\xce\\xbaB p65/LIF/STAT3 pathways in olfactory bulbectomized mice. Journal of psychiatric research vol 148 issue 2022 35123326 further, ef-2001 treatment increased brain-derived neurotrophic factor (bdnf) and leukemia inhibitory factor (lif) in the pfc. 2022-02-05 2022-02-07 Not clear
J Blair Price, Clarissa G Yates, Brooke A Morath, Sam K Van De Wakker, Nathanael J Yates, Kim Butters, Mark A Frye, Sean L McGee, Susannah J Ty. Lithium augmentation of ketamine increases insulin signaling and antidepressant-like active stress coping in a rodent model of treatment-resistant depression. Translational psychiatry vol 11 issue 1 2021 34824208 prefrontal oxygen consumption rate (ocr) and extracellular acidification rates (ecar) were also determined in anterior pfc tissue at rest and following stimulation with brain-derived neurotrophic factor (bdnf) and tumor necrosis factor \xce\xb1 (tnf\xce\xb1). 2022-01-30 2022-01-13 Not clear
Yuan Zhou, Shao-Fu Li, Li-Sha Deng, Yong-Kang Ma, Gang Lei, Yong-Hui Dan. HINT1 deficiency in aged mice reduces anxiety-like and depression-like behaviours and enhances cognitive performances. Experimental gerontology vol issue 2022 34995725 in a battery of behavioural tests, aged wild-type mice showed increased anxiety-like and depression-like behaviours and decreased cognitive performance, along with lower expression levels of glutathione peroxidase, enhanced amount of malondialdehyde, and decreased expression levels of brain-derived neurotrophic factor and tyrosine kinase b in the hippocampus and pfc compared to young wild-type mice. 2022-01-30 2022-01-13 Not clear
Alessandro Virtuoso, Pernille Tveden-Nyborg, Anne Marie Voigt Schou-Pedersen, Jens Lykkesfeldt, Heidi Kaastrup M\\xc3\\xbcller, Betina Elfving, Dorte Bratbo S\\xc3\\xb8rense. A Long-Term Energy-Rich Diet Increases Prefrontal BDNF in Sprague-Dawley Rats. Nutrients vol 14 issue 1 2022 35011001 findings of the effect of high-fat feeding including "cafeteria diets" (caf) on brain-derived neurotrophic factor (bdnf) in the hippocampus (hip) and prefrontal cortex (pfc) in rodents are conflicting. 2022-01-11 2022-01-13 Not clear
Yuan Zhou, Shao-Fu Li, Li-Sha Deng, Yong-Kang Ma, Gang Lei, Yong-Hui Dan. HINT1 deficiency in aged mice reduces anxiety-like and depression-like behaviours and enhances cognitive performances. Experimental gerontology vol issue 2022 34995725 in a battery of behavioural tests, aged wild-type mice showed increased anxiety-like and depression-like behaviours and decreased cognitive performance, along with lower expression levels of glutathione peroxidase, enhanced amount of malondialdehyde, and decreased expression levels of brain-derived neurotrophic factor and tyrosine kinase b in the hippocampus and pfc compared to young wild-type mice. 2022-01-07 2022-01-13 Not clear
Jing Gao, Mingyin Lai, Wen Fu, Mengyu Wang, Thi Thanh Tam Mai, Baile Ning, Wenbin F. Electroacupuncture Ameliorates Depressive-Like State and Synaptic Deficits Induced by Hyper-Cholinergic Tone During Chronic Stress in Rats. Medical science monitor : international medical journal of experimental and clinical research vol 27 issue 2021 34924558 consistent with the behavior tests and cholinergic tones, there were increased spine density and expressions of synaptic proteins, including brain-derived neurotrophic factor (bdnf), glutamate receptor 1 (glur1), glutamate receptor 2 (glur2), postsynaptic density protein 95 (psd95), and synapsin i in the pfc. 2021-12-20 2022-01-13 Not clear
J Blair Price, Clarissa G Yates, Brooke A Morath, Sam K Van De Wakker, Nathanael J Yates, Kim Butters, Mark A Frye, Sean L McGee, Susannah J Ty. Lithium augmentation of ketamine increases insulin signaling and antidepressant-like active stress coping in a rodent model of treatment-resistant depression. Translational psychiatry vol 11 issue 1 2021 34824208 prefrontal oxygen consumption rate (ocr) and extracellular acidification rates (ecar) were also determined in anterior pfc tissue at rest and following stimulation with brain-derived neurotrophic factor (bdnf) and tumor necrosis factor \xce\xb1 (tnf\xce\xb1). 2021-12-11 2022-01-13 Not clear
Joko Poleksic, Milan Aksic, Slobodan Kapor, Dubravka Aleksic, Tihomir Stojkovic, Marina Radovic, Vuk Djulejic, Branka Markovic, Antonios Stamataki. Effects of Maternal Deprivation on the Prefrontal Cortex of Male Rats: Cellular, Neurochemical, and Behavioral Outcomes. Frontiers in behavioral neuroscience vol 15 issue 2021 34819843 furthermore, md induced upregulation of brain-derived neurotrophic factor (bdnf), while it did not affect the overall expression of iba1 in neonatal or young adult pfc as measured by western blot, however, microglial activation in young adult md rats was detected immunohistochemically in deep layers of mo and infralimbic cortex (il). 2021-11-26 2022-01-13 Not clear
Hakimeh Saadati, Farshid Sadegzadeh, Nona Sakhaie, Hamdollah Panahpour, Mohsen Sagh. Serotonin depletion during the postnatal developmental period causes behavioral and cognitive alterations and decreases BDNF level in the brain of rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience vol 81 issue 2 2021 33404066 therefore, in the present study, we examined the effects of postnatal days (pnd 10-20) administration of para-chlorophenylalanine (pcpa, 100\xc2\xa0mg/kg, s.c) a 5-ht synthesis inhibitor, on anxiety-related behaviors, pain sensitivity, short-term recognition memory, and hippocampal and prefrontal cortex (pfc) brain-derived neurotrophic factor (bdnf) mrna expression in adult male and female rats. 2021-11-18 2022-01-13 Not clear
Yufang Si, Xing Xue, Si Liu, Caixia Feng, Huiping Zhang, Sisi Zhang, Yating Ren, Hengyu Ma, Yankai Dong, Hui Li, Longshan Xie, Zhongliang Zh. CRTC1 signaling involvement in depression-like behavior of prenatally stressed offspring rat. Behavioural brain research vol 399 issue 2021 33161032 it was also found decreased levels of total crtc1, nuclear crtc1, calcineurin, brain-derived neurotrophic factor (bdnf) and c-fos, but increased cytoplasmic p-crtc1 in the hippocampus (hip) and prefrontal cortex (pfc) of the offspring rats. 2021-11-15 2022-01-13 Not clear
Janine Karina Hideko Alfenas Horita, Maria Carolina Machado da Silva, Carolina Zaniboni Ferrari, Erica Leandro Marciano Vieira, Fabricio A Moreira, Ant\\xc3\\xb4nio Carlos Pinheiro de Oliveira, Helton Jos\\xc3\\xa9 Rei. Evaluation of Brain Cytokines and the Level of Brain-Derived Neurotrophic Factor in an Inflammatory Model of Depression. Neuroimmunomodulation vol 27 issue 2 2021 33176302 inflammatory processes are likely involved in its pathophysiology, but the underlying mechanisms have remained uncertain.here, we used the model of systemic lipopolysaccharide (lps) injection to test the hypothesis that depressive-like behaviors occur along with changes in the levels of cytokines and brain-derived neurotrophic factor (bdnf) in the hippocampus (hc), prefrontal cortex (pfc), and hypothalamus (ht), and can be prevented by dexamethasone administration. 2021-10-28 2022-01-13 Not clear
Yunxia Niu, Tao Wang, Shan Liang, Wei Li, Xu Hu, Xiaoli Wu, Feng Ji. Sex-dependent aberrant PFC development in the adolescent offspring rats exposed to variable prenatal stress. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience vol 80 issue 6 2021 32358823 the study tested the concentration of brain-derived neurotrophic factor (bdnf), cluster of differentiation 68 (cd68), synaptotagmin-1(syt-1), 5-hydroxytryptamine (5-ht), dopamine (da), glucocorticoid receptors (grs) and oestrogen receptors (ers) in the pfc (prefrontal cortex). 2021-08-12 2022-01-13 Not clear
Roberta Str\\xc3\\xb6her Toledo, Dirson Jo\\xc3\\xa3o Stein, Paulo Roberto Stefani Sanches, Lisiane Santos da Silva, Helouise Richardt Medeiros, Felipe Fregni, Wolnei Caumo, Iraci L S Torre. rTMS induces analgesia and modulates neuroinflammation and neuroplasticity in neuropathic pain model rats. Brain research vol 1762 issue 2021 33737061 biochemical assays to assess the levels of brain-derived neurotrophic factor (bdnf), tumor necrosis factor-alpha (tnf-\xce\xb1), and interleukin (il)-10, were performed in the prefrontal cortex (pfc) and spinal cord tissue homogenates. 2021-08-11 2022-01-13 Not clear
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