| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Michelle Lima Garcez, Francielle Mina, Tatiani Bellettini-Santos, Fernanda Melo Ribeiro, Alessandra Zanette Ghisi Frassetto, Hemily Batista-Silva, Aline Pereira da Luz, Gustavo Luiz Schiavo, Eduarda Behenck Medeiros, Gabriel Casagrande Zabot, Lara Canever, Alexandra Ioppi Zugno, Josiane Budn. Folic Acid Supplementation in the Gestational Phase of Female Rats Improves Age-Related Memory Impairment and Neuroinflammation in Their Adult and Aged Offspring. The journals of gerontology. Series A, Biological sciences and medical sciences. vol 76. issue 6. 2021-09-15. PMID:33249457. |
in addition, natural aging and fa deficiency decreased brain-derived neurotrophic factor levels in the hippocampus and nerve growth factor levels in the prefrontal cortex and fa supplementation prevented it. |
2021-09-15 |
2023-08-13 |
rat |
| Zhaohong Qin, Li Zhang, Shelly A Cruz, Alexandre F R Stewart, Hsiao-Huei Che. Activation of tyrosine phosphatase PTP1B in pyramidal neurons impairs endocannabinoid signaling by tyrosine receptor kinase trkB and causes schizophrenia-like behaviors in mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 11. 2021-06-23. PMID:32610340. |
modulation of inhibitory inputs onto layer 2/3 pyramidal neurons of the prefrontal cortex relies on ecb signaling from the brain-derived neurotrophic factor receptor trkb, rather than mglur5, and this mechanism was defective in lmo4-deficient mice. |
2021-06-23 |
2023-08-13 |
mouse |
| Fu Li, Haitao Xiang, Jiashu Lu, Zhuo Chen, Chao Huang, Xiaomei Yua. Lycopene ameliorates PTSD-like behaviors in mice and rebalances the neuroinflammatory response and oxidative stress in the brain. Physiology & behavior. vol 224. 2021-06-21. PMID:32592701. |
lycopene treatment (20 mg/kg, 12 days) also suppressed the sps-induced decrease in brain derived neurotrophic factor (bdnf) levels in the hippocampus and prefrontal cortex in mice. |
2021-06-21 |
2023-08-13 |
mouse |
| Paola Rodrı Guez, Jessika Urbanavicius, José Pedro Prieto, Sara Fabius, Ana Laura Reyes, Vaclav Havel, Dalibor Sames, Cecilia Scorza, Ignacio Carrer. A Single Administration of the Atypical Psychedelic Ibogaine or Its Metabolite Noribogaine Induces an Antidepressant-Like Effect in Rats. ACS chemical neuroscience. vol 11. issue 11. 2021-06-18. PMID:32330007. |
we have recently reported that the acute ibogaine administration induced a long-term increase of brain-derived neurotrophic factor mrna levels in the rat prefrontal cortex, which led us to hypothesize that ibogaine may elicit antidepressant-like effects in rats. |
2021-06-18 |
2023-08-13 |
rat |
| Ksenia Musaelyan, Selin Yildizoglu, James Bozeman, Andrea Du Preez, Martin Egeland, Patricia A Zunszain, Carmine M Pariante, Cathy Fernandes, Sandrine Thure. Chronic stress induces significant gene expression changes in the prefrontal cortex alongside alterations in adult hippocampal neurogenesis. Brain communications. vol 2. issue 2. 2021-02-06. PMID:33543135. |
pathway analyses suggested huntingtin, leptin, myelin regulatory factor, methyl-cpg binding protein and brain-derived neurotrophic factor as the top predicted upstream regulators of transcriptomic changes in the prefrontal cortex. |
2021-02-06 |
2023-08-13 |
mouse |
| Gabriele C Pereira, Karine Roversi, Gabriela Trevisan, Marilise E Burger, Guilherme V Boch. Glucocorticoid and brain-derived neurotrophic factor relationship: a brief investigation into the model of depression by chronic administration of corticosterone. Behavioural pharmacology. vol 31. issue 4. 2021-01-29. PMID:32040016. |
moreover, the glucocorticoid receptor and tyrosine-receptor kinase b expression were increased in the hippocampus while the brain-derived neurotrophic factor expression was reduced in the prefrontal cortex. |
2021-01-29 |
2023-08-13 |
mouse |
| Rodrigo Moreno Klein, Camila Rigobello, Camila Borecki Vidigal, Kawane Fabrício Moura, Décio Sabbatini Barbosa, Daniela Cristina Ceccatto Gerardin, Graziela Scalianti Ceravolo, Estefânia Gastaldello Moreir. Gestational exposure to paracetamol in rats induces neurofunctional alterations in the progeny. Neurotoxicology and teratology. vol 77. 2021-01-25. PMID:31644948. |
moreover, lipid hidroperoxide (looh), reduced glutathione (gsh) and brain derived neurotrophic factor (bdnf) levels were quantified in prefrontal cortex and hippocampus of 22-days-old rats. |
2021-01-25 |
2023-08-13 |
rat |
| Stephanie M Gorka, Tara Teppen, Milena Radoman, K Luan Phan, Subhash C Pande. Human Plasma BDNF Is Associated With Amygdala-Prefrontal Cortex Functional Connectivity and Problem Drinking Behaviors. The international journal of neuropsychopharmacology. vol 23. issue 1. 2020-11-30. PMID:31722379. |
the association between brain-derived neurotrophic factor levels and amygdala function in humans with alcohol use disorder is still unclear, although neuroimaging studies have also implicated the amygdala in alcohol use disorder and suggest that alcohol use disorder is associated with disrupted functional connectivity between the amygdala and prefrontal cortex during aversive states. |
2020-11-30 |
2023-08-13 |
human |
| Ning Jiang, Haixia Wang, Jingwei Lv, Qiong Wang, Cong Lu, Yujiao Li, Xinmin Li. Dammarane sapogenins attenuates stress-induced anxiety-like behaviors by upregulating ERK/CREB/BDNF pathways. Phytotherapy research : PTR. vol 34. issue 10. 2020-11-30. PMID:32431006. |
treatment with ds significantly upregulated bdnf (brain-derived neurotrophic factor), p-creb/creb and p-erk1/2/erk1/2 protein expression in the hippocampus and prefrontal cortex of csds mice. |
2020-11-30 |
2023-08-13 |
mouse |
| Anderson Camargo, Ana Lúcia S Rodrigue. Novel Targets for Fast Antidepressant Responses: Possible Role of Endogenous Neuromodulators. Chronic stress (Thousand Oaks, Calif.). vol 3. 2020-09-28. PMID:32440595. |
the possibility that these neuromodulators and ketamine have common neurobiological mechanisms, mainly the ability to activate mechanistic target of rapamycin and brain-derived neurotrophic factor signaling, and synthesis of synaptic proteins in the prefrontal cortex and/or hippocampus is presented and discussed. |
2020-09-28 |
2023-08-13 |
Not clear |
| Takefumi Kikusui, Natsumi Kanbara, Mariya Ozaki, Nozomi Hirayama, Kumiko Ida, Mika Tokita, Naho Tanabe, Kuriko Mitsuyama, Hatsuki Abe, Miki Yoshida, Miho Nagasawa, Kazutaka Mog. Early weaning increases anxiety via brain-derived neurotrophic factor signaling in the mouse prefrontal cortex. Scientific reports. vol 9. issue 1. 2020-09-18. PMID:30850750. |
early weaning increases anxiety via brain-derived neurotrophic factor signaling in the mouse prefrontal cortex. |
2020-09-18 |
2023-08-13 |
mouse |
| Ismail O Ishola, Mmesomachukwu O Osele, Micah C Chijioke, Olufunmilayo O Adeyem. Isorhamnetin enhanced cortico-hippocampal learning and memory capability in mice with scopolamine-induced amnesia: Role of antioxidant defense, cholinergic and BDNF signaling. Brain research. vol 1712. 2020-09-11. PMID:30772273. |
one hour after probe test (mwm task) on day 7, the brains were isolated to assay for oxidative stress, cholinesterase activity and brain derived neurotrophic factor (bdnf) levels in the prefrontal cortex (pfc) and hippocampus (hippo). |
2020-09-11 |
2023-08-13 |
mouse |
| Betina Elfving, Heidi Kaastrup Müller, Ignasi Oliveras, Tina Becher Østerbøg, Cristobal Rio-Alamos, Ana Sanchez-Gonzalez, Adolf Tobeña, Alberto Fernandez-Teruel, Susana Azna. Differential expression of synaptic markers regulated during neurodevelopment in a rat model of schizophrenia-like behavior. Progress in neuro-psychopharmacology & biological psychiatry. vol 95. 2020-08-28. PMID:31228641. |
mrna levels of brain derived neurotrophic factor (bdnf) were increased in the pfc of the rha-i rats, with no differences in the hip, while bdnf protein levels were decreased in pfc and increased in hip. |
2020-08-28 |
2023-08-13 |
rat |
| Man-Man Zong, Hong-Mei Yuan, Xue He, Zhi-Qiang Zhou, Xiao-Dong Qiu, Jian-Jun Yang, Mu-Huo J. Disruption of Striatal-Enriched Protein Tyrosine Phosphatase Signaling Might Contribute to Memory Impairment in a Mouse Model of Sepsis-Associated Encephalopathy. Neurochemical research. vol 44. issue 12. 2020-03-30. PMID:31691882. |
the levels of step, phosphorylation of glun2b (pglun2b), the kinases extracellular signal-regulated kinase 1/2 (perk), camp-response element binding protein (creb), synaptophysin, brain derived neurotrophic factor (bdnf), and post-synaptic density protein 95 (psd95) in the hippocampus, prefrontal cortex, and striatum were determined at the indicated time points. |
2020-03-30 |
2023-08-13 |
mouse |
| Wei Hung Chang, I Hui Lee, Mei Hung Chi, Shih-Hsien Lin, Kao Chin Chen, Po See Chen, Nan Tsing Chiu, Wei Jen Yao, Yen Kuang Yan. Prefrontal cortex modulates the correlations between brain-derived neurotrophic factor level, serotonin, and the autonomic nervous system. Scientific reports. vol 8. issue 1. 2019-08-16. PMID:29416077. |
prefrontal cortex modulates the correlations between brain-derived neurotrophic factor level, serotonin, and the autonomic nervous system. |
2019-08-16 |
2023-08-13 |
human |
| Melissa L Perreault, Theresa Fan, Tomek J Banasikowski, Anthony A Grace, Susan R Georg. The atypical dopamine receptor agonist SKF 83959 enhances hippocampal and prefrontal cortical neuronal network activity in a rat model of cognitive dysfunction. The European journal of neuroscience. vol 46. issue 4. 2018-09-06. PMID:28677227. |
the atypical dopamine agonist skf 83959 has been shown to increase brain-derived neurotrophic factor signalling and suppress activity of glycogen synthase kinase-3 in pfc, two processes important to learning and memory. |
2018-09-06 |
2023-08-13 |
rat |
| Anjali Chawla, Zachary A Cordner, Gretha Boersma, Timothy H Mora. Cognitive impairment and gene expression alterations in a rodent model of binge eating disorder. Physiology & behavior. vol 180. 2018-05-14. PMID:28821448. |
aberrant gene expression of brain derived neurotrophic factor (bdnf) and tropomyosin receptor kinase b (trkb) in the hippocampus (hpc)-prefrontal cortex (pfc) network was observed in bep rats. |
2018-05-14 |
2023-08-13 |
rat |
| Zhuo Chen, Chao Huang, Haiyan He, Wenbin Din. 2, 3, 5, 4'-Tetrahydroxystilbene-2-O-β-D-glucoside prevention of lipopolysaccharide-induced depressive-like behaviors in mice involves neuroinflammation and oxido-nitrosative stress inhibition. Behavioural pharmacology. vol 28. issue 5. 2018-01-26. PMID:28410266. |
the lps-induced decreases in brain-derived neurotrophic factor levels in the hippocampus and prefrontal cortex were also prevented by tsg treatment. |
2018-01-26 |
2023-08-13 |
mouse |
| Xiuzhi Zhu, Rui Gao, Zhuxi Liu, Ziyi Cheng, Yihang Qi, Cuiqin Fan, Shu Yan Y. Ginsenoside Rg1 reverses stress-induced depression-like behaviours and brain-derived neurotrophic factor expression within the prefrontal cortex. The European journal of neuroscience. vol 44. issue 2. 2017-12-22. PMID:27062560. |
ginsenoside rg1 reverses stress-induced depression-like behaviours and brain-derived neurotrophic factor expression within the prefrontal cortex. |
2017-12-22 |
2023-08-13 |
rat |
| Xiuzhi Zhu, Rui Gao, Zhuxi Liu, Ziyi Cheng, Yihang Qi, Cuiqin Fan, Shu Yan Y. Ginsenoside Rg1 reverses stress-induced depression-like behaviours and brain-derived neurotrophic factor expression within the prefrontal cortex. The European journal of neuroscience. vol 44. issue 2. 2017-12-22. PMID:27062560. |
furthermore, chronic stress decreased the phosphorylation levels of the extracellular signal-regulated kinase and camp-response element-binding protein in the prefrontal cortex as well as producing a reduction of brain-derived neurotrophic factor expression. |
2017-12-22 |
2023-08-13 |
rat |