All Relations between brain derived neurotrophic factor and spinal cord posterior horn

Reference Sentence Publish Date Extraction Date Species
Zhi-Gang Yao, Xiao-Li Sun, Peng Li, Hong-Lei Liu, Hai-Long Wu, Zhi-Qiang Xi, Zhong-Hui Zhen. Neural stem cells transplantation alleviate the hyperalgesia of spinal cord injured (SCI) associated with down-regulation of BDNF. International journal of clinical and experimental medicine vol 8 issue 1 2015 25785011 immunohistochemistry and rt-pcr were used to demonstrate that expression of brain-derived neurotrophic factor (bdnf) in the superficial of the dorsal horn. 2015-03-18 2022-01-12 Not clear
Takahide Itokazu, Yasufumi Hayano, Ryosuke Takahashi, Toshihide Yamashit. Involvement of Wnt/\\xce\\xb2-catenin signaling in the development of neuropathic pain. Neuroscience research vol 79 issue 2014 24361264 because it was revealed that wnt3a treatment triggered brain-derived neurotrophic factor (bdnf) release from microglial cells in vitro, it is possible that wnt3a upregulation in the dorsal horn leads to the activation of microglial cells, then triggers bdnf secretion that is responsible for the establishment of neuropathic pain. 2014-11-01 2022-01-12 Not clear
Hong-Hai Zhang, Xiao-Qin Zhang, Qing-Sheng Xue, Yan-Luo, Jin-Lu Huang, Su Zhang, Hai-Jun Shao, Han Lu, Wen-Yuan Wang, Bu-Wei Y. The BDNF/TrkB signaling pathway is involved in heat hyperalgesia mediated by Cdk5 in rats. PloS one vol 9 issue 1 2014 24465591 the aim of this study was to determine whether roscovitine, an inhibitor of cdk5, could reverse the heat hyperalgesia induced by peripheral injection of complete freund's adjuvant (cfa) via the brain-derived neurotrophic factor (bdnf)-tyrosine kinase b (trkb) signaling pathway in the dorsal horn of the spinal cord in rats. 2014-10-27 2022-01-12 Not clear
Qian Xu, Minhao Zhang, Jian Liu, Weiyan L. Intrathecal transplantation of neural stem cells appears to alleviate neuropathic pain in rats through release of GDNF. Annals of clinical and laboratory science vol 43 issue 2 2013 23694790 in the present study, using the rat model of chronic constriction injury of the sciatic nerve, we observed the effect of intrathecal transplantation of extrinsic neural stem cells on the behavior and expression of neurotrophins such as brain-derived neurotrophic factor (bdnf) and glial cell line-derived neurotrophic factor (gdnf) in the spinal dorsal horn and dorsal root ganglia (drg), and analyzed bdnf and gdnf protein levels secreted by neural stem cells in vitro before and after differentiation. 2013-10-25 2022-01-12 Not clear
Simon Beggs, Tuan Trang, Michael W Salte. P2X4R+ microglia drive neuropathic pain. Nature neuroscience vol 15 issue 8 2012 22837036 stimulating p2x4 receptors initiates a core pain signaling pathway mediated by release of brain-derived neurotrophic factor, which produces a disinhibitory increase in intracellular chloride in nociceptive (pain-transmitting) neurons in the spinal dorsal horn. 2012-10-25 2022-01-12 Not clear
Cynthia L Renn, Carmen C Leitch, Sherrie Lessans, Peter Rhee, W Cameron McGuire, Barbara A Smith, Richard J Traub, Susan G Dorse. Brain-derived neurotrophic factor modulates antiretroviral-induced mechanical allodynia in the mouse. Journal of neuroscience research vol 89 issue 10 2012 21647939 this study examines the role of brain-derived neurotrophic factor (bdnf) in the spinal dorsal horn (sdh) in development of mechanical allodynia in male c57bl/6j mice treated with the nrti stavudine (d4t). 2012-06-04 2022-01-12 Not clear
Pedro Cruz Duarte, Bruno St-Jacques, Weiya M. Prostaglandin E2 contributes to the synthesis of brain-derived neurotrophic factor in primary sensory neuron in ganglion explant cultures and in a neuropathic pain model. Experimental neurology vol 234 issue 2 2012 22309829 brain-derived neurotrophic factor (bdnf) exists in small to medium size neurons in adult rat dorsal root ganglion (drg) and serves as a modulator at the first synapse of the pain transmission pathway in the spinal dorsal horn. 2012-05-04 2022-01-12 Not clear
X Zhang, J Wang, Q Zhou, Y Xu, S Pu, J Wu, Y Xue, Y Tian, J Lu, W Jiang, D D. Brain-derived neurotrophic factor-activated astrocytes produce mechanical allodynia in neuropathic pain. Neuroscience vol 199 issue 2012 22044922 we have found increased glial fibrillary acidic protein (gfap) expression, a hallmark of reactive gliosis, and elevated brain-derived neurotrophic factor (bdnf) expression in the dorsal horn in a rat model of allodynia induced by spinal nerve ligation (snl). 2012-04-06 2022-01-12 Not clear
Ya-Tin Lin, Long-Sun Ro, Hung-Li Wang, Jin-Chung Che. Up-regulation of dorsal root ganglia BDNF and trkB receptor in inflammatory pain: an in vivo and in vitro study. Journal of neuroinflammation vol 8 issue 2012 21958434 brain-derived neurotrophic factor (bdnf) plays a neuromodulatory role in spinal cord dorsal horn via the post-synaptic tyrosine protein kinase b (trkb) receptor to facilitate pain transmission. 2012-03-30 2022-01-12 Not clear
Simon Beggs, Michael W Salte. Microglia-neuronal signalling in neuropathic pain hypersensitivity 2.0. Current opinion in neurobiology vol 20 issue 4 2011 20817512 the core signalling pathway is through p2x4 purinergic receptors on the microglia which, via the release of brain-derived neurotrophic factor, cause disinhibition of nociceptive dorsal horn neurons by raising intracellular chloride levels. 2011-01-06 2022-01-12 Not clear
Van B Lu, James E Biggs, Martin J Stebbing, Sridhar Balasubramanyan, Kathryn G Todd, Aaron Y Lai, William F Colmers, David Dawbarn, Klaus Ballanyi, Peter A Smit. Brain-derived neurotrophic factor drives the changes in excitatory synaptic transmission in the rat superficial dorsal horn that follow sciatic nerve injury. The Journal of physiology vol 587 issue Pt 5 2009 19124536 brain-derived neurotrophic factor drives the changes in excitatory synaptic transmission in the rat superficial dorsal horn that follow sciatic nerve injury. 2009-12-07 2022-01-12 Not clear
V B Lu, W F Colmers, P A Smit. Long-term effects of brain-derived neurotrophic factor on the frequency of inhibitory synaptic events in the rat superficial dorsal horn. Neuroscience vol 161 issue 4 2009 19376198 long-term effects of brain-derived neurotrophic factor on the frequency of inhibitory synaptic events in the rat superficial dorsal horn. 2009-08-25 2022-01-12 Not clear
Vanja Duric, Kenneth E McCarso. Neurokinin-1 (NK-1) receptor and brain-derived neurotrophic factor (BDNF) gene expression is differentially modulated in the rat spinal dorsal horn and hippocampus during inflammatory pain. Molecular pain vol 3 issue 2008 17974009 neurokinin-1 (nk-1) receptor and brain-derived neurotrophic factor (bdnf) gene expression is differentially modulated in the rat spinal dorsal horn and hippocampus during inflammatory pain. 2008-02-21 2022-01-12 Not clear
Van B Lu, Klaus Ballanyi, William F Colmers, Peter A Smit. Neuron type-specific effects of brain-derived neurotrophic factor in rat superficial dorsal horn and their relevance to 'central sensitization'. The Journal of physiology vol 584 issue Pt 2 2008 17761774 neuron type-specific effects of brain-derived neurotrophic factor in rat superficial dorsal horn and their relevance to 'central sensitization'. 2008-01-10 2022-01-12 Not clear
Taro Kato, Ritsuko Ohtani-Kaneko, Takashi Shig. Dorsal root ganglion regulates the transient ERK activation in the dorsal horn of the spinal cord during development. Neuroscience research vol 58 issue 4 2007 17532077 brain-derived neurotrophic factor (bdnf) activated erk in the dorsal horn, and anti-bdnf blocked the drg-induced erk activation. 2007-12-10 2022-01-12 Not clear
Koichi Obata, Koichi Noguch. BDNF in sensory neurons and chronic pain. Neuroscience research vol 55 issue 1 2006 16516994 brain-derived neurotrophic factor (bdnf), synthesized in the primary sensory neurons, is anterogradely transported to the central terminals of the primary afferents in the spinal dorsal horn, where it is involved in the modulation of painful stimuli. 2006-07-13 2022-01-13 Not clear
Fuad A Abdulla, Timothy D Moran, Sridhar Balasubramanyan, Peter A Smit. Effects and consequences of nerve injury on the electrical properties of sensory neurons. Canadian journal of physiology and pharmacology vol 81 issue 7 2004 12897814 peptides such as substance p, neuropeptide y (npy), calcitonin-gene-related peptide (cgrp), and brain-derived neurotrophic factor (bdnf) may promote enduring changes in excitability as a consequence of neurotrophic actions on ion channel expression in the dorsal horn. 2004-03-22 2022-01-11 Not clear
Akira Onda, Yasuaki Murata, Bj\\xc3\\xb6rn Rydevik, Karin Larsson, Shinichi Kikuchi, Kjell Olmarke. Immunoreactivity of brain-derived neurotrophic factor in rat dorsal root ganglion and spinal cord dorsal horn following exposure to herniated nucleus pulposus. Neuroscience letters vol 352 issue 1 2004 14615047 immunoreactivity of brain-derived neurotrophic factor in rat dorsal root ganglion and spinal cord dorsal horn following exposure to herniated nucleus pulposus. 2004-01-20 2022-01-12 Not clear
Akira Onda, Yasuaki Murata, Bj\\xc3\\xb6rn Rydevik, Karin Larsson, Shinichi Kikuchi, Kjell Olmarke. Immunoreactivity of brain-derived neurotrophic factor in rat dorsal root ganglion and spinal cord dorsal horn following exposure to herniated nucleus pulposus. Neuroscience letters vol 352 issue 1 2004 14615047 this study assessed changes in brain-derived neurotrophic factor (bdnf) expression, a modulator of nociceptive information, in the dorsal root ganglion (drg) and spinal cord dorsal horn following experimental disc herniation. 2004-01-20 2022-01-12 Not clear
Sandra M Garraway, Jeffrey C Petruska, Lorne M Mendel. BDNF sensitizes the response of lamina II neurons to high threshold primary afferent inputs. The European journal of neuroscience vol 18 issue 9 2004 14622147 brain-derived neurotrophic factor (bdnf) is up-regulated and released in the dorsal horn following peripheral inflammation and has therefore been implicated in spinal mechanisms of sensitization. 2004-01-16 2022-01-12 Not clear
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