| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Valentina Carotti, Wouter H van Megen, Juan P Rigalli, Eric R Barros, Vera Sommers, Luco Rutten, Nico Sommerdijk, Dorien J M Peters, Jenny van Asbeck-van der Wijst, Joost G J Hoendero. Extracellular vesicles contribute to early cyst development in autosomal dominant polycystic kidney disease by cell-to-cell communication. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 37. issue 7. 2023-05-30. PMID:37249915. |
given that evs are an important communicator between different nephron segments, we hypothesize that evs released from pkd1 knockout distal convoluted tubule (dct) cells can stimulate cyst growth in the downstream collecting duct (cd). |
2023-05-30 |
2023-08-14 |
Not clear |
| Beatrix Sarkany, Gyula Kovac. Connecting tubules develop from the tip of the ureteric bud in the human kidney. Histochemistry and cell biology. 2021-09-23. PMID:34554322. |
the connecting tubule (cnt) is a unique segment of the nephron connecting the metanephric mesenchyme (mm)-derived distal convoluted tubule (dct) and ureteric bud (ub)-derived collecting duct (cd). |
2021-09-23 |
2023-08-13 |
mouse |
| Jacques Teulon, Wen-Hui Wan. Studying Na Methods in cell biology. vol 153. 2020-05-04. PMID:31395377. |
studying na aldosterone-sensitive distal nephron (asdn) including the distal convoluted tubule (dct), connecting tubule (cnt) and collecting duct (cd) plays an important role in the regulation of hormone-dependent na |
2020-05-04 |
2023-08-13 |
Not clear |
| Wencui Zheng, Jill W Verlander, I Jeanette Lynch, Melanie Cash, Jiahong Shao, Lisa R Stow, Brian D Cain, I David Weiner, Susan M Wall, Charles S Wing. Cellular distribution of the potassium channel KCNQ1 in normal mouse kidney. American journal of physiology. Renal physiology. vol 292. issue 1. 2007-02-12. PMID:16896189. |
rt-pcr showed kcnq1 mrna in isolated distal convoluted tubule (dct), connecting segment (cnt), collecting ducts (cd), and glomeruli. |
2007-02-12 |
2023-08-12 |
mouse |
| Isabelle Rubera, Johannes Loffing, Lawrence G Palmer, Gustavo Frindt, Nicole Fowler-Jaeger, Daniel Sauter, Tom Carroll, Andrew McMahon, Edith Hummler, Bernard C Rossie. Collecting duct-specific gene inactivation of alphaENaC in the mouse kidney does not impair sodium and potassium balance. The Journal of clinical investigation. vol 112. issue 4. 2003-09-24. PMID:12925696. |
we have tested this hypothesis by inactivating the alpha subunit of enac in the cd but leaving enac expression in the late dct and cnt intact. |
2003-09-24 |
2023-08-12 |
mouse |
| T Yang, S Hassan, Y G Huang, A M Smart, J P Briggs, J B Schnerman. Expression of PTHrP, PTH/PTHrP receptor, and Ca(2+)-sensing receptor mRNAs along the rat nephron. The American journal of physiology. vol 272. issue 6 Pt 2. 1997-08-18. PMID:9227636. |
presence of pth/pthrp receptor mrna was demonstrated in glomeruli, pct, pst, ctal, mtal, and dct but not in cd segments. |
1997-08-18 |
2023-08-12 |
mouse |
| T Yang, S Hassan, Y G Huang, A M Smart, J P Briggs, J B Schnerman. Expression of PTHrP, PTH/PTHrP receptor, and Ca(2+)-sensing receptor mRNAs along the rat nephron. The American journal of physiology. vol 272. issue 6 Pt 2. 1997-08-18. PMID:9227636. |
pthrp mrna was predominantly expressed in glomeruli and at lower levels in pct and the macula densacontaining segment but was not detectable in ctal, mtal, dct, and cd segments. |
1997-08-18 |
2023-08-12 |
mouse |