| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Will W Minut. Installation of the developing nephron in the fetal human kidney during advanced pregnancy. Molecular and cellular pediatrics. vol 10. issue 1. 2023-11-27. PMID:38012334. |
it is not known in how far also the involved progenitor cells, the earlier nephron stages, the collecting duct (cd) ampullae, and the local interstitium are collaterally harmed. |
2023-11-27 |
2023-11-29 |
human |
| Valentina Carotti, Wouter H van Megen, Juan P Rigalli, Eric R Barros, Vera Sommers, Luco Rutten, Nico Sommerdijk, Dorien J M Peters, Jenny van Asbeck-van der Wijst, Joost G J Hoendero. Extracellular vesicles contribute to early cyst development in autosomal dominant polycystic kidney disease by cell-to-cell communication. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 37. issue 7. 2023-05-30. PMID:37249915. |
given that evs are an important communicator between different nephron segments, we hypothesize that evs released from pkd1 knockout distal convoluted tubule (dct) cells can stimulate cyst growth in the downstream collecting duct (cd). |
2023-05-30 |
2023-08-14 |
Not clear |
| Nahid Tabibzadeh, Gilles Cramber. Mechanistic insights into the primary and secondary alterations of renal ion and water transport in the distal nephron. Journal of internal medicine. 2022-08-01. PMID:35909256. |
alterations of the functions of the collecting duct (cd), the most distal part of the nephron, have been extensively studied and have led to a better diagnosis, better management of the related diseases and the development of therapeutic tools. |
2022-08-01 |
2023-08-14 |
Not clear |
| Anastasia V Sudarikova, Mikhail V Fomin, Regina F Sultanova, Ying Zhao, Samantha Perez, Mark Domondon, Margarita Shamatova, Daria V Lysikova, Denisha R Spires, Daria V Ilatovskay. Functional role of histamine receptors in the renal cortical collecting duct cells. American journal of physiology. Cell physiology. 2022-01-26. PMID:35081320. |
the goal of this study was to provide insight into the role of histamine-related pathways in the kidney, with emphasis on the collecting duct (cd), a distal part of the nephron important for the regulation of blood pressure. |
2022-01-26 |
2023-08-13 |
mouse |
| Beatrix Sarkany, Gyula Kovac. Connecting tubules develop from the tip of the ureteric bud in the human kidney. Histochemistry and cell biology. 2021-09-23. PMID:34554322. |
the connecting tubule (cnt) is a unique segment of the nephron connecting the metanephric mesenchyme (mm)-derived distal convoluted tubule (dct) and ureteric bud (ub)-derived collecting duct (cd). |
2021-09-23 |
2023-08-13 |
mouse |
| Brian N Chorley, Heidrun Ellinger-Ziegelbauer, Michael Tackett, Frank J Simutis, Alison H Harrill, James McDuffie, Elnaz Atabakhsh, Rounak Nassirpour, Laurence O Whiteley, Jean-François Léonard, Gleta K Carswell, Ernie Harpur, Connie L Chen, Jean-Charles Gautie. Urinary miRNA Biomarkers of Drug-Induced Kidney Injury and Their Site Specificity Within the Nephron. Toxicological sciences : an official journal of the Society of Toxicology. vol 180. issue 1. 2021-08-18. PMID:33367795. |
rats were treated with nephrotoxicants causing injury to distinct nephron segments: the glomerulus, proximal tubule, thick ascending limb (tal) of the loop of henle and cd. |
2021-08-18 |
2023-08-13 |
rat |
| Zipeng Zeng, Biao Huang, Riana K Parvez, Yidan Li, Jyunhao Chen, Ariel C Vonk, Matthew E Thornton, Tadrushi Patel, Elisabeth A Rutledge, Albert D Kim, Jingying Yu, Brendan H Grubbs, Jill A McMahon, Nuria M Pastor-Soler, Kenneth R Hallows, Andrew P McMahon, Zhongwei L. Generation of patterned kidney organoids that recapitulate the adult kidney collecting duct system from expandable ureteric bud progenitors. Nature communications. vol 12. issue 1. 2021-07-12. PMID:34131121. |
current kidney organoids model development and diseases of the nephron but not the contiguous epithelial network of the kidney's collecting duct (cd) system. |
2021-07-12 |
2023-08-13 |
mouse |
| Andrew C Curnow, Sabrina R Gonsalez, Venkateswara R Gogulamudi, Bruna Visniauskas, Eric E Simon, Alexis A Gonzalez, Dewan S A Majid, Lucienne S Lara, Minolfa C Priet. Low Nitric Oxide Bioavailability Increases Renin Production in the Collecting Duct. Frontiers in physiology. vol 11. 2020-12-08. PMID:33281610. |
the cd is a major nephron segment for the synthesis of nitric oxide (no), and low no bioavailability in the renal medulla is associated with hypertension. |
2020-12-08 |
2023-08-13 |
mouse |
| Hu Peng, Jeffrey M Purkerson, Robert S Freeman, Andrew L Schwaderer, George J Schwart. Acidosis induces antimicrobial peptide expression and resistance to uropathogenic American journal of physiology. Renal physiology. vol 318. issue 2. 2020-05-11. PMID:31841391. |
since the collecting duct (cd) plays a pivotal role in regulating acid-base homeostasis and is the first nephron segment encountered by an ascending microbial infection, we examined the contribution of hif-1α to innate immune responses elicited by acid loading of an m-1 immortalized mouse cd cell line. |
2020-05-11 |
2023-08-13 |
mouse |
| Jacques Teulon, Wen-Hui Wan. Studying Na Methods in cell biology. vol 153. 2020-05-04. PMID:31395377. |
studying na aldosterone-sensitive distal nephron (asdn) including the distal convoluted tubule (dct), connecting tubule (cnt) and collecting duct (cd) plays an important role in the regulation of hormone-dependent na |
2020-05-04 |
2023-08-13 |
Not clear |
| Johannes Stegbauer, Daian Chen, Marcela Herrera, Matthew A Sparks, Ting Yang, Eva Königshausen, Susan B Gurley, Thomas M Coffma. Resistance to hypertension mediated by intercalated cells of the collecting duct. JCI insight. vol 2. issue 7. 2019-07-03. PMID:28405625. |
the renal collecting duct (cd), as the terminal segment of the nephron, is responsible for the final adjustments to the amount of sodium excreted in urine. |
2019-07-03 |
2023-08-13 |
mouse |
| N Ramkumar, D Stuart, N Abraham, D E Koha. Nephron prorenin receptor deficiency alters renal medullary endothelin-1 and endothelin receptor expression. Physiological research. vol 67. issue Suppl 1. 2018-10-15. PMID:29947533. |
it is unknown if the cd et and renin/prr systems interact, hence we examined the effects of deleting cd renin or nephron prr on cd et system components. |
2018-10-15 |
2023-08-13 |
mouse |
| N Ramkumar, D Stuart, N Abraham, D E Koha. Nephron prorenin receptor deficiency alters renal medullary endothelin-1 and endothelin receptor expression. Physiological research. vol 67. issue Suppl 1. 2018-10-15. PMID:29947533. |
taken together, these results suggest that the nephron prr is involved in regulating cd et system expression, but this effect may be independent of cd-derived renin. |
2018-10-15 |
2023-08-13 |
mouse |
| Frank Thévenod, Natascha A Wolf. Iron transport in the kidney: implications for physiology and cadmium nephrotoxicity. Metallomics : integrated biometal science. vol 8. issue 1. 2016-10-14. PMID:26485516. |
accordingly fe transporters and receptors for protein-bound fe are expressed in the nephron that may also function as entry pathways for toxic metals, such as cadmium (cd), by way of "ionic and molecular mimicry". |
2016-10-14 |
2023-08-13 |
Not clear |
| Rong Rong, Osamu Ito, Nobuyoshi Mori, Yoshikazu Muroya, Yuma Tamura, Takefumi Mori, Sadayoshi Ito, Kazuhiro Takahashi, Kazuhito Totsune, Masahiro Kohzuk. Expression of (pro)renin receptor and its upregulation by high salt intake in the rat nephron. Peptides. vol 63. 2016-09-05. PMID:25555681. |
(p)rr mrna was expressed in various nephron segments of the cortex and medulla; glomeruli (glm), proximal tubules (pt), thick ascending limbs (tal) and collecting ducts (cd). |
2016-09-05 |
2023-08-13 |
rat |
| I Jeanette Lynch, Amanda K Welch, Michelle L Gumz, Donald E Kohan, Brian D Cain, Charles S Wing. Effect of mineralocorticoid treatment in mice with collecting duct-specific knockout of endothelin-1. American journal of physiology. Renal physiology. vol 309. issue 12. 2016-04-20. PMID:26400543. |
aldosterone increases blood pressure (bp) by stimulating sodium (na) reabsorption within the distal nephron and collecting duct (cd). |
2016-04-20 |
2023-08-13 |
mouse |
| Nirupama Ramkumar, Donald E Koha. Role of collecting duct renin in blood pressure regulation. American journal of physiology. Regulatory, integrative and comparative physiology. vol 305. issue 2. 2013-09-26. PMID:23637136. |
preliminary studies suggest that the net effect of cd renin would be to increase distal nephron salt reabsorption and increase blood pressure. |
2013-09-26 |
2023-08-12 |
Not clear |
| Viatcheslav Nesterov, Anke Dahlmann, Bettina Krueger, Marko Bertog, Johannes Loffing, Christoph Korbmache. Aldosterone-dependent and -independent regulation of the epithelial sodium channel (ENaC) in mouse distal nephron. American journal of physiology. Renal physiology. vol 303. issue 9. 2013-01-24. PMID:22933298. |
aldosterone is thought to be the main hormone to stimulate the epithelial sodium channel (enac) in the aldosterone-sensitive distal nephron (asdn) comprising the late distal convoluted tubule (dct2), the connecting tubule (cnt) and the entire collecting duct (cd). |
2013-01-24 |
2023-08-12 |
mouse |
| James B Wade, Liang Fang, Richard A Coleman, Jie Liu, P Richard Grimm, Tong Wang, Paul A Wellin. Differential regulation of ROMK (Kir1.1) in distal nephron segments by dietary potassium. American journal of physiology. Renal physiology. vol 300. issue 6. 2011-08-05. PMID:21454252. |
characterization with segmental markers revealed a more extensive pattern of romk expression along the entire distal nephron than previously thought, localizing to distal convoluted tubule regions, dct1 and dct2; the connecting tubule (cnt); and cortical collecting duct (cd). |
2011-08-05 |
2023-08-12 |
mouse |
| James B Wade, Liang Fang, Richard A Coleman, Jie Liu, P Richard Grimm, Tong Wang, Paul A Wellin. Differential regulation of ROMK (Kir1.1) in distal nephron segments by dietary potassium. American journal of physiology. Renal physiology. vol 300. issue 6. 2011-08-05. PMID:21454252. |
we conclude 1) our new antibody provides a unique tool to characterize romk channel localization and expression and 2) high-k diet causes a large increase in apical expression of romk in dct2, cnt, and cd but not in dct1, indicating that different regulatory mechanisms are involved in k diet-regulated romk channel functions in the distal nephron. |
2011-08-05 |
2023-08-12 |
mouse |