All Relations between comt and drd4

Publication Sentence Publish Date Extraction Date Species
A E Gareeva, K O Kinyasheva, D Yu Galaktionova, E T Sabirov, R G Valinourov, A V Chudinov, A S Zasedatelev, T V Nasedkina, E K Khusnutdinov. [Brain neurotransmitter systems gene Polymorphism: the Search for pharmacogenetic markers of efficacy of haloperidol in Russians and Tatars]. Molekuliarnaia biologiia. vol 49. issue 6. 2016-02-23. PMID:26710776. in this paper, we analyzed the association of nine polymorphic variants of five genes of dopaminergic and serotonergic systems drd4, htr2a, tph1, slc18a1, comt in russian and tatars patients living in the republic of bashkortostan (rb) with the efficiency of a typical antipsychotic haloperidol on the scale of positive and negative systems of panss. 2016-02-23 2023-08-13 Not clear
A E Gareeva, K O Kinyasheva, D Yu Galaktionova, E T Sabirov, R G Valinourov, A V Chudinov, A S Zasedatelev, T V Nasedkina, E K Khusnutdinov. [Brain neurotransmitter systems gene Polymorphism: the Search for pharmacogenetic markers of efficacy of haloperidol in Russians and Tatars]. Molekuliarnaia biologiia. vol 49. issue 6. 2016-02-23. PMID:26710776. the results of this study confirm the importance of changes in the nucleotide sequences of the studied genes of the serotoninergic and dopaminergic systems (htr2a, tph1, slc18a1 comt, drd4) in the formation of individual sensitivity to haloperidol. 2016-02-23 2023-08-13 Not clear
Weidong Ji, Ning Li, Kang Ju, Hong Zheng, Chuang Yang, Ping Xu, Silu Chen, Aiai Cao, Xue Chen, Lanting Gu. Association of Catechol-O-methyltransferase val/met polymorphism with cognitive function in Gilles de la Tourette syndrome patients. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 36. issue 4. 2015-12-09. PMID:25367405. the mechanism of cognitive functions was associated with dopaminergic system, thus we access the associations between polymorphism of some dopaminergic system-related genes including catechol-o-methyltransferase (comt) met/val, dopamine receptor d4 (drd4) exon iii 48 bp vntr (variable number of tandem repeats), interleukin 1 (il-1) ra 86 bp and il-1β exon 5, and cognitive functions in gts patients. 2015-12-09 2023-08-13 Not clear
Gordana Nedic Erjavec, Korona Nenadic Sviglin, Matea Nikolac Perkovic, Dorotea Muck-Seler, Tanja Jovanovic, Nela Piva. Association of gene polymorphisms encoding dopaminergic system components and platelet MAO-B activity with alcohol dependence and alcohol dependence-related phenotypes. Progress in neuro-psychopharmacology & biological psychiatry. vol 54. 2015-05-12. PMID:25035107. the present study aimed to evaluate the association of alcohol dependence and alcohol dependence-related phenotypes with platelet monoamine oxidase type b (mao-b) activity, val108/158met of catechol-o-methyltransferase (comt), variable number of tandem repeats (vntr) in the third exon of dopamine receptor d4 (drd4) gene, vntr in the 3'-untranslated region of dopamine transporter (dat) gene, -1021c/t of dopamine beta-hydroxylase (dbh) and mao-b intron 13 polymorphisms. 2015-05-12 2023-08-13 human
Margarita Alfimova, Galina Korovaitseva, Tatiana Lezheiko, Vera Golimbe. Interaction effects of the COMT and DRD4 genes with anxiety-related traits on selective attention. The Spanish journal of psychology. vol 17. 2015-04-01. PMID:25011686. interaction effects of the comt and drd4 genes with anxiety-related traits on selective attention. 2015-04-01 2023-08-13 human
Margarita Alfimova, Galina Korovaitseva, Tatiana Lezheiko, Vera Golimbe. Interaction effects of the COMT and DRD4 genes with anxiety-related traits on selective attention. The Spanish journal of psychology. vol 17. 2015-04-01. PMID:25011686. the study investigated whether the drd4 and comt genes can modify relations between trait anxiety and selective attention. 2015-04-01 2023-08-13 human
Margarita Alfimova, Galina Korovaitseva, Tatiana Lezheiko, Vera Golimbe. Interaction effects of the COMT and DRD4 genes with anxiety-related traits on selective attention. The Spanish journal of psychology. vol 17. 2015-04-01. PMID:25011686. genotypes for the comt val158met and drd4 vntr-48 polymorphisms and tci harm avoidance and mmpi depression scales' scores were obtained as well. 2015-04-01 2023-08-13 human
P Grant, F Gabriel, Y Kuepper, C Wielpuetz, J Henni. Psychosis-proneness correlates with expression levels of dopaminergic genes. European psychiatry : the journal of the Association of European Psychiatrists. vol 29. issue 5. 2015-02-20. PMID:24630741. we found significant negative correlations regarding the expression of the genes comt, maob, drd4, drd5 and fos, indicating that increased schizotypy coincides with higher levels of dopaminergic dysregulation on the mrna-level. 2015-02-20 2023-08-12 human
Caterina Iofrida, Sara Palumbo, Silvia Pellegrin. Molecular genetics and antisocial behavior: where do we stand? Experimental biology and medicine (Maywood, N.J.). vol 239. issue 11. 2015-01-05. PMID:24764243. in this paper, we review the findings regarding four polymorphisms-maoa (monoamine oxidase a) uvntr, slc6a4 (solute carrier family 6 (neurotransmitter transporter), member 4) 5httlpr, comt (catechol-o-methyltransferase) val158met and drd4 (dopamine d4 receptor) vntr 1-11-that all have been found to be associated with an increased vulnerability for antisocial and impulsive behavior in response to aversive environmental conditions. 2015-01-05 2023-08-13 human
Eliana Marisa Ramos, Jeanne C Latourelle, Tammy Gillis, Jayalakshmi S Mysore, Ferdinando Squitieri, Alba Di Pardo, Stefano Di Donato, Cinzia Gellera, Michael R Hayden, Patrick J Morrison, Martha Nance, Christopher A Ross, Russell L Margolis, Estrella Gomez-Tortosa, Carmen Ayuso, Oksana Suchowersky, Ronald J Trent, Elizabeth McCusker, Andrea Novelletto, Marina Frontali, Randi Jones, Tetsuo Ashizawa, Samuel Frank, Marie-Helene Saint-Hilaire, Steven M Hersch, Herminia D Rosas, Diane Lucente, Madaline B Harrison, Andrea Zanko, Ruth K Abramson, Karen Marder, James F Gusella, Jong-Min Lee, Isabel Alonso, Jorge Sequeiros, Richard H Myers, Marcy E Macdonal. Candidate glutamatergic and dopaminergic pathway gene variants do not influence Huntington's disease motor onset. Neurogenetics. vol 14. issue 3-4. 2014-06-23. PMID:23644918. we used genetic association analysis in 1,628 hd patients to evaluate candidate polymorphisms in n-methyl-d-aspartate receptor subtype genes (grin2a rs4998386 and rs2650427, and grin2b rs1806201) and functional polymorphisms in genes in the dopamine pathway (dat1 3' utr 40-bp variable number tandem repeat (vntr), drd4 exon 3 48-bp vntr, drd2 rs1800497, and comt rs4608) as potential modifiers of the disease process. 2014-06-23 2023-08-12 Not clear
Paramita Ghosh, Kanyakumarika Sarkar, Nipa Bhaduri, Anirban Ray, Keka Sarkar, Swagata Sinha, Kanchan Mukhopadhya. Catecholaminergic gene variants: contribution in ADHD and associated comorbid attributes in the eastern Indian probands. BioMed research international. vol 2013. 2014-06-23. PMID:24163823. we have assessed variants in four genes, ddc (rs3837091 and rs3735273), drd2 (rs1800496, rs1801028, and rs1799732), drd4 (rs4646984 and rs4646983), and comt (rs165599 and rs740603) in indian adhd subjects with comorbid attributes. 2014-06-23 2023-08-12 human
Guillermo Gervasini, Inmaculada Gordillo, Angustias García-Herráiz, Isalud Flores, Mercedes Jiménez, Melchora Monge, Juan Antonio Carrill. Influence of dopamine polymorphisms on the risk for anorexia nervosa and associated psychopathological features. Journal of clinical psychopharmacology. vol 33. issue 4. 2014-02-18. PMID:23775054. we have analyzed the effect of 8 polymorphisms in genes coding for dopamine receptors (drd2, drd3, and drd4), transporters (dat1) and metabolizing enzymes (comt) in 78 women with an and 186 control subjects. 2014-02-18 2023-08-12 human
P J Carpentier, A Arias Vasquez, M Hoogman, M Onnink, C C Kan, J J S Kooij, R Makkinje, S Iskandar, L A Kiemeney, C A J de Jong, B Franke, J K Buitelaa. Shared and unique genetic contributions to attention deficit/hyperactivity disorder and substance use disorders: a pilot study of six candidate genes. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 23. issue 6. 2013-12-23. PMID:22841130. one hundred seven methadone maintenance treatment patients, 36 having an adhd diagnosis, 176 adult patients with adhd without suds, and 500 healthy controls were genotyped for variants in the drd4 (exon 3 vntr), drd5 (upstream vntr), htr1b (rs6296), dbh (rs2519152), comt (rs4680; val158met), and oprm1 (rs1799971; 118a>g) genes. 2013-12-23 2023-08-12 Not clear
Sebastian Heinzel, Thomas Dresler, Christina G Baehne, Monika Heine, Andrea Boreatti-Hümmer, Christian P Jacob, Tobias J Renner, Andreas Reif, Klaus-Peter Lesch, Andreas J Fallgatter, Ann-Christine Ehli. COMT x DRD4 epistasis impacts prefrontal cortex function underlying response control. Cerebral cortex (New York, N.Y. : 1991). vol 23. issue 6. 2013-12-04. PMID:22617852. comt x drd4 epistasis impacts prefrontal cortex function underlying response control. 2013-12-04 2023-08-12 human
Sebastian Heinzel, Thomas Dresler, Christina G Baehne, Monika Heine, Andrea Boreatti-Hümmer, Christian P Jacob, Tobias J Renner, Andreas Reif, Klaus-Peter Lesch, Andreas J Fallgatter, Ann-Christine Ehli. COMT x DRD4 epistasis impacts prefrontal cortex function underlying response control. Cerebral cortex (New York, N.Y. : 1991). vol 23. issue 6. 2013-12-04. PMID:22617852. catechol-o-methyltransferase (comt; val158met) and da d4-receptor (drd4; 48 bp vntr) genotypes were analyzed for effects on behavioral and neural correlates of prefrontal response control (nogo-anteriorization, nga) using a go-nogo task and electroencephalography (114 controls and 181 patients with attention-deficit/hyperactivity disorder). 2013-12-04 2023-08-12 human
Florence Cormier, Julia Muellner, Jean-Christophe Corvo. Genetics of impulse control disorders in Parkinson's disease. Journal of neural transmission (Vienna, Austria : 1996). vol 120. issue 4. 2013-10-25. PMID:23232665. recent genetic studies have investigated associations between icd and polymorphisms of genes involved in the dopamine metabolism pathway (comt, dat), dopamine receptors (drd1, drd2, drd3, drd4), serotonin receptors and its transporter (htr2a, 5htt), and glutamate receptors (grin2b). 2013-10-25 2023-08-12 Not clear
Emrah Cayla. Biochemical and genetic analyses of childhood attention deficit/hyperactivity disorder. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 159B. issue 6. 2013-04-09. PMID:22825876. to date, these studies have reported substantial evidence implicating several genes (dopaminergic: drd4, dat1, drd5, comt; noradrenergic: dbh, adra2a; serotonergic: 5-htt, htr1b, htr2a; cholinergic: chrna4, and central nervous system development pathway: snap25, bdnf) in the etiology of adhd. 2013-04-09 2023-08-12 Not clear
T Ziermans, I Dumontheil, C Roggeman, M Peyrard-Janvid, H Matsson, J Kere, T Klingber. Working memory brain activity and capacity link MAOA polymorphism to aggressive behavior during development. Translational psychiatry. vol 2. 2013-03-04. PMID:22832821. we investigated gene-brain-behavior relationships by focusing on 18 single-nucleotide polymorphisms (snps) located in six dopaminergic candidate genes (comt, slc6a3/dat1, dbh, drd4, drd5, maoa). 2013-03-04 2023-08-12 human
Lea Thaler, Patricia Groleau, Guilaine Badawi, Lindsay Sycz, Nadia Zeramdini, Andrea Too, Mimi Israel, Ridha Joober, Kenneth R Bruce, Howard Steige. Epistatic interactions implicating dopaminergic genes in bulimia nervosa (BN): relationships to eating- and personality-related psychopathology. Progress in neuro-psychopharmacology & biological psychiatry. vol 39. issue 1. 2013-01-21. PMID:22683321. we explored the influence of interactions between polymorphisms acting upon postsynaptic receptors (drd2 taqa1 rs1800497 and drd4 7r) and dopamine regulators (comt rs4680 and dat1) on the expression of eating symptoms and personality traits in women with bulimia-spectrum eating disorders. 2013-01-21 2023-08-12 Not clear
Lea Thaler, Patricia Groleau, Guilaine Badawi, Lindsay Sycz, Nadia Zeramdini, Andrea Too, Mimi Israel, Ridha Joober, Kenneth R Bruce, Howard Steige. Epistatic interactions implicating dopaminergic genes in bulimia nervosa (BN): relationships to eating- and personality-related psychopathology. Progress in neuro-psychopharmacology & biological psychiatry. vol 39. issue 1. 2013-01-21. PMID:22683321. we observed two epistatic interactions on symptom indices: interactions (in predicted directions) of drd2 by dat were seen on body mass index (p=.023), and of drd4 by comt on self-harming behaviors (p=.014)--with genetic effects that would correspond to reduced dopamine transmission coinciding with more-pathological scores. 2013-01-21 2023-08-12 Not clear