| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Banafsheh Dolatyar, Bahman Zeynali, Iman Shabani, Azita Parvaneh Tafresh. High-efficient serum-free differentiation of trabecular meshwork mesenchymal stem cells into Schwann-like cells on polylactide electrospun nanofibrous scaffolds. Neuroscience letters. 2023-08-07. PMID:37549866. |
immunostaining of tm-mscs cultured on serum-free pla nanofibrous scaffolds also showed significant expression of gap43, gfap and sox10 compared to those of control, indicating the efficient role of sfm in the differentiation of tm-mscs into scs lineage. |
2023-08-07 |
2023-08-14 |
Not clear |
| Juan Zhuang, Zheng-Jun Pan, Ying Qin, Hui Liang, Wen-Feng Zhang, Ze-Yu Sun, Han-Bo Sh. Evaluation of BDE-47-induced neurodevelopmental toxicity in zebrafish embryos. Environmental science and pollution research international. 2023-03-04. PMID:36869944. |
the results showed that bde-47 stimulated the production of dopamine and 5-hydroxytryptamine, but inhibited expression of nestin, gfap, gap43, and psd95 in 24 hpf embryos. |
2023-03-04 |
2023-08-14 |
zebrafish |
| Shukai Zheng, Qiong Zhang, Ruotong Wu, Xiaoling Shi, Jiajun Peng, Wei Tan, Wenlong Huang, Kusheng Wu, Caixia Li. Behavioral changes and transcriptomic effects at embryonic and post-embryonic stages reveal the toxic effects of 2,2',4,4'-tetrabromodiphenyl ether on neurodevelopment in zebrafish (Danio rerio). Ecotoxicology and environmental safety. vol 248. 2022-11-24. PMID:36423367. |
consistent with the locomotion and kegg results, bde-47 affected the expression of genes for central nervous system (gfap, mbpa, bdnf & pomcb), early neurogenesis (neurog1 & elavl3), and axonal development (tuba1a, tuba1b, tuba1c, syn2a, gap43 & shha). |
2022-11-24 |
2023-08-14 |
zebrafish |
| Ha-Na Oh, Donggon Yoo, Seungmin Park, Sangwoo Lee, Woo-Keun Ki. Developmental neurotoxicity induced by glutaraldehyde in neuron/astrocyte co-cultured cells and zebrafish. Ecotoxicology and environmental safety. vol 242. 2022-07-22. PMID:35868176. |
further studies showed that ga upregulated the mrna expression of the astrocyte markers gfap and s100β and downregulated the expression of the neurodevelopmental genes nestin, βiii-tubulin, gap43, and map2. |
2022-07-22 |
2023-08-14 |
human |
| Sandra S Pereira, Eliã P Botelho, Juliana G M Soares, Mariana F Farias, Ricardo Gattas. Time course of dorsolateral geniculate nucleus plasticity in adult monkeys with laser-induced retinal lesions. The Journal of comparative neurology. 2022-06-01. PMID:35650108. |
we studied changes in the expression of growth-associated protein 43 (gap43), glial fibrillary acidic protein (gfap), and calcium-binding proteins (calbindin [cb] and parvalbumin [pv]) in the dorsal lateral geniculate nucleus (dlgn) of four capuchin monkeys with laser-induced retinal lesions. |
2022-06-01 |
2023-08-13 |
monkey |
| Wei Wang, Mei-Feng Gu, Zhi-Fei Wang, Xiang-Min Shen, Jie Zhang, Liang Yan. Let-7a-5p regulated by lncRNA-MEG3 promotes functional differentiation to Schwann cells from adipose derived stem cells via directly inhibiting RBPJ-mediating Notch pathway. Apoptosis : an international journal on programmed cell death. vol 26. issue 9-10. 2021-12-01. PMID:34409556. |
let-7a-5p mimics promoted adsc differentiation into scs and up-regulated the levels of sc-related markers including s100, gfap, sox10, p75ntr, gap43, mpz, β-ngf, and ncam, while rbpj or meg3 overexpression retarded the differentiation and reduced those levels. |
2021-12-01 |
2023-08-13 |
Not clear |
| Diego Iacono, Erin K Murphy, Soundarya S Avantsa, Daniel P Perl, Regina M Da. Reduction of pTau and APP levels in mammalian brain after low-dose radiation. Scientific reports. vol 11. issue 1. 2021-09-16. PMID:33500491. |
we analyzed possible molecular and neuropathology changes of phosphorylated-tau (ptau), all-tau forms, β-tubulin, amyloid precursor protein (app), glial fibrillary acidic protein (gfap), ionized calcium binding adaptor molecule 1 (iba-1), myelin basic protein (mbp), and gap43 in frontal cortex (fc), hippocampus (h) and cerebellum (crb) of swine brains following total-body low-dose radiation (1.79 gy). |
2021-09-16 |
2023-08-13 |
Not clear |
| Nagla A El-Sherbeeny, Afaf T Ibrahiem, Howaida S Ali, Noha E Farag, Eman A Toraih, Sawsan A Zaiton. Carbamazepine conquers spinal GAP43 deficiency and sciatic Nav1.5 upregulation in diabetic mice: novel mechanisms in alleviating allodynia and hyperalgesia. Archives of pharmacal research. vol 43. issue 7. 2021-05-17. PMID:32676893. |
spinal cord of carbamazepine-treated groups had enhanced expression of gap43 but lower content of cd11b and gfap. |
2021-05-17 |
2023-08-13 |
mouse |
| Nagla A El-Sherbeeny, Afaf T Ibrahiem, Howaida S Ali, Noha E Farag, Eman A Toraih, Sawsan A Zaiton. Carbamazepine conquers spinal GAP43 deficiency and sciatic Nav1.5 upregulation in diabetic mice: novel mechanisms in alleviating allodynia and hyperalgesia. Archives of pharmacal research. vol 43. issue 7. 2021-05-17. PMID:32676893. |
the spinal cords were evaluated for synaptic plasticity (growth associated protein-43, gap43), microglia cell expression (by cd11b) and astrocyte expression (glial fibrillary acidic protein, gfap). |
2021-05-17 |
2023-08-13 |
mouse |
| Rupali Sharma, Nathan P Cramer, Bayley Perry, Zahra Adahman, Erin K Murphy, Xiufen Xu, Bernard J Dardzinski, Zygmunt Galdzicki, Daniel P Perl, Dara L Dickstein, Diego Iacon. Chronic Exposure to High Altitude: Synaptic, Astroglial and Memory Changes. Scientific reports. vol 9. issue 1. 2020-11-06. PMID:31712561. |
specifically, we found decreased levels of synaptophysin (syp) (p < 0.05) and spinophilin (sph) (p < 0.05) in the olfactory cortex, post synaptic density-95 (psd-95) (p < 0.05), growth associated protein 43 (gap43) (p < 0.05), glial fibrillary acidic protein (gfap) (p < 0.05) in the cerebellum, and syp (p < 0.05) and psd-95 (p < 0.05) in the brainstem. |
2020-11-06 |
2023-08-13 |
mouse |
| Jiri Ruzicka, Lucia Machova Urdzikova, Barbora Svobodova, Anubhav G Amin, Kristyna Karova, Jana Dubisova, Kristyna Zaviskova, Sarka Kubinova, Meic Schmidt, Meena Jhanwar-Uniyal, Pavla Jendelov. Does combined therapy of curcumin and epigallocatechin gallate have a synergistic neuroprotective effect against spinal cord injury? Neural regeneration research. vol 13. issue 1. 2020-10-01. PMID:29451216. |
quantitative polymerase chain reaction was performed to determine the relative expression of genes (sort1, fgf2, irf5, mrc1, olig2, casp3, gap43, gfap, vegf, nfκb, cntf) related to regenerative processes in injured spinal cord. |
2020-10-01 |
2023-08-13 |
rat |
| Firas M Younis, Tamar Blumenthal-Katzir, Kenneth Hollander, Nikolaos Grigoriadis, Olga Touloumi, Roza Lagoudakic, Talma Rosentha. Telmisartan-mediated metabolic profile conferred brain protection in diabetic hypertensive rats as evidenced by magnetic resonance imaging, behavioral studies and histology. European journal of pharmacology. vol 789. 2017-03-06. PMID:27417654. |
immunohistological analysis of the brain revealed significant amelioration of diabetes/hypertension-induced changes in white matter regions and microglia, evidenced by preserved myelin (lbf marker), and improved microglial neuronal markers gfap, gap43 and iba1 expression. |
2017-03-06 |
2023-08-13 |
rat |
| Philipp Janz, Robert-Benjamin Illin. A role for microglial cells in reshaping neuronal circuitry of the adult rat auditory brainstem after its sensory deafferentation. Journal of neuroscience research. vol 92. issue 4. 2014-09-23. PMID:24446187. |
by covisualizing cytological markers such as neun, gfap, cd11b, vglut-1, gad-65, and gap43 with the prominent map kinases erk1/2 and p38, we show that mapk signaling is affected by sensory deafferentation in microglia but not in astroglia or in neurons. |
2014-09-23 |
2023-08-12 |
rat |
| Oswald Steward, Kelli Sharp, Kelly Matsudaira Ye. A re-assessment of the effects of intracortical delivery of inosine on transmidline growth of corticospinal tract axons after unilateral lesions of the medullary pyramid. Experimental neurology. vol 233. issue 2. 2012-03-26. PMID:21946267. |
sections through the cervical spinal cord were stained for bda and immunostained for gap43 and gfap. |
2012-03-26 |
2023-08-12 |
rat |
| Arnab Datta, Qian Jingru, Tze Hsin Khor, Muh Tyng Teo, Klaus Heese, Siu Kwan Sz. Quantitative neuroproteomics of an in vivo rodent model of focal cerebral ischemia/reperfusion injury reveals a temporal regulation of novel pathophysiological molecular markers. Journal of proteome research. vol 10. issue 11. 2012-03-05. PMID:21950801. |
data mining revealed that (1) about 2.7% of detected proteins were temporally perturbed having an involvement in the energy metabolism (pygb, atp5b), glutamate excitotoxicity (slc1a3, glud1), neuro-inflammation (tf, c3, alb), and cerebral plasticity (gfap, vim, gap43); (2) astrocytes participated actively in the neurometabolic coupling underlining the importance of a cerebro-protective rather than a neuro-protective approach; and (3) hyper-acute yet progressive opening of the blood brain barrier (bbb), accompanied by stimulation of an innate immune response and late activation of a regenerative response, which provides an extended therapeutic window for intervention. |
2012-03-05 |
2023-08-12 |
Not clear |