| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yi Chung, Jia-Ling Wu, Wen-Ching Huan. Effects of prebiotics on intestinal physiology, neuropsychological function, and exercise capacity of mice with sleep deprivation. Food research international (Ottawa, Ont.) vol 165 issue 2023 36869551 |
results showed that sleep deprivation caused intestinal inflammation (increased tnfa and il1b) and decreased intestinal permeability with a significant decrease in the tight junction genes (ocln, cldn1, tjp1, and tjp2) of intestine and brain. |
2023-03-04 |
2023-03-06 |
mouse |
| Mikko Gynther, Mariana Leal Estrada, Sanna Loppi, Paula Korhonen, Katja M Kanninen, Tarja Malm, Jari Koistinaho, Seppo Auriola, Gert Fricker, Elena Puri. Increased Expression and Activity of Brain Cortical cPLA2 Due to Chronic Lipopolysaccharide Administration in Mouse Model of Familial Alzheimer's Disease. Pharmaceutics vol 14 issue 11 2022 36365256 |
the gene expressions of inflammation markers il1b and tnfa were significantly elevated in the cortex of both apde9 groups compared to the wild-type groups. |
2022-11-11 |
2023-01-30 |
mouse |
| Kexin Jia, Jianzhi Wu, Yijie Li, Jia Liu, Runping Liu, Yajie Cai, Yinhao Zhang, Xiaojiaoyang L. A novel pulmonary fibrosis murine model with immune-related liver injury. Animal models and experimental medicine vol issue 2022 35934841 |
this mouse model successfully recapitulated the clinical features of ae-ipf, including excessive intrapulmonary inflammation and fibrosis and extrapulmonary manifestations, as indicated by significant upregulation of il6, tnfa, il1b, tgfb, fibronectin, and col1a1 in both lungs and liver and elevated serum aspartate transaminase and alanine transaminase levels. |
2022-08-08 |
2023-01-30 |
mouse |
| Mohammad B Rashid, Mohamed A Marey, Kenji Fukuda, Shingo Haneda, Kazuya Kusama, Masayuki Shimada, Kazuhiko Imakawa, Akio Miyamot. Intrauterine infusion of low levels of interferon-tau on day-8 post-estrus stimulates the bovine endometrium to secrete apolipoprotein-A1: A possible implication for early embryo tolerance. American journal of reproductive immunology (New York, N.Y. : 1989) vol issue 2022 35785505 |
real-time pcr results revealed that ifnt-supplemented uf downregulated pro-inflammatory cytokines (tnfa, il1b) and upregulated anti-inflammatory cytokine (tgfb1) and ptges in pbmcs. |
2022-07-05 |
2023-01-27 |
cattle |
| Rohit Upadhyay, Vecihi Batuma. Aristolochic acid I induces proximal tubule injury through ROS/HMGB1/mt DNA mediated activation of TLRs. Journal of cellular and molecular medicine vol issue 2022 35765703 |
gene/ protein expression studies demonstrated activation of innate immunity (tlrs 2, 3, 4 and 9, hmgb1), inflammatory (il6, tnfa, il1b, il18, tgfb and nlrp3) and kidney injury (lcn2) markers. |
2022-06-29 |
2023-01-27 |
human |
| Ihshan Akthar, Mohamed A Marey, Yejin Kim, Masayuki Shimada, Susan S Suarez, Akio Miyamot. Sperm interaction with the uterine innate immune system: toll-like receptor 2 (TLR2) is a main sensor in cattle. Reproduction, fertility, and development vol 34 issue 2 2022 35231265 |
this acute immune response is manifested as the upregulation of mrna expression of il8, tnfa, il1b , and pges . |
2022-03-01 |
2023-01-27 |
cattle |
| Ahmed E Elweza, Mohamed A Marey, Ibrahim F Elesh, Mohammad A Zinnah, Ihshan Akthar, Chihiro Kanno, Mitsuhiro Takagi, Akio Miyamot. Zearalenone interferes with the sperm-triggered inflammation in the bovine uterus in vitro: Negative impact on sperm motility and survival. Reproductive toxicology (Elmsford, N.Y.) vol 107 issue 2021 34864119 |
pre-exposure of beecs to zen, amplified the sperm-triggered upregulation of pro-inflammatory cytokines (tnfa and il1b) and chemokine il8 mrna abundance in beecs. |
2021-12-10 |
2023-01-26 |
cattle |
| Hong Li, J Alyce Bradbury, Matthew L Edin, Joan P Graves, Artiom Gruzdev, Jennifer Cheng, Samantha L Hoopes, Laura M DeGraff, Michael B Fessler, Stavros Garantziotis, Shepherd H Schurman, Darryl C Zeldi. sEH promotes macrophage phagocytosis and lung clearance of Streptococcus pneumoniae. The Journal of clinical investigation vol 131 issue 22 2021 34591792 |
ephx2-/- mice had normal lung il1b, il6, and tnfa expression levels and macrophage recruitment to the lungs during s. pneumoniae infection; however, ephx2 disruption attenuated proinflammatory cytokine induction, tlr2 and pgylrp1 receptor upregulation, and ras-related c3 botulinum toxin substrates 1 and 2 (rac1/2) and cell division control protein 42 homolog (cdc42) activation in pgn-stimulated macrophages. |
2021-12-07 |
2023-01-26 |
mouse |
| Tim Schauer, Anne-Sophie Mazzoni, Anna Henriksson, Ingrid Demmelmaier, Sveinung Berntsen, Truls Raastad, Karin Nordin, Bente K Pedersen, Jesper F Christense. Exercise intensity and markers of inflammation during and after (neo-) adjuvant cancer treatment. Endocrine-related cancer vol 28 issue 3 2021 33608485 |
plasma taken at baseline, immediately post-treatment and post-intervention was analyzed for levels of interleukin 1 beta (il1b), il6, il8, il10, tumor-necrosis factor alpha (tnfa) and c-reactive protein (crp). |
2021-12-03 |
2023-01-26 |
human |
| Tim Schauer, Anne-Sophie Mazzoni, Anna Henriksson, Ingrid Demmelmaier, Sveinung Berntsen, Truls Raastad, Karin Nordin, Bente K Pedersen, Jesper F Christense. Exercise intensity and markers of inflammation during and after (neo-) adjuvant cancer treatment. Endocrine-related cancer vol 28 issue 3 2021 33608485 |
regardless of exercise intensity, significant increases of il6, il8, il10 and tnfa post-treatment followed by significant declines, except for il8, until post-intervention were observed with no difference for crp or il1b. |
2021-12-03 |
2023-01-26 |
human |
| Jose Carlos Campos-S\\xc3\\xa1nchez, Javier Mayor-Lafuente, Daniel Gonz\\xc3\\xa1lez-Silvera, Francisco A Guardiola, Mar\\xc3\\xada \\xc3\\x81ngeles Esteba. Acute inflammatory response in the skin of gilthead seabream (Sparus aurata) caused by carrageenin. Fish & shellfish immunology vol 119 issue 2021 34656758 |
the gene expression of inflammatory markers (csfr1, mhc-ii and phox40), several pro-inflammatory cytokines (il1b, tnfa, il6, il8 and il18) and other molecules related (such as myd88 and c-rel) were up-regulated at 1.5 and 3\xc2\xa0h in fish injected with carrageenin compared with control levels. |
2021-11-26 |
2023-01-26 |
Not clear |
| Maryam Akhtari, Seyed Jalal Zargar, Mahdi Vojdanian, Ahmadreza Jamshidi, Mahdi Mahmoud. Monocyte-derived and M1 macrophages from ankylosing spondylitis patients released higher TNF-\\xce\\xb1 and expressed more IL1B in response to BzATP than macrophages from healthy subjects. Scientific reports vol 11 issue 1 2021 34497300 |
besides, bzatp treatment significantly upregulated il1b expression, reduced tnfa and il23a expression, and tnf-\xce\xb1 release in m1 macrophages from both groups. |
2021-11-11 |
2023-01-26 |
human |
| E M Donnellan, M B O'Brien, K G Meade, S Fai. Comparison of the uterine inflammatory response to frozen-thawed sperm from high and low fertility bulls. Theriogenology vol 176 issue 2021 34564014 |
inflammatory gene expression of il1a, il1b, il6, tnfa and cxcl8 were assessed by qpcr and il1-\xce\xb2 and il-8 were quantified in explant supernatants by elisa. |
2021-11-04 |
2023-01-26 |
Not clear |
| E M Donnellan, M B O'Brien, K G Meade, S Fai. Comparison of the uterine inflammatory response to frozen-thawed sperm from high and low fertility bulls. Theriogenology vol 176 issue 2021 34564014 |
there was a significant up-regulation of il1a, il1b and tnfa from frozen-thawed sperm, irrespective of fertility status, compared to the unstimulated control. |
2021-11-04 |
2023-01-26 |
Not clear |
| Wiktoria Ratajczak, Sarah D Atkinson, Catriona Kell. A20 controls expression of beta-cell regulatory genes and transcription factors. Journal of molecular endocrinology vol 67 issue 4 2021 34463643 |
glucose-stimulated insulin secretion and production of inflammatory cytokines (tnfa, il1b and ifng) were measured by elisa. |
2021-10-19 |
2023-01-26 |
human |
| Wiktoria Ratajczak, Sarah D Atkinson, Catriona Kell. A20 controls expression of beta-cell regulatory genes and transcription factors. Journal of molecular endocrinology vol 67 issue 4 2021 34463643 |
tnfa, il1b and ifng were elevated in a20 deficient cells and found to independently elicit changes in gene expression. |
2021-10-19 |
2023-01-26 |
human |
| Umesh K Shandilya, A Sharma, S Mallikarjunappa, J Guo, Y Mao, K G Meade, N A Karro. CRISPR-Cas9-mediated knockout of TLR4 modulates Mycobacterium avium ssp. paratuberculosis cell lysate-induced inflammation in bovine mammary epithelial cells. Journal of dairy science vol 104 issue 10 2021 34253365 |
however, in response to lps, the ko cells showed reduced expression of key inflammatory genes (tnfa, il1a, il1b, and il6) and supernatant cytokine levels (tnf-\xce\xb1, il-6, ccl2, il-8) as compared with unedited cells. |
2021-09-23 |
2023-01-26 |
cattle |
| Marie Vandestienne, Yujiao Zhang, Icia Santos-Zas, Rida Al-Rifai, Jeremie Joffre, Andreas Giraud, Ludivine Laurans, Bruno Esposito, Florence Pinet, Patrick Bruneval, Juliette Raffort, Fabien Lareyre, Jose Vilar, Amir Boufenzer, Lea Guyonnet, Coralie Guerin, Eric Clauser, Jean-S\\xc3\\xa9bastien Silvestre, Sylvie Lang, Laurie Soulat-Dufour, Alain Tedgui, Ziad Mallat, Soraya Taleb, Alexandre Boissonnas, Marc Derive, Giulia Chinetti, Hafid Ait-Oufell. TREM-1 orchestrates angiotensin II-induced monocyte trafficking and promotes experimental abdominal aortic aneurysm. The Journal of clinical investigation vol 131 issue 2 2021 33258804 |
trem1 gene deletion attenuated the inflammatory response in the aorta, with a reduction of il1b, tnfa, mmp2, and mmp9 mrna expression, and led to a decreased macrophage content due to a reduction of ly6chi classical monocyte trafficking. |
2021-09-09 |
2023-01-26 |
human |
| Joo Jie Ching, Adawiyah Suriza Shuib, Noorlidah Abdullah, Nazia Abdul Majid, Norhidayah Mohd Taufek, Jumria Sutra, Mohammad Noor Amal Azma. Hot water extract of Pleurotus pulmonarius stalk waste enhances innate immune response and immune-related gene expression in red hybrid tilapia Oreochromis sp. following challenge with pathogen-associated molecular patterns. Fish & shellfish immunology vol 116 issue 2021 34157396 |
hwe-supplemented diet also resulted in higher mrna transcription of il1b and tnfa in midgut, spleen and head kidney at 1-day post pamps injection. |
2021-08-26 |
2023-01-26 |
Not clear |
| Masayuki Miyagi, Kentaro Uchida, Shotaro Takano, Mitsufumi Nakawaki, Hiroyuki Sekiguchi, Toshiyuki Nakazawa, Takayuki Imura, Wataru Saito, Eiki Shirasawa, Ayumu Kawakubo, Tsutomu Akazawa, Gen Inoue, Masashi Takas. Role of CD14-positive cells in inflammatory cytokine and pain-related molecule expression in human degenerated intervertebral discs. Journal of orthopaedic research : official publication of the Orthopaedic Research Society vol 39 issue 8 2021 32856747 |
inflammatory cytokines messenger rna (mrna) in the cd14(+) and cd14(-) cells, including tumor necrosis factor \xc9\x91 (tnfa), in, terleukin-1\xce\xb2 (il1b) and il6, were determined using quantitative polymerase chain reaction (qpcr) and their expression levels were compared. |
2021-08-09 |
2023-01-26 |
mouse |