| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hideki Sakatani, Masamitsu Kono, Tatsuya Shiga, Hiroki Kuwazoe, Denisa Nanushaj, Ibu Matsuzaki, Shin-Ichi Murata, Masayasu Miyajima, Yuka Okada, Shizuya Saika, Muneki Hotom. The Roles of Transient Receptor Potential Vanilloid 1 and 4 in Olfactory Regeneration. Laboratory investigation; a journal of technical methods and pathology vol 103 issue 4 2023 36870285 |
trpv1 knockout (ko), trpv4 ko, and wild-type (wt) mice were used to model methimazole-induced olfactory dysfunction. |
2023-03-04 |
2023-03-06 |
mouse |
| Hideki Sakatani, Masamitsu Kono, Tatsuya Shiga, Hiroki Kuwazoe, Denisa Nanushaj, Ibu Matsuzaki, Shin-Ichi Murata, Masayasu Miyajima, Yuka Okada, Shizuya Saika, Muneki Hotom. The Roles of Transient Receptor Potential Vanilloid 1 and 4 in Olfactory Regeneration. Laboratory investigation; a journal of technical methods and pathology vol 103 issue 4 2023 36870285 |
the proliferation of orn progenitor cells was reduced in trpv1 ko mice, which delayed orn regeneration and the improvement of olfactory behavior. |
2023-03-04 |
2023-03-06 |
mouse |
| Roberto Rodr\\xc3\\xadguez-Morales, Viveca V\\xc3\\xa9lez-Negr\\xc3\\xb3n, Aranza Torrado-Tapias, Gaurav Varshney, Martine Behr. Expression patterns of activating transcription factor 5 (atf5a and atf5b) in zebrafish. Gene expression patterns : GEP vol 37 issue 2021 32663618 |
atf5 is strongly expressed in the rodent nose and mice knockout (ko) pups have defective olfactory sensory neurons (osns), smaller olfactory bulbs (ob), while adults are smell deficient. |
2021-07-19 |
2023-01-26 |
mouse |
| Ching-San Tseng, Shen-Ju Chou, Yi-Shuian Huan. CPEB4-Dependent Neonate-Born Granule Cells Are Required for Olfactory Discrimination. Frontiers in behavioral neuroscience vol 13 issue 2020 30728769 |
our previous study demonstrated that the translational regulator, cytoplasmic polyadenylation element-binding protein 4 (cpeb4), is a survival factor exclusively for neonate-born but not svz/adult-derived gcs, so cpeb4-knockout (ko) mice provide unique leverage to study early postnatal-born gc-regulated olfactory functions. |
2020-09-30 |
2023-01-26 |
mouse |
| Lamees Alhassen, Alvin Phan, Wedad Alhassen, Paul Nguyen, Alice Lo, Hanan Shaharuddin, Nayna Sanathara, Olivier Civelli, Amal Alachka. The role of Olfaction in MCH-regulated spontaneous maternal responses. Brain research vol 1719 issue 2020 31121161 |
strikingly, however, we found that while mchr1 ko mice were unable to detect pups' chemosensory signals and displayed impairment in general olfactory discrimination, mch cko mice exhibited normal olfactory function. |
2020-09-25 |
2023-01-26 |
mouse |
| Liangcai Gao, Zejie Lin, Wenhao Hu, Chi Liu, Tian Zhou, Guixiang Xie, Min Qian, Bing N. Age-specific effects of P2X7 receptors on olfactory function in mice. Neuroreport vol 30 issue 16 2020 31425346 |
the results indicated that middle and old-aged p2x7r ko mice showed better olfactory function than middle and old-aged wt mice. |
2020-07-14 |
2023-01-26 |
mouse |
| Liangcai Gao, Zejie Lin, Wenhao Hu, Chi Liu, Tian Zhou, Guixiang Xie, Min Qian, Bing N. Age-specific effects of P2X7 receptors on olfactory function in mice. Neuroreport vol 30 issue 16 2020 31425346 |
however, worse olfactory function was observed in young-aged p2x7r ko mice compared with young-aged wt mice. |
2020-07-14 |
2023-01-26 |
mouse |
| Liangcai Gao, Zejie Lin, Wenhao Hu, Chi Liu, Tian Zhou, Guixiang Xie, Min Qian, Bing N. Age-specific effects of P2X7 receptors on olfactory function in mice. Neuroreport vol 30 issue 16 2020 31425346 |
in this study, we analyzed olfactory functions of 2-month-old, 10-month-old and 18-month-old female p2x7r ko mice and age-matched female c57bl/6 wildtype mice (wt mice) by buried food seeking test and olfactory avoidance test. |
2020-07-14 |
2023-01-26 |
mouse |
| Heidi Hsieh, Michael C Horwath, Mary Beth Gente. Zinc gluconate toxicity in wild-type vs. MT1/2-deficient mice. Neurotoxicology vol 58 issue 2017 27979773 |
in vivo studies using wild-type, mt1/2 knockout mice (mt ko), and heterozygotes administered zg by in instillation showed profound loss of the olfactory mucosa in the nasal cavity. |
2017-11-24 |
2023-01-26 |
mouse |
| Gianluca Pietra, Michele Dibattista, Anna Menini, Johannes Reisert, Anna Boccacci. The Ca2+-activated Cl- channel TMEM16B regulates action potential firing and axonal targeting in olfactory sensory neurons. The Journal of general physiology vol 148 issue 4 2017 27619419 |
suction electrode recordings from isolated olfactory neurons and on-cell loose-patch recordings from dendritic knobs of neurons in the olfactory epithelium show that randomly selected neurons from tmem16b ko mice respond to stimulation with increased firing activity than those from wild-type (wt) mice. |
2017-11-22 |
2023-01-25 |
mouse |
| Jin Hwan Lee, Ling Wei, Todd C Deveau, Xiaohuan Gu, Shan Ping Y. Expression of the NMDA receptor subunit GluN3A (NR3A) in the olfactory system and its regulatory role on olfaction in the adult mouse. Brain structure & function vol 221 issue 6 2017 26334321 |
a butyl alcohol stimulus increased immediate-early gene c-fos expression in the olfactory system of wt mice, while this response was absent in glun3a ko mice. |
2017-09-28 |
2023-01-25 |
mouse |
| Jin Hwan Lee, Ling Wei, Todd C Deveau, Xiaohuan Gu, Shan Ping Y. Expression of the NMDA receptor subunit GluN3A (NR3A) in the olfactory system and its regulatory role on olfaction in the adult mouse. Brain structure & function vol 221 issue 6 2017 26334321 |
in littermate glun3a knockout (glun3a(-/-); ko) mice, the expression of olfactory marker protein normally found in mature olfactory sensory neurons was significantly reduced in the olfactory bulb and epithelium. |
2017-09-28 |
2023-01-25 |
mouse |
| Nelly Redolfi, Luisa Galla, Andrea Maset, Luca Murru, Eleonora Savoia, Ilaria Zamparo, Angela Gritti, Pierre Billuart, Maria Passafaro, Claudia Lodovich. Oligophrenin-1 regulates number, morphology and synaptic properties of adult-born inhibitory interneurons in the olfactory bulb. Human molecular genetics vol 25 issue 23 2017 27742778 |
furthermore, we found that olfactory behaviour was perturbed in ophn1 ko mice. |
2017-07-24 |
2023-01-26 |
mouse |
| Hideko Yamamoto, Etsuko Kamegaya, Yoko Hagino, Yukio Takamatsu, Wakako Sawada, Maaya Matsuzawa, Soichiro Ide, Toshifumi Yamamoto, Masayoshi Mishina, Kazutaka Iked. Loss of GluN2D subunit results in social recognition deficit, social stress, 5-HT Neuropharmacology vol 112 issue Pt A 2017 27480795 |
despite apparently normal olfactory function and social interaction, glun2d ko mice exhibited a decrease in preference for social novelty, suggesting a deficit in social recognition or memory. |
2017-07-11 |
2023-01-25 |
mouse |
| Hiroo Takahashi, Yoichi Ogawa, Sei-Ichi Yoshihara, Ryo Asahina, Masahito Kinoshita, Tatsuro Kitano, Michiko Kitsuki, Kana Tatsumi, Mamiko Okuda, Kouko Tatsumi, Akio Wanaka, Hirokazu Hirai, Peter L Stern, Akio Tsubo. A Subtype of Olfactory Bulb Interneurons Is Required for Odor Detection and Discrimination Behaviors. The Journal of neuroscience : the official journal of the Society for Neuroscience vol 36 issue 31 2017 27488640 |
remarkably, in olfactory behavior tests, 5t4 ko mice had higher odor detection thresholds than the wt, as well as defects in odor discrimination learning. |
2017-07-10 |
2023-01-25 |
mouse |
| Erica L Schoeller, Daniel D Clark, Sandeepa Dey, Nathan V Cao, Sheila J Semaan, Ling W Chao, Alexander S Kauffman, Lisa Stowers, Pamela L Mello. Bmal1 Is Required for Normal Reproductive Behaviors in Male Mice. Endocrinology vol 157 issue 12 2017 27704948 |
we determined that bmal1 ko males also fail to display aggression and avoidance of predator scent, despite intact main olfactory function. |
2017-05-26 |
2023-01-26 |
mouse |
| Miwako Masugi-Tokita, Peter J Flor, Mitsuhiro Kawat. Metabotropic Glutamate Receptor Subtype 7 in the Bed Nucleus of the Stria Terminalis is Essential for Intermale Aggression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology vol 41 issue 3 2016 26149357 |
to clarify the olfactory deficit, we then exposed mice to urine and analyzed c-fos-immunoreactivity, discovering a remarkable reduction in neural activity in the bed nucleus of the stria terminalis (bnst) of mglur7 ko mice. |
2016-10-06 |
2023-01-25 |
mouse |
| Hannah Kim, Yunjin Lee, Ji-Eun Kim, Pyung-Lim Ha. Reversal of an Unconditioned Behavioral Preference for Specific Food Pellets by Intervention of Whisker Sensory Inputs. Experimental neurobiology vol 25 issue 2 2016 27122994 |
recently, we reported that ac5 knockout (ko) mice preferred food pellets carrying an olfactory cue produced by ac5 ko mice during food consumption (ac5 ko pellets) over food pellets that had been taken by wildtype (wt) mice. |
2016-04-28 |
2023-01-25 |
mouse |
| K Marquardt, M Saha, M Mishina, J W Young, J L Brigma. Loss of GluN2A-containing NMDA receptors impairs extra-dimensional set-shifting. Genes, brain, and behavior vol 13 issue 7 2015 25059550 |
glun2a(ko) were not impaired on discrimination or reversal problems when tactile or olfactory stimuli were used, or when visual stimuli were sufficiently easy to discriminate. |
2015-05-22 |
2023-01-25 |
mouse |
| Alicia L Degano, Min Jung Park, Judith Penati, Qun Li, Gabriele V Ronnet. MeCP2 is required for activity-dependent refinement of olfactory circuits. Molecular and cellular neurosciences vol 59 issue 2014 24472844 |
our results reveal defective postnatal refinement of olfactory circuits in mecp2 knock out (ko) mice after sensory (odorant) stimulation. |
2014-12-14 |
2023-01-25 |
mouse |