| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hideki Sakatani, Masamitsu Kono, Tatsuya Shiga, Hiroki Kuwazoe, Denisa Nanushaj, Ibu Matsuzaki, Shin-Ichi Murata, Masayasu Miyajima, Yuka Okada, Shizuya Saika, Muneki Hotom. The Roles of Transient Receptor Potential Vanilloid 1 and 4 in Olfactory Regeneration. Laboratory investigation; a journal of technical methods and pathology vol 103 issue 4 2023 36870285 |
trpv1 knockout (ko), trpv4 ko, and wild-type (wt) mice were used to model methimazole-induced olfactory dysfunction. |
2023-03-04 |
2023-03-06 |
mouse |
| Hideki Sakatani, Masamitsu Kono, Tatsuya Shiga, Hiroki Kuwazoe, Denisa Nanushaj, Ibu Matsuzaki, Shin-Ichi Murata, Masayasu Miyajima, Yuka Okada, Shizuya Saika, Muneki Hotom. The Roles of Transient Receptor Potential Vanilloid 1 and 4 in Olfactory Regeneration. Laboratory investigation; a journal of technical methods and pathology vol 103 issue 4 2023 36870285 |
the proliferation of orn progenitor cells was reduced in trpv1 ko mice, which delayed orn regeneration and the improvement of olfactory behavior. |
2023-03-04 |
2023-03-06 |
mouse |
| Ling Chen, Qiguo Hu, Huaicun Liu, Yan Zhao, Sun-On Chan, Jun Wan. Nogo-A Induced Polymerization of Microtubule Is Involved in the Inflammatory Heat Hyperalgesia in Rat Dorsal Root Ganglion Neurons. International journal of molecular sciences vol 22 issue 19 2021 34638704 |
the colocalization of acetylated \xce\xb1-tubulin and trpv1 in drg neurons was also reduced dramatically in nogo-a ko rats under inflammatory pain. |
2021-10-26 |
2023-01-26 |
rat |
| Ling Chen, Qiguo Hu, Huaicun Liu, Yan Zhao, Sun-On Chan, Jun Wan. Nogo-A Induced Polymerization of Microtubule Is Involved in the Inflammatory Heat Hyperalgesia in Rat Dorsal Root Ganglion Neurons. International journal of molecular sciences vol 22 issue 19 2021 34638704 |
moreover, the down-regulation of trpv1 in drg of nogo-a ko rats after injection of cfa was reversed by intrathecal injection of paclitaxel, a microtubule stabilizer. |
2021-10-26 |
2023-01-26 |
rat |
| Cody W Kowalski, Forrest J Ragozzino, Jonathan E M Lindberg, BreeAnne Peterson, Janelle M Lugo, Ryan J McLaughlin, James H Peter. Cannabidiol activation of vagal afferent neurons requires TRPA1. Journal of neurophysiology vol 124 issue 5 2021 32965166 |
these pharmacological experiments were confirmed using genetic knockouts where trpa1 ko mice lacked cbd responses, whereas trpv1 knockout (ko) mice exhibited cbd-induced activation. |
2021-10-07 |
2023-01-26 |
mouse |
| Taylor Follansbee, Yan Zhou, Xuesong Wu, Jeremy Delahanty, Amanda Nguyen, Dan Domocos, Mirela Iodi Carstens, Samuel T Hwang, Earl Carsten. Signs of chronic itch in the mouse imiquimod model of psoriasiform dermatitis: sex differences and roles of TRPV1 and TRPA1. Itch (Philadelphia, Pa.) vol 4 issue 3 2021 34164579 |
trpv1 and trpa1 knockout (ko) mice all exhibited numeric increases in spontaneous scratching which were significant for trpv1ko mice and trpa1ko males. |
2021-06-26 |
2023-01-26 |
mouse |
| Xu Liu, Jiang-Tao Zhang, Yue Hu, Wen-Qi Shan, Zhi-Hong Wang, Qing-Yue Fu, Dan-Ni Fu, Jiang Ji, Tong Li. Formalin Itch Test: Low-Dose Formalin Induces Histamine-Independent, TRPA1-Mediated Itch in Mice. Frontiers in medicine vol 8 issue 2021 33681255 |
further, we found that 0.3% formalin-induced scratching was histamine-independent and significantly attenuated by transient receptor potential ion channel a1 (trpa1) inhibitor (hc030031) or in trpa1 knockout (ko) mice, but not affected by transient receptor potential ion channel v1 (trpv1) inhibitor (capsazepine) or in trpv1 ko mice. |
2021-03-10 |
2023-01-26 |
rat |
| Park Yonghak, Seiji Miyata, Erkin Kurgano. TRPV1 is crucial for thermal homeostasis in the mouse by heat loss behaviors under warm ambient temperature. Scientific reports vol 10 issue 1 2020 32472067 |
trpv1 ko mice exhibited prolonged and prominent hyperthermia upon exposure to 35.0\xe2\x80\x89\xc2\xb0c, whereas wt mice showed transient hyperthermia. |
2020-12-04 |
2023-01-26 |
mouse |
| H Inagaki, E Kurganov, Y Park, E Furube, S Miyat. Oral gavage of capsaicin causes TRPV1-dependent acute hypothermia and TRPV1-independent long-lasting increase of locomotor activity in the mouse. Physiology & behavior vol 206 issue 2020 31009639 |
oral gavage of cap acutely decreased core body temperature and alternatively increased tail surface temperature of wild type (wt) mice, whereas such acute temperature changes were not observed in trpv1 knockout (ko) animals. |
2020-07-02 |
2023-01-26 |
mouse |
| H Inagaki, E Kurganov, Y Park, E Furube, S Miyat. Oral gavage of capsaicin causes TRPV1-dependent acute hypothermia and TRPV1-independent long-lasting increase of locomotor activity in the mouse. Physiology & behavior vol 206 issue 2020 31009639 |
moreover, a long-lasting increase of locomotor activity was observed in both wt and trpv1 ko mice after oral gavage of cap, but increase in core body temperature was seen only in trpv1 ko animals. |
2020-07-02 |
2023-01-26 |
mouse |
| H Inagaki, E Kurganov, Y Park, E Furube, S Miyat. Oral gavage of capsaicin causes TRPV1-dependent acute hypothermia and TRPV1-independent long-lasting increase of locomotor activity in the mouse. Physiology & behavior vol 206 issue 2020 31009639 |
oral gavage of cap induced neuronal fos expression in the circumventricular organs, median and medial preoptic area, arcuate nucleus, and nucleus of the solitary tract, whereas neuronal fos expression was scarcely observed in trpv1 ko mice. |
2020-07-02 |
2023-01-26 |
mouse |
| Consuelo Amantini, Valerio Farfariello, Claudio Cardinali, Maria Beatrice Morelli, Oliviero Marinelli, Massimo Nabissi, Matteo Santoni, Laura Bonfili, Valentina Cecarini, Anna Maria Eleuteri, Giorgio Santon. The TRPV1 ion channel regulates thymocyte differentiation by modulating autophagy and proteasome activity. Oncotarget vol 8 issue 53 2019 29207602 |
thymocytes from trpv1 ko mice display both autophagy and proteasome dysfunctions, resulting in increased apoptotic cells and reduced total dp thymocyte number. |
2019-11-20 |
2023-01-26 |
mouse |
| Consuelo Amantini, Valerio Farfariello, Claudio Cardinali, Maria Beatrice Morelli, Oliviero Marinelli, Massimo Nabissi, Matteo Santoni, Laura Bonfili, Valentina Cecarini, Anna Maria Eleuteri, Giorgio Santon. The TRPV1 ion channel regulates thymocyte differentiation by modulating autophagy and proteasome activity. Oncotarget vol 8 issue 53 2019 29207602 |
in addition, positive selection of thymocytes triggered by anti-tcr\xce\xb2/cd2 ab-mediated costimulation induces apoptosis in thymocytes from trpv1 ko as compared with wt mice. |
2019-11-20 |
2023-01-26 |
mouse |
| Takuya Kameda, Joel Zvick, Miriam Vuk, Aleksandra Sadowska, Wai Kit Tam, Victor Y Leung, Kata B\\xc3\\xb6lcskei, Zsuzsanna Helyes, Lee Ann Applegate, Oliver N Hausmann, Juergen Klasen, Olga Krupkova, Karin Wuertz-Koza. Expression and Activity of TRPA1 and TRPV1 in the Intervertebral Disc: Association with Inflammation and Matrix Remodeling. International journal of molecular sciences vol 20 issue 7 2019 30974795 |
the matrix structure and composition in caudal motion segments from trpa1 and trpv1 wild-type (wt) and knock-out (ko) mice was visualized by fast staining. |
2019-07-30 |
2023-01-26 |
mouse |
| Takuya Kameda, Joel Zvick, Miriam Vuk, Aleksandra Sadowska, Wai Kit Tam, Victor Y Leung, Kata B\\xc3\\xb6lcskei, Zsuzsanna Helyes, Lee Ann Applegate, Oliver N Hausmann, Juergen Klasen, Olga Krupkova, Karin Wuertz-Koza. Expression and Activity of TRPA1 and TRPV1 in the Intervertebral Disc: Association with Inflammation and Matrix Remodeling. International journal of molecular sciences vol 20 issue 7 2019 30974795 |
trpa1 ko in mice was associated with signs of degeneration in the nucleus pulposus and the vertebral growth plate, whereas trpv1 ko did not show profound changes. |
2019-07-30 |
2023-01-26 |
mouse |
| Jae Hoon Jeong, Dong Kun Lee, Shun-Mei Liu, Streamson C Chua, Gary J Schwartz, Young-Hwan J. Activation of temperature-sensitive TRPV1-like receptors in ARC POMC neurons reduces food intake. PLoS biology vol 16 issue 4 2019 29689050 |
to show expression of trpv1-like receptors in arc pomc neurons, we use single-cell reverse transcription-polymerase chain reaction (rt-pcr), immunohistochemistry, electrophysiology, trpv1 knock-out (ko), and trpv1-cre knock-in mice. |
2019-03-27 |
2023-01-26 |
mouse |
| N I Yarushkina, M N Sudalina, Y M Punin, L P Filaretov. Vulnerability of gastric and small intestinal mucosa to ulcerogenic action of indomethacin in C57/BL6/J mice and transient receptor potential channel vanilloid type 1 knockout mice. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society vol 69 issue 6 2019 30802217 |
although im-induced gastrointestinal injury was detectable in both c57/bl6/j and trpv1 ko mice, area of gastric damage was greater in c57/bl6/j than in trpv1 ko mice, whereas the small intestinal injury (48 and 72 h after im injection), on the contrary, prevailed in trpv1 ko mice compared to c57/bl6/j mice. |
2019-03-15 |
2023-01-26 |
mouse |
| N I Yarushkina, M N Sudalina, Y M Punin, L P Filaretov. Vulnerability of gastric and small intestinal mucosa to ulcerogenic action of indomethacin in C57/BL6/J mice and transient receptor potential channel vanilloid type 1 knockout mice. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society vol 69 issue 6 2019 30802217 |
in 24 h after im injection, the total area of intestinal injury did not differ in c57bl6/j and trpv1 ko mice, however histological score was higher in trpv1 ko mice than c57bl6/j mice. |
2019-03-15 |
2023-01-26 |
mouse |
| N I Yarushkina, M N Sudalina, Y M Punin, L P Filaretov. Vulnerability of gastric and small intestinal mucosa to ulcerogenic action of indomethacin in C57/BL6/J mice and transient receptor potential channel vanilloid type 1 knockout mice. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society vol 69 issue 6 2019 30802217 |
trpv1 ko mice showed the increased tail flick latencies and the lacking im-induced corticosterone rise. |
2019-03-15 |
2023-01-26 |
mouse |
| Lukas Hofmann, Dorothea Hose, Anne Grie\\xc3\\x9fhammer, Robert Blum, Frank D\\xc3\\xb6ring, Sulayman Dib-Hajj, Stephen Waxman, Claudia Sommer, Erhard Wischmeyer, Nurcan \\xc3\\x9c\\xc3\\xa7eyle. Characterization of small fiber pathology in a mouse model of Fabry disease. eLife vol 7 issue 2019 30328411 |
old gla ko mice show increased trpv1 protein in drg neurons and heat hypersensitivity upon i.pl. |
2019-03-11 |
2023-01-26 |
mouse |