All Relations between ko and trpv1

Publication Sentence Publish Date Extraction Date Species
Rachel A Arnold, Daniel K Fowler, James Henry Peter. TRPV1 ENHANCES CHOLECYSTOKININ SIGNALING IN PRIMARY VAGAL AFFERENT NEURONS AND MEDIATES THE CENTRAL EFFECTS ON SPONTANEOUS GLUTAMATE RELEASE IN THE NTS. American journal of physiology. Cell physiology. 2023-12-04. PMID:38047304. while competitive antagonism of trpv1 failed to alter cck1r signaling, trpv1 pore blockade or genetic deletion (trpv1 ko) significantly reduced the cck response in cultured vagal afferents and eliminated its ability to increase spontaneous glutamate release in the nts. 2023-12-04 2023-12-10 Not clear
Melinda Boros, Noémi Sóki, Abigél Molnár, Hajnalka Ábrahá. Morphological study of the postnatal hippocampal development in the TRPV1 knockout mice. Temperature (Austin, Tex.). vol 10. issue 1. 2023-05-15. PMID:37187833. trpv1 links to fever, while, according to previous studies on trpv1 knock-out (ko) mice, the role of the channel in the generation of febrile seizure is debated. 2023-05-15 2023-08-14 mouse
Melinda Boros, Noémi Sóki, Abigél Molnár, Hajnalka Ábrahá. Morphological study of the postnatal hippocampal development in the TRPV1 knockout mice. Temperature (Austin, Tex.). vol 10. issue 1. 2023-05-15. PMID:37187833. despite the developmental aspects of febrile seizure as well as of cajal-retzius cells, no information is available about the hippocampal development in trpv1 ko mouse. 2023-05-15 2023-08-14 mouse
Melinda Boros, Noémi Sóki, Abigél Molnár, Hajnalka Ábrahá. Morphological study of the postnatal hippocampal development in the TRPV1 knockout mice. Temperature (Austin, Tex.). vol 10. issue 1. 2023-05-15. PMID:37187833. therefore, in the present work postnatal development of the hippocampal formation was studied in trpv1 ko mice. 2023-05-15 2023-08-14 mouse
Melinda Boros, Noémi Sóki, Abigél Molnár, Hajnalka Ábrahá. Morphological study of the postnatal hippocampal development in the TRPV1 knockout mice. Temperature (Austin, Tex.). vol 10. issue 1. 2023-05-15. PMID:37187833. however, the fact that the hippocampus of ko mice lacks major developmental abnormalities supports the use of trpv1 ko in various animal models of diseases and pathological conditions. 2023-05-15 2023-08-14 mouse
Yan Yang, Yulin Sun, Chan Zhu, Xinyu Shen, Jianmei Sun, Tao Jing, Shi Jun, Changming Wang, Guang Yu, Xinzhong Dong, Meixiao Sheng, Zongxiang Tan. Allantoin induces pruritus by activating MrgprD in chronic kidney disease. Journal of cellular physiology. 2023-03-07. PMID:36879552. the calcium influx and action potential reduced significantly in drg neurons of mrgprd ko or trpv1 ko mice. 2023-03-07 2023-08-14 mouse
Hideki Sakatani, Masamitsu Kono, Tatsuya Shiga, Hiroki Kuwazoe, Denisa Nanushaj, Ibu Matsuzaki, Shin-Ichi Murata, Masayasu Miyajima, Yuka Okada, Shizuya Saika, Muneki Hotom. The Roles of Transient Receptor Potential Vanilloid 1 and 4 in Olfactory Regeneration. Laboratory investigation; a journal of technical methods and pathology. vol 103. issue 4. 2023-03-04. PMID:36870285. trpv1 knockout (ko), trpv4 ko, and wild-type (wt) mice were used to model methimazole-induced olfactory dysfunction. 2023-03-04 2023-08-14 mouse
Hideki Sakatani, Masamitsu Kono, Tatsuya Shiga, Hiroki Kuwazoe, Denisa Nanushaj, Ibu Matsuzaki, Shin-Ichi Murata, Masayasu Miyajima, Yuka Okada, Shizuya Saika, Muneki Hotom. The Roles of Transient Receptor Potential Vanilloid 1 and 4 in Olfactory Regeneration. Laboratory investigation; a journal of technical methods and pathology. vol 103. issue 4. 2023-03-04. PMID:36870285. the proliferation of orn progenitor cells was reduced in trpv1 ko mice, which delayed orn regeneration and the improvement of olfactory behavior. 2023-03-04 2023-08-14 mouse
Ling Chen, Qiguo Hu, Huaicun Liu, Yan Zhao, Sun-On Chan, Jun Wan. Nogo-A Induced Polymerization of Microtubule Is Involved in the Inflammatory Heat Hyperalgesia in Rat Dorsal Root Ganglion Neurons. International journal of molecular sciences. vol 22. issue 19. 2021-10-26. PMID:34638704. the colocalization of acetylated α-tubulin and trpv1 in drg neurons was also reduced dramatically in nogo-a ko rats under inflammatory pain. 2021-10-26 2023-08-13 rat
Ling Chen, Qiguo Hu, Huaicun Liu, Yan Zhao, Sun-On Chan, Jun Wan. Nogo-A Induced Polymerization of Microtubule Is Involved in the Inflammatory Heat Hyperalgesia in Rat Dorsal Root Ganglion Neurons. International journal of molecular sciences. vol 22. issue 19. 2021-10-26. PMID:34638704. moreover, the down-regulation of trpv1 in drg of nogo-a ko rats after injection of cfa was reversed by intrathecal injection of paclitaxel, a microtubule stabilizer. 2021-10-26 2023-08-13 rat
Xu Liu, Jiang-Tao Zhang, Yue Hu, Wen-Qi Shan, Zhi-Hong Wang, Qing-Yue Fu, Dan-Ni Fu, Jiang Ji, Tong Li. Formalin Itch Test: Low-Dose Formalin Induces Histamine-Independent, TRPA1-Mediated Itch in Mice. Frontiers in medicine. vol 8. 2021-03-10. PMID:33681255. further, we found that 0.3% formalin-induced scratching was histamine-independent and significantly attenuated by transient receptor potential ion channel a1 (trpa1) inhibitor (hc030031) or in trpa1 knockout (ko) mice, but not affected by transient receptor potential ion channel v1 (trpv1) inhibitor (capsazepine) or in trpv1 ko mice. 2021-03-10 2023-08-13 mouse
Jennifer Bialecki, Allison Werner, Nicholas L Weilinger, Catharine M Tucker, Haley A Vecchiarelli, Jon Egaña, Juan Mendizabal-Zubiaga, Pedro Grandes, Matthew N Hill, Roger J Thompso. Suppression of Presynaptic Glutamate Release by Postsynaptic Metabotropic NMDA Receptor Signalling to Pannexin-1. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 40. issue 4. 2020-07-23. PMID:31818976. this facilitated glutamate release was absent in transient receptor potential vanilloid 1 (trpv1) ko mice and prevented by the trpv1 antagonist, capsazepine, suggesting it required presynaptic trpv1. 2020-07-23 2023-08-13 mouse
H Inagaki, E Kurganov, Y Park, E Furube, S Miyat. Oral gavage of capsaicin causes TRPV1-dependent acute hypothermia and TRPV1-independent long-lasting increase of locomotor activity in the mouse. Physiology & behavior. vol 206. 2020-07-02. PMID:31009639. oral gavage of cap induced neuronal fos expression in the circumventricular organs, median and medial preoptic area, arcuate nucleus, and nucleus of the solitary tract, whereas neuronal fos expression was scarcely observed in trpv1 ko mice. 2020-07-02 2023-08-13 mouse
Consuelo Amantini, Valerio Farfariello, Claudio Cardinali, Maria Beatrice Morelli, Oliviero Marinelli, Massimo Nabissi, Matteo Santoni, Laura Bonfili, Valentina Cecarini, Anna Maria Eleuteri, Giorgio Santon. The TRPV1 ion channel regulates thymocyte differentiation by modulating autophagy and proteasome activity. Oncotarget. vol 8. issue 53. 2019-11-20. PMID:29207602. in addition, positive selection of thymocytes triggered by anti-tcrβ/cd2 ab-mediated costimulation induces apoptosis in thymocytes from trpv1 ko as compared with wt mice. 2019-11-20 2023-08-13 mouse
Takuya Kameda, Joel Zvick, Miriam Vuk, Aleksandra Sadowska, Wai Kit Tam, Victor Y Leung, Kata Bölcskei, Zsuzsanna Helyes, Lee Ann Applegate, Oliver N Hausmann, Juergen Klasen, Olga Krupkova, Karin Wuertz-Koza. Expression and Activity of TRPA1 and TRPV1 in the Intervertebral Disc: Association with Inflammation and Matrix Remodeling. International journal of molecular sciences. vol 20. issue 7. 2019-07-30. PMID:30974795. the matrix structure and composition in caudal motion segments from trpa1 and trpv1 wild-type (wt) and knock-out (ko) mice was visualized by fast staining. 2019-07-30 2023-08-13 mouse
Lukas Hofmann, Dorothea Hose, Anne Grießhammer, Robert Blum, Frank Döring, Sulayman Dib-Hajj, Stephen Waxman, Claudia Sommer, Erhard Wischmeyer, Nurcan Üçeyle. Characterization of small fiber pathology in a mouse model of Fabry disease. eLife. vol 7. 2019-03-11. PMID:30328411. old gla ko mice show increased trpv1 protein in drg neurons and heat hypersensitivity upon i.pl. 2019-03-11 2023-08-13 mouse
Roberto De Luca, Karolina Mazur, Anna Kernder, Tatsiana Suvorava, Georg Kojda, Helmut L Haas, Olga A Sergeev. Mechanisms of N-oleoyldopamine activation of central histaminergic neurons. Neuropharmacology. vol 143. 2019-02-25. PMID:30219501. the dopamine uptake blocker nomifensine blanked olda-excitation and dopamine receptor antagonists abolished the olda action in trpv1 ko mice. 2019-02-25 2023-08-13 mouse
Olga A Sergeeva, Roberto De Luca, Karolina Mazur, Aissa N Chepkova, Helmut L Haas, Andreas Baue. N-oleoyldopamine modulates activity of midbrain dopaminergic neurons through multiple mechanisms. Neuropharmacology. vol 119. 2017-08-31. PMID:28400256. in ventral tegmental area (vta) da neurons from trpv1 ko mice a transient inhibition of firing by olda was observed. 2017-08-31 2023-08-13 mouse
Lawrence M Carey, Richard A Slivicki, Emma Leishman, Ben Cornett, Ken Mackie, Heather Bradshaw, Andrea G Hohman. A pro-nociceptive phenotype unmasked in mice lacking fatty-acid amide hydrolase. Molecular pain. vol 12. 2016-12-26. PMID:27178246. nonetheless, intradermal injection of the transient receptor potential channel v1 (trpv1) agonist capsaicin increased nocifensive behavior as well as mechanical and heat hypersensitivity in faah ko relative to wild-type mice. 2016-12-26 2023-08-13 mouse
Lawrence M Carey, Richard A Slivicki, Emma Leishman, Ben Cornett, Ken Mackie, Heather Bradshaw, Andrea G Hohman. A pro-nociceptive phenotype unmasked in mice lacking fatty-acid amide hydrolase. Molecular pain. vol 12. 2016-12-26. PMID:27178246. when central sensitization was established, faah ko mice displayed elevated levels of anandamide, other fatty-acid amides, and endogenous trpv1 agonists in both paw skin and lumbar spinal cord relative to wild-type mice. 2016-12-26 2023-08-13 mouse