All Relations between ko and trpv4

Publication Sentence Publish Date Extraction Date Species
Antonio Cibelli, Maria Grazia Mola, Emanuela Saracino, Barbara Barile, Pasqua Abbrescia, Guido Mogni, David C Spray, Eliana Scemes, Andrea Rossi, Diletta Spennato, Maria Svelto, Antonio Frigeri, Valentina Benfenati, Grazia Paola Nicchi. Aquaporin-4 and transient receptor potential vanilloid 4 balance in early postnatal neurodevelopment. Glia. 2024-02-16. PMID:38362923. the present study aimed at investigating the contribution of aqp4 and trpv4 to cns early postnatal development using wt and aqp4 ko brain and retina and neuronal stem cells (nscs), as an in vitro model of astrocyte differentiation. 2024-02-16 2024-02-18 Not clear
Jijun Xu, Ping Huang, Bihua Bie, Yang Dai, Salma Ben-Salem, Nozha Borjini, Lingjun Zhang, Jin Chen, Mitchell Olman, Jianguo Cheng, Feng Li. Complement Receptor C3aR1 Contributes to Paclitaxel-Induced Peripheral Neuropathic Pain in Mice and Rats. Journal of immunology (Baltimore, Md. : 1950). 2023-10-20. PMID:37861348. we also found that paclitaxel induced less severe pima, along with a reduced drg expression of transient receptor potential channels of the vanilloid subtype 4 (trpv4), an essential mediator for pima, in c3ar1 ko than in wt mice. 2023-10-20 2023-11-08 mouse
Hideki Sakatani, Masamitsu Kono, Tatsuya Shiga, Hiroki Kuwazoe, Denisa Nanushaj, Ibu Matsuzaki, Shin-Ichi Murata, Masayasu Miyajima, Yuka Okada, Shizuya Saika, Muneki Hotom. The Roles of Transient Receptor Potential Vanilloid 1 and 4 in Olfactory Regeneration. Laboratory investigation; a journal of technical methods and pathology. vol 103. issue 4. 2023-03-04. PMID:36870285. trpv1 knockout (ko), trpv4 ko, and wild-type (wt) mice were used to model methimazole-induced olfactory dysfunction. 2023-03-04 2023-08-14 mouse
Hideki Sakatani, Masamitsu Kono, Tatsuya Shiga, Hiroki Kuwazoe, Denisa Nanushaj, Ibu Matsuzaki, Shin-Ichi Murata, Masayasu Miyajima, Yuka Okada, Shizuya Saika, Muneki Hotom. The Roles of Transient Receptor Potential Vanilloid 1 and 4 in Olfactory Regeneration. Laboratory investigation; a journal of technical methods and pathology. vol 103. issue 4. 2023-03-04. PMID:36870285. postinjury oe thickness improved faster in trpv4 ko mice than wt mice but without acceleration of orn maturation. 2023-03-04 2023-08-14 mouse
Jolien Beeken, Melanie Mertens, Nathan Stas, Sofie Kessels, Liese Aerts, Bieke Janssen, Femke Mussen, Silvia Pinto, Rudi Vennekens, Jean-Michel Rigo, Laurent Nguyen, Bert Brône, Yeranddy A Alpiza. Acute inhibition of transient receptor potential vanilloid-type 4 cation channel halts cytoskeletal dynamism in microglia. Glia. 2022-07-09. PMID:35809029. here we show that acute inhibition of trpv4, but not its constitutive absence in the trpv4 ko cells, affects the morphology and motility of microglia in vitro. 2022-07-09 2023-08-14 Not clear
Marwan Mannaa, Lajos Markó, András Balogh, Emilia Vigolo, Gabriele N'diaye, Mario Kaßmann, Laura Michalick, Ulrike Weichelt, Kai M Schmidt-Ott, Wolfgang B Liedtke, Yu Huang, Dominik N Müller, Wolfgang M Kuebler, Maik Gollasc. Transient Receptor Potential Vanilloid 4 Channel Deficiency Aggravates Tubular Damage after Acute Renal Ischaemia Reperfusion. Scientific reports. vol 8. issue 1. 2019-11-04. PMID:29559678. detailed histological analysis revealed that iri caused aggravated renal tubular damage in trpv4 ko mice, especially in the renal cortex. 2019-11-04 2023-08-13 mouse
Mitsuharu Yoshiyama, Tsutomu Mochizuki, Hiroshi Nakagomi, Tatsuya Miyamoto, Satoru Kira, Ryoji Mizumachi, Takaaki Sokabe, Yasunori Takayama, Makoto Tominaga, Masayuki Taked. Functional roles of TRPV1 and TRPV4 in control of lower urinary tract activity: dual analysis of behavior and reflex during the micturition cycle. American journal of physiology. Renal physiology. vol 308. issue 10. 2015-08-04. PMID:25761879. in metabolic cage experiments conducted under conscious conditions (i.e., voluntary voiding behavior), trpv4 ko mice showed a markedly higher voiding frequency (vf; 19.3 ± 1.2 times/day) and a smaller urine volume/voiding (uvv; 114 ± 9 μl) compared with wild-type (wt) littermates (vf: 5.2 ± 0.5 times/day and uvv: 380 ± 34 μl). 2015-08-04 2023-08-13 mouse
Claire A Sand, Anna Starr, Manasi Nandi, Andrew D Gran. Blockade or deletion of transient receptor potential vanilloid 4 (TRPV4) is not protective in a murine model of sepsis. F1000Research. vol 4. 2015-06-11. PMID:26064477. multi-parameter monitoring of conscious systemic haemodynamics (by radiotelemetry probe), mesenteric microvascular blood flow (laser speckle contrast imaging) and blood biochemistry (istat blood gas analysis) was carried out in wild type (wt) and trpv4 knockout (ko) mice. 2015-06-11 2023-08-13 mouse
Travis E Brown, Anda M Chirila, Benjamin R Schrank, Julie A Kaue. Loss of interneuron LTD and attenuated pyramidal cell LTP in Trpv1 and Trpv3 KO mice. Hippocampus. vol 23. issue 8. 2014-03-05. PMID:23536486. here we tested the role of other trpv channels in hippocampal synaptic plasticity, using hippocampal slices from trpv1, trpv3 and trpv4 knockout (ko) mice. 2014-03-05 2023-08-12 mouse
Travis E Brown, Anda M Chirila, Benjamin R Schrank, Julie A Kaue. Loss of interneuron LTD and attenuated pyramidal cell LTP in Trpv1 and Trpv3 KO mice. Hippocampus. vol 23. issue 8. 2014-03-05. PMID:23536486. ltd at excitatory synapses on s. radiatum hippocampal interneurons was attenuated in slices from trpv3 ko mice (as well as in trpv1 ko mice as previously reported), but not in slices from trpv4 ko mice. 2014-03-05 2023-08-12 mouse