| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Goichi Beck, Rika Yamashita, Kansuke Kido, Kensuke Ikenaka, Tomoya Chiba, Yuki Yonenobu, Yuko Saito, Eiichi Morii, Masato Hasegawa, Shigeo Murayama, Hideki Mochizuk. An autopsy case of progressive supranuclear palsy treated with monoclonal antibody against tau. Neuropathology : official journal of the Japanese Society of Neuropathology. 2023-01-03. PMID:36593715. |
neuropathological examination demonstrated neuronal loss, gliosis, and widespread deposits of phosphorylated tau in the neurofibrillary tangles, tufted astrocytes, coiled bodies, and threads, which mainly occurred in the inferior olive nucleus, dentate nucleus of the cerebellum, substantia nigra, midbrain tegmentum, subthalamic nuclei, globus pallidus, putamen, and precentral gyrus, confirming typical psp pathology. |
2023-01-03 |
2023-08-14 |
Not clear |
| Ryuichi Koizumi, Akio Akagi, Yuichi Riku, Jun Sone, Hiroaki Miyahara, Fumiaki Tanaka, Mari Yoshida, Yasushi Iwasak. Clinicopathological features of progressive supranuclear palsy with asymmetrical atrophy of the superior cerebellar peduncle. Neuropathology : official journal of the Japanese Society of Neuropathology. 2022-10-12. PMID:36222051. |
the atrophic side of the scp corresponded to the dominant side of the tau pathology in the cerebellar dentate nucleus. |
2022-10-12 |
2023-08-14 |
Not clear |
| Chiho Ishida, Yuko Kato-Motozaki, Daisuke Noto, Kiyonobu Komai, Masato Hasegawa, Takeshi Ikeuchi, Masahito Yamad. An autopsy case of corticobasal degeneration with inferior olivary hypertrophy. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 41. issue 3. 2021-11-25. PMID:33847035. |
the distribution of tau deposits was prominent in the deeper affected lesions of the dentate nucleus and inferior olivary nucleus. |
2021-11-25 |
2023-08-13 |
Not clear |
| T Homma, Y Mochizuki, M Hara, S Kamei, T Mizutani, H Takubo, E Isozaki, M Takahashi, T Komori, H Ha. Gradient subthalamic neurodegeneration and tau pathology in the hypoglossal nucleus as essential pathological markers of progressive supranuclear palsy - Richardson syndrome. Revue neurologique. vol 176. issue 5. 2020-11-02. PMID:32247606. |
this study confirmed the following neuropathological characteristics of psp-rs: (1) neurodegeneration usually affects the striatonigral system and cerebellar dentate nucleus; (2) the cerebellar afferent system in psp-rs is affected by absent-to-mild neurodegeneration; and (3) the extent of tau distribution throughout the central nervous system is greater than the extent of neurodegeneration. |
2020-11-02 |
2023-08-13 |
Not clear |
| Keqing Zhu, Xin Wang, Bing Sun, Juanli Wu, Hui Lu, Xiaoling Zhang, Huazheng Liang, Dandan Zhang, Chong Li. Primary Age-Related Tauopathy in Human Subcortical Nuclei. Frontiers in neuroscience. vol 13. 2020-10-01. PMID:31191227. |
expression of tau was frequently found in subcortical nuclei including the substantia nigra, inferior colliculus, locus coeruleus, medulla oblongata in the brainstem, the caudate, putamen, nucleus globus pallidus in the striatum, the hypothalamus, thalamus, subthalamus in the diencephalon, and the cervical spinal cord in both part and ad, but not in the dentate nucleus of the cerebellum. |
2020-10-01 |
2023-08-13 |
human |
| Yasushi Iwasaki, Keiko Mori, Masumi Ito, Maya Mimuro, Mari Yoshid. [An autopsied case of progressive supranuclear palsy, initially diagnosed as spinocerebellar degeneration with severe olivopontocerebellar involvement]. Rinsho shinkeigaku = Clinical neurology. vol 51. issue 10. 2011-12-20. PMID:22019867. |
tau positive inclusions in the purkinje neurons, bergmann glias and dentate nucleus neurons were observed. |
2011-12-20 |
2023-08-12 |
Not clear |
| David R Williams, Janice L Holton, Catherine Strand, Alan Pittman, Rohan de Silva, Andrew J Lees, Tamas Reves. Pathological tau burden and distribution distinguishes progressive supranuclear palsy-parkinsonism from Richardson's syndrome. Brain : a journal of neurology. vol 130. issue Pt 6. 2007-06-27. PMID:17525140. |
using only the grade of coiled body + thread lesions in the substantia nigra, caudate and dentate nucleus, a reliable and repeatable 12-tiered grading system was established (psp-tau score: 0, mild tau pathology, restricted distribution; >7, severe, widespread tau pathology). |
2007-06-27 |
2023-08-12 |
Not clear |
| Takahiko Umahara, Toshiki Uchihara, Saburo Yagishita, Ayako Nakamura, Kuniaki Tsuchiya, Toshihiko Iwamot. Intranuclear immunolocalization of 14-3-3 protein isoforms in brains with spinocerebellar ataxia type 1. Neuroscience letters. vol 414. issue 2. 2007-05-08. PMID:17224237. |
pontine neurons intensely positive for beta, purkinje cells for tau and dentate nucleus neurons for both, while all of those neurons were consistently positive for zeta isoform, although sigma isoform tended to be located in the cytoplasm. |
2007-05-08 |
2023-08-12 |
human |
| K Ishizawa, W L Lin, P Tiseo, W G Honer, P Davies, D W Dickso. A qualitative and quantitative study of grumose degeneration in progressive supranuclear palsy. Journal of neuropathology and experimental neurology. vol 59. issue 6. 2000-06-20. PMID:10850864. |
gd was associated with demyelination, axonal loss, glial tau pathology, and microgliosis in regions juxtaposed to the dentate nucleus (dn). |
2000-06-20 |
2023-08-12 |
Not clear |
| K Arima, S Murayama, S Oyanagi, T Akashi, T Inos. Presenile dementia with progressive supranuclear palsy tangles and Pick bodies: an unusual degenerative disorder involving the cerebral cortex, cerebral nuclei, and brain stem nuclei. Acta neuropathologica. vol 84. issue 2. 1992-10-15. PMID:1381857. |
immunocytochemical study using anti-phosphorylated tau and anti-ubiquitin antibodies in conjunction with ultrastructural observations revealed two types of inclusions: neurofibrillary tangles (nfts) of progressive supranuclear palsy (psp) in the edinger-westphal nucleus, locus coeruleus, cerebellar dentate nucleus, inferior olivary nucleus, and posterior horn of the spinal cord; and pick bodies (pbs) in the atrophied cerebral cortex and red nucleus. |
1992-10-15 |
2023-08-11 |
Not clear |