All Relations between microtubule-associated protein tau and hippocampus

Reference Sentence Publish Date Extraction Date Species
Miriam Zamorano, Jenolyn F Alexander, Desiree Catania, Shruti Dharmaraj, Annemieke Kavelaars, Cobi J Heijne. Nasal administration of mesenchymal stem cells prevents accelerated age-related tauopathy after chemotherapy in mice. Immunity & ageing : I & A vol 20 issue 1 2023 36698170 we showed recently that treatment of 9-month-old male mice with cisplatin causes cognitive deficits that are associated with formation of tau deposits in the hippocampus. 2023-01-26 2023-01-31 mouse
Bastien Herli. Hippocampal sclerosis linked to epilepsy: clinical consequences, histopathology and evolution with aging Geriatrie et psychologie neuropsychiatrie du vieillissement vol 20 issue 4 2023 36700444 hippocampal sclerosis is associated with amyloid and tau deposits inside the hippocampus, which increases with the subjects\xe2\x80\x99 age. 2023-01-26 2023-01-31 human
Bastien Herli. Hippocampal sclerosis linked to epilepsy: clinical consequences, histopathology and evolution with aging Geriatrie et psychologie neuropsychiatrie du vieillissement vol 20 issue 4 2023 36700444 those deposits pattern is close to the one observed in patients with tau / amylo\xc3\xafd neurodegenerative diseases, which demonstrates a bilateral relationship between epilepsy, hippocampal sclerosis, and neurodegenerative diseases. 2023-01-26 2023-01-31 human
Guoliang Fang, Jiexiu Zhao, Pengfei Li, Liang Li, Tao Yu, Xingya Yang, Zihong He, Ye Tia. Long-term treadmill exercise inhibits neuronal cell apoptosis and reduces tau phosphorylation in the cerebral cortex and hippocampus of aged rats. Science bulletin vol 62 issue 11 2023 36659268 long-term treadmill exercise inhibits neuronal cell apoptosis and reduces tau phosphorylation in the cerebral cortex and hippocampus of aged rats. 2023-01-20 2023-01-30 rat
Gouri Patil, Shabda Kulsange, Rubina Kazi, Tejas Chirmade, Vaikhari Kale, Chandrashekhar Mote, Manoj Aswar, Santosh Koratkar, Sachin Agawane, Mahesh Kulkarn. Behavioral and Proteomic Studies Reveal Methylglyoxal Activate Pathways Associated with Alzheimer's Disease. ACS pharmacology & translational science vol 6 issue 1 2023 36654748 the hippocampal tau phosphorylation level was increased in mgo treated rats, which was reduced in the presence of aminoguanidine and telmisartan. 2023-01-19 2023-01-30 rat
Nikhil Dave, Jessica M Judd, Annika Decker, Wendy Winslow, Patrick Sarette, Oscar Villarreal Espinosa, Savannah Tallino, Samantha K Bartholomew, Alina Bilal, Jessica Sandler, Ian McDonough, Joanna K Winstone, Erik A Blackwood, Christopher Glembotski, Timothy Karr, Ramon Velazque. Dietary choline intake is necessary to prevent systems-wide organ pathology and reduce Alzheimer's disease hallmarks. Aging cell vol issue 2023 36642814 tissue analyses showed cardiac and liver pathology, elevated soluble and insoluble amyloid-\xce\xb2 and thioflavin s structures, and tau hyperphosphorylation at various pathological epitopes in the hippocampus and cortex of 3xtg-ad ch- mice. 2023-01-16 2023-01-30 mouse
Hai Duc Nguyen, Won Hee Jo, Ngoc Hong Minh Hoang, Min-Sun Ki. Risperidone ameliorated 1,2-Diacetylbenzene-induced cognitive impairments in mice via activating prolactin signaling pathways. International immunopharmacology vol 115 issue 2023 36641890 risperidone alleviated dab-induced cognitive impairment in hippocampal mice, possibly by inhibiting gsk-3\xce\xb2, \xce\xb2-amyloid, cdk5, bace, and tau hyperphosphorylation. 2023-01-15 2023-01-30 mouse
Junghyung Park, Jinyoung Won, Chang-Yeop Jeon, Kyung Seob Lim, Won Seok Choi, Sung-Hyun Park, Jincheol Seo, Jiyeon Cho, Jung Bae Seong, Hyeon-Gu Yeo, Keonwoo Kim, Yu Gyeong Kim, Minji Kim, Kyung Sik Yi, Youngjeon Le. XperCT-guided Intra-cisterna Magna Injection of Streptozotocin for Establishing an Alzheimer's Disease Model Using the Cynomolgus Monkey ( Experimental neurobiology vol 31 issue 6 2023 36631849 the monkeys subjected to xperct-based stz injection via the icm route showed features of ad pathology, including markedly enhanced neuronal loss, synaptic impairment, and tau phosphorylation in the hippocampus. 2023-01-11 2023-01-30 human
Arunkumar Subramanian, T Tamilanban, Abdulrhman Alsayari, Gobinath Ramachawolran, Ling Shing Wong, Mahendran Sekar, Siew Hua Gan, Vetriselvan Subramaniyan, Suresh V Chinni, Nur Najihah Izzati Mat Rani, Nagaraja Suryadevara, Shadma Waha. Trilateral association of autophagy, mTOR and Alzheimer's disease: Potential pathway in the development for Alzheimer's disease therapy. Frontiers in pharmacology vol 13 issue 2023 36618946 alzheimer's disease (ad) is the chief cause of progressive dementia, and it is characterized by irreparable loss of cognitive abilities, forming senile plaques having amyloid beta (a\xce\xb2) aggregates and neurofibrillary tangles with considerable amounts of tau in affected hippocampus and cortex regions of human brains. 2023-01-09 2023-01-30 human
Young-Kook Kim, Yoon Seok Jung, Juhyun Son. Transcriptome Profile in the Mouse Brain of Hepatic Encephalopathy and Alzheimer's Disease. International journal of molecular sciences vol 24 issue 1 2023 36614117 alzheimer's disease (ad), the most common neurodegenerative disease, is characterized by tau hyperphosphorylation, excessive amyloid beta (a\xce\xb2) accumulation, the formation of fibrillary tangles, hippocampus atrophy, and neuroinflammation. 2023-01-08 2023-01-30 mouse
Zheng Liang, Xiaokang Gong, Runjia Ye, Yang Zhao, Jin Yu, Yanna Zhao, Jian Ba. Long-Term High-Fat Diet Consumption Induces Cognitive Decline Accompanied by Tau Hyper-Phosphorylation and Microglial Activation in Aging. Nutrients vol 15 issue 1 2023 36615907 compared with the nd group, the hfd-fed mice showed tau hyperphosphorylation at ps214 in the hippocampus and at ps422 and ps396 in the cortex, which was accompanied by gsk-3\xce\xb2 activation. 2023-01-08 2023-01-30 mouse
Thamires Naela Cardoso Magalh\\xc3\\xa3es, Raphael Fernandes Casseb, Christian Luiz Baptista Gerbelli, Luciana Ramalho Pimentel-Siva, Mateus Henrique Nogueira, Camila Vieira Ligo Teixeira, Ana Fl\\xc3\\xa1via Mac Knight Carletti, Thiago Junqueira Ribeiro de Rezende, Helena Passarelli Giroud Joaquim, Leda Leme Talib, Orestes Vicente Forlenza, Fernando Cendes, Marcio Luiz Figueredo Balthaza. Whole-brain DTI parameters associated with tau protein and hippocampal volume in Alzheimer's disease. Brain and behavior vol issue 2023 36601694 whole-brain dti parameters associated with tau protein and hippocampal volume in alzheimer's disease. 2023-01-05 2023-01-30 Not clear
Allegra Kawles, Grace Minogue, Antonia Zouridakis, Rachel Keszycki, Nathan Gill, Caren Nassif, Christina Coventry, Hui Zhang, Emily Rogalski, Margaret E Flanagan, Rudolph Castellani, Eileen H Bigio, M Marsel Mesulam, Changiz Geula, Tamar Gefe. Differential vulnerability of the dentate gyrus to tauopathies in dementias. Acta neuropathologica communications vol 11 issue 1 2023 36597124 the dentate gyrus (dg), a key hippocampal subregion in memory processing, generally resists phosphorylated tau accumulation in the amnestic dementia of the alzheimer's type due to alzheimer's disease (dat-ad), but less is known about the susceptibility of the dg to other tauopathies. 2023-01-03 2023-01-30 human
Allegra Kawles, Grace Minogue, Antonia Zouridakis, Rachel Keszycki, Nathan Gill, Caren Nassif, Christina Coventry, Hui Zhang, Emily Rogalski, Margaret E Flanagan, Rudolph Castellani, Eileen H Bigio, M Marsel Mesulam, Changiz Geula, Tamar Gefe. Differential vulnerability of the dentate gyrus to tauopathies in dementias. Acta neuropathologica communications vol 11 issue 1 2023 36597124 we conclude that the dg is differentially vulnerable to pathologic tau accumulation, raising intriguing questions about the structural integrity and functional significance of hippocampal circuits in neurodegenerative dementias. 2023-01-03 2023-01-30 human
Regina T Vontell, Juan Pablo de Rivero Vaccari, Xiaoyan Sun, Sakir Humayun Gultekin, Helen M Bramlett, W Dalton Dietrich, Robert W Kean. Identification of inflammasome signaling proteins in neurons and microglia in early and intermediate stages of Alzheimer's disease. Brain pathology (Zurich, Switzerland) vol issue 2022 36579934 we performed analysis of hippocampal thickness, \xce\xb2-amyloid plaques, and hyperphosphorylated tau to ascertain the cellular pathological changes that occur between low and intermediate ad pathology. 2022-12-29 2023-01-30 Not clear
Yu-Xiao Wan, Guang Shi, Ling-Yan Jian, Xin-Yu Fa. Blockade of endocannabinoid system by oxytocin attenuates memory deficits in oxycodone-treated rats. Addiction biology vol 28 issue 1 2022 36577736 this finding was accompanied by elevation of pser396, pser404 in the tau, and reduction of the number of neurons, dendritic spines and synaptic density in the hippocampus. 2022-12-28 2023-01-30 rat
Mariana G Fronza, Manoela Sacramento, Diego Alves, Domenico Pratic\\xc3\\xb2, Lucielli Savegnag. QTC-4-MeOBnE Ameliorated Depressive-Like Behavior and Memory Impairment in 3xTg Mice. Molecular neurobiology vol issue 2022 36567360 among them, the reduction of amyloid beta (a\xce\xb2) production mediated by changes in amyloid precursor protein metabolism and hippocampal tau phosphorylation through the inhibition of kinases. 2022-12-25 2023-01-30 mouse
Hongtao Shen, Tianzhen Zhang, Yao Ji, Yu Zhang, Yongxiang Wang, Yuling Jiang, Xiongjin Chen, Qiuhao Liang, Kefeng Wu, Yunfeng Li, Xingyu Lu, Lili Cui, Bin Zhao, Yan Wan. GRK5 Deficiency in the Hippocampus Leads to Cognitive Impairment via Abnormal Microglial Alterations. Molecular neurobiology vol issue 2022 36525154 here, we reported that mice with reduced grk5 in the hippocampus exhibit cognitive impairment and some alzheimer's disease (ad)-related molecular pathologies, such as significant neuronal damage and loss, enhanced tau protein phosphorylation, and increased levels of a\xce\xb2 peptides in the hippocampus. 2022-12-16 2023-01-30 mouse
Laurel A Becket. Alzheimer's-related brain damage shows sex-specific links with risk factors. PLoS biology vol 20 issue 12 2022 36516115 alzheimer's disease is marked by brain damage from tau and amyloid aggregates, particularly to the hippocampus and the default network. 2022-12-14 2023-01-30 Not clear
Vani Jangra, Jeshnu Topl. Can Alzheimer's Disease Be Secondary to Type-2 Diabetes Mellitus? Cureus vol 14 issue 11 2022 36505102 thirdly, several pathological research has also shown that beta-amyloid plaques, hyperphosphorylated tau protein, and brain shrinkage, particularly in the hippocampus, are shared brain lesions between insulin and alzheimer's disease.\xc2\xa0in light of this, type 2 diabetes mellitus may be viewed as a liability for dementia and alzheimer's disease. 2022-12-12 2023-01-30 human
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