All Relations between microtubule-associated protein tau and hippocampus

Publication Sentence Publish Date Extraction Date Species
Hend M Hussien, Doaa A Ghareeb, Hany E A Ahmed, Hani S Hafez, Samar R Sale. Pharmacological implications of ipriflavone against environmental metal-induced neurodegeneration and dementia in rats. Environmental science and pollution research international. vol 28. issue 46. 2021-12-02. PMID:34235690. neuropathological biomarkers including oxidative stress (tbars, no, sod, gpx, gst, and gsh), inflammation (tnf- α, il-6, and il-1β), neurotransmission (ache and mao), and insulin resistance (insulin, insulin receptor, and insulin-degrading enzyme) were altered, which consequently elevated the level of amyloid-β42 and tau protein in the hippocampus tissues inducing neuronal injury. 2021-12-02 2023-08-13 rat
Juan D Rodriguez-Callejas, Eberhard Fuchs, Claudia Perez-Cru. Increased oxidative stress, hyperphosphorylation of tau, and dystrophic microglia in the hippocampus of aged Tupaia belangeri. Glia. vol 68. issue 9. 2021-11-30. PMID:32096580. increased oxidative stress, hyperphosphorylation of tau, and dystrophic microglia in the hippocampus of aged tupaia belangeri. 2021-11-30 2023-08-13 Not clear
Juan D Rodriguez-Callejas, Eberhard Fuchs, Claudia Perez-Cru. Increased oxidative stress, hyperphosphorylation of tau, and dystrophic microglia in the hippocampus of aged Tupaia belangeri. Glia. vol 68. issue 9. 2021-11-30. PMID:32096580. adult (mean age 3.8 years), old (mean age 6 years), and aged (mean age 7.5 years) tree shrews were used for histochemical and immunostaining techniques to determine ferritin and iba1 positive microglia, iron tissue content, tau hyperphosphorylation and oxidized-rna in dentate gyrus, subiculum, and ca1-ca3 hippocampal regions. 2021-11-30 2023-08-13 Not clear
Juan D Rodriguez-Callejas, Eberhard Fuchs, Claudia Perez-Cru. Increased oxidative stress, hyperphosphorylation of tau, and dystrophic microglia in the hippocampus of aged Tupaia belangeri. Glia. vol 68. issue 9. 2021-11-30. PMID:32096580. with aging, oxidative damage to rna (8ohg) increased significantly in all hippocampal regions, while tau hyperphosphorylation (at100) was enhanced in dg, ca3, and sub in aged animals. 2021-11-30 2023-08-13 Not clear
Bora Yoon, Tengfei Guo, Karine Provost, Deniz Korman, Tyler J Ward, Susan M Landau, William J Jagus. Abnormal tau in amyloid PET negative individuals. Neurobiology of aging. vol 109. 2021-11-26. PMID:34715443. we compared a-t- (n = 316), a-t+ (n = 63), and a+t+ (n = 182) individuals on demographics, amyloid, tau, hippocampal volumes, and cognition. 2021-11-26 2023-08-13 human
Bora Yoon, Tengfei Guo, Karine Provost, Deniz Korman, Tyler J Ward, Susan M Landau, William J Jagus. Abnormal tau in amyloid PET negative individuals. Neurobiology of aging. vol 109. 2021-11-26. PMID:34715443. the severity of tau deposition, hippocampal atrophy, and cognitive dysfunction in the a-t+ group was intermediate between a-t- and a+t+ (all p < 0.001). 2021-11-26 2023-08-13 human
Sarah Helena Nies, Hideyuki Takahashi, Charlotte S Herber, Anita Huttner, Alison Chase, Stephen M Strittmatte. Spreading of Alzheimer tau seeds is enhanced by aging and template matching with limited impact of amyloid-β. The Journal of biological chemistry. vol 297. issue 4. 2021-11-25. PMID:34480901. the density and spreading of tau inclusions triggered by human tau seed were unaltered in the hippocampus and cortex of appswe/psen1Δe9 transgenic and app 2021-11-25 2023-08-13 mouse
Jorge A Sierra-Fonseca, Minerva Rodriguez, Anapaula Themann, Omar Lira, Francisco J Flores-Ramirez, Javier Vargas-Medrano, Bharathi S Gadad, Sergio D Iñigue. Autophagy Induction and Accumulation of Phosphorylated Tau in the Hippocampus and Prefrontal Cortex of Adult C57BL/6 Mice Subjected to Adolescent Fluoxetine Treatment. Journal of Alzheimer's disease : JAD. vol 83. issue 4. 2021-11-24. PMID:34420960. autophagy induction and accumulation of phosphorylated tau in the hippocampus and prefrontal cortex of adult c57bl/6 mice subjected to adolescent fluoxetine treatment. 2021-11-24 2023-08-13 mouse
Shinobu Kawakatsu, Ryota Kobayashi, Hiroshi Hayashi, Daichi Morioka, Aya Utsunomiya, Takanobu Kabasawa, Rintaro Ohe, Koichi Otan. Clinicopathological heterogeneity of Alzheimer's disease with pure Alzheimer's disease pathology: Cases associated with dementia with Lewy bodies, very early-onset dementia, and primary progressive aphasia. Neuropathology : official journal of the Japanese Society of Neuropathology. 2021-11-24. PMID:34816507. tau deposits were also abundant in the cerebral neocortex, hippocampus, basal ganglia, and brain stem. 2021-11-24 2023-08-13 Not clear
Jacob Raber, Ruby Perez, Eileen Ruth S Torres, Destine Krenik, Sydney Boutros, Esha Patel, Anna C Chlebowski, Estefania Ramos Torres, Zakia Perveen, Arthur Penn, Daniel B Paulsen, Michael G Bartlett, Enze Jia, Sarah Holden, Reed Hall, Jeffrey Morré, Carmen Wong, Emily Ho, Jaewoo Choi, Jan Frederik Stevens, Alexandra Noël, Gerd Bobe, Glen Kisb. Effects of Chronic Secondhand Smoke (SHS) Exposure on Cognitive Performance and Metabolic Pathways in the Hippocampus of Wild-Type and Human Tau Mice. Environmental health perspectives. vol 129. issue 5. 2021-11-23. PMID:34009016. effects of chronic secondhand smoke (shs) exposure on cognitive performance and metabolic pathways in the hippocampus of wild-type and human tau mice. 2021-11-23 2023-08-13 mouse
Jacob Ziontz, Jenna N Adams, Theresa M Harrison, Suzanne L Baker, William J Jagus. Hippocampal Connectivity with Retrosplenial Cortex is Linked to Neocortical Tau Accumulation and Memory Function. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 42. 2021-11-23. PMID:34531286. hippocampal connectivity with retrosplenial cortex is linked to neocortical tau accumulation and memory function. 2021-11-23 2023-08-13 human
Jacob Ziontz, Jenna N Adams, Theresa M Harrison, Suzanne L Baker, William J Jagus. Hippocampal Connectivity with Retrosplenial Cortex is Linked to Neocortical Tau Accumulation and Memory Function. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 42. 2021-11-23. PMID:34531286. functional connectivity between hippocampus (hc) and retrosplenial cortex (rsc), a key region of the medial parietal lobe, was associated with tau in medial parietal lobe. 2021-11-23 2023-08-13 human
Anthoni M Goodman, Bethany M Langner, Nateka Jackson, Capri Alex, Lori L McMaho. Heightened Hippocampal β-Adrenergic Receptor Function Drives Synaptic Potentiation and Supports Learning and Memory in the TgF344-AD Rat Model during Prodromal Alzheimer's Disease. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 26. 2021-11-22. PMID:33952633. in fact, the locus coeruleus (lc), the sole source of norepinephrine (ne) for >90% of the brain, is the first site of pathologic tau accumulation in human ad with axon loss throughout forebrain, including hippocampus. 2021-11-22 2023-08-13 human
Hongchun Li, Wei Xu, Denian Wang, Liang Wang, Qiyao Fang, Xuemei Wan, Jiamei Zhang, Yiming Hu, Huifang Li, Jie Zhang, Zhen Yang, Chunqi Liu, Xiaocong Liu, Yonghai Wang, Bin Liu, Zhengtao Hu, Ying Zhao, Qian Bu, Hongbo Wang, Jingwei Tian, Yinglan Zhao, Xiaobo Ce. 4R Tau Modulates Cocaine-Associated Memory through Adult Dorsal Hippocampal Neurogenesis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 31. 2021-11-22. PMID:34099513. 4r tau modulates cocaine-associated memory through adult dorsal hippocampal neurogenesis. 2021-11-22 2023-08-13 mouse
Hongchun Li, Wei Xu, Denian Wang, Liang Wang, Qiyao Fang, Xuemei Wan, Jiamei Zhang, Yiming Hu, Huifang Li, Jie Zhang, Zhen Yang, Chunqi Liu, Xiaocong Liu, Yonghai Wang, Bin Liu, Zhengtao Hu, Ying Zhao, Qian Bu, Hongbo Wang, Jingwei Tian, Yinglan Zhao, Xiaobo Ce. 4R Tau Modulates Cocaine-Associated Memory through Adult Dorsal Hippocampal Neurogenesis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 31. 2021-11-22. PMID:34099513. male mice hippocampal expression of tau was significantly decreased during the cocaine-associated memory formation. 2021-11-22 2023-08-13 mouse
Hongchun Li, Wei Xu, Denian Wang, Liang Wang, Qiyao Fang, Xuemei Wan, Jiamei Zhang, Yiming Hu, Huifang Li, Jie Zhang, Zhen Yang, Chunqi Liu, Xiaocong Liu, Yonghai Wang, Bin Liu, Zhengtao Hu, Ying Zhao, Qian Bu, Hongbo Wang, Jingwei Tian, Yinglan Zhao, Xiaobo Ce. 4R Tau Modulates Cocaine-Associated Memory through Adult Dorsal Hippocampal Neurogenesis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 31. 2021-11-22. PMID:34099513. genetic overexpression of four microtubule-binding repeats tau (4r tau) in the mice hippocampus disrupted cocaine memory by suppressing ahn. 2021-11-22 2023-08-13 mouse
Hongchun Li, Wei Xu, Denian Wang, Liang Wang, Qiyao Fang, Xuemei Wan, Jiamei Zhang, Yiming Hu, Huifang Li, Jie Zhang, Zhen Yang, Chunqi Liu, Xiaocong Liu, Yonghai Wang, Bin Liu, Zhengtao Hu, Ying Zhao, Qian Bu, Hongbo Wang, Jingwei Tian, Yinglan Zhao, Xiaobo Ce. 4R Tau Modulates Cocaine-Associated Memory through Adult Dorsal Hippocampal Neurogenesis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 31. 2021-11-22. PMID:34099513. furthermore, 4r tau directly interacted with phosphoinositide 3-kinase (pi3k)-p85 and impaired its nuclear translocation and pi3k-akt signaling, processes required for hippocampal neuron proliferation. 2021-11-22 2023-08-13 mouse
Alireza Moein Alsadat, Farnaz Nikbakht, Hadiseh Hossein Nia, Fereshteh Golab, Yasaman Khadem, Mahmoud Barati, Somayeh Vazifekha. GSK-3β as a target for apigenin-induced neuroprotection against Aβ 25-35 in a rat model of Alzheimer's disease. Neuropeptides. vol 90. 2021-11-22. PMID:34597878. immunohistochemistry and western blot analysis showed that apigenin significantly reduced the hyperphosphorylation of tau levels in the hippocampus. 2021-11-22 2023-08-13 rat
Ryszard Pluta, Stanisław J Czuczwar, Sławomir Januszewski, Mirosław Jabłońsk. The Many Faces of Post-Ischemic Tau Protein in Brain Neurodegeneration of the Alzheimer's Disease Type. Cells. vol 10. issue 9. 2021-11-19. PMID:34571862. the data indicate that an episode of cerebral ischemia activates the damage and death of neurons in the hippocampus in a tau protein-dependent manner, thus determining a novel and important mechanism for the survival and/or death of neuronal cells following ischemia. 2021-11-19 2023-08-13 Not clear
Fabiola Paciello, Marco Rinaudo, Valentina Longo, Sara Cocco, Giulia Conforto, Anna Pisani, Maria Vittoria Podda, Anna Rita Fetoni, Gaetano Paludetti, Claudio Grass. Auditory sensory deprivation induced by noise exposure exacerbates cognitive decline in a mouse model of Alzheimer's disease. eLife. vol 10. 2021-11-19. PMID:34699347. this was associated with earlier hippocampal dysfunction, increased tau phosphorylation, neuroinflammation, and redox imbalance, along with anticipated memory deficits compared to the expected time-course of the neurodegenerative phenotype. 2021-11-19 2023-08-13 mouse