| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hong-Chun Li, Jie Xiao, Yi-Long Huang, Long-Jun Li, Hong Jiang, Li-Xuan Huang, Ting Yang, Ling Yang, Fan L. [Reduction in hypoxia-derived neuroinflammation and dysfunctional glutamate transporters by minocycline may restore hypoxia-injured cognition of neonatal rat]. Sheng li xue bao : [Acta physiologica Sinica] vol 68 issue 2 2017 27108901 |
inflammatory mediators (iba-1, il-1\xce\xb2, tnf-\xce\xb1 and tgf-\xce\xb21), glutamate transporters (eaat1 and eaat2), total tau and phosphorylated tau (phosphorylation sites: tyr18, thr205, thr231, ser396 and ser404) protein expressions in the hippocampus were detected by western blot 7 d after hypoxic exposure. |
2017-04-28 |
2023-01-25 |
rat |
| Hong-Chun Li, Jie Xiao, Yi-Long Huang, Long-Jun Li, Hong Jiang, Li-Xuan Huang, Ting Yang, Ling Yang, Fan L. [Reduction in hypoxia-derived neuroinflammation and dysfunctional glutamate transporters by minocycline may restore hypoxia-injured cognition of neonatal rat]. Sheng li xue bao : [Acta physiologica Sinica] vol 68 issue 2 2017 27108901 |
the protein expression levels of iba-1, il-1\xce\xb2, tnf-\xce\xb1, eaat2 and tau phosphorylated at t231 were increased, but the total tau expression was decreased in the hippocampus of the rats from hy group 7 d after hypoxia exposure. |
2017-04-28 |
2023-01-25 |
rat |
| Gabor G Kovacs, Jasmin Rahimi, Thomas Str\\xc3\\xb6bel, Mirjam I Lutz, G\\xc3\\xbcnther Regelsberger, Nathalie Streichenberger, Armand Perret-Liaudet, Romana H\\xc3\\xb6ftberger, Pawel P Liberski, Herbert Budka, Beata Sikorsk. Tau pathology in Creutzfeldt-Jakob disease revisited. Brain pathology (Zurich, Switzerland) vol 27 issue 3 2017 27377321 |
to determine the spectrum of tau pathologies in cjd, we assessed phospho-tau (ptau) immunoreactivities in 75 sporadic cjd cases including an evaluation of the entorhinal cortex and six hippocampal subregions. |
2017-04-24 |
2023-01-25 |
human |
| Gabor G Kovacs, Jasmin Rahimi, Thomas Str\\xc3\\xb6bel, Mirjam I Lutz, G\\xc3\\xbcnther Regelsberger, Nathalie Streichenberger, Armand Perret-Liaudet, Romana H\\xc3\\xb6ftberger, Pawel P Liberski, Herbert Budka, Beata Sikorsk. Tau pathology in Creutzfeldt-Jakob disease revisited. Brain pathology (Zurich, Switzerland) vol 27 issue 3 2017 27377321 |
however, the pattern of hippocampal tau pathology often deviates from the stages of braak. |
2017-04-24 |
2023-01-25 |
human |
| Robert John Hatch, Yan Wei, Di Xia, J\\xc3\\xbcrgen G\\xc3\\xb6t. Hyperphosphorylated tau causes reduced hippocampal CA1 excitability by relocating the axon initial segment. Acta neuropathologica vol 133 issue 5 2017 28091722 |
a critical role for tau is supported by studies in transgenic mouse models that express the p301l tau mutation found in cases of familial frontotemporal dementia, with the accumulation of hyperphosphorylated tau in the hippocampus causing reductions in hippocampal long-term potentiation and impairments in spatial learning and memory. |
2017-04-20 |
2023-01-26 |
Not clear |
| Keith A Josephs, Melissa E Murray, Nirubol Tosakulwong, Jennifer L Whitwell, David S Knopman, Mary M Machulda, Stephen D Weigand, Bradley F Boeve, Kejal Kantarci, Leonard Petrucelli, Val J Lowe, Clifford R Jack, Ronald C Petersen, Joseph E Parisi, Dennis W Dickso. Tau aggregation influences cognition and hippocampal atrophy in the absence of beta-amyloid: a clinico-imaging-pathological study of primary age-related tauopathy (PART). Acta neuropathologica vol 133 issue 5 2017 28160067 |
tau aggregation influences cognition and hippocampal atrophy in the absence of beta-amyloid: a clinico-imaging-pathological study of primary age-related tauopathy (part). |
2017-04-20 |
2023-01-26 |
Not clear |
| Zhao-Xu Zhang, Rui-Ping Zhao, De-Sheng Wang, Yan-Bing L. Fuzhisan Ameliorates the Memory Deficits in Aged SAMP8 Mice via Decreasing A\\xce\\xb2 Production and Tau Hyperphosphorylation of the Hippocampus. Neurochemical research vol 41 issue 11 2017 27518086 |
fuzhisan ameliorates the memory deficits in aged samp8 mice via decreasing a\xce\xb2 production and tau hyperphosphorylation of the hippocampus. |
2017-04-05 |
2023-01-25 |
rat |
| Xiaoping Du, Matthew B West, Weihua Cheng, Donald L Ewert, Wei Li, Debra Saunders, Rheal A Towner, Robert A Floyd, Richard D Kopk. Ameliorative Effects of Antioxidants on the Hippocampal Accumulation of Pathologic Tau in a Rat Model of Blast-Induced Traumatic Brain Injury. Oxidative medicine and cellular longevity vol 2016 issue 2017 27034735 |
ameliorative effects of antioxidants on the hippocampal accumulation of pathologic tau in a rat model of blast-induced traumatic brain injury. |
2017-03-03 |
2023-01-25 |
rat |
| Xiaoping Du, Matthew B West, Weihua Cheng, Donald L Ewert, Wei Li, Debra Saunders, Rheal A Towner, Robert A Floyd, Richard D Kopk. Ameliorative Effects of Antioxidants on the Hippocampal Accumulation of Pathologic Tau in a Rat Model of Blast-Induced Traumatic Brain Injury. Oxidative medicine and cellular longevity vol 2016 issue 2017 27034735 |
in the current study, we examined the localization patterns of normal tau and the potential blast-induced accumulation of neurotoxic variants of this microtubule-associated protein that are believed to potentiate the neurodegenerative effects associated with synaptic dysfunction in the hippocampus following three successive blast overpressure exposures in nontransgenic rats. |
2017-03-03 |
2023-01-25 |
rat |
| Xiaoping Du, Matthew B West, Weihua Cheng, Donald L Ewert, Wei Li, Debra Saunders, Rheal A Towner, Robert A Floyd, Richard D Kopk. Ameliorative Effects of Antioxidants on the Hippocampal Accumulation of Pathologic Tau in a Rat Model of Blast-Induced Traumatic Brain Injury. Oxidative medicine and cellular longevity vol 2016 issue 2017 27034735 |
we observed a marked increase in the number of both hyperphosphorylated and oligomeric tau-positive hilar mossy cells and somatic accumulation of endogenous tau in oligodendrocytes in the hippocampus. |
2017-03-03 |
2023-01-25 |
rat |
| Yanjing Cao, Lizhen Liang, Jian Xu, Jiali Wu, Yongxing Yan, Ping Lin, Qiang Chen, Fengming Zheng, Qin Wang, Qian Ren, Zengmei Gou, Yifeng D. The effect of Scutellaria baicalensis stem-leaf flavonoids on spatial learning and memory in chronic cerebral ischemia-induced vascular dementia of rats. Acta biochimica et biophysica Sinica vol 48 issue 5 2017 27118553 |
sstf treatment inhibited the tau phosphorylation in both cortex and hippocampus in vad rats. |
2017-02-27 |
2023-01-25 |
rat |
| Charles Liu, Jon Russin, Christianne Heck, Keisuke Kawata, Radhika Adiga, William Yen, Jonathan Lambert, Benjamin Stear, Meng Law, Yvette Marquez, Peter Crino, David Millett, Dianne Langfor. Dysregulation of PINCH signaling in mesial temporal epilepsy. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia vol 36 issue 2017 27838154 |
resected hippocampal tissue from 7 patients with mesial temporal lobe epilepsy (mtle) was assessed by western analyses to measure levels of pinch and hyperphosphorylated tau, as well as changes in phosphorylation levels of associated kinases akt and gsk3\xce\xb2 in comparison to normal control tissue. |
2017-02-06 |
2023-01-26 |
human |
| O Picazo, J Espinosa-Raya, A Briones-Aranda, M Cerb\\xc3\\xb3. Ovariectomy increases the age-induced hyperphosphorylation of Tau at hippocampal CA1. Cognitive processing vol 17 issue 4 2017 27271684 |
in this study, we explore the expression of tau hyperphosphorylation at hippocampus and the performance of rats in an autoshaping learning task at 5, 10 and 15\xc2\xa0months after the ovaries removal. |
2017-02-01 |
2023-01-25 |
rat |
| O Picazo, J Espinosa-Raya, A Briones-Aranda, M Cerb\\xc3\\xb3. Ovariectomy increases the age-induced hyperphosphorylation of Tau at hippocampal CA1. Cognitive processing vol 17 issue 4 2017 27271684 |
a progressive increase in hippocampal tau phosphorylation at ser-396 was observed in either intact or ovariectomized rats. |
2017-02-01 |
2023-01-25 |
rat |
| Bo-Wen Zheng, Li Yang, Xue-Ling Dai, Zhao-Feng Jiang, Han-Chang Huan. Roles of O-GlcNAcylation on amyloid-\\xce\\xb2 precursor protein processing, tau phosphorylation, and hippocampal synapses dysfunction in Alzheimer's disease. Neurological research vol 38 issue 2 2017 27078700 |
roles of o-glcnacylation on amyloid-\xce\xb2 precursor protein processing, tau phosphorylation, and hippocampal synapses dysfunction in alzheimer's disease. |
2017-01-13 |
2023-01-25 |
Not clear |
| Bo-Wen Zheng, Li Yang, Xue-Ling Dai, Zhao-Feng Jiang, Han-Chang Huan. Roles of O-GlcNAcylation on amyloid-\\xce\\xb2 precursor protein processing, tau phosphorylation, and hippocampal synapses dysfunction in Alzheimer's disease. Neurological research vol 38 issue 2 2017 27078700 |
here, we review the roles of o-glcnacylation in app cleavage, tau phosphorylation and hippocampal synapses function. |
2017-01-13 |
2023-01-25 |
Not clear |
| Xue-Yan Li, Fang Wang, Gui-Hai Chen, Xue-Wei Li, Qi-Gang Yang, Lei Cao, Wen-Wen Ya. Inflammatory insult during pregnancy accelerates age-related behavioral and neurobiochemical changes in CD-1 mice. Age (Dordrecht, Netherlands) vol 38 issue 3 2017 27194408 |
the neurobiochemical results indicated that gestational lps exposure also intensified age-related hippocampal changes, including increased amyloid-\xce\xb242, phosphorylated tau, synaptotagmin-1 and gfap, and decreased syntaxin-1 and h4k8ac. |
2017-01-12 |
2023-01-25 |
mouse |
| Mario Merlini, Debora Wanner, Roger M Nitsc. Tau pathology-dependent remodelling of cerebral arteries precedes Alzheimer's disease-related microvascular cerebral amyloid angiopathy. Acta neuropathologica vol 131 issue 5 2017 26988843 |
therefore, we systematically quantified braak tau stage- and cerebral amyloid angiopathy (caa)-dependent alterations in the alpha-smooth muscle actin (\xce\xb1-sma), collagen, and elastin content of leptomeningeal arterioles, small arteries, and medium-sized arteries surrounding the gyrus frontalis medialis (gfm) and hippocampus (hipp), including the sulci, of 17 clinically and pathologically diagnosed ad subjects (braak stage iv-vi) and 28 non-demented control subjects (braak stage i-iv). |
2017-01-06 |
2023-01-25 |
human |
| Montasir Elahi, Zafrul Hasan, Yumiko Motoi, Shin-Ei Matsumoto, Koichi Ishiguro, Nobutaka Hattor. Region-Specific Vulnerability to Oxidative Stress, Neuroinflammation, and Tau Hyperphosphorylation in Experimental Diabetes Mellitus Mice. Journal of Alzheimer's disease : JAD vol 51 issue 4 2016 26923011 |
the hippocampus, midbrain, and cerebellum of aged (14 to 18 months old) non-transgenic (ntg) and transgenic mice overexpressing wild-type human tau (tg601 mice) were evaluated after a treatment with stz. |
2016-12-29 |
2023-01-25 |
mouse |
| Montasir Elahi, Zafrul Hasan, Yumiko Motoi, Shin-Ei Matsumoto, Koichi Ishiguro, Nobutaka Hattor. Region-Specific Vulnerability to Oxidative Stress, Neuroinflammation, and Tau Hyperphosphorylation in Experimental Diabetes Mellitus Mice. Journal of Alzheimer's disease : JAD vol 51 issue 4 2016 26923011 |
tau hyperphosphorylation was also enhanced in the hippocampus, but not in the midbrain or cerebellum. |
2016-12-29 |
2023-01-25 |
mouse |