All Relations between microtubule-associated protein tau and hippocampus

Publication Sentence Publish Date Extraction Date Species
Kunie Ando, Anna Kabova, Virginie Stygelbout, Karelle Leroy, Céline Heraud, Christelle Frédérick, Valérie Suain, Zehra Yilmaz, Michèle Authelet, Robert Dedecker, Marie-Claude Potier, Charles Duyckaerts, Jean-Pierre Brio. Vaccination with Sarkosyl insoluble PHF-tau decrease neurofibrillary tangles formation in aged tau transgenic mouse model: a pilot study. Journal of Alzheimer's disease : JAD. vol 40 Suppl 1. 2015-01-16. PMID:24614899. immunized mutant tau mice had a lower density of hippocampal gallyas-positive neurons. 2015-01-16 2023-08-12 mouse
Yu-Jing Liu, Yu F. [Progress of experimental research on treating Alzheimer's disease by acupuncture]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine. vol 34. issue 3. 2015-01-05. PMID:24758091. senile dementia rats' cognitive capabilities and memory could be improved by reduction of beta-amyloid protein, attenuation of excessive phosphorylation of tau protein, regulation of center neurotransmitter dysmetabolism, oxidation of anti-free radicals, reduction of neuron apoptosis in the cortex and the hippocampus, inhibition of glial cells' differentiation, adjustment of g protein signaling transduction, and improvement of the mitochondrial dysfunction, thus providing experimental evidence for treating ad by acupuncture. 2015-01-05 2023-08-13 rat
João Carlos Diegues, José Rodrigo Pauli, Eliete Luciano, José Alexandre Curiacos de Almeida Leme, Leandro Pereira de Moura, Rodrigo Augusto Dalia, Michel Barbosa de Araújo, Clarice Yoshiko Sibuya, Maria Alice Rostom de Mello, Ricardo José Gome. Spatial memory in sedentary and trained diabetic rats: molecular mechanisms. Hippocampus. vol 24. issue 6. 2015-01-02. PMID:24916112. hippocampus was extracted to determinate protein expression (ir, igf-1r, and app) and phosphorylation (akt-1, akt-2, tau, and β-amyloide proteins) by western blot analysis. 2015-01-02 2023-08-13 rat
João Carlos Diegues, José Rodrigo Pauli, Eliete Luciano, José Alexandre Curiacos de Almeida Leme, Leandro Pereira de Moura, Rodrigo Augusto Dalia, Michel Barbosa de Araújo, Clarice Yoshiko Sibuya, Maria Alice Rostom de Mello, Ricardo José Gome. Spatial memory in sedentary and trained diabetic rats: molecular mechanisms. Hippocampus. vol 24. issue 6. 2015-01-02. PMID:24916112. aerobic exercise decreased tau phosphorylation and app expression, and increased some proteins related to insulin/igf-1 pathway in hippocampus of diabetic rats. 2015-01-02 2023-08-13 rat
Kang Li, Hengchuan Jia, Xiaojun She, Bo Cui, Na Zhang, Xuewei Chen, Chuanxiang Xu, Gaihong An, Qiang M. Role of NMDA receptors in noise-induced tau hyperphosphorylation in rat hippocampus and prefrontal cortex. Journal of the neurological sciences. vol 340. issue 1-2. 2014-12-22. PMID:24685355. role of nmda receptors in noise-induced tau hyperphosphorylation in rat hippocampus and prefrontal cortex. 2014-12-22 2023-08-12 rat
Kang Li, Hengchuan Jia, Xiaojun She, Bo Cui, Na Zhang, Xuewei Chen, Chuanxiang Xu, Gaihong An, Qiang M. Role of NMDA receptors in noise-induced tau hyperphosphorylation in rat hippocampus and prefrontal cortex. Journal of the neurological sciences. vol 340. issue 1-2. 2014-12-22. PMID:24685355. the aim of the present study was to evaluate the role of nmda receptors in noise-induced tau hyperphosphorylation in the rat hippocampus and prefrontal cortex. 2014-12-22 2023-08-12 rat
Kang Li, Hengchuan Jia, Xiaojun She, Bo Cui, Na Zhang, Xuewei Chen, Chuanxiang Xu, Gaihong An, Qiang M. Role of NMDA receptors in noise-induced tau hyperphosphorylation in rat hippocampus and prefrontal cortex. Journal of the neurological sciences. vol 340. issue 1-2. 2014-12-22. PMID:24685355. the levels of tau phosphorylated at ser202 and ser396, and proteins involved in hyperphosphorylation, namely glycogen synthase kinase 3β (gsk3β) and protein phosphatase 2a (pp2a), were measured in the hippocampus and prefrontal cortex (pfc) after the last noise exposure. 2014-12-22 2023-08-12 rat
Kang Li, Hengchuan Jia, Xiaojun She, Bo Cui, Na Zhang, Xuewei Chen, Chuanxiang Xu, Gaihong An, Qiang M. Role of NMDA receptors in noise-induced tau hyperphosphorylation in rat hippocampus and prefrontal cortex. Journal of the neurological sciences. vol 340. issue 1-2. 2014-12-22. PMID:24685355. we showed that phosphorylated tau levels were enhanced in noise-exposed-rat hippocampus and pfc. 2014-12-22 2023-08-12 rat
Kang Li, Hengchuan Jia, Xiaojun She, Bo Cui, Na Zhang, Xuewei Chen, Chuanxiang Xu, Gaihong An, Qiang M. Role of NMDA receptors in noise-induced tau hyperphosphorylation in rat hippocampus and prefrontal cortex. Journal of the neurological sciences. vol 340. issue 1-2. 2014-12-22. PMID:24685355. mk-801 decreased the hyperphosphorylation of tau at ser202 and ser396 sites in the hippocampus and pfc. 2014-12-22 2023-08-12 rat
Kang Li, Hengchuan Jia, Xiaojun She, Bo Cui, Na Zhang, Xuewei Chen, Chuanxiang Xu, Gaihong An, Qiang M. Role of NMDA receptors in noise-induced tau hyperphosphorylation in rat hippocampus and prefrontal cortex. Journal of the neurological sciences. vol 340. issue 1-2. 2014-12-22. PMID:24685355. this suggests that mk-801 protects against chronic-noise-induced tau hyperphosphorylation in the hippocampus and pfc. 2014-12-22 2023-08-12 rat
Kang Li, Hengchuan Jia, Xiaojun She, Bo Cui, Na Zhang, Xuewei Chen, Chuanxiang Xu, Gaihong An, Qiang M. Role of NMDA receptors in noise-induced tau hyperphosphorylation in rat hippocampus and prefrontal cortex. Journal of the neurological sciences. vol 340. issue 1-2. 2014-12-22. PMID:24685355. these findings demonstrate that glu-nmdar signaling may be involved in triggering aberrant tau hyperphosphorylation in the hippocampus and pfc after chronic noise exposure. 2014-12-22 2023-08-12 rat
Ken C Walls, Rahasson R Ager, Vitaly Vasilevko, Dave Cheng, Rodrigo Medeiros, Frank M LaFerl. p-Tau immunotherapy reduces soluble and insoluble tau in aged 3xTg-AD mice. Neuroscience letters. vol 575. 2014-12-22. PMID:24887583. to determine the effectiveness of targeting pathological tau, with aβ pathology present, we administered a single injection of at8, or control antibody, into the hippocampus of aged 3xtg-ad mice. 2014-12-22 2023-08-13 mouse
C Yang, X Guo, G H Wang, H L Wang, Z C Liu, H Liu, Z X Zhu, Y L. Changes in tau phosphorylation levels in the hippocampus and frontal cortex following chronic stress. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 47. issue 3. 2014-12-19. PMID:24652321. changes in tau phosphorylation levels in the hippocampus and frontal cortex following chronic stress. 2014-12-19 2023-08-12 rat
C Yang, X Guo, G H Wang, H L Wang, Z C Liu, H Liu, Z X Zhu, Y L. Changes in tau phosphorylation levels in the hippocampus and frontal cortex following chronic stress. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 47. issue 3. 2014-12-19. PMID:24652321. the main aim of the present study was to investigate possible alterations in the tau protein in the hippocampus and frontal cortex of 32 male sprague-dawley rats exposed to chronic unpredictable mild stress (cums) and then re-exposed to cums to mimic depression and the recurrence of depression, respectively, in humans. 2014-12-19 2023-08-12 rat
Hui-li Liu, Gang Zhao, He Zhang, Li-de Sh. Long-term treadmill exercise inhibits the progression of Alzheimer's disease-like neuropathology in the hippocampus of APP/PS1 transgenic mice. Behavioural brain research. vol 256. 2014-12-18. PMID:23968591. five months of treadmill exercise resulted in a robust reduction in β-amyloid (aβ) deposition and tau phosphorylation in the hippocampus of app/ps1 mice. 2014-12-18 2023-08-12 mouse
Eric C Miller, Peter J Teravskis, Benjamin W Dummer, Xiaohui Zhao, Richard L Huganir, Dezhi Lia. Tau phosphorylation and tau mislocalization mediate soluble Aβ oligomer-induced AMPA glutamate receptor signaling deficits. The European journal of neuroscience. vol 39. issue 7. 2014-12-18. PMID:24713000. here, we show that tau mislocalizes to dendritic spines in cultured hippocampal neurons from appswe alzheimer's disease (ad)-transgenic mice and in cultured rat hippocampal neurons treated with soluble aβ oligomers. 2014-12-18 2023-08-13 mouse
Ge Jin, Li-Hua Wang, Xue-Fei Ji, Tian-Yan Chi, Yue Qi, Qing Jiao, Qian Xu, Xiao-Yu Zhou, Rui Zhang, Li-Bo Zo. Xanthoceraside rescues learning and memory deficits through attenuating beta-amyloid deposition and tau hyperphosphorylation in APP mice. Neuroscience letters. vol 573. 2014-12-18. PMID:24810883. western blotting revealed that xanthoceraside decreased tau phosphorylation protein levels at ser396 and ser404 in the hippocampus; xanthoceraside also decreased app protein levels and gsk-3β phosphorylation. 2014-12-18 2023-08-13 mouse
Shu Yang, Qihai Gong, Qin Wu, Fei Li, Yuanfu Lu, Jingshan Sh. Alkaloids enriched extract from Dendrobium nobile Lindl. attenuates tau protein hyperphosphorylation and apoptosis induced by lipopolysaccharide in rat brain. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 21. issue 5. 2014-12-15. PMID:24268296. the present study demonstrated that ednla attenuates lps-induced hyperphosphorylation of tau protein in rat's hippocampus and protects against lps-induced apoptosis in rat brain. 2014-12-15 2023-08-12 rat
Tomohiro Onishi, Yoshio Matsumoto, Masahiko Hattori, Yuka Obayashi, Kimie Nakamura, Takashi Yano, Takashi Horiguchi, Hiroki Iwashit. Early-onset cognitive deficits and axonal transport dysfunction in P301S mutant tau transgenic mice. Neuroscience research. vol 80. 2014-12-04. PMID:24406748. tau phosphorylation in the hippocampus of tpr50 mice increased with age, particularly at s202/t205. 2014-12-04 2023-08-12 mouse
Tomohiro Onishi, Yoshio Matsumoto, Masahiko Hattori, Yuka Obayashi, Kimie Nakamura, Takashi Yano, Takashi Horiguchi, Hiroki Iwashit. Early-onset cognitive deficits and axonal transport dysfunction in P301S mutant tau transgenic mice. Neuroscience research. vol 80. 2014-12-04. PMID:24406748. insolubilization and intracellular accumulation of tau were detected in the hippocampus by 9 months of age. 2014-12-04 2023-08-12 mouse