Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
Arianna Bellucci, Maria Cristina Rosi, Cristina Grossi, Anna Fiorentini, Ilaria Luccarini, Fiorella Casament. Abnormal processing of tau in the brain of aged TgCRND8 mice. Neurobiology of disease vol 27 issue 3 2007 17656099 |
phf-1 and nitrotyrosine immunoreactivity merged within neurons surrounding amyloid deposits in cortical and hippocampal areas and immunoprecipitation studies confirmed that tau is nitrosylated. |
2007-10-31 |
2023-01-24 |
mouse |
Junko Fujio, Hiroaki Hosono, Koichi Ishiguro, Shiro Ikegami, Shinobu C Fujit. Tau phosphorylation in the mouse brain during aversive conditioning. Neurochemistry international vol 51 issue 2-4 2007 17597257 |
as an initial investigation we chose contextual fear conditioning paradigm involving electric shocks, and studied tau phosphorylation in the hippocampus and a neighboring limbic region of the mouse brain. |
2007-10-25 |
2023-01-24 |
Not clear |
Junko Fujio, Hiroaki Hosono, Koichi Ishiguro, Shiro Ikegami, Shinobu C Fujit. Tau phosphorylation in the mouse brain during aversive conditioning. Neurochemistry international vol 51 issue 2-4 2007 17597257 |
these results suggest involvement of tau and tpki/gsk3beta phosphorylation in an early phase of memory formation in the hippocampus and amygdala, raising a possibility that a dysregulation of tau phosphorylation may underlie memory impairment in incipient alzheimer's disease. |
2007-10-25 |
2023-01-24 |
Not clear |
Diana S Woodruff-Pak, Alexis Agelan, Luis Del Vall. A rabbit model of Alzheimer's disease: valid at neuropathological, cognitive, and therapeutic levels. Journal of Alzheimer's disease : JAD vol 11 issue 3 2007 17851187 |
changes in neurons in the hippocampus were consistent with neurofibrillary degeneration and cytoplasmic immunoreactivity for amyloid-beta and tau. |
2007-10-11 |
2023-01-24 |
rabbit |
G Niewiadomska, M Baksalerska-Pazera, I Lenarcik, G Riede. Compartmental protein expression of Tau, GSK-3beta and TrkA in cholinergic neurons of aged rats. Journal of neural transmission (Vienna, Austria : 1996) vol 113 issue 11 2007 16736240 |
in young animals, expression of tau isoforms and glycogen synthase kinase-3beta (gsk-3beta) was restricted to neuritic structures in cortex, hippocampus, and basal forebrain. |
2007-09-05 |
2023-01-24 |
rat |
S Yoshida, M Maeda, S Kaku, H Ikeya, K Yamada, S Nakaik. Lithium inhibits stress-induced changes in tau phosphorylation in the mouse hippocampus. Journal of neural transmission (Vienna, Austria : 1996) vol 113 issue 11 2007 16855914 |
lithium inhibits stress-induced changes in tau phosphorylation in the mouse hippocampus. |
2007-09-05 |
2023-01-24 |
mouse |
S Yoshida, M Maeda, S Kaku, H Ikeya, K Yamada, S Nakaik. Lithium inhibits stress-induced changes in tau phosphorylation in the mouse hippocampus. Journal of neural transmission (Vienna, Austria : 1996) vol 113 issue 11 2007 16855914 |
in the present study, we investigated the effects of cold water stress (cws) on tau phosphorylation in the mouse hippocampus and the effects of gsk-3beta inhibitor, licl, on cws-induced changes in tau phosphorylation levels by immunoblot analyses. |
2007-09-05 |
2023-01-24 |
mouse |
S Yoshida, M Maeda, S Kaku, H Ikeya, K Yamada, S Nakaik. Lithium inhibits stress-induced changes in tau phosphorylation in the mouse hippocampus. Journal of neural transmission (Vienna, Austria : 1996) vol 113 issue 11 2007 16855914 |
these results suggest that a cws-induced increase in phosphorylated tau in the hippocampus is mediated, at least partly, by the activation of gsk-3beta. |
2007-09-05 |
2023-01-24 |
mouse |
Kristina Sennvik, Karin Boekhoorn, Reena Lasrado, Dick Terwel, Steven Verhaeghe, Hubert Korr, Christoph Schmitz, Takami Tomiyama, Hiroshi Mori, Harm Krugers, Marian Joels, Ger J A Ramakers, Paul J Lucassen, Fred Van Leuve. Tau-4R suppresses proliferation and promotes neuronal differentiation in the hippocampus of tau knockin/knockout mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology vol 21 issue 9 2007 17341679 |
tau-4r suppresses proliferation and promotes neuronal differentiation in the hippocampus of tau knockin/knockout mice. |
2007-08-15 |
2023-01-24 |
mouse |
Robert A Rissman, Kuo-Fen Lee, Wylie Vale, Paul E Sawchenk. Corticotropin-releasing factor receptors differentially regulate stress-induced tau phosphorylation. The Journal of neuroscience : the official journal of the Society for Neuroscience vol 27 issue 24 2007 17567816 |
acute stress can induce hippocampal tau phosphorylation (tau-p) in rodents, but the mechanisms and pathogenic relevance of this response are unclear. |
2007-07-19 |
2023-01-24 |
mouse |
Rhonda L Nelson, Zhihong Guo, Veerendra Madala Halagappa, Michelle Pearson, Audrey J Gray, Yasuji Matsuoka, Martin Brown, Bronwen Martin, Titilola Iyun, Stuart Maudsley, Robert F Clark, Mark P Mattso. Prophylactic treatment with paroxetine ameliorates behavioral deficits and retards the development of amyloid and tau pathologies in 3xTgAD mice. Experimental neurology vol 205 issue 1 2007 17368447 |
female 3xtgad mice exhibited significantly less tau pathology in the hippocampus and amygdala compared to male 3xtgad mice, and paroxetine lessened tau pathology in male 3xtgad mice. |
2007-06-18 |
2023-01-24 |
mouse |
K Ren, J Thinschmidt, J Liu, L Ai, R L Papke, M A King, J A Hughes, E M Meye. alpha7 Nicotinic receptor gene delivery into mouse hippocampal neurons leads to functional receptor expression, improved spatial memory-related performance, and tau hyperphosphorylation. Neuroscience vol 145 issue 1 2007 17218065 |
2 month but not 2 week) expression of high levels of alpha7 receptors in hippocampus increased at8 staining characteristic of hyperphosphorylated tau in that region, indicating that endogenous agonist-mediated receptor activation may be able to modulate this process. |
2007-05-15 |
2023-01-24 |
rat |
Kaoru Sugimori, Katsuji Kobayashi, Tatsuru Kitamura, Satoru Sudo, Yoshifumi Koshin. 14-3-3 protein beta isoform is associated with 3-repeat tau neurofibrillary tangles in Alzheimer's disease. Psychiatry and clinical neurosciences vol 61 issue 2 2007 17362433 |
nft were labeled with gallyas impregnation, tau and 14-3-3 immunohistochemistry in paraffin-embedded hippocampal sections from seven ad and three control brains. |
2007-05-14 |
2023-01-24 |
Not clear |
Tarja M Malm, Henna Iivonen, Gundars Goldsteins, Velta Keksa-Goldsteine, Toni Ahtoniemi, Katja Kanninen, Antero Salminen, Seppo Auriola, Thomas Van Groen, Heikki Tanila, Jari Koistinah. Pyrrolidine dithiocarbamate activates Akt and improves spatial learning in APP/PS1 mice without affecting beta-amyloid burden. The Journal of neuroscience : the official journal of the Society for Neuroscience vol 27 issue 14 2007 17409235 |
in addition, pdtc rescued cultured hippocampal neurons from the toxicity of oligomeric abeta and reduced tau phosphorylation in the hippocampus of ad mice. |
2007-05-02 |
2023-01-24 |
mouse |
Yoshiko Ikeda, Koichi Ishiguro, Shinobu C Fujit. Ether stress-induced Alzheimer-like tau phosphorylation in the normal mouse brain. FEBS letters vol 581 issue 5 2007 17289030 |
here, we report tau phosphorylation in the hippocampus of normal mouse after ether anesthesia, known to trigger typical stress reactions. |
2007-04-17 |
2023-01-24 |
mouse |
Iain C Anthony, Stephen N Ramage, Frances W Carnie, Peter Simmonds, Jeanne E Bel. Accelerated Tau deposition in the brains of individuals infected with human immunodeficiency virus-1 before and after the advent of highly active anti-retroviral therapy. Acta neuropathologica vol 111 issue 6 2007 16718349 |
we find no evidence of significant premature beta amyloid deposition in hiv-infected cases; however, we do observe elevated levels of hyperphosphorylated tau in the hippocampus of many hiv-infected subjects, compared with age-matched controls. |
2007-04-16 |
2023-01-24 |
human |
Iain C Anthony, Stephen N Ramage, Frances W Carnie, Peter Simmonds, Jeanne E Bel. Accelerated Tau deposition in the brains of individuals infected with human immunodeficiency virus-1 before and after the advent of highly active anti-retroviral therapy. Acta neuropathologica vol 111 issue 6 2007 16718349 |
we surmise that hiv infection and/or the use of anti-retroviral therapy may predispose to accelerated neuroageing in the form of hyperphosphorylated tau deposition in the hippocampus. |
2007-04-16 |
2023-01-24 |
human |
N Crespo-Biel, A M Canudas, A Camins, M Pall\\xc3\\xa0. Kainate induces AKT, ERK and cdk5/GSK3beta pathway deregulation, phosphorylates tau protein in mouse hippocampus. Neurochemistry international vol 50 issue 2 2007 17116346 |
kainate induces akt, erk and cdk5/gsk3beta pathway deregulation, phosphorylates tau protein in mouse hippocampus. |
2007-03-30 |
2023-01-24 |
mouse |
Edward Rockenstein, Magdalena Torrance, Anthony Adame, Michael Mante, Pazit Bar-on, John B Rose, Leslie Crews, Eliezer Maslia. Neuroprotective effects of regulators of the glycogen synthase kinase-3beta signaling pathway in a transgenic model of Alzheimer's disease are associated with reduced amyloid precursor protein phosphorylation. The Journal of neuroscience : the official journal of the Society for Neuroscience vol 27 issue 8 2007 17314294 |
happ tg mice that were treated with lithium or that were crossed with dn-gsk3beta tg mice displayed improved performance in the water maze, preservation of the dendritic structure in the frontal cortex and hippocampus, and decreased tau phosphorylation. |
2007-03-22 |
2023-01-24 |
mouse |
Yasumasa Yoshiyama, Makoto Higuchi, Bin Zhang, Shu-Ming Huang, Nobuhisa Iwata, Takaomi C Saido, Jun Maeda, Tetsuya Suhara, John Q Trojanowski, Virginia M-Y Le. Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model. Neuron vol 53 issue 3 2007 17270732 |
filamentous tau lesions developed in p301s tg mice at 6 months of age, and progressively accumulated in association with striking neuron loss as well as hippocampal and entorhinal cortical atrophy by 9-12 months of age. |
2007-03-15 |
2023-01-24 |
mouse |