| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| P Vermersch, J P David, B Frigard, C Fallet-Bianco, A Wattez, H Petit, A Delacourt. Cortical mapping of Alzheimer pathology in brains of aged non-demented subjects. Progress in neuro-psychopharmacology & biological psychiatry vol 19 issue 6 1996 8584681 |
the abnormal tau triplet, a biochemical marker of neurofibrillary degeneration was quantified by western blot and densitometric analysis in several cortical areas including the entorhinal cortex (ec), hippocampus and brodmann areas (ba) 38, 20, 22, 35, 9, 44 and 39. |
1996-03-19 |
2023-01-24 |
human |
| P Vermersch, J P David, B Frigard, C Fallet-Bianco, A Wattez, H Petit, A Delacourt. Cortical mapping of Alzheimer pathology in brains of aged non-demented subjects. Progress in neuro-psychopharmacology & biological psychiatry vol 19 issue 6 1996 8584681 |
the abnormal tau triplet was detected in the ec and the hippocampus of most of the controls aged over 70 years. |
1996-03-19 |
2023-01-24 |
human |
| P Vermersch, J P David, B Frigard, C Fallet-Bianco, A Wattez, H Petit, A Delacourt. Cortical mapping of Alzheimer pathology in brains of aged non-demented subjects. Progress in neuro-psychopharmacology & biological psychiatry vol 19 issue 6 1996 8584681 |
the authors conclude that control cases with tau pathology in the temporal lobe and numerous sp in the neocortex were likely to be subclinical stages of ad whereas others with tau pathology exclusively detected in the ec and hippocampus and without or few sp in the neocortex were related to normal aging. |
1996-03-19 |
2023-01-24 |
human |
| C Schwab, J C Steele, H Akiyama, E G McGeer, P L McGee. Relationship of amyloid beta/A4 protein to the neurofibrillary tangles in Guamanian parkinsonism-dementia. Acta neuropathologica vol 90 issue 3 1996 8525803 |
we studied by immunohistochemistry the occurrence of intracellular and extracellular neurofibrillary tangles in lb in the entorhinal cortex, hippocampus and substantia nigra using antibodies to tau protein and ubiquitin. |
1996-01-19 |
2023-01-24 |
Not clear |
| J G Sheng, R E Mrak, W S Griffi. Microglial interleukin-1 alpha expression in brain regions in Alzheimer's disease: correlation with neuritic plaque distribution. Neuropathology and applied neurobiology vol 21 issue 4 1996 7494597 |
in alzheimer's disease, tau 2+ neuritic plaques occurred with increasing frequency in grey matter of frontal and occipital lobes, temporal lobe, and hippocampus. |
1996-01-11 |
2023-01-24 |
Not clear |
| R Dur\\xc3\\xa1n, M C Arufe, B Arias, M Alfons. Effect of domoic acid on brain amino acid levels. Revista espanola de fisiologia vol 51 issue 1 1995 7569276 |
dose induces changes in the levels of amino acids of neurochemical interest (asp, glu, gly, tau, ala, gaba) in different rat brain regions (hypothalamus, hippocampus, amygdala, striatum, cortex and midbrain). |
1995-11-06 |
2023-01-24 |
rat |
| D Wang, D G Muno. Qualitative and quantitative differences in senile plaque dystrophic neurites of Alzheimer's disease and normal aged brain. Journal of neuropathology and experimental neurology vol 54 issue 4 1995 7602328 |
in cortical and hippocampal plaques in alzheimer's disease (ad) beta app colocalized with cga in a neuritic population largely distinct from the subset of neurites labeled by tau. |
1995-08-10 |
2023-01-24 |
human |
| D Wang, D G Muno. Qualitative and quantitative differences in senile plaque dystrophic neurites of Alzheimer's disease and normal aged brain. Journal of neuropathology and experimental neurology vol 54 issue 4 1995 7602328 |
neocortical and hippocampal plaques, the only common type in a group of elderly non-demented subjects (non-ad), incorporated cga/beta app, but not tau neurites. |
1995-08-10 |
2023-01-24 |
human |
| P M Moran, L S Higgins, B Cordell, P C Mose. Age-related learning deficits in transgenic mice expressing the 751-amino acid isoform of human beta-amyloid precursor protein. Proceedings of the National Academy of Sciences of the United States of America vol 92 issue 12 1995 7777509 |
transgenic mice expressing the 751-amino acid isoform of human beta-app (beta-app751) have been shown to develop early ad-like histopathology with diffuse deposits of beta-a4 and aberrant tau protein expression in the brain, particularly in the hippocampus, cortex, and amygdala. |
1995-07-12 |
2023-01-24 |
mouse |
| C R Breese, R Freedman, S S Leonar. Glutamate receptor subtype expression in human postmortem brain tissue from schizophrenics and alcohol abusers. Brain research vol 674 issue 1 1995 7773698 |
no significant changes were observed in schizophrenic hippocampal glur1 and glur5 receptor subtypes or in levels of the structural control proteins, ncam and tau. |
1995-07-11 |
2023-01-24 |
human |
| J Busciglio, A Lorenzo, J Yeh, B A Yankne. beta-amyloid fibrils induce tau phosphorylation and loss of microtubule binding. Neuron vol 14 issue 4 1995 7718249 |
to determine whether amyloid fibril formation affects the phosphorylation state of tau, primary cultures of fetal rat hippocampal and human cortical neurons were treated with beta-amyloid (beta a) in a soluble, amorphous-aggregated, or fibrillar form. |
1995-05-23 |
2023-01-24 |
rat |
| C Vigo-Pelfrey, P Seubert, R Barbour, C Blomquist, M Lee, D Lee, F Coria, L Chang, B Miller, I Lieberbur. Elevation of microtubule-associated protein tau in the cerebrospinal fluid of patients with Alzheimer's disease. Neurology vol 45 issue 4 1995 7723971 |
postmortem analysis of two ad patients with high levels of csf tau revealed a high density of nfts in the hippocampus. |
1995-05-23 |
2023-01-24 |
human |
| N Arai, M I Papp, P L Lanto. New observation on ubiquitinated neurons in the cerebral cortex of multiple system atrophy (MSA). Neuroscience letters vol 182 issue 2 1995 7715809 |
to investigate neuronal damage in the cerebral cortex in patients with multiple system atrophy (msa), immunohistochemical stainings were carried out on the prefrontal cortex, the hippocampus, the precentral gyrus, the supplementary motor cortex and the occipital cortex in 6 cases of msa and 6 controls, using antibodies against ubiquitin, tau protein and neurofilaments (bf10, rt97, 147). |
1995-05-17 |
2023-01-24 |
Not clear |
| R M Torack, J W Mille. Denervation induced abnormal phosphorylation in hippocampal neurons. Brain research vol 669 issue 1 1995 7712157 |
this study demonstrates that combined dopaminergic and cholinergic denervation of the hippocampus results in the appearance of morphologically altered, tau reactive, apical dendrites of granule cells in the rat dentate gyrus. |
1995-05-12 |
2023-01-24 |
rat |
| T Horn, L Bauce, R Landgraf, Q J Pittma. Microdialysis with high NaCl causes central release of amino acids and dopamine. Journal of neurochemistry vol 64 issue 4 1995 7891091 |
in the dialysates of all perfusion areas, including the son, pvn, hippocampus, and striatum, concentrations of asp, glu, ser, gln, gly, taurine (tau), and gamma-aminobutyric acid (gaba) were significantly increased during perfusion with high-nacl medium. |
1995-04-18 |
2023-01-24 |
rat |
| T D Garver, K A Harris, R A Lehman, V M Lee, J Q Trojanowski, M L Billingsle. Tau phosphorylation in human, primate, and rat brain: evidence that a pool of tau is highly phosphorylated in vivo and is rapidly dephosphorylated in vitro. Journal of neurochemistry vol 63 issue 6 1994 7964748 |
tau was rapidly isolated from human temporal neocortex and hippocampus, rhesus monkey temporal neocortex, and rat temporal neocortex and hippocampus under conditions that minimized dephosphorylation. |
1994-12-23 |
2023-01-24 |
rat |
| C Schwab, V Bondada, D L Sparks, L D Cahan, J W Gedde. Postmortem changes in the levels and localization of microtubule-associated proteins (tau, MAP2 and MAP1B) in the rat and human hippocampus. Hippocampus vol 4 issue 2 1994 7951696 |
postmortem changes in the levels and localization of microtubule-associated proteins (tau, map2 and map1b) in the rat and human hippocampus. |
1994-12-20 |
2023-01-24 |
rat |
| C Schwab, V Bondada, D L Sparks, L D Cahan, J W Gedde. Postmortem changes in the levels and localization of microtubule-associated proteins (tau, MAP2 and MAP1B) in the rat and human hippocampus. Hippocampus vol 4 issue 2 1994 7951696 |
immunohistochemistry and immunoblots were used to examine the microtubule-associated proteins tau, map2, and map1b in the rat hippocampus at various times after death. |
1994-12-20 |
2023-01-24 |
rat |
| R W Shin, V M Lee, J Q Trojanowsk. Aluminum modifies the properties of Alzheimer's disease PHF tau proteins in vivo and in vitro. The Journal of neuroscience : the official journal of the Society for Neuroscience vol 14 issue 11 Pt 2 1994 7525898 |
to determine if aluminum salts interact directly and specifically with phf tau in situ, we pretreated sections of ad hippocampus with 10 mm alcl3 and then probed these sections by immunohistochemistry with antibodies to phf tau as well as to a number of other plaque and tangle components. |
1994-12-02 |
2023-01-24 |
rat |
| H Braak, E Braak, M Strothjohan. Abnormally phosphorylated tau protein related to the formation of neurofibrillary tangles and neuropil threads in the cerebral cortex of sheep and goat. Neuroscience letters vol 171 issue 1-2 1994 7521944 |
frontal sections including temporal isocortex, entorhinal region and hippocampus from aged domestic animals (dog, cat, horse, sheep and goat) were studied for alzheimer-related changes using immunostaining with the at8 antibody for abnormally phosphorylated tau protein and selective silver techniques for a4 amyloid and neurofibrillary changes of the alzheimer type. |
1994-10-10 |
2023-01-24 |
human |